Rab27a (RAB27A, member RAS oncogene family) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Rab27a (RAB27A, member RAS oncogene family) Mus musculus
Analyze
Symbol: Rab27a
Name: RAB27A, member RAS oncogene family
RGD ID: 1551470
MGI Page MGI
Description: Enables GTP binding activity; GTPase activity; and myosin V binding activity. Acts upstream of or within several processes, including melanocyte differentiation; melanosome transport; and secretion by cell. Located in Golgi apparatus; cytoplasmic vesicle; and photoreceptor outer segment. Is expressed in 4-cell stage embryo; endocrine gland; lip; paravertebral ganglion; and thymus primordium. Used to study Hermansky-Pudlak syndrome 1; hemophagocytic lymphohistiocytosis; and platelet storage pool deficiency. Human ortholog(s) of this gene implicated in Griscelli syndrome type 2 and non-Langerhans-cell histiocytosis. Orthologous to human RAB27A (RAB27A, member RAS oncogene family).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: 2210402C08Rik; 2410003M20Rik; 4933437C11Rik; ash; ashen; ras-related protein Rab-27A
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39972,952,092 - 73,004,905 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl972,952,136 - 73,004,911 (+)EnsemblGRCm39 Ensembl
GRCm38973,044,810 - 73,097,623 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl973,044,854 - 73,097,629 (+)EnsemblGRCm38mm10GRCm38
MGSCv37972,892,672 - 72,945,399 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36972,841,997 - 72,894,724 (+)NCBIMGSCv36mm8
Celera970,231,031 - 70,283,807 (+)NCBICelera
Cytogenetic Map9DNCBI
cM Map940.08NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (EXP)
4-vinylcyclohexene dioxide  (EXP)
6-propyl-2-thiouracil  (ISO)
9-cis-retinoic acid  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (ISO)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
cadmium atom  (EXP)
cadmium dichloride  (EXP)
carbon nanotube  (EXP)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
dextran sulfate  (EXP)
dibutyl phthalate  (EXP)
diethyl maleate  (ISO)
diethylstilbestrol  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
entinostat  (ISO)
ethyl methanesulfonate  (ISO)
fulvestrant  (ISO)
gentamycin  (ISO)
irinotecan  (ISO)
isoprenaline  (EXP)
isotretinoin  (ISO)
ivermectin  (ISO)
leflunomide  (ISO)
lipopolysaccharide  (EXP)
maneb  (EXP)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (EXP)
nickel atom  (ISO)
paracetamol  (ISO)
paraquat  (EXP)
perfluorooctanoic acid  (ISO)
phenol red  (ISO)
potassium chromate  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (EXP,ISO)
sunitinib  (ISO)
T-2 toxin  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
testosterone enanthate  (ISO)
titanium dioxide  (EXP)
trimellitic anhydride  (EXP)
tungsten  (EXP)
valproic acid  (EXP,ISO)
vinclozolin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal blood coagulation  (IAGP)
abnormal bronchus epithelium morphology  (IAGP)
abnormal club cell morphology  (IAGP)
abnormal coat/hair pigmentation  (IAGP)
abnormal corticotroph morphology  (IAGP)
abnormal cytotoxic T cell physiology  (IAGP)
abnormal Harderian gland pigmentation  (IEA)
abnormal melanocyte morphology  (IEA)
abnormal melanosome transport  (IAGP)
abnormal neutrophil physiology  (IAGP)
abnormal NK cell degranulation  (IAGP)
abnormal platelet dense granule morphology  (IAGP)
abnormal platelet dense granule physiology  (IAGP)
abnormal pulmonary alveolar system morphology  (IAGP)
abnormal reproductive system physiology  (IAGP)
abnormal retina inner nuclear layer morphology  (IEA)
abnormal skin pigmentation  (IEA)
abnormal vesicle-mediated transport  (IAGP)
decreased body temperature  (IAGP)
decreased cytotoxic T cell cytolysis  (IAGP)
decreased erythrocyte cell number  (IAGP)
decreased leukocyte cell number  (IAGP)
decreased neutrophil cell number  (IAGP)
decreased NK cell degranulation  (IAGP)
decreased platelet ADP level  (IAGP)
decreased platelet aggregation  (IAGP)
decreased platelet ATP level  (IAGP)
decreased platelet dense granule number  (IAGP)
decreased platelet serotonin level  (IAGP)
diluted coat color  (IAGP)
hunched posture  (IAGP)
hypopigmentation  (IAGP)
impaired natural killer cell mediated cytotoxicity  (IAGP)
increased bleeding time  (IAGP)
increased circulating aspartate transaminase level  (IAGP)
increased circulating interferon-gamma level  (IAGP)
increased circulating interleukin-1 beta level  (IAGP)
increased circulating interleukin-6 level  (IAGP)
increased circulating lactate dehydrogenase level  (IAGP)
increased circulating tumor necrosis factor level  (IAGP)
increased cornea thickness  (IEA)
increased susceptibility to Riboviria infection  (IAGP)
lethargy  (IAGP)
limb grasping  (IEA)
pancytopenia  (IAGP)
thrombocytopenia  (IAGP)
weight loss  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Evidence that Griscelli syndrome with neurological involvement is caused by mutations in RAB27A, not MYO5A. Anikster Y, etal., Am J Hum Genet. 2002 Aug;71(2):407-14. Epub 2002 Jun 7.
2. Characterization of the molecular defects in Rab27a, caused by RAB27A missense mutations found in patients with Griscelli syndrome. Bahadoran P, etal., J Biol Chem. 2003 Mar 28;278(13):11386-92. Epub 2003 Jan 16.
3. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. Mouse MP Annotation Import Pipeline RGD automated import pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Mechanisms of biphasic insulin-granule exocytosis - roles of the cytoskeleton, small GTPases and SNARE proteins. Wang Z and Thurmond DC, J Cell Sci. 2009 Apr 1;122(Pt 7):893-903.
Additional References at PubMed
PMID:2379821   PMID:3410303   PMID:6322428   PMID:8889548   PMID:10349636   PMID:10512203   PMID:10859366   PMID:11042159   PMID:11076861   PMID:11178108   PMID:11228153   PMID:11256068  
PMID:11266470   PMID:11266472   PMID:11266473   PMID:11773082   PMID:11856727   PMID:11865063   PMID:11886590   PMID:11887186   PMID:11964381   PMID:11980908   PMID:12051743   PMID:12070017  
PMID:12122117   PMID:12189142   PMID:12401133   PMID:12477932   PMID:12578829   PMID:12590134   PMID:12907454   PMID:14610273   PMID:14617806   PMID:14722103   PMID:14724135   PMID:14730011  
PMID:14978221   PMID:15009730   PMID:15489334   PMID:15543135   PMID:15572405   PMID:15673612   PMID:15690086   PMID:15747579   PMID:15782199   PMID:15840001   PMID:15927964   PMID:16141072  
PMID:16141073   PMID:16602821   PMID:16923123   PMID:16923811   PMID:17062724   PMID:17090228   PMID:17339028   PMID:17351642   PMID:17384153   PMID:17587407   PMID:17698919   PMID:17761531  
PMID:18266782   PMID:18281284   PMID:18354201   PMID:18559336   PMID:18607085   PMID:18629000   PMID:18768935   PMID:18779337   PMID:18799693   PMID:18801842   PMID:18940603   PMID:18940604  
PMID:18991284   PMID:20028487   PMID:20049711   PMID:20138020   PMID:20362548   PMID:20813901   PMID:20877725   PMID:20939018   PMID:21045126   PMID:21148308   PMID:21160031   PMID:21170347  
PMID:21267068   PMID:21525430   PMID:21554507   PMID:21677130   PMID:21677750   PMID:21731673   PMID:21746860   PMID:21873635   PMID:22042600   PMID:22275436   PMID:22375060   PMID:22724066  
PMID:22767581   PMID:22865453   PMID:23115246   PMID:23160464   PMID:23281710   PMID:23403622   PMID:23460904   PMID:23671284   PMID:23716592   PMID:23986549   PMID:24284068   PMID:24584932  
PMID:25044020   PMID:25359237   PMID:25882854   PMID:25951179   PMID:26084661   PMID:26235199   PMID:26683831   PMID:26791531   PMID:26845357   PMID:26864340   PMID:27076615   PMID:27701149  
PMID:27702998   PMID:27733578   PMID:27927751   PMID:27991490   PMID:28043921   PMID:28100774   PMID:28589930   PMID:28716933   PMID:28954823   PMID:28978688   PMID:29045940   PMID:29059701  
PMID:29074498   PMID:29712939   PMID:30042153   PMID:30417443   PMID:30446775   PMID:30967557   PMID:32240120   PMID:32355248   PMID:32554809   PMID:32570938   PMID:32641688   PMID:32784729  
PMID:32815642   PMID:33095380   PMID:33562815   PMID:33799820   PMID:35701443   PMID:35770324   PMID:35870028   PMID:36214220   PMID:37166546   PMID:37641131   PMID:37860838  


Genomics

Comparative Map Data
Rab27a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39972,952,092 - 73,004,905 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl972,952,136 - 73,004,911 (+)EnsemblGRCm39 Ensembl
GRCm38973,044,810 - 73,097,623 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl973,044,854 - 73,097,629 (+)EnsemblGRCm38mm10GRCm38
MGSCv37972,892,672 - 72,945,399 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36972,841,997 - 72,894,724 (+)NCBIMGSCv36mm8
Celera970,231,031 - 70,283,807 (+)NCBICelera
Cytogenetic Map9DNCBI
cM Map940.08NCBI
RAB27A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381555,202,966 - 55,289,813 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1555,202,966 - 55,319,113 (-)EnsemblGRCh38hg38GRCh38
GRCh371555,495,164 - 55,582,011 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361553,283,084 - 53,369,293 (-)NCBINCBI36Build 36hg18NCBI36
Build 341553,283,093 - 53,349,877NCBI
Celera1532,384,380 - 32,470,592 (-)NCBICelera
Cytogenetic Map15q21.3NCBI
HuRef1532,320,428 - 32,407,649 (-)NCBIHuRef
CHM1_11555,613,105 - 55,700,081 (-)NCBICHM1_1
T2T-CHM13v2.01553,006,127 - 53,094,380 (-)NCBIT2T-CHM13v2.0
Rab27a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8882,663,373 - 82,717,267 (+)NCBIGRCr8
mRatBN7.2873,782,730 - 73,836,630 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl873,782,694 - 73,847,829 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx879,306,073 - 79,359,615 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0877,578,681 - 77,632,264 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0875,416,032 - 75,469,605 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0879,722,334 - 79,776,228 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl879,722,334 - 79,776,221 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0873,311,535 - 73,366,647 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4877,798,830 - 77,861,090 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1877,817,883 - 77,880,143 (+)NCBI
Celera867,919,443 - 67,972,735 (-)NCBICelera
Cytogenetic Map8q24NCBI
Rab27a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955409588,254 - 621,874 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955409588,725 - 621,874 (+)NCBIChiLan1.0ChiLan1.0
RAB27A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21644,469,463 - 44,561,427 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11548,650,359 - 48,737,460 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01534,174,491 - 34,263,045 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11552,498,202 - 52,584,731 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1552,498,202 - 52,529,984 (-)Ensemblpanpan1.1panPan2
RAB27A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13020,633,576 - 20,706,240 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3020,635,400 - 20,690,521 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3020,593,848 - 20,654,911 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03020,784,185 - 20,855,234 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3020,784,188 - 20,855,192 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13020,722,265 - 20,783,357 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03020,812,483 - 20,867,409 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03020,943,977 - 20,999,165 (-)NCBIUU_Cfam_GSD_1.0
Rab27a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864098,890,138 - 98,967,479 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647116,738,230 - 16,815,943 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647116,738,204 - 16,815,561 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAB27A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1116,532,974 - 116,606,474 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11116,532,816 - 116,606,477 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21129,070,103 - 129,144,161 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RAB27A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12628,140,972 - 28,227,847 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2628,197,464 - 28,227,963 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048113,038,948 - 113,126,658 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rab27a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247316,319,092 - 6,355,534 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247316,315,064 - 6,355,431 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rab27a
1586 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1430
Count of miRNA genes:603
Interacting mature miRNAs:718
Transcripts:ENSMUST00000034722, ENSMUST00000184032, ENSMUST00000184146, ENSMUST00000184575
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1558872Ibdq1_minflammatory bowel disease QTL 1 (mouse)Not determined93397884073439255Mouse
4142042Alpq3_malcohol preference QTL 3 (mouse)Not determined93730619798701707Mouse
12738449Spcq2_msperm count QTL 2 (mouse)93939988573399885Mouse
4141071Ath29_matherosclerosis 29 (mouse)Not determined94041959474607925Mouse
1301702Brm1_mbrachyury modifier 1 (mouse)Not determined94080504774805204Mouse
1301558Stheal8_msoft tissue heal 8 (mouse)Not determined94348071477480860Mouse
10045639Heal28_mwound healing/regeneration 28 (mouse)Not determined94348071477480860Mouse
1301435Trigq1_mtriglyceride QTL 1 (mouse)Not determined94442817478428262Mouse
1300563Pgia5_mproteoglycan induced arthritis 5 (mouse)Not determined94883105682831177Mouse
1300716Cd4ts4_mCD4 T cell subset 4 (mouse)Not determined94883105682831177Mouse
4141224Dxmod_mdoxorubicin nephropathy modifier (mouse)Not determined49452421101406120Mouse
14746993Manh66_mmandible shape 66 (mouse)94981404883814048Mouse
1301184Bdln4_mbody length 4 (mouse)Not determined95015132084151448Mouse
1301241Renf1_mrenal failure 1 (mouse)Not determined95203447899792481Mouse
12790990Tgl7_mtriglyceride 7 (mouse)95455996088559960Mouse
10043877Adip21_madiposity 21 (mouse)Not determined95643910890439255Mouse
4141676Neogq1_mneonatal growth QTL 1 (mouse)Not determined95780504786121973Mouse
1301803Stheal9_msoft tissue heal 9 (mouse)Not determined95902438793024534Mouse
1301172Fembrs6_mfemur breaking strength 6 (mouse)Not determined95902438793024534Mouse
1301456Adip5_madiposity 5 (mouse)Not determined95936994693370128Mouse
1300848Skull13_mskull morphology 13 (mouse)Not determined95936994693370128Mouse
5491195Mobq8_mmultigenic obesity QTL 8 (mouse)Not determined95936994693370128Mouse
13207569Tcq13_mtotal cholesterol QTL 13 (mouse)959897283109089068Mouse
1301611Lrnx3_mlearning contextual 3 (mouse)Not determined96214976796149881Mouse
4141833W10q13_mweight 10 weeks QTL 13 (mouse)Not determined63239711120191934Mouse
4141545Tailaq2_mtail length adjusted QTL 2 (mouse)Not determined63239711120191934Mouse
1357635Splq4_mspleen weight QTL 4 (mouse)Not determined963239711120191934Mouse
11081165Psl6_mpromotion susceptibility QTL 6 (mouse)96504119195522808Mouse
1301290Smgd1_msubmucosal gland distribution 1 (mouse)Not determined96583105686577967Mouse
1301636Lith5_mlithogenic gene 5 (mouse)Not determined966089077100089175Mouse
10045638Heal29_mwound healing/regeneration 29 (mouse)Not determined967006220101006220Mouse
1357610Vtbt8_mvertebral trabecular bone trait 8 (mouse)Not determined968779563102779705Mouse
1301924Bmd10_mbone mineral density 10 (mouse)Not determined968779563102779705Mouse
1301302Pas4_mpulmonary adenoma susceptibility 4 (mouse)Not determined969121898103121973Mouse
10412174Habiir4_mhyperoxic acute lung injury imprinted region 4 (mouse)Not determined96926774798701707Mouse
1301621Hpic1_mhaloperidol-induced catalepsy 1 (mouse)Not determined969428566103428698Mouse
1301573Etohcta8_methanol conditioned taste aversion 8 (mouse)Not determined972859058106859205Mouse
10054068El8_mepilepsy 8 (mouse)Not determined972859058106859205Mouse


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001301230 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001301232 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_023635 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006510780 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB046693 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB120511 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB232622 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC157513 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC158997 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF304376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK008798 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK010373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK017093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK030529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK165298 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK182897 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK191483 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK198653 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK203572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK207170 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK208837 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK209383 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK210007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK219379 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB857060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC008173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC009656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE948607 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP769437 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY151058 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466522 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ077071 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CV784419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000034722   ⟹   ENSMUSP00000034722
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl972,952,139 - 73,004,874 (+)Ensembl
GRCm38.p6 Ensembl973,044,857 - 73,097,592 (+)Ensembl
RefSeq Acc Id: ENSMUST00000184032
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl973,002,115 - 73,003,697 (+)Ensembl
GRCm38.p6 Ensembl973,094,833 - 73,096,415 (+)Ensembl
RefSeq Acc Id: ENSMUST00000184146   ⟹   ENSMUSP00000139310
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl972,952,136 - 73,004,911 (+)Ensembl
GRCm38.p6 Ensembl973,044,854 - 73,097,629 (+)Ensembl
RefSeq Acc Id: ENSMUST00000184575
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl972,952,266 - 72,992,602 (+)Ensembl
GRCm38.p6 Ensembl973,044,984 - 73,085,320 (+)Ensembl
RefSeq Acc Id: NM_001301230   ⟹   NP_001288159
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39972,952,092 - 73,004,896 (+)NCBI
GRCm38973,044,810 - 73,097,614 (+)NCBI
Celera970,230,976 - 70,283,828 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001301232   ⟹   NP_001288161
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39972,971,430 - 73,004,896 (+)NCBI
GRCm38973,064,148 - 73,097,614 (+)NCBI
Celera970,230,976 - 70,283,828 (+)NCBI
Sequence:
RefSeq Acc Id: NM_023635   ⟹   NP_076124
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39972,952,092 - 73,004,896 (+)NCBI
GRCm38973,044,810 - 73,097,614 (+)NCBI
MGSCv37972,892,672 - 72,945,399 (+)RGD
Celera970,230,976 - 70,283,828 (+)NCBI
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006510780   ⟹   XP_006510843
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39972,972,708 - 73,004,905 (+)NCBI
GRCm38973,064,454 - 73,097,623 (+)NCBI
Sequence:
RefSeq Acc Id: NP_076124   ⟸   NM_023635
- UniProtKB: Q9ERI2 (UniProtKB/Swiss-Prot),   Q544U7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006510843   ⟸   XM_006510780
- Peptide Label: isoform X1
- UniProtKB: Q9ERI2 (UniProtKB/Swiss-Prot),   Q544U7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001288159   ⟸   NM_001301230
- UniProtKB: Q9ERI2 (UniProtKB/Swiss-Prot),   Q544U7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001288161   ⟸   NM_001301232
- UniProtKB: Q9ERI2 (UniProtKB/Swiss-Prot),   Q544U7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000139310   ⟸   ENSMUST00000184146
RefSeq Acc Id: ENSMUSP00000034722   ⟸   ENSMUST00000034722

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9ERI2-F1-model_v2 AlphaFold Q9ERI2 1-221 view protein structure

Promoters
RGD ID:6845012
Promoter ID:MM_KWN:58050
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_023635,   UC009QQW.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36972,891,871 - 72,892,822 (+)MPROMDB
RGD ID:6848458
Promoter ID:MM_ACW:51246
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:ES_Cell
Transcripts:RAB27A.ESEP07-UNSPLICED
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36972,942,976 - 72,943,476 (+)MPROMDB
RGD ID:8670164
Promoter ID:EPDNEW_M13112
Type:initiation region
Name:Rab27a_1
Description:Mus musculus RAB27A, member RAS oncogene family , transcriptvariant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38973,044,840 - 73,044,900EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1861441 AgrOrtholog
Ensembl Genes ENSMUSG00000032202 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000034722 ENTREZGENE
  ENSMUST00000034722.5 UniProtKB/Swiss-Prot
  ENSMUST00000184146 ENTREZGENE
  ENSMUST00000184146.8 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rab27a/b UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Small_GTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:11891 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1861441 ENTREZGENE
NCBI Gene 11891 ENTREZGENE
PANTHER RAS-RELATED PROTEIN RAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAS-RELATED PROTEIN RAB-27A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ras UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rab27a PhenoGen
PRINTS RASTRNSFRMNG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE RAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
SMART RAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RHO UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt Q544U7 ENTREZGENE, UniProtKB/TrEMBL
  Q9ERI2 ENTREZGENE, UniProtKB/Swiss-Prot