Nsun2 (NOL1/NOP2/Sun domain family member 2) - Rat Genome Database

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Gene: Nsun2 (NOL1/NOP2/Sun domain family member 2) Mus musculus
Analyze
Symbol: Nsun2
Name: NOL1/NOP2/Sun domain family member 2
RGD ID: 1551238
MGI Page MGI
Description: Enables mRNA (cytidine-5-)-methyltransferase activity and tRNA (cytidine-5-)-methyltransferase activity. Involved in several processes, including hair follicle maturation; meiotic cell cycle checkpoint signaling; and tRNA stabilization. Acts upstream of or within in utero embryonic development. Located in chromatoid body. Is expressed in several structures, including branchial arch; cardiovascular system; central nervous system; extraembryonic component; and sensory organ. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 5. Orthologous to human NSUN2 (NOP2/Sun RNA methyltransferase 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: D13Wsu123e; Mi; Misu; mRNA cytosine C(5)-methyltransferase; Myc-induced SUN domain containing protein; myc-induced SUN domain-containing protein; NOL1/NOP2/Sun domain family 2; RNA cytosine C(5)-methyltransferase NSUN2; tRNA (cytosine(34)-C(5))-methyltransferase; tRNA (cytosine-5-)-methyltransferase NSUN2; tRNA cytosine C(5)-methyltransferase
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391369,760,135 - 69,783,899 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1369,681,865 - 69,783,899 (+)EnsemblGRCm39 Ensembl
GRCm381369,612,016 - 69,635,780 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1369,533,746 - 69,635,780 (+)EnsemblGRCm38mm10GRCm38
MGSCv371369,750,895 - 69,774,658 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361370,079,616 - 70,103,029 (+)NCBIMGSCv36mm8
Celera1371,956,753 - 71,980,601 (+)NCBICelera
Cytogenetic Map13B3NCBI
cM Map1335.55NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,6-dinitrotoluene  (ISO)
3-chloropropane-1,2-diol  (ISO)
4,4'-sulfonyldiphenol  (ISO)
all-trans-retinoic acid  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (ISO)
Bisphenol A diglycidyl ether  (EXP)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (EXP)
CGP 52608  (ISO)
chloropicrin  (ISO)
chromium(6+)  (EXP)
clofibrate  (EXP)
copper(II) sulfate  (ISO)
coumarin  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (ISO)
Dibutyl phosphate  (ISO)
dioxygen  (EXP)
doxorubicin  (ISO)
enzyme inhibitor  (ISO)
epoxiconazole  (EXP)
ethyl methanesulfonate  (ISO)
flutamide  (ISO)
FR900359  (ISO)
hydrogen peroxide  (ISO)
ivermectin  (ISO)
lead(0)  (ISO)
menadione  (ISO)
methidathion  (EXP)
methyl methanesulfonate  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nefazodone  (ISO)
nimesulide  (ISO)
paraquat  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
potassium chromate  (ISO)
potassium dichromate  (EXP)
resveratrol  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (ISO)
sunitinib  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
trimellitic anhydride  (EXP)
triphenyl phosphate  (ISO)
valproic acid  (ISO)
venlafaxine hydrochloride  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal coat appearance  (IAGP)
abnormal cornea morphology  (IAGP)
abnormal cranium morphology  (IAGP)
abnormal deltoid tuberosity morphology  (IAGP)
abnormal dorsal root ganglion morphology  (IEA)
abnormal ductus venosus valve morphology  (IEA)
abnormal epidermis stratum basale morphology  (IAGP)
abnormal external carotid artery origin  (IEA)
abnormal eye muscle morphology  (IEA)
abnormal fertility/fecundity  (IAGP)
abnormal forebrain morphology  (IEA)
abnormal hair cycle  (IAGP)
abnormal hair cycle anagen phase  (IAGP)
abnormal hair shedding  (IAGP)
abnormal humerus morphology  (IAGP)
abnormal hypoglossal nerve topology  (IEA)
abnormal infrahyoid muscle connection  (IEA)
abnormal joint morphology  (IAGP)
abnormal lens morphology  (IAGP)
abnormal liver physiology  (IAGP)
abnormal optic chiasm morphology  (IEA)
abnormal optic cup morphology  (IEA)
abnormal optic stalk morphology  (IEA)
abnormal rib morphology  (IEA)
abnormal snout morphology  (IAGP)
abnormal spine curvature  (IAGP)
abnormal systemic artery morphology  (IEA)
abnormal testis morphology  (IEA)
abnormal thymus capsule morphology  (IEA)
abnormal tooth morphology  (IAGP)
abnormal vertebral artery topology  (IEA)
absent ductus venosus valve  (IEA)
absent hypoglossal canal  (IEA)
absent hypoglossal nerve  (IEA)
absent segment of posterior cerebral artery  (IEA)
absent stapedial artery  (IEA)
alopecia  (IAGP)
basisphenoid bone foramen  (IEA)
cataract  (IAGP)
decreased body length  (IAGP)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased bone mineral content  (IAGP)
decreased bone mineral density  (IAGP)
decreased circulating amylase level  (IAGP)
decreased circulating cholesterol level  (IAGP)
decreased circulating free fatty acids level  (IAGP)
decreased circulating glucose level  (IAGP)
decreased circulating glycerol level  (IAGP)
decreased circulating HDL cholesterol level  (IAGP)
decreased circulating LDL cholesterol level  (IAGP)
decreased energy expenditure  (IAGP)
decreased grip strength  (IAGP)
decreased lean body mass  (IAGP)
decreased length of long bones  (IAGP)
decreased mean corpuscular hemoglobin  (IAGP)
decreased mean corpuscular volume  (IAGP)
decreased percent body fat/body weight  (IAGP)
decreased total body fat amount  (IAGP)
disheveled coat  (IAGP)
ductus venosus stenosis  (IEA)
excessive tearing  (IEA)
fusion of vertebral arches  (IEA)
hyperactivity  (IAGP)
improved glucose tolerance  (IAGP)
increased carbon dioxide production  (IAGP)
increased energy expenditure  (IAGP)
increased erythrocyte cell number  (IAGP)
increased oxygen consumption  (IAGP)
increased trigeminal neuroma incidence  (IEA)
intraembryonal intestine elongation  (IEA)
kyphosis  (IAGP)
lethality, incomplete penetrance  (IAGP)
lordosis  (IAGP)
male infertility  (IAGP)
oligozoospermia  (IAGP)
persistent dorsal ophthalmic artery  (IEA)
persistent trigeminal artery  (IEA)
preweaning lethality, incomplete penetrance  (IAGP)
reduced sympathetic cervical ganglion size  (IEA)
retroesophageal right subclavian artery  (IEA)
small superior cervical ganglion  (IEA)
subcutaneous edema  (IEA)
testis degeneration  (IAGP)
thin hypoglossal nerve  (IEA)
thin motoric part of trigeminal nerve  (IEA)
thoracoschisis  (IEA)
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Ko MS, etal., Hum Mol Genet 1998 Nov;7(12):1967-78.
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Database resources of the National Center for Biotechnology Information. Wheeler DL, etal., Nucleic Acids Res 2001 Jan 1;29(1):11-6.
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10725249   PMID:10922068   PMID:11042159   PMID:11076861   PMID:12477932   PMID:12904583   PMID:14610273   PMID:15782199   PMID:16141072   PMID:16141073  
PMID:16713953   PMID:18799693   PMID:19596847   PMID:21267068   PMID:21589869   PMID:21677750   PMID:21873635   PMID:22144916   PMID:22541562   PMID:22885326   PMID:23401851   PMID:23816522  
PMID:23871666   PMID:24457600   PMID:24652767   PMID:24721909   PMID:25063673   PMID:25340873   PMID:26336360   PMID:26764384   PMID:27306184   PMID:27899360   PMID:27996060   PMID:28041877  
PMID:28378742   PMID:29539633   PMID:30973865   PMID:31199786   PMID:31235931   PMID:31276587   PMID:31287866   PMID:32325033   PMID:32332707   PMID:32734582   PMID:34140513   PMID:34345012  
PMID:34389722   PMID:34494549   PMID:34954053   PMID:36114006   PMID:36357715   PMID:36748584   PMID:36792629   PMID:37037818   PMID:38048324   PMID:38355793   PMID:38468490   PMID:38822427  


Genomics

Comparative Map Data
Nsun2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391369,760,135 - 69,783,899 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1369,681,865 - 69,783,899 (+)EnsemblGRCm39 Ensembl
GRCm381369,612,016 - 69,635,780 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1369,533,746 - 69,635,780 (+)EnsemblGRCm38mm10GRCm38
MGSCv371369,750,895 - 69,774,658 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361370,079,616 - 70,103,029 (+)NCBIMGSCv36mm8
Celera1371,956,753 - 71,980,601 (+)NCBICelera
Cytogenetic Map13B3NCBI
cM Map1335.55NCBI
NSUN2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3856,599,239 - 6,633,044 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl56,599,239 - 6,633,291 (-)EnsemblGRCh38hg38GRCh38
GRCh3756,599,352 - 6,633,157 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3656,652,352 - 6,686,157 (-)NCBINCBI36Build 36hg18NCBI36
Build 3456,652,352 - 6,686,157NCBI
Celera56,626,418 - 6,660,533 (-)NCBICelera
Cytogenetic Map5p15.31NCBI
HuRef56,573,722 - 6,608,099 (-)NCBIHuRef
CHM1_156,599,051 - 6,633,433 (-)NCBICHM1_1
T2T-CHM13v2.056,529,664 - 6,563,719 (-)NCBIT2T-CHM13v2.0
Nsun2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8135,490,583 - 35,514,839 (-)NCBIGRCr8
mRatBN7.2133,662,139 - 33,685,887 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl133,662,139 - 33,685,862 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx133,491,491 - 33,515,193 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0139,490,097 - 39,513,799 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0133,690,317 - 33,714,040 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0136,295,650 - 36,319,906 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl136,295,650 - 36,319,966 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0137,692,672 - 37,716,930 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4173,820,859 - 3,844,582 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1173,822,627 - 3,844,539 (-)NCBI
Celera132,266,227 - 32,289,950 (-)NCBICelera
Cytogenetic Map1p11NCBI
Nsun2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555044,338,855 - 4,361,520 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555044,339,044 - 4,360,176 (-)NCBIChiLan1.0ChiLan1.0
NSUN2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v246,848,107 - 6,880,920 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan155,001,714 - 5,034,493 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v056,921,073 - 6,953,622 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.156,596,414 - 6,629,121 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl56,596,414 - 6,629,121 (-)Ensemblpanpan1.1panPan2
NSUN2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1347,145,176 - 7,172,761 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl347,144,586 - 7,172,335 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3411,653,467 - 11,681,035 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0347,053,243 - 7,080,793 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl347,052,661 - 7,080,668 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1347,100,392 - 7,127,969 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0347,080,917 - 7,108,473 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0347,295,959 - 7,323,555 (+)NCBIUU_Cfam_GSD_1.0
Nsun2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213240,207,658 - 240,234,194 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936634799,176 - 826,852 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936634798,894 - 825,413 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NSUN2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1675,335,047 - 75,367,180 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11675,335,565 - 75,414,659 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21681,695,118 - 81,761,793 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NSUN2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.146,279,984 - 6,312,737 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl46,280,001 - 6,312,569 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606422,406,642 - 22,439,412 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nsun2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247514,287,249 - 4,309,438 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247514,288,436 - 4,309,172 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Nsun2
1146 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1487
Count of miRNA genes:689
Interacting mature miRNAs:869
Transcripts:ENSMUST00000022087, ENSMUST00000109699, ENSMUST00000127854, ENSMUST00000136891, ENSMUST00000136932, ENSMUST00000143716, ENSMUST00000148115, ENSMUST00000176485
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300561Heal7_mwound healing/regeneration 7 (mouse)Not determined133614482070144904Mouse
4142331Bxs6_mBXSB/MpJ autoimmune nephritis 6 (mouse)Not determined4521044283744746Mouse
4142009Pregq3_mpregnancy QTL 3 (mouse)Not determined132061551272385189Mouse
1357587Pfat3_mpredicted fat percentage 3 (mouse)Not determined133610153070101640Mouse
1301593Heal8_mwound healing/regeneration 8 (mouse)Not determined1368053999102054119Mouse
1300573Elsgp2_melevated serum gp70 2 (mouse)Not determined135061682884617027Mouse
10412109Bxs7_mBXSB/MpJ autoimmune nephritis 7 (mouse)Not determined134521044283744746Mouse
1558850Sgp3_mserum gp70 production 3 (mouse)Not determined135647045676971314Mouse
4142314Tailaq3_mtail length adjusted QTL 3 (mouse)Not determined55720354112431103Mouse
10412235Scgq5_mspontaneous crescentic glomerulonephritis QTL 5 (mouse)Not determined133606090896239162Mouse
1301445Listr2_mlisteriosis resistance 2 (mouse)Not determined1366744601100744746Mouse
4141992W6q16_mweight 6 weeks QTL 16 (mouse)Not determined55720354112431103Mouse
4142372Moo2_mmodifier of Odc2 (mouse)Not determinedX5031841184318559Mouse
15039353Nmrs35_mNAFLD-associated magnetic resonance shift 35 (mouse)134058825374588253Mouse
10412163Wra1_mwheel running activity 1 (mouse)Not determined135913260093132738Mouse
1300941Skl6_mskeletal size (tail length) 6 (mouse)Not determined136425082198250945Mouse
1302157Bwem2_mbody weight day 30 males 2 (mouse)Not determined133962924973629397Mouse
4142241Tailq3_mtail length QTL 3 (mouse)Not determined55720354112431103Mouse
4140959W10q17_mweight 10 weeks QTL 17 (mouse)Not determined55720354112431103Mouse
1357553Cia28_mcollagen induced arthritis 28 (mouse)Not determined135662924996239162Mouse
1302073Pgct1_mprimordial germ cell tumor locus 1 (mouse)Not determined135382078387820897Mouse
1300985Bmd13_mbone mineral density 13 (mouse)Not determined133962924973629397Mouse
1300862Cfbw5_mcystic fibrosis body weight 5 (mouse)Not determined133872035872720517Mouse
1301949Skull20_mskull morphology 20 (mouse)Not determined136425082198250945Mouse
1357563Bmch6_mbone mechanical trait 6 (mouse)Not determined135538498089385140Mouse
1300668Pas10_mpulmonary adenoma susceptibility 10 (mouse)Not determined134148904275489158Mouse
10402414Sgp5_mserum gp70 production 5 (mouse)Not determined1356470456105422186Mouse
1301666Eae13_msusceptibility to experimental allergic encephalomyelitis 13 (mouse)Not determined135031841184318559Mouse
26884393Humsd7_mhumerus midshaft diameter 7, 16 week (mouse)13395000076048119Mouse
1301734Acsns2_mAngiostrongylus costaricensis nematode susceptibility 2 (mouse)Not determined133610153070101640Mouse
26884396Humsd4_mhumerus midshaft diameter 4, 10 week (mouse)134785347673148119Mouse
14696726Kidrq3_mkidney weight, right QTL 3 (mouse)1368217066102217066Mouse
1301801Cpfd5_mcerebellum pattern fissures (mouse)Not determined133962924973629397Mouse
4142147Mvwf4_mmodifier of von Willebrand factor 4 (mouse)Not determined20477612112898424Mouse
14746975Manh74_mmandible shape 74 (mouse)135247726986477269Mouse

Markers in Region
AI463178  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381369,634,142 - 69,634,270UniSTSGRCm38
MGSCv371369,773,020 - 69,773,148UniSTSGRCm37
Celera1371,978,963 - 71,979,091UniSTS
Cytogenetic Map13C1UniSTS
cM Map1340.0UniSTS
Whitehead/MRC_RH13655.98UniSTS
RH125669  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381369,634,070 - 69,634,319UniSTSGRCm38
MGSCv371369,772,948 - 69,773,197UniSTSGRCm37
Celera1371,978,891 - 71,979,140UniSTS
Cytogenetic Map13C1UniSTS
cM Map1340.0UniSTS
Whitehead/MRC_RH13661.0UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_145354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC122484 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI787627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK008568 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK030124 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK075999 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK150631 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151917 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK154789 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171399 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK186941 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK188384 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK191741 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK192164 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK192852 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK194164 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK196657 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK197440 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK197911 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK200198 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK202255 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK203382 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205395 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK206159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK206316 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK207012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK208749 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK210798 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK211038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK215502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK215620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC013625 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC023735 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC025549 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX630130 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466563 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ092700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ490066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY499682 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000022087   ⟹   ENSMUSP00000022087
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1369,760,363 - 69,783,899 (+)Ensembl
GRCm38.p6 Ensembl1369,612,244 - 69,635,780 (+)Ensembl
Ensembl Acc Id: ENSMUST00000109699   ⟹   ENSMUSP00000105321
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1369,760,135 - 69,782,453 (+)Ensembl
GRCm38.p6 Ensembl1369,612,016 - 69,634,334 (+)Ensembl
Ensembl Acc Id: ENSMUST00000127854
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1369,760,722 - 69,767,712 (+)Ensembl
GRCm38.p6 Ensembl1369,612,603 - 69,619,593 (+)Ensembl
Ensembl Acc Id: ENSMUST00000136891
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1369,778,859 - 69,779,787 (+)Ensembl
GRCm38.p6 Ensembl1369,630,740 - 69,631,668 (+)Ensembl
Ensembl Acc Id: ENSMUST00000136932
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1369,769,430 - 69,777,748 (+)Ensembl
GRCm38.p6 Ensembl1369,621,311 - 69,629,629 (+)Ensembl
Ensembl Acc Id: ENSMUST00000143716   ⟹   ENSMUSP00000134962
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1369,681,865 - 69,763,587 (+)Ensembl
GRCm38.p6 Ensembl1369,533,746 - 69,615,468 (+)Ensembl
Ensembl Acc Id: ENSMUST00000148115
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1369,681,887 - 69,754,060 (+)Ensembl
GRCm38.p6 Ensembl1369,533,768 - 69,605,941 (+)Ensembl
Ensembl Acc Id: ENSMUST00000176485   ⟹   ENSMUSP00000135455
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1369,760,168 - 69,782,165 (+)Ensembl
GRCm38.p6 Ensembl1369,612,049 - 69,634,046 (+)Ensembl
RefSeq Acc Id: NM_145354   ⟹   NP_663329
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391369,760,135 - 69,783,899 (+)NCBI
GRCm381369,612,016 - 69,635,780 (+)NCBI
MGSCv371369,750,895 - 69,774,658 (+)RGD
Celera1371,956,752 - 71,980,601 (+)NCBI
cM Map13 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_663329   ⟸   NM_145354
- UniProtKB: Q8CDF9 (UniProtKB/Swiss-Prot),   Q8BPG9 (UniProtKB/Swiss-Prot),   Q3U972 (UniProtKB/Swiss-Prot),   A0PJD6 (UniProtKB/Swiss-Prot),   Q91YX9 (UniProtKB/Swiss-Prot),   Q1HFZ0 (UniProtKB/Swiss-Prot),   A0A1S6GWH4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000134962   ⟸   ENSMUST00000143716
Ensembl Acc Id: ENSMUSP00000022087   ⟸   ENSMUST00000022087
Ensembl Acc Id: ENSMUSP00000105321   ⟸   ENSMUST00000109699
Ensembl Acc Id: ENSMUSP00000135455   ⟸   ENSMUST00000176485
Protein Domains
SAM-dependent MTase RsmB/NOP-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q1HFZ0-F1-model_v2 AlphaFold Q1HFZ0 1-757 view protein structure

Promoters
RGD ID:8680768
Promoter ID:EPDNEW_M18415
Type:initiation region
Name:Nsun2_1
Description:Mus musculus NOL1/NOP2/Sun domain family member 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381369,612,022 - 69,612,082EPDNEW
RGD ID:6824205
Promoter ID:MM_KWN:14618
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day2,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   ES_Cell,   Liver
Transcripts:OTTMUST00000060367,   OTTMUST00000060368,   UC007RCM.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361369,750,766 - 69,751,266 (+)MPROMDB
RGD ID:6824203
Promoter ID:MM_KWN:14620
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:OTTMUST00000060372
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361369,768,676 - 69,769,176 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:107252 AgrOrtholog
Ensembl Genes ENSMUSG00000021595 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000022087.7 UniProtKB/Swiss-Prot
  ENSMUST00000109699 ENTREZGENE
  ENSMUST00000109699.11 UniProtKB/Swiss-Prot
  ENSMUST00000143716.8 UniProtKB/TrEMBL
  ENSMUST00000176485.8 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.150 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro MeTrfase_RsmB-F_NOP2_cat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MeTrfase_RsmB/NOP2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RCMT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RCMT_NCL1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM-dependent_MTases UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:28114 UniProtKB/Swiss-Prot
MGD MGI:107252 ENTREZGENE
NCBI Gene 28114 ENTREZGENE
PANTHER PTHR22808 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RNA CYTOSINE C(5)-METHYLTRANSFERASE NSUN2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Methyltr_RsmB-F UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Nsun2 PhenoGen
PRINTS RCMTFAMILY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RCMTNCL1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE SAM_MT_RSMB_NOP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF53335 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A1S6GWH4 ENTREZGENE, UniProtKB/TrEMBL
  A0PJD6 ENTREZGENE
  H3BJF3_MOUSE UniProtKB/TrEMBL
  H3BKN0_MOUSE UniProtKB/TrEMBL
  NSUN2_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3U972 ENTREZGENE
  Q8BPG9 ENTREZGENE
  Q8CDF9 ENTREZGENE
  Q91YX9 ENTREZGENE
UniProt Secondary A0PJD6 UniProtKB/Swiss-Prot
  Q3U972 UniProtKB/Swiss-Prot
  Q8BPG9 UniProtKB/Swiss-Prot
  Q8CDF9 UniProtKB/Swiss-Prot
  Q91YX9 UniProtKB/Swiss-Prot