Dnmt3b (DNA methyltransferase 3B) - Rat Genome Database

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Gene: Dnmt3b (DNA methyltransferase 3B) Mus musculus
Analyze
Symbol: Dnmt3b
Name: DNA methyltransferase 3B
RGD ID: 1551604
MGI Page MGI
Description: Enables DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates; DNA binding activity; and lncRNA binding activity. Involved in negative regulation of gene expression, epigenetic. Acts upstream of or within several processes, including cellular response to amino acid stimulus; epigenetic regulation of gene expression; and negative regulation of transcription by RNA polymerase II. Located in chromosome, centromeric region; heterochromatin; and nucleus. Is expressed in several structures, including alimentary system; brain; early conceptus; genitourinary system; and hemolymphoid system. Used to study immunodeficiency-centromeric instability-facial anomalies syndrome 1. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); carcinoma (multiple); facioscapulohumeral muscular dystrophy 4; immunodeficiency-centromeric instability-facial anomalies syndrome 1; and thymoma. Orthologous to human DNMT3B (DNA methyltransferase 3 beta).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: DNA (cytosine-5)-methyltransferase 3B; DNA methyltransferase MmuIIIB; DNA MTase MmuIIIB; m.MmuIIIB; MGC124407; MmuIIIB
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392153,491,332 - 153,529,650 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2153,491,370 - 153,529,650 (+)EnsemblGRCm39 Ensembl
GRCm382153,649,411 - 153,687,730 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2153,649,450 - 153,687,730 (+)EnsemblGRCm38mm10GRCm38
MGSCv372153,475,190 - 153,513,466 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362153,340,895 - 153,379,168 (+)NCBIMGSCv36mm8
Celera2159,495,468 - 159,534,017 (+)NCBICelera
Cytogenetic Map2H1NCBI
cM Map275.79NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acute myeloid leukemia  (ISO)
anxiety disorder  (ISO)
autism spectrum disorder  (ISO)
autoimmune thrombocytopenic purpura  (ISO)
B-Cell Chronic Lymphocytic Leukemia  (ISO)
Breast Neoplasms  (ISO)
carcinoma  (ISO)
chronic myeloid leukemia  (ISO)
colorectal adenocarcinoma  (ISO)
Colorectal Neoplasms  (ISO)
congenital heart disease  (ISO)
Craniofacial Abnormalities  (ISO)
Dysmenorrhea  (ISO)
Endometrial Neoplasms  (ISO)
Endometrioid Carcinomas  (ISO)
endometriosis  (ISO)
endometriosis of uterus  (ISO)
esophagus squamous cell carcinoma  (ISO)
Experimental Mammary Neoplasms  (ISO)
facioscapulohumeral muscular dystrophy 4  (ISO)
Familial Prostate Cancer  (ISO)
Female Infertility  (ISO)
fetal alcohol spectrum disorder  (ISO)
Fetal Growth Retardation  (ISO)
gastric body carcinoma  (ISO)
genetic disease  (ISO)
glutathione synthetase deficiency  (ISO)
glutatione synthetase deficiency with 5-oxoprolinuria  (ISO)
head and neck squamous cell carcinoma  (ISO)
hepatocellular carcinoma  (ISO)
immunodeficiency-centromeric instability-facial anomalies syndrome  (ISO)
immunodeficiency-centromeric instability-facial anomalies syndrome 1  (IAGP,ISO)
Kabuki Syndrome 1  (ISO)
lung adenocarcinoma  (ISO)
lung cancer  (ISO)
lung small cell carcinoma  (ISO)
Lymphatic Metastasis  (ISO)
Multiple Primary Neoplasms  (ISO)
myelodysplastic syndrome  (ISO)
Neoplasm Metastasis  (ISO)
Oral Lichen Planus  (ISO)
oral squamous cell carcinoma  (ISO)
pancreatic ductal carcinoma  (ISO)
primary immunodeficiency disease  (ISO)
prostate adenocarcinoma  (IEP)
Prostatic Neoplasms  (ISO)
prostatitis  (ISO)
rheumatoid arthritis  (ISO)
schizophrenia  (ISO)
skin melanoma  (ISO)
Stomach Neoplasms  (ISO)
thymoma  (ISO)
type 1 diabetes mellitus  (ISO)
Uterine Cervical Neoplasms  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-palmitoylglycerol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3'-diindolylmethane  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (EXP)
3-phenylprop-2-enal  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-nitro-m-cresol  (EXP)
4-nonylphenol  (ISO)
4-tert-Octylphenol  (ISO)
5-aza-2'-deoxycytidine  (EXP,ISO)
5-azacytidine  (EXP,ISO)
5-fluorouracil  (EXP)
6-propyl-2-thiouracil  (ISO)
8-hydroxy-2'-deoxyguanosine  (ISO)
acetic acid  (EXP)
acetylsalicylic acid  (EXP)
acrylamide  (EXP,ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (EXP,ISO)
allethrin  (ISO)
amphetamine  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (EXP,ISO)
asiatic acid  (ISO)
azathioprine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzophenanthridine  (ISO)
berberine  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
bisphenol F  (EXP)
bromobenzene  (ISO)
bromochloroacetic acid  (EXP)
buta-1,3-diene  (EXP)
Butylparaben  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
calcitriol  (ISO)
carbon nanotube  (EXP)
CGP 52608  (ISO)
choline  (EXP)
cisplatin  (EXP,ISO)
cocaine  (EXP)
copper(II) sulfate  (ISO)
curcumin  (EXP,ISO)
cyclophosphamide  (ISO)
cyclosporin A  (ISO)
cyhalothrin  (ISO)
cypermethrin  (ISO)
D-penicillamine  (EXP)
DDT  (ISO)
desferrioxamine B  (ISO)
dexamethasone  (EXP)
Diallyltetrasulfane  (ISO)
diarsenic trioxide  (EXP,ISO)
dibenz[a,h]anthracene  (EXP)
dibutyl phthalate  (EXP,ISO)
dicrotophos  (ISO)
diethylstilbestrol  (EXP,ISO)
diphenylcyclopropenone  (ISO)
disodium selenite  (EXP)
dorsomorphin  (ISO)
endosulfan  (ISO)
entinostat  (EXP,ISO)
ethanol  (EXP,ISO)
etoposide  (ISO)
fenvalerate  (ISO)
folic acid  (EXP,ISO)
formaldehyde  (ISO)
FR900359  (ISO)
fulvestrant  (EXP,ISO)
fumonisin B1  (ISO)
gemcitabine  (ISO)
genistein  (ISO)
gentamycin  (ISO)
gibberellin A3  (ISO)
glycine betaine  (EXP)
glyphosate  (ISO)
guggulsterone  (ISO)
hydrogen peroxide  (ISO)
hydroquinone  (ISO)
indole-3-methanol  (ISO)
isoprenaline  (EXP)
isorhapontigenin  (ISO)
ketamine  (ISO)
ketoconazole  (ISO)
L-methionine  (EXP)
lead(0)  (ISO)
leflunomide  (ISO)
LY294002  (ISO)
malathion  (ISO)
menadione  (ISO)
methoxychlor  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
microcystin-LR  (ISO)
Monobutylphthalate  (EXP)
morphine  (EXP)
N-acetyl-L-cysteine  (EXP,ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (EXP)
ozone  (ISO)
p-tert-Amylphenol  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
PCB138  (EXP)
pelargonidin  (EXP)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
phenobarbital  (EXP,ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (EXP)
potassium chromate  (ISO)
potassium dichromate  (ISO)
procyanidin B2  (ISO)
pterostilbene  (ISO)
pyrethrins  (ISO)
quartz  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
streptozocin  (EXP,ISO)
sulforaphane  (ISO)
tamoxifen  (EXP,ISO)
tangeretin  (EXP)
testosterone  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (ISO)
tributylstannane  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
triptonide  (EXP)
uranium atom  (ISO)
valproic acid  (EXP,ISO)
vanillin  (ISO)
vinclozolin  (ISO)
vinyl carbamate  (EXP)
withaferin A  (ISO)
wortmannin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal blood vessel morphology  (IEA)
abnormal craniofacial morphology  (IEA)
abnormal cranium morphology  (IAGP)
abnormal DNA methylation  (IAGP)
abnormal epigenetic regulation of gene expression  (IAGP)
abnormal facial morphology  (IEA)
abnormal head morphology  (IAGP)
abnormal head shape  (IEA)
abnormal interventricular septum morphology  (IAGP)
abnormal nasal bone morphology  (IAGP)
abnormal placenta morphology  (IEA)
abnormal placenta vasculature  (IEA)
abnormal skeleton morphology  (IAGP)
absent somites  (IAGP)
cleft palate  (IEA)
decreased birth weight  (IAGP)
decreased body height  (IAGP)
decreased body size  (IAGP)
decreased double-positive T cell number  (IAGP)
decreased embryo size  (IAGP)
decreased thymocyte number  (IAGP)
decreased tumor incidence  (IAGP)
edema  (IEA)
embryonic growth retardation  (IAGP)
embryonic lethality during organogenesis, incomplete penetrance  (IAGP)
embryonic lethality, complete penetrance  (IAGP)
enlarged frontal bone  (IAGP)
enlarged interparietal bone  (IAGP)
hemorrhage  (IAGP)
incomplete embryo turning  (IAGP)
incomplete rostral neuropore closure  (IAGP)
increased double-negative T cell number  (IAGP)
increased thymocyte apoptosis  (IAGP)
large anterior fontanelle  (IAGP)
lethality throughout fetal growth and development, complete penetrance  (IAGP)
lumbar vertebral transformation  (IAGP)
microcephaly  (IEA)
microphthalmia  (IEA)
neonatal lethality, complete penetrance  (IAGP)
neonatal lethality, incomplete penetrance  (IAGP)
ocular hypertelorism  (IAGP)
open neural tube  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
prenatal lethality, complete penetrance  (IAGP)
preweaning lethality, complete penetrance  (IEA)
preweaning lethality, incomplete penetrance  (IAGP)
short nasal bone  (IAGP)
short snout  (IAGP)
small liver  (IAGP)
small thymus  (IAGP)
thoracic vertebral transformation  (IAGP)
wide frontal bone  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Genetic sequence variants and the development of secondary primary cancers in patients with head and neck cancers. Azad AK, etal., Cancer. 2012 Mar 15;118(6):1554-65. doi: 10.1002/cncr.26446. Epub 2011 Aug 25.
2. A review of methionine dependency and the role of methionine restriction in cancer growth control and life-span extension. Cavuoto P and Fenech MF, Cancer Treat Rev. 2012 Oct;38(6):726-36. doi: 10.1016/j.ctrv.2012.01.004. Epub 2012 Feb 17.
3. The role of DNA methyltransferase 3b in esophageal squamous cell carcinoma. Chen MF, etal., Cancer. 2012 Aug 15;118(16):4074-89. doi: 10.1002/cncr.26736. Epub 2011 Dec 27.
4. Significance of DNMT3b in oral cancer. Chen WC, etal., PLoS One. 2014 Mar 13;9(3):e89956. doi: 10.1371/journal.pone.0089956. eCollection 2014.
5. Association of the DNMT3B -579G>T polymorphism with risk of thymomas in patients with myasthenia gravis. Coppede F, etal., PLoS One. 2013 Nov 19;8(11):e80846. doi: 10.1371/journal.pone.0080846. eCollection 2013.
6. Vinclozolin exposure in utero induces postpubertal prostatitis and reduces sperm production via a reversible hormone-regulated mechanism. Cowin PA, etal., Endocrinology. 2010 Feb;151(2):783-92. doi: 10.1210/en.2009-0982. Epub 2010 Jan 7.
7. Cancer epigenetics: from mechanism to therapy. Dawson MA and Kouzarides T, Cell. 2012 Jul 6;150(1):12-27. doi: 10.1016/j.cell.2012.06.013.
8. Genetic variants of methyl metabolizing enzymes and epigenetic regulators: associations with promoter CpG island hypermethylation in colorectal cancer. de Vogel S, etal., Cancer Epidemiol Biomarkers Prev. 2009 Nov;18(11):3086-96. doi: 10.1158/1055-9965.EPI-09-0289. Epub 2009 Oct 20.
9. Playing TETris with DNA modifications. Delatte B, etal., EMBO J. 2014 Jun 2;33(11):1198-211. doi: 10.15252/embj.201488290. Epub 2014 May 13.
10. Promoter polymorphisms of DNMT3B and the risk of colorectal cancer in Chinese: a case-control study. Fan H, etal., J Exp Clin Cancer Res. 2008 Jul 28;27:24. doi: 10.1186/1756-9966-27-24.
11. Alteration in methylation pattern of GATA-4 promoter region in vitamin A-deficient offspring's heart. Feng Y, etal., J Nutr Biochem. 2013 Jul;24(7):1373-80. doi: 10.1016/j.jnutbio.2012.11.005. Epub 2013 Jan 17.
12. [Expression and significance of DNA methyltransferase in sera of patients with lung cancer]. Feng YJ, etal., Zhonghua Yi Xue Za Zhi. 2013 Dec 24;93(48):3822-5.
13. DNMT3B (C46359T) polymorphisms and immunoexpression of DNMT3b and DNMT1 proteins in oral lichen planus. Fonseca-Silva T, etal., Pathobiology. 2012;79(1):18-23. doi: 10.1159/000330171. Epub 2012 Jan 12.
14. Fetal Alcohol Exposure Reduces Dopamine Receptor D2 and Increases Pituitary Weight and Prolactin Production via Epigenetic Mechanisms. Gangisetty O, etal., PLoS One. 2015 Oct 28;10(10):e0140699. doi: 10.1371/journal.pone.0140699. eCollection 2015.
15. Association of the DNMT3B polymorphism with colorectal adenomatous polyps and adenocarcinoma. Guo X, etal., Mol Biol Rep. 2010 Jan;37(1):219-25. doi: 10.1007/s11033-009-9626-z. Epub 2009 Jul 22.
16. Age-associated alteration of gene expression patterns in mouse oocytes. Hamatani T, etal., Hum Mol Genet 2004 Oct 1;13(19):2263-78. Epub 2004 Aug 18.
17. High DNA methyltransferase DNMT3B levels: a poor prognostic marker in acute myeloid leukemia. Hayette S, etal., PLoS One. 2012;7(12):e51527. doi: 10.1371/journal.pone.0051527. Epub 2012 Dec 10.
18. The 46359CT polymorphism of DNMT3B is associated with the risk of cervical cancer. Hernandez-Sotelo D, etal., Mol Biol Rep. 2013 Jul;40(7):4275-80. doi: 10.1007/s11033-013-2511-9. Epub 2013 May 16.
19. DNA methyltransferase 3B (DNMT3B -579G>T) promotor polymorphism and the susceptibility to pediatric immune thrombocytopenic purpura in Egypt. Khorshied MM and El-Ghamrawy MK, Gene. 2012 Dec 10;511(1):34-7. doi: 10.1016/j.gene.2012.09.024. Epub 2012 Sep 18.
20. Expression analysis of the epigenetic methyltransferases and methyl-CpG binding protein families in the normal B-cell and B-cell chronic lymphocytic leukemia (CLL). Kn H, etal., Cancer Biol Ther. 2004 Oct;3(10):989-94. Epub 2004 Oct 2.
21. DNMT3B polymorphisms and risk of primary lung cancer. Lee SJ, etal., Carcinogenesis. 2005 Feb;26(2):403-9. Epub 2004 Nov 4.
22. Abnormal DNA methylation in CD4+ T cells from people with latent autoimmune diabetes in adults. Li Y, etal., Diabetes Res Clin Pract. 2011 Nov;94(2):242-8. doi: 10.1016/j.diabres.2011.07.027. Epub 2011 Aug 23.
23. [The C46359T polymorphism of DNMT3B promoter gene and pathogenesis of acute leukemia]. Li Y, etal., Zhonghua Nei Ke Za Zhi. 2005 Aug;44(8):588-91.
24. Aberrant immunoreactivity of deoxyribonucleic acid methyltransferases in adenomyosis. Liu X and Guo SW, Gynecol Obstet Invest. 2012;74(2):100-8. Epub 2012 May 4.
25. Polymorphisms of the DNMT3B gene and risk of squamous cell carcinoma of the head and neck: a case-control study. Liu Z, etal., Cancer Lett. 2008 Sep 8;268(1):158-65. doi: 10.1016/j.canlet.2008.03.034. Epub 2008 May 1.
26. Role of de novo DNA methyltransferases and methyl CpG-binding proteins in gene silencing in a rat hepatoma. Majumder S, etal., J Biol Chem. 2002 May 3;277(18):16048-58. Epub 2002 Feb 13.
27. MGDs mouse GO annotations MGD data from the GO Consortium
28. MGD IEA MGD IEA
29. Expression of DNA methyltransferases DNMT1, 3A, and 3B in normal hematopoiesis and in acute and chronic myelogenous leukemia. Mizuno S, etal., Blood. 2001 Mar 1;97(5):1172-9.
30. DNA methylation pathway alterations in an autochthonous murine model of prostate cancer. Morey SR, etal., Cancer Res. 2006 Dec 15;66(24):11659-67.
31. The -283C/T polymorphism of the DNMT3B gene influences the progression of joint destruction in rheumatoid arthritis. Nam EJ, etal., Rheumatol Int. 2010 Aug;30(10):1299-303. doi: 10.1007/s00296-009-1141-y. Epub 2009 Sep 24.
32. Downregulation of microRNA-29c is associated with hypermethylation of tumor-related genes and disease outcome in cutaneous melanoma. Nguyen T, etal., Epigenetics. 2011 Mar;6(3):388-94. Epub 2011 Mar 1.
33. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
34. DNA methyltransferase expression and DNA hypermethylation in human hepatocellular carcinoma. Park HJ, etal., Cancer Lett. 2006 Feb 28;233(2):271-8.
35. Correlations among PPARgamma, DNMT1, and DNMT3B Expression Levels and Pancreatic Cancer. Pazienza V, etal., PPAR Res. 2012;2012:461784. doi: 10.1155/2012/461784. Epub 2012 Aug 8.
36. Prenatal caffeine ingestion induces aberrant DNA methylation and histone acetylation of steroidogenic factor 1 and inhibits fetal adrenal steroidogenesis. Ping J, etal., Toxicology. 2014 Jul 3;321:53-61. doi: 10.1016/j.tox.2014.03.011. Epub 2014 Apr 6.
37. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
38. Methylation and miRNA effects of resveratrol on mammary tumors vs. normal tissue. Qin W, etal., Nutr Cancer. 2014;66(2):270-7. doi: 10.1080/01635581.2014.868910. Epub 2014 Jan 21.
39. Mouse MP Annotation Import Pipeline RGD automated import pipeline
40. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
41. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
42. Epigenetic silencing of PTPRR activates MAPK signaling, promotes metastasis and serves as a biomarker of invasive cervical cancer. Su PH, etal., Oncogene. 2013 Jan 3;32(1):15-26. doi: 10.1038/onc.2012.29. Epub 2012 Feb 13.
43. Expression pattern and clinical significance of DNA methyltransferase 3B variants in gastric carcinoma. Su X, etal., Oncol Rep. 2010 Mar;23(3):819-26.
44. Decreased DNA methyltransferase 3A and 3B mRNA expression in peripheral blood mononuclear cells and increased plasma SAH concentration in adult patients with idiopathic thrombocytopenic purpura. Tao J, etal., J Clin Immunol. 2008 Sep;28(5):432-9. doi: 10.1007/s10875-008-9223-2. Epub 2008 Aug 6.
45. Gestational hypoxia induces sex-differential methylation of Crhr1 linked to anxiety-like behavior. Wang X, etal., Mol Neurobiol. 2013 Dec;48(3):544-55. doi: 10.1007/s12035-013-8444-4. Epub 2013 Mar 26.
46. Aberrant expression of deoxyribonucleic acid methyltransferases DNMT1, DNMT3A, and DNMT3B in women with endometriosis. Wu Y, etal., Fertil Steril. 2007 Jan;87(1):24-32. Epub 2006 Nov 1.
47. Opposite alterations of DNA methyltransferase gene expression in endometrioid and serous endometrial cancers. Xiong Y, etal., Gynecol Oncol. 2005 Mar;96(3):601-9.
48. Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene. Xu GL, etal., Nature. 1999 Nov 11;402(6758):187-91.
49. DNA methyltransferase 3B gene increases risk of early onset schizophrenia. Zhang C, etal., Neurosci Lett. 2009 Oct 25;462(3):308-11. doi: 10.1016/j.neulet.2009.06.085. Epub 2009 Jul 2.
50. [Association of DNA methyltransferase 3B gene polymorphism with early-onset schizophrenia]. Zhang C, etal., Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2010 Dec;27(6):697-9. doi: 10.3760/cma.j.issn.1003-9406.2010.06.022.
51. Association between DNA methyltransferases 3B gene polymorphisms and the susceptibility to acute myeloid leukemia in Chinese Han population. Zheng Q, etal., PLoS One. 2013 Sep 17;8(9):e74626. doi: 10.1371/journal.pone.0074626. eCollection 2013.
Additional References at PubMed
PMID:9662389   PMID:10555141   PMID:10575238   PMID:10588719   PMID:10922068   PMID:11836534   PMID:11919202   PMID:11934864   PMID:12138111   PMID:12351185   PMID:12370304   PMID:12466851  
PMID:12477932   PMID:12801642   PMID:12869530   PMID:12879017   PMID:12897133   PMID:14519686   PMID:14610273   PMID:14681479   PMID:14998934   PMID:14998998   PMID:15063176   PMID:15120635  
PMID:15215868   PMID:15310660   PMID:15456861   PMID:15456878   PMID:15522198   PMID:15533817   PMID:15567719   PMID:15616584   PMID:15634679   PMID:15671018   PMID:15672446   PMID:15735669  
PMID:15739230   PMID:15757890   PMID:15919778   PMID:16085498   PMID:16141072   PMID:16247769   PMID:16288735   PMID:16395332   PMID:16439359   PMID:16501171   PMID:16543361   PMID:16565708  
PMID:16581773   PMID:16627687   PMID:16631596   PMID:16725135   PMID:16824199   PMID:16973295   PMID:17048991   PMID:17182866   PMID:17369397   PMID:17420264   PMID:17445268   PMID:17485486  
PMID:17579209   PMID:17616512   PMID:17687327   PMID:17726103   PMID:17938196   PMID:17982445   PMID:17994007   PMID:18056424   PMID:18157120   PMID:18241125   PMID:18452947   PMID:18536344  
PMID:18541703   PMID:18544626   PMID:18559477   PMID:18563322   PMID:18567530   PMID:18667590   PMID:18784354   PMID:18799693   PMID:18814855   PMID:18932249   PMID:18953337   PMID:19109157  
PMID:19228594   PMID:19482874   PMID:19509302   PMID:19650037   PMID:19796622   PMID:19798101   PMID:20059948   PMID:20132320   PMID:20348135   PMID:20439742   PMID:20489138   PMID:20507910  
PMID:20548288   PMID:20569692   PMID:20573497   PMID:20587527   PMID:20889571   PMID:20952535   PMID:20966256   PMID:21057502   PMID:21233130   PMID:21267068   PMID:21378119   PMID:21452232  
PMID:21454628   PMID:21490393   PMID:21576263   PMID:21589869   PMID:21608077   PMID:21624812   PMID:21666347   PMID:21695170   PMID:21731673   PMID:21791604   PMID:21873635   PMID:21905163  
PMID:22133874   PMID:22190484   PMID:22269950   PMID:22516971   PMID:22559742   PMID:22580371   PMID:22761581   PMID:22847467   PMID:22898819   PMID:23094090   PMID:23293288   PMID:23302691  
PMID:23315164   PMID:23393137   PMID:23611774   PMID:23636699   PMID:23637617   PMID:23641003   PMID:23754746   PMID:23825703   PMID:23866265   PMID:23920106   PMID:23926181   PMID:24025402  
PMID:24074865   PMID:24127215   PMID:24183668   PMID:24292811   PMID:24357321   PMID:24362762   PMID:24457600   PMID:24597547   PMID:24645644   PMID:24698270   PMID:24803651   PMID:24834974  
PMID:24837369   PMID:24944101   PMID:24952961   PMID:25130491   PMID:25335909   PMID:25389311   PMID:25476147   PMID:25569111   PMID:25607372   PMID:25637539   PMID:25639876   PMID:25680957  
PMID:25686699   PMID:25713087   PMID:25766529   PMID:25784084   PMID:25822089   PMID:26003733   PMID:26023099   PMID:26030024   PMID:26059604   PMID:26098432   PMID:26339596   PMID:26417043  
PMID:26417967   PMID:26576615   PMID:26595813   PMID:26667181   PMID:26729896   PMID:26808831   PMID:26812015   PMID:26854227   PMID:26923591   PMID:26952936   PMID:27122033   PMID:27133822  
PMID:27426728   PMID:27586544   PMID:27681438   PMID:27768276   PMID:27824296   PMID:27826835   PMID:27841881   PMID:27856912   PMID:27865785   PMID:27895551   PMID:27956497   PMID:28106784  
PMID:28215635   PMID:28225755   PMID:28317850   PMID:28321121   PMID:28425913   PMID:28614801   PMID:28712951   PMID:28740121   PMID:29024060   PMID:29027601   PMID:29146735   PMID:29162810  
PMID:29164502   PMID:29309623   PMID:29396184   PMID:29637597   PMID:29765016   PMID:30186101   PMID:30258352   PMID:30321403   PMID:30468428   PMID:30487604   PMID:30518531   PMID:30540937  
PMID:30644360   PMID:30718529   PMID:30850438   PMID:30975723   PMID:31027045   PMID:31285763   PMID:31530896   PMID:31534049   PMID:31558711   PMID:31665063   PMID:31733201   PMID:32051335  
PMID:32058953   PMID:32064321   PMID:32123907   PMID:32183852   PMID:32265226   PMID:32514790   PMID:32561758   PMID:32581223   PMID:32639005   PMID:32916696   PMID:33004076   PMID:33004415  
PMID:33008598   PMID:33230114   PMID:33277576   PMID:33418509   PMID:33450231   PMID:33588625   PMID:33793661   PMID:33846253   PMID:34175897   PMID:34321999   PMID:34439754   PMID:34571854  
PMID:34773530   PMID:34879184   PMID:34947856   PMID:35269409   PMID:35422896   PMID:35725453   PMID:35858425   PMID:36163261   PMID:36178098   PMID:36439251   PMID:36675131   PMID:36690616  
PMID:36690623   PMID:36739439   PMID:37163450   PMID:37217538   PMID:37294637   PMID:37306827   PMID:37462502   PMID:37660134   PMID:37703946   PMID:37979214   PMID:38051594   PMID:38194455  
PMID:38237590   PMID:38295174   PMID:38335290   PMID:38355793   PMID:38413962   PMID:38523790   PMID:38795327   PMID:39023272  


Genomics

Comparative Map Data
Dnmt3b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392153,491,332 - 153,529,650 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2153,491,370 - 153,529,650 (+)EnsemblGRCm39 Ensembl
GRCm382153,649,411 - 153,687,730 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2153,649,450 - 153,687,730 (+)EnsemblGRCm38mm10GRCm38
MGSCv372153,475,190 - 153,513,466 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362153,340,895 - 153,379,168 (+)NCBIMGSCv36mm8
Celera2159,495,468 - 159,534,017 (+)NCBICelera
Cytogenetic Map2H1NCBI
cM Map275.79NCBI
DNMT3B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382032,762,385 - 32,809,356 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2032,762,385 - 32,809,359 (+)EnsemblGRCh38hg38GRCh38
GRCh372031,350,191 - 31,397,162 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362030,813,852 - 30,860,823 (+)NCBINCBI36Build 36hg18NCBI36
Celera2028,104,119 - 28,151,087 (+)NCBICelera
Cytogenetic Map20q11.21NCBI
HuRef2028,137,312 - 28,184,284 (+)NCBIHuRef
CHM1_12031,253,633 - 31,300,607 (+)NCBICHM1_1
T2T-CHM13v2.02034,489,113 - 34,536,082 (+)NCBIT2T-CHM13v2.0
Dnmt3b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83162,590,777 - 162,629,313 (+)NCBIGRCr8
mRatBN7.23142,130,588 - 142,169,128 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3142,130,592 - 142,169,124 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3146,032,579 - 146,071,202 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03154,616,397 - 154,655,021 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03152,356,679 - 152,395,302 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03149,131,541 - 149,170,061 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3149,131,785 - 149,208,786 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03155,510,828 - 155,591,435 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43144,030,737 - 144,069,265 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13143,936,358 - 143,974,887 (+)NCBI
Celera3140,873,202 - 140,910,431 (+)NCBICelera
Cytogenetic Map3q41NCBI
Dnmt3b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542228,380,591 - 28,421,301 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542228,380,595 - 28,427,012 (-)NCBIChiLan1.0ChiLan1.0
DNMT3B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22138,453,003 - 38,499,976 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12038,446,101 - 38,493,074 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02029,049,993 - 29,096,957 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12030,169,081 - 30,215,487 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2030,186,069 - 30,215,487 (+)Ensemblpanpan1.1panPan2
DNMT3B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12422,096,386 - 22,123,378 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2422,096,349 - 22,122,900 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2421,724,710 - 21,769,260 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02422,765,878 - 22,810,458 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2422,782,662 - 22,810,452 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12422,042,034 - 22,086,566 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02422,150,746 - 22,195,021 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02422,581,755 - 22,626,058 (+)NCBIUU_Cfam_GSD_1.0
Dnmt3b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640171,116,001 - 171,139,372 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493648519,547,836 - 19,570,716 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DNMT3B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1736,345,816 - 36,386,072 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11736,345,715 - 36,386,076 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21741,282,731 - 41,322,908 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DNMT3B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1237,128,635 - 37,176,033 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl237,146,538 - 37,174,570 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605089,724,034 - 89,772,846 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dnmt3b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248426,450,852 - 6,475,785 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248426,450,972 - 6,505,929 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Dnmt3b
2027 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:5490
Count of miRNA genes:466
Interacting mature miRNAs:570
Transcripts:ENSMUST00000056495, ENSMUST00000072997, ENSMUST00000081628, ENSMUST00000088976, ENSMUST00000103150, ENSMUST00000103151, ENSMUST00000109771, ENSMUST00000109772, ENSMUST00000109773, ENSMUST00000109774, ENSMUST00000132132, ENSMUST00000140811
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301907Rends_mrenal disease susceptibility (mouse)Not determined2135699221169699361Mouse
1301783Bhr1_mbronchial hyperresponsiveness 1 (mouse)Not determined2142593476178442452Mouse
12790983Bwq12_mbody weight QTL 12 (mouse)2148238204181755017Mouse
1301019Bmd6_mbone mineral density 6 (mouse)Not determined2151778297181755017Mouse
12910799Pwgrq2_mpre-weaning growth rate QTL 2 (mouse)2118589253160611165Mouse
1558939Gnf1_mgrowth and fatness 1 (mouse)Not determined2143773445169117924Mouse
13825247Agoc2_magouti coat color QTL 2 (mouse)2151841920159841920Mouse
12910795Pwbwq5_mpost-weaning body weight QTL 5 (mouse)2118589253160611165Mouse
1300867Lore2_mloss of righting induced by ethanol 2 (mouse)Not determined2144515861180896594Mouse
1558917Gct8_mgranulosa cell tumorigenesis 8 (mouse)Not determined2149236907181755017Mouse
27226761Feml18_mfemur length 18, 16 week (mouse)294230345154241920Mouse
12910812Pwgrq1_mpre-weaning growth rate QTL 1 (mouse)2118589253160611165Mouse
12910814Pwbwq1_mpre-weaning body weight QTL 1 (mouse)2118589253160611165Mouse
14747002Mancz3_mmandible centroid size 3 (mouse)2152329820181755017Mouse
1300751Bdt1_mbone density traits 1 (mouse)Not determined2149988902181755017Mouse
10045885Cplaq15_mcircadian period of locomotor activity 15 (mouse)Not determined2110916118154354667Mouse
10054066Bwq9_mbody weight QTL 9 (mouse)Not determined2135699221169699361Mouse
1301822Pgia2_mproteoglycan induced arthritis 2 (mouse)Not determined2123937311157937424Mouse
10043956Gnf5_mgrowth and fatness 5 (mouse)Not determined2135699221169699361Mouse
1558842Tailq2_mtail length QTL 2 (mouse)Not determined2151640941162737074Mouse
5491197Mobq5_mmultigenic obesity QTL 5 (mouse)Not determined265269746162518926Mouse
10412080Hylaq2_mHyperlocomotor activity related QTL 2 (mouse)Not determined2151640941164119146Mouse
5491196Mobq6_mmultigenic obesity QTL 6 (mouse)Not determined285724269180896594Mouse
1357862Epfq1_mepididymal fat pad weight QTL 1 (mouse)Not determined2151640941162737074Mouse
1301031Bdln3_mbody length 3 (mouse)Not determined2127664019161664118Mouse
11341717Rvfs1_mRift Valley fever susceptibility 1 (mouse)2135432544173449616Mouse
4141703Chlq13_mcirculating hormone level QTL 13 (mouse)Not determined2135699221169699361Mouse
1357484Bsbob_mBSB obesity (mouse)Not determined2143773445165665019Mouse
27226788Feml13_mfemur length 13, 10 week (mouse)2102630345159941920Mouse
4142211Nilac3_mnicotine induced locomotor activity 3 (mouse)Not determined2148664893181755017Mouse
1301294Hrtfm5_mheart failure modifier 5 (mouse)Not determined2122883015156883131Mouse
1558867Gnf3_mgrowth and fatness 3 (mouse)Not determined2152699221169117924Mouse
11038701Ltpr2e_mLeishmania tropica response 2e (mouse)2150212221181755017Mouse
11038702Ltpr2_mLeishmania tropica response 2 (mouse)2103095716167212356Mouse
4142450Lmr16_mleishmaniasis resistance 16 (mouse)Not determined2150212221181755017Mouse
1301085Lrnx10_mlearning-contextual 10 (mouse)Not determined2150212221181755017Mouse
11353826Bdln10_mbody length 10 (mouse)2140441482174441482Mouse
1558852Gnf2_mgrowth and fatness 2 (mouse)Not determined2152699221162197085Mouse
1300806Aod4_mautoimmune ovarian dysgenesis 4 (mouse)Not determined2145228719179228841Mouse
4141033Wg2d_mweight gain in high growth mice 2d (mouse)Not determined143773445160303008Mouse
1357772Scfq1_msubcutaneous fat pad weight QTL 1 (mouse)Not determined2151640941162737074Mouse
1301961Bts1_mbladder tumor susceptibility 1 (mouse)Not determined2132024159166024330Mouse
1301618Bglu1_mblood glucose level 1 (mouse)Not determined2117942930174324863Mouse
27226749Femd10_mfemur midshaft diameter 10, 16 week (mouse)2124441920168241920Mouse
13524521Bodwtq2_mbody wweight QTL 2 (mouse)2153456184156386184Mouse
1302143Bwq5_mbody weight (mouse)Not determined2127664019161664118Mouse
1302013Tbbmd3_mtotal body bone mineral density 3 (mouse)Not determined2145196949179197085Mouse
12880427V25Dq3_mvitamin D inactive form serum level QTL 3 (mouse)2129341920163341920Mouse
13504830Bacsq1_mbaculum shape QTL 1 (mouse)2145716184161016184Mouse
12801456Intmrm1_mintima/media ratio modifier 1 (mouse)2142428347176428450Mouse
11049566Lmr28e_mleishmaniasis resistance 28e (mouse)2133144911167145058Mouse
12801461Intim1_mintima modifier 1 (mouse)2142428347176428450Mouse
11049567Lmr28f_mleishmaniasis resistance 28f (mouse)2133144911167145058Mouse
1301865Hdlq19_mHDL QTL 19 (mouse)Not determined2145518775179518926Mouse
12910520Scgq3_mspontaneous crescentic glomerulonephritis QTL 3 (mouse)2151709273174389124Mouse
1300846Pbwg11_mpostnatal body weight growth 11 (mouse)Not determined2138966600172966729Mouse

Markers in Region
Dnmt3b  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382153,718,228 - 153,718,302UniSTSGRCm38
GRCm382153,675,735 - 153,675,809UniSTSGRCm38
MGSCv372153,501,471 - 153,501,545UniSTSGRCm37
MGSCv372153,543,964 - 153,544,038UniSTSGRCm37
Celera2159,521,785 - 159,521,859UniSTS
Celera2159,562,053 - 159,562,127UniSTS
Cytogenetic Map2A2-A3UniSTS
Cytogenetic Map2H1UniSTS
cM Map2 UniSTS
Dnmt3b  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382153,677,240 - 153,677,617UniSTSGRCm38
MGSCv372153,502,976 - 153,503,353UniSTSGRCm37
Celera2159,523,287 - 159,523,664UniSTS
Cytogenetic Map2A2-A3UniSTS
Dnmt3b  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382153,670,887 - 153,672,295UniSTSGRCm38
MGSCv372153,496,623 - 153,498,031UniSTSGRCm37
Celera2159,516,937 - 159,518,345UniSTS
Cytogenetic Map2A2-A3UniSTS
Dnmt3b  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382153,726,484 - 153,727,302UniSTSGRCm38
GRCm382153,683,616 - 153,684,434UniSTSGRCm38
MGSCv372153,552,220 - 153,553,038UniSTSGRCm37
MGSCv372153,509,352 - 153,510,170UniSTSGRCm37
Celera2159,570,218 - 159,571,032UniSTS
Celera2159,529,911 - 159,530,727UniSTS
Cytogenetic Map2H1UniSTS
Cytogenetic Map2A2-A3UniSTS
Dnmt3b  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382153,677,198 - 153,677,591UniSTSGRCm38
MGSCv372153,502,934 - 153,503,327UniSTSGRCm37
Celera2159,523,245 - 159,523,638UniSTS
Cytogenetic Map2A2-A3UniSTS
Dnmt3b  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2A2-A3UniSTS
Dnmt3b  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2A2-A3UniSTS
cM Map2 UniSTS
Dnmt3b  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2A2-A3UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001003960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001003961 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001003963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001122997 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001271744 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001271745 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001271746 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001271747 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001417019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001417020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001417021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001417022 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001417023 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001417024 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_010068 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006498682 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006498683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006498684 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006498685 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006498686 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006498687 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006498688 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030247215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_374399 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF068626 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF068627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF068628 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF151969 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF151970 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF151971 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF151972 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF151973 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF151974 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF151975 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF151976 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL929021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AP003923 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AV469192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY078427 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC105677 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC105922 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ770921 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466551 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ067523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000056495   ⟹   ENSMUSP00000051830
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2153,491,374 - 153,529,646 (+)Ensembl
GRCm38.p6 Ensembl2153,649,454 - 153,687,726 (+)Ensembl
Ensembl Acc Id: ENSMUST00000072997   ⟹   ENSMUSP00000072761
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2153,491,370 - 153,529,650 (+)Ensembl
GRCm38.p6 Ensembl2153,649,450 - 153,687,730 (+)Ensembl
Ensembl Acc Id: ENSMUST00000081628   ⟹   ENSMUSP00000080334
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2153,491,373 - 153,529,650 (+)Ensembl
GRCm38.p6 Ensembl2153,649,453 - 153,687,730 (+)Ensembl
Ensembl Acc Id: ENSMUST00000088976   ⟹   ENSMUSP00000086370
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2153,491,374 - 153,529,650 (+)Ensembl
GRCm38.p6 Ensembl2153,649,454 - 153,687,730 (+)Ensembl
Ensembl Acc Id: ENSMUST00000103150   ⟹   ENSMUSP00000099439
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2153,491,374 - 153,529,650 (+)Ensembl
GRCm38.p6 Ensembl2153,649,454 - 153,687,730 (+)Ensembl
Ensembl Acc Id: ENSMUST00000103151   ⟹   ENSMUSP00000099440
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2153,491,373 - 153,529,650 (+)Ensembl
GRCm38.p6 Ensembl2153,649,453 - 153,687,730 (+)Ensembl
Ensembl Acc Id: ENSMUST00000109771   ⟹   ENSMUSP00000105393
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2153,491,537 - 153,529,236 (+)Ensembl
GRCm38.p6 Ensembl2153,649,617 - 153,687,316 (+)Ensembl
Ensembl Acc Id: ENSMUST00000109772   ⟹   ENSMUSP00000105394
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2153,491,374 - 153,529,650 (+)Ensembl
GRCm38.p6 Ensembl2153,649,454 - 153,687,730 (+)Ensembl
Ensembl Acc Id: ENSMUST00000109773   ⟹   ENSMUSP00000105395
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2153,491,370 - 153,529,650 (+)Ensembl
GRCm38.p6 Ensembl2153,649,450 - 153,687,730 (+)Ensembl
Ensembl Acc Id: ENSMUST00000109774   ⟹   ENSMUSP00000105396
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2153,491,373 - 153,529,650 (+)Ensembl
GRCm38.p6 Ensembl2153,649,453 - 153,687,730 (+)Ensembl
Ensembl Acc Id: ENSMUST00000132132
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2153,507,722 - 153,509,879 (+)Ensembl
GRCm38.p6 Ensembl2153,665,802 - 153,667,959 (+)Ensembl
Ensembl Acc Id: ENSMUST00000140811
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2153,511,290 - 153,512,336 (+)Ensembl
GRCm38.p6 Ensembl2153,669,370 - 153,670,416 (+)Ensembl
RefSeq Acc Id: NM_001003960   ⟹   NP_001003960
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392153,491,369 - 153,529,650 (+)NCBI
GRCm382153,649,449 - 153,687,730 (+)NCBI
MGSCv372153,475,190 - 153,513,466 (+)RGD
Celera2159,495,463 - 159,534,017 (+)NCBI
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001003961   ⟹   NP_001003961
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392153,491,369 - 153,529,650 (+)NCBI
GRCm382153,649,449 - 153,687,730 (+)NCBI
MGSCv372153,475,190 - 153,513,466 (+)RGD
Celera2159,495,463 - 159,534,017 (+)NCBI
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001003963   ⟹   NP_001003963
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392153,491,369 - 153,529,650 (+)NCBI
GRCm382153,649,449 - 153,687,730 (+)NCBI
MGSCv372153,475,190 - 153,513,466 (+)RGD
Celera2159,495,463 - 159,534,017 (+)NCBI
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001122997   ⟹   NP_001116469
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392153,491,369 - 153,529,650 (+)NCBI
GRCm382153,649,449 - 153,687,730 (+)NCBI
MGSCv372153,475,190 - 153,513,466 (+)RGD
Celera2159,495,463 - 159,534,017 (+)NCBI
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001271744   ⟹   NP_001258673
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392153,491,369 - 153,529,650 (+)NCBI
GRCm382153,649,449 - 153,687,730 (+)NCBI
Celera2159,495,463 - 159,534,017 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001271745   ⟹   NP_001258674
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392153,491,369 - 153,529,650 (+)NCBI
GRCm382153,649,449 - 153,687,730 (+)NCBI
Celera2159,495,463 - 159,534,017 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001271746   ⟹   NP_001258675
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392153,491,369 - 153,529,650 (+)NCBI
GRCm382153,649,449 - 153,687,730 (+)NCBI
Celera2159,495,463 - 159,534,017 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001271747   ⟹   NP_001258676
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392153,491,369 - 153,529,650 (+)NCBI
GRCm382153,649,449 - 153,687,730 (+)NCBI
Celera2159,495,463 - 159,534,017 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001417019   ⟹   NP_001403948
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392153,491,369 - 153,529,650 (+)NCBI
RefSeq Acc Id: NM_001417020   ⟹   NP_001403949
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392153,491,369 - 153,529,650 (+)NCBI
RefSeq Acc Id: NM_001417021   ⟹   NP_001403950
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392153,491,369 - 153,529,650 (+)NCBI
RefSeq Acc Id: NM_001417022   ⟹   NP_001403951
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392153,491,369 - 153,529,650 (+)NCBI
RefSeq Acc Id: NM_001417023   ⟹   NP_001403952
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392153,491,369 - 153,529,650 (+)NCBI
RefSeq Acc Id: NM_001417024   ⟹   NP_001403953
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392153,501,888 - 153,529,650 (+)NCBI
RefSeq Acc Id: NM_010068   ⟹   NP_034198
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392153,491,369 - 153,529,650 (+)NCBI
GRCm382153,649,449 - 153,687,730 (+)NCBI
MGSCv372153,475,190 - 153,513,466 (+)RGD
Celera2159,495,463 - 159,534,017 (+)NCBI
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006498682   ⟹   XP_006498745
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392153,501,766 - 153,529,650 (+)NCBI
GRCm382153,659,846 - 153,687,730 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006498683   ⟹   XP_006498746
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392153,501,766 - 153,529,650 (+)NCBI
GRCm382153,659,846 - 153,687,730 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006498684   ⟹   XP_006498747
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392153,491,332 - 153,529,650 (+)NCBI
GRCm382153,649,411 - 153,687,730 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006498685   ⟹   XP_006498748
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392153,501,766 - 153,529,650 (+)NCBI
GRCm382153,659,846 - 153,687,730 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006498686   ⟹   XP_006498749
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392153,501,766 - 153,529,650 (+)NCBI
GRCm382153,659,846 - 153,687,730 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006498687   ⟹   XP_006498750
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392153,501,766 - 153,529,650 (+)NCBI
GRCm382153,659,846 - 153,687,730 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006498688   ⟹   XP_006498751
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392153,501,766 - 153,529,650 (+)NCBI
GRCm382153,659,846 - 153,686,775 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030247215   ⟹   XP_030103075
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392153,502,682 - 153,529,650 (+)NCBI
GRCm382153,660,762 - 153,686,775 (+)NCBI
Sequence:
RefSeq Acc Id: XR_374399
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392153,501,766 - 153,529,650 (+)NCBI
GRCm382153,659,846 - 153,686,481 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001003960 (Get FASTA)   NCBI Sequence Viewer  
  NP_001003961 (Get FASTA)   NCBI Sequence Viewer  
  NP_001003963 (Get FASTA)   NCBI Sequence Viewer  
  NP_001116469 (Get FASTA)   NCBI Sequence Viewer  
  NP_001258673 (Get FASTA)   NCBI Sequence Viewer  
  NP_001258674 (Get FASTA)   NCBI Sequence Viewer  
  NP_001258675 (Get FASTA)   NCBI Sequence Viewer  
  NP_001258676 (Get FASTA)   NCBI Sequence Viewer  
  NP_001403948 (Get FASTA)   NCBI Sequence Viewer  
  NP_001403949 (Get FASTA)   NCBI Sequence Viewer  
  NP_001403950 (Get FASTA)   NCBI Sequence Viewer  
  NP_001403951 (Get FASTA)   NCBI Sequence Viewer  
  NP_001403952 (Get FASTA)   NCBI Sequence Viewer  
  NP_001403953 (Get FASTA)   NCBI Sequence Viewer  
  NP_034198 (Get FASTA)   NCBI Sequence Viewer  
  XP_006498745 (Get FASTA)   NCBI Sequence Viewer  
  XP_006498746 (Get FASTA)   NCBI Sequence Viewer  
  XP_006498747 (Get FASTA)   NCBI Sequence Viewer  
  XP_006498748 (Get FASTA)   NCBI Sequence Viewer  
  XP_006498749 (Get FASTA)   NCBI Sequence Viewer  
  XP_006498750 (Get FASTA)   NCBI Sequence Viewer  
  XP_006498751 (Get FASTA)   NCBI Sequence Viewer  
  XP_030103075 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC40178 (Get FASTA)   NCBI Sequence Viewer  
  AAC40179 (Get FASTA)   NCBI Sequence Viewer  
  AAC40180 (Get FASTA)   NCBI Sequence Viewer  
  AAF74515 (Get FASTA)   NCBI Sequence Viewer  
  AAF74516 (Get FASTA)   NCBI Sequence Viewer  
  AAF74517 (Get FASTA)   NCBI Sequence Viewer  
  AAF74518 (Get FASTA)   NCBI Sequence Viewer  
  AAF74519 (Get FASTA)   NCBI Sequence Viewer  
  AAF74520 (Get FASTA)   NCBI Sequence Viewer  
  AAF74521 (Get FASTA)   NCBI Sequence Viewer  
  AAF74522 (Get FASTA)   NCBI Sequence Viewer  
  AAI05678 (Get FASTA)   NCBI Sequence Viewer  
  AAI05923 (Get FASTA)   NCBI Sequence Viewer  
  AAL85481 (Get FASTA)   NCBI Sequence Viewer  
  EDL06032 (Get FASTA)   NCBI Sequence Viewer  
  EDL06033 (Get FASTA)   NCBI Sequence Viewer  
  EDL06034 (Get FASTA)   NCBI Sequence Viewer  
  EDL06035 (Get FASTA)   NCBI Sequence Viewer  
  EDL06036 (Get FASTA)   NCBI Sequence Viewer  
  EDL06037 (Get FASTA)   NCBI Sequence Viewer  
  EDL06038 (Get FASTA)   NCBI Sequence Viewer  
  EDL06039 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000051830
  ENSMUSP00000051830.8
  ENSMUSP00000072761
  ENSMUSP00000072761.4
  ENSMUSP00000080334
  ENSMUSP00000080334.7
  ENSMUSP00000086370
  ENSMUSP00000086370.6
  ENSMUSP00000099439
  ENSMUSP00000099439.4
  ENSMUSP00000099440
  ENSMUSP00000099440.2
  ENSMUSP00000105393
  ENSMUSP00000105393.2
  ENSMUSP00000105394
  ENSMUSP00000105394.2
  ENSMUSP00000105395
  ENSMUSP00000105395.2
  ENSMUSP00000105396
  ENSMUSP00000105396.3
GenBank Protein O88509 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001003961   ⟸   NM_001003961
- Peptide Label: isoform 1
- UniProtKB: O88510 (UniProtKB/Swiss-Prot),   O88511 (UniProtKB/Swiss-Prot),   O88509 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001003963   ⟸   NM_001003963
- Peptide Label: isoform 4
- UniProtKB: Q541E5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001003960   ⟸   NM_001003960
- Peptide Label: isoform 2
- UniProtKB: O88509 (UniProtKB/Swiss-Prot),   Q3KR45 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_034198   ⟸   NM_010068
- Peptide Label: isoform 3
- UniProtKB: O88509 (UniProtKB/Swiss-Prot),   Q3KR45 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001116469   ⟸   NM_001122997
- Peptide Label: isoform 5
- UniProtKB: Q3KR45 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001258673   ⟸   NM_001271744
- Peptide Label: isoform 1
- UniProtKB: O88510 (UniProtKB/Swiss-Prot),   O88511 (UniProtKB/Swiss-Prot),   O88509 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001258675   ⟸   NM_001271746
- Peptide Label: isoform 4
- UniProtKB: Q541E5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001258674   ⟸   NM_001271745
- Peptide Label: isoform 2
- UniProtKB: O88509 (UniProtKB/Swiss-Prot),   Q3KR45 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001258676   ⟸   NM_001271747
- Peptide Label: isoform 3
- UniProtKB: O88509 (UniProtKB/Swiss-Prot),   Q3KR45 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006498747   ⟸   XM_006498684
- Peptide Label: isoform X3
- UniProtKB: Q3KR45 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006498745   ⟸   XM_006498682
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006498746   ⟸   XM_006498683
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006498751   ⟸   XM_006498688
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_006498750   ⟸   XM_006498687
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_006498749   ⟸   XM_006498686
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_006498748   ⟸   XM_006498685
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_030103075   ⟸   XM_030247215
- Peptide Label: isoform X9
Ensembl Acc Id: ENSMUSP00000086370   ⟸   ENSMUST00000088976
Ensembl Acc Id: ENSMUSP00000072761   ⟸   ENSMUST00000072997
Ensembl Acc Id: ENSMUSP00000080334   ⟸   ENSMUST00000081628
Ensembl Acc Id: ENSMUSP00000051830   ⟸   ENSMUST00000056495
Ensembl Acc Id: ENSMUSP00000105395   ⟸   ENSMUST00000109773
Ensembl Acc Id: ENSMUSP00000105396   ⟸   ENSMUST00000109774
Ensembl Acc Id: ENSMUSP00000105393   ⟸   ENSMUST00000109771
Ensembl Acc Id: ENSMUSP00000105394   ⟸   ENSMUST00000109772
Ensembl Acc Id: ENSMUSP00000099440   ⟸   ENSMUST00000103151
Ensembl Acc Id: ENSMUSP00000099439   ⟸   ENSMUST00000103150
RefSeq Acc Id: NP_001403950   ⟸   NM_001417021
- Peptide Label: isoform 7
RefSeq Acc Id: NP_001403949   ⟸   NM_001417020
- Peptide Label: isoform 6
RefSeq Acc Id: NP_001403951   ⟸   NM_001417022
- Peptide Label: isoform 8
RefSeq Acc Id: NP_001403948   ⟸   NM_001417019
- Peptide Label: isoform 6
RefSeq Acc Id: NP_001403952   ⟸   NM_001417023
- Peptide Label: isoform 8
RefSeq Acc Id: NP_001403953   ⟸   NM_001417024
- Peptide Label: isoform 3
Protein Domains
ADD   PHD-type   PWWP   SAM-dependent MTase C5-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O88509-F1-model_v2 AlphaFold O88509 1-859 view protein structure

Promoters
RGD ID:6831186
Promoter ID:MM_KWN:32435
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_2Hour,   Brain,   ES_Cell,   Liver
Transcripts:ENSMUST00000056495,   ENSMUST00000072997,   ENSMUST00000103151,   ENSMUST00000109772,   ENSMUST00000109773,   NM_001003963,   NM_001122997,   NM_010068,   OTTMUST00000040726,   OTTMUST00000040805
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv362153,475,091 - 153,475,591 (+)MPROMDB
RGD ID:6879272
Promoter ID:EPDNEW_M3087
Type:initiation region
Name:Dnmt3b_1
Description:Mus musculus DNA methyltransferase 3B , transcript variant 9,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm382153,649,454 - 153,649,514EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1261819 AgrOrtholog
Ensembl Genes ENSMUSG00000027478 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000056495 ENTREZGENE
  ENSMUST00000056495.14 UniProtKB/TrEMBL
  ENSMUST00000072997 ENTREZGENE
  ENSMUST00000072997.10 UniProtKB/Swiss-Prot
  ENSMUST00000081628 ENTREZGENE
  ENSMUST00000081628.13 UniProtKB/Swiss-Prot
  ENSMUST00000088976 ENTREZGENE
  ENSMUST00000088976.12 UniProtKB/Swiss-Prot
  ENSMUST00000103150 ENTREZGENE
  ENSMUST00000103150.10 UniProtKB/Swiss-Prot
  ENSMUST00000103151 ENTREZGENE
  ENSMUST00000103151.8 UniProtKB/Swiss-Prot
  ENSMUST00000109771 ENTREZGENE
  ENSMUST00000109771.2 UniProtKB/TrEMBL
  ENSMUST00000109772 ENTREZGENE
  ENSMUST00000109772.8 UniProtKB/Swiss-Prot
  ENSMUST00000109773 ENTREZGENE
  ENSMUST00000109773.8 UniProtKB/Swiss-Prot
  ENSMUST00000109774 ENTREZGENE
  ENSMUST00000109774.9 UniProtKB/Swiss-Prot
Gene3D-CATH 2.30.30.140 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.150 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PWWP, helical domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro ADD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C5_DNA_meth_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C5_MeTfrase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNMT3_ADD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNMT3_ADD_PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNMT3B_ADD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PWWP_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM-dependent_MTases UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_FYVE_PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:13436 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1261819 ENTREZGENE
NCBI Gene 13436 ENTREZGENE
PANTHER DNA (CYTOSINE-5)-METHYLTRANSFERASE 3B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNA CYTOSINE-5- -METHYLTRANSFERASE 3-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam ADD_DNMT3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ADDz_Dnmt3b UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNA_methylase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PWWP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Dnmt3b PhenoGen
PROSITE ADD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C5_MTASE_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PWWP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM_MT_C5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART PWWP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF53335 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57903 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tudor/PWWP/MBT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt DNM3B_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  O88510 ENTREZGENE
  O88511 ENTREZGENE
  Q3KR45 ENTREZGENE, UniProtKB/TrEMBL
  Q541E5 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary O88510 UniProtKB/Swiss-Prot
  O88511 UniProtKB/Swiss-Prot