Steap3 (STEAP family member 3) - Rat Genome Database

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Gene: Steap3 (STEAP family member 3) Mus musculus
Analyze
Symbol: Steap3
Name: STEAP family member 3
RGD ID: 1551194
MGI Page MGI
Description: Enables cupric reductase (NADH) activity and ferric-chelate reductase (NADPH) activity. Acts upstream of or within exosomal secretion; positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; and transition metal ion transport. Located in endosome membrane and plasma membrane. Is expressed in several structures, including bone; genitourinary system; liver; nervous system; and white fat. Orthologous to human STEAP3 (STEAP3 metalloreductase).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1010001D01Rik; dudulin 2; dudulin-2; metalloreductase STEAP3; pHyd; pHyde; protein nm1054; six-transmembrane epithelial antigen of prostate 3; Tsap6; tumor suppressor-activated pathway protein 6
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391120,154,137 - 120,198,810 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1120,118,487 - 120,200,435 (-)EnsemblGRCm39 Ensembl
GRCm381120,226,414 - 120,271,081 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1120,190,757 - 120,272,705 (-)EnsemblGRCm38mm10GRCm38
MGSCv371122,122,993 - 122,167,659 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361122,054,752 - 122,092,804 (-)NCBIMGSCv36mm8
Celera1122,886,890 - 122,931,707 (-)NCBICelera
Cytogenetic Map1E2.3NCBI
cM Map152.66NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
1,2-dimethylhydrazine  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-dinitrotoluene  (ISO)
2-acetamidofluorene  (ISO)
2-butoxyethanol  (EXP)
3-chloropropane-1,2-diol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-aminobenzhydrazide  (ISO)
4-hydroxyphenyl retinamide  (EXP)
4-nitrophenol  (EXP)
6-propyl-2-thiouracil  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (ISO)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzene-1,2,4-triol  (ISO)
benzo[a]pyrene  (ISO)
benzophenone  (ISO)
beta-lapachone  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
buspirone  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
cantharidin  (EXP)
capsaicin  (ISO)
carbon nanotube  (EXP)
CGP 52608  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
deoxynivalenol  (EXP)
dexamethasone  (ISO)
diazinon  (ISO)
dieldrin  (ISO)
diethylstilbestrol  (ISO)
diquat  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
endosulfan  (ISO)
entinostat  (ISO)
epoxiconazole  (EXP)
ethanol  (EXP)
ethylparaben  (ISO)
formaldehyde  (ISO)
genistein  (ISO)
indometacin  (ISO)
iron atom  (EXP)
iron(0)  (EXP)
ketoconazole  (ISO)
levofloxacin  (ISO)
lipopolysaccharide  (ISO)
methyl methanesulfonate  (ISO)
nefazodone  (ISO)
nickel sulfate  (ISO)
nimesulide  (ISO)
oxaliplatin  (ISO)
ozone  (EXP)
panobinostat  (ISO)
paracetamol  (ISO)
perfluorooctanoic acid  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (ISO)
thiram  (ISO)
topotecan  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
triphenyl phosphate  (ISO)
triptonide  (EXP)
urethane  (ISO)
valdecoxib  (ISO)
valproic acid  (ISO)
vinclozolin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Cellular iron uptake, trafficking and metabolism: Key molecules and mechanisms and their roles in disease. Lane DJ, etal., Biochim Biophys Acta. 2015 May;1853(5):1130-44. doi: 10.1016/j.bbamcr.2015.01.021. Epub 2015 Feb 4.
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. MGD IEA MGD IEA
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8632996   PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:12429817   PMID:12477932   PMID:12606722   PMID:14610273   PMID:15319436   PMID:15782199   PMID:16141072  
PMID:16141073   PMID:16227996   PMID:16609065   PMID:18617898   PMID:18799693   PMID:18854576   PMID:18955558   PMID:21267068   PMID:21873635   PMID:22031863   PMID:22624035   PMID:22689674  
PMID:24194600   PMID:25515317   PMID:26287972   PMID:26642240   PMID:26911931   PMID:27113764   PMID:31350307   PMID:31393024   PMID:32554809   PMID:32862709   PMID:38355793  


Genomics

Comparative Map Data
Steap3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391120,154,137 - 120,198,810 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1120,118,487 - 120,200,435 (-)EnsemblGRCm39 Ensembl
GRCm381120,226,414 - 120,271,081 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1120,190,757 - 120,272,705 (-)EnsemblGRCm38mm10GRCm38
MGSCv371122,122,993 - 122,167,659 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361122,054,752 - 122,092,804 (-)NCBIMGSCv36mm8
Celera1122,886,890 - 122,931,707 (-)NCBICelera
Cytogenetic Map1E2.3NCBI
cM Map152.66NCBI
STEAP3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382119,223,834 - 119,265,652 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2119,223,831 - 119,265,652 (+)EnsemblGRCh38hg38GRCh38
GRCh372119,981,410 - 120,023,228 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362119,697,854 - 119,739,698 (+)NCBINCBI36Build 36hg18NCBI36
Celera2113,307,446 - 113,349,273 (+)NCBICelera
Cytogenetic Map2q14.2NCBI
HuRef2112,313,141 - 112,348,432 (+)NCBIHuRef
CHM1_12119,984,899 - 120,026,728 (+)NCBICHM1_1
T2T-CHM13v2.02119,657,360 - 119,699,155 (+)NCBIT2T-CHM13v2.0
Steap3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81333,904,710 - 33,950,100 (-)NCBIGRCr8
mRatBN7.21331,351,954 - 31,397,344 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1331,351,954 - 31,396,519 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1333,919,075 - 33,958,529 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01335,206,922 - 35,246,367 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01332,481,358 - 32,520,829 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01336,257,220 - 36,274,144 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1336,257,112 - 36,290,531 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01341,363,988 - 41,380,912 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1331,233,071 - 31,251,234 (-)NCBICelera
Cytogenetic Map13q11NCBI
Steap3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545910,441,752 - 10,485,269 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545910,441,906 - 10,485,235 (-)NCBIChiLan1.0ChiLan1.0
STEAP3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21321,232,416 - 21,274,503 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B21,269,221 - 21,289,476 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B6,166,296 - 6,208,338 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B119,760,650 - 119,787,051 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B119,752,363 - 119,787,051 (+)Ensemblpanpan1.1panPan2
STEAP3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11930,745,910 - 30,795,310 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1930,747,921 - 30,795,338 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1931,010,053 - 31,054,670 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01932,130,144 - 32,174,780 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1932,130,148 - 32,179,975 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11930,816,807 - 30,861,428 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01930,982,936 - 31,027,552 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01932,169,778 - 32,214,376 (-)NCBIUU_Cfam_GSD_1.0
Steap3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530390,496,040 - 90,533,500 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493646951,054,517 - 51,126,664 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493646951,084,250 - 51,121,738 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STEAP3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1524,736,594 - 24,787,865 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11524,736,556 - 24,785,376 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21528,419,225 - 28,467,997 (+)NCBISscrofa10.2Sscrofa10.2susScr3
STEAP3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11011,055,446 - 11,097,131 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1011,053,981 - 11,075,452 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606111,590,282 - 11,632,109 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Steap3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473225,913,736 - 25,958,582 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473225,913,034 - 25,958,537 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2037
Count of miRNA genes:606
Interacting mature miRNAs:729
Transcripts:ENSMUST00000112639, ENSMUST00000112640, ENSMUST00000112641, ENSMUST00000112643, ENSMUST00000140490
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12879492Ecgnq1_meccrine gland number QTL 1 (mouse)1103278062120535225Mouse
27095901Scvln8_msacral vertebrae length 2, 10 week (mouse)194127725172027567Mouse
15039333Nmrs1_mNAFLD-associated magnetic resonance shift 1 (mouse)189786512123786512Mouse
11039528Ccc3_mcolitis susceptibility in the Collaborative Cross 3 (mouse)13680142195051546Mouse
1302098Eila1_methanol induced locomotor activity 1 (mouse)Not determined1112008822175468938Mouse
10045976Tir6_mtrypanosome infection response 6 (mouse)Not determined193536855120529678Mouse
1302161Exq2_mexploratory and excitability QTL 2 (mouse)Not determined1118099720152099816Mouse
1357847Jckm2_mjuvenile cystic kidney modifier 2 (mouse)Not determined174991977133290937Mouse
4141627Bwq7_mbody weight, QTL 7 (mouse)Not determined192940909124497796Mouse
27226779Tibl1_mtibia length 1, 5 week (mouse)195527725162027569Mouse
10412185Hcs9_mhepatocarcinogenesis susceptibility 9 (mouse)Not determined163854690189303617Mouse
12879491Hfnq1_mhair follicle number QTL 1 (mouse)193310310123636759Mouse
1301979Melm1_mmelanoma modifier 1 (mouse)Not determined1109638262143638479Mouse
1301722Cia9_mcollagen induced arthritis QTL 9 (mouse)Not determined145783900189303617Mouse
13824984Twq5_mtestis weight QTL 5 (mouse)13069992184732197Mouse
12790991Aath1_maortic arch atherosclerosis 1 (mouse)186483929120483929Mouse
1357721Sle17_msystematic lupus erythematosus susceptibility 17 (mouse)Not determined139132808126445310Mouse
1301149Lrnx12_mlearning-contextual 12 (mouse)Not determined1112008822168186402Mouse
1301123Cd8mts2_mCD8 memory T cell subset 2 (mouse)Not determined196618386130618557Mouse
10045640Jckm4_mjuvenile cystic kidney modifier 4 (mouse)Not determined1116290836150290937Mouse
12790994Aaaq1_maortic arch angle QTL 1 (mouse)1109495943143495943Mouse
1301249Sbw1_msplenomegaly-NZB x NZW 1 (mouse)Not determined1112131005146131085Mouse
1357760Synch3_msynechia 3 (mouse)Not determined192901442126901550Mouse
1301193Lxw3_mlupus BXSB x NZW 3 (mouse)Not determined1102968534136968667Mouse
1558860W10q7_mweight 10 weeks QTL 7 (mouse)Not determined134760138150193871Mouse
10412162Nobq3_mNew Zealand obese QTL 3 (mouse)Not determined1103933405191225397Mouse
13452398Leusq5_mleucocytosis susceptibility QTL 5 (mouse)198474785126386517Mouse
1357488Splq3_mspleen weight QTL 3 (mouse)Not determined134760138150193871Mouse
4141914Gcsfis_mG-CSF induced splenomegaly (mouse)Not determined74516235148715579Mouse
27095928Pglq6_mpelvic girdle length QTL 6, 10 week (mouse)175976637148775742Mouse
13452395Leusq2_mleucocytosis susceptibility QTL 2 (mouse)180245593126386517Mouse
27095931Pglq1_mpelvic girdle length QTL 1, 5 week (mouse)175976637128527737Mouse
1301748Abbp1_mA/J and C57BL/6 blood pressure 1 (mouse)Not determined162946755120529678Mouse
1301753Tir3a_mtrypansomiasis infection response 3a (mouse)Not determined197053986131054190Mouse
1357439Popoa_mpremature ovulation and primary oocyte arrest (mouse)Not determined182643189135615379Mouse
4142291Aec2_mautoimmune exocrinopathy 2 (mouse)Not determined52457737182250592Mouse
1357753Kidq2_mkidney weight QTL 2 (mouse)Not determined134760138150193871Mouse
4141329Mleu1_mmyeloid leukemia survival 1 (mouse)Not determined89786512123786512Mouse
1300989Lrdg1_mlight induced retinal degeneration 1 (mouse)Not determined173755175147125370Mouse
1301536Pbbcp1_mperipheral blood B cell percentage 1 (mouse)Not determined199507660133507845Mouse
27095918Ulnl1_mulna length 1, 5 week (mouse)167339159129727737Mouse
1357600Obq17_mobesity QTL 17 (mouse)Not determined1110553179144553298Mouse
27095913Scvln2_msacral vertebrae length 2, 5 week (mouse)194127725148775742Mouse
1301350Nidd4k_mNidd4 on KK-A (mouse)Not determined782291982147125370Mouse
27095915Scvln13_msacral vertebrae length 2, 16 week (mouse)1117527730179827565Mouse
1300841Ssial1_msusceptibility to sialadenitis 1 (mouse)Not determined163920002153557562Mouse
26884448Sklq1_mskull length QTL 1, 5 week (mouse)175976637181327565Mouse
10401248Bglu12_mblood glucose level 12 (mouse)Not determined1110553179144553298Mouse


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001085409 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001379354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001379355 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_133186 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006529845 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC084310 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC139867 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK003108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK028961 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK078769 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171237 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK203257 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK217925 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK219258 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY029586 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY214462 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB857879 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC027251 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC037435 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY718114 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD742498 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466520 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U50961 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000112639   ⟹   ENSMUSP00000108258
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1120,154,362 - 120,198,153 (-)Ensembl
GRCm38.p6 Ensembl1120,226,632 - 120,270,423 (-)Ensembl
Ensembl Acc Id: ENSMUST00000112640   ⟹   ENSMUSP00000108259
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1120,154,153 - 120,193,014 (-)Ensembl
GRCm38.p6 Ensembl1120,226,423 - 120,265,284 (-)Ensembl
Ensembl Acc Id: ENSMUST00000112641   ⟹   ENSMUSP00000108260
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1120,152,116 - 120,198,812 (-)Ensembl
GRCm38.p6 Ensembl1120,224,386 - 120,271,082 (-)Ensembl
Ensembl Acc Id: ENSMUST00000112643   ⟹   ENSMUSP00000108262
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1120,154,383 - 120,200,435 (-)Ensembl
GRCm38.p6 Ensembl1120,226,653 - 120,272,705 (-)Ensembl
Ensembl Acc Id: ENSMUST00000140490   ⟹   ENSMUSP00000121046
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1120,118,487 - 120,192,985 (-)Ensembl
GRCm38.p6 Ensembl1120,190,757 - 120,265,255 (-)Ensembl
RefSeq Acc Id: NM_001085409   ⟹   NP_001078878
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391120,154,144 - 120,198,810 (-)NCBI
GRCm381120,226,414 - 120,271,080 (-)NCBI
MGSCv371122,122,993 - 122,167,659 (-)RGD
Celera1122,886,890 - 122,931,707 (-)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001379354   ⟹   NP_001366283
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391120,154,144 - 120,198,000 (-)NCBI
GRCm381120,226,414 - 120,270,270 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001379355   ⟹   NP_001366284
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391120,154,144 - 120,186,608 (-)NCBI
GRCm381120,226,414 - 120,258,878 (-)NCBI
Sequence:
RefSeq Acc Id: NM_133186   ⟹   NP_573449
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391120,154,144 - 120,193,016 (-)NCBI
GRCm381120,226,414 - 120,265,286 (-)NCBI
MGSCv371122,122,993 - 122,167,659 (-)RGD
Celera1122,886,890 - 122,931,707 (-)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006529845   ⟹   XP_006529908
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391120,154,137 - 120,198,805 (-)NCBI
GRCm381120,226,414 - 120,271,081 (-)NCBI
Sequence:
RefSeq Acc Id: NP_573449   ⟸   NM_133186
- Peptide Label: isoform b
- UniProtKB: Q924Z1 (UniProtKB/Swiss-Prot),   Q8C5F0 (UniProtKB/Swiss-Prot),   Q80ZF3 (UniProtKB/Swiss-Prot),   Q3TKE4 (UniProtKB/Swiss-Prot),   Q8CI59 (UniProtKB/Swiss-Prot),   A0A0R4J1G9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001078878   ⟸   NM_001085409
- Peptide Label: isoform b
- UniProtKB: Q924Z1 (UniProtKB/Swiss-Prot),   Q8C5F0 (UniProtKB/Swiss-Prot),   Q80ZF3 (UniProtKB/Swiss-Prot),   Q3TKE4 (UniProtKB/Swiss-Prot),   Q8CI59 (UniProtKB/Swiss-Prot),   A0A0R4J1G9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006529908   ⟸   XM_006529845
- Peptide Label: isoform X1
- UniProtKB: Q924Z1 (UniProtKB/Swiss-Prot),   Q8CI59 (UniProtKB/Swiss-Prot),   Q8C5F0 (UniProtKB/Swiss-Prot),   Q80ZF3 (UniProtKB/Swiss-Prot),   Q3TKE4 (UniProtKB/Swiss-Prot),   E9QN92 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001366283   ⟸   NM_001379354
- Peptide Label: isoform b
- UniProtKB: Q924Z1 (UniProtKB/Swiss-Prot),   Q8CI59 (UniProtKB/Swiss-Prot),   Q8C5F0 (UniProtKB/Swiss-Prot),   Q80ZF3 (UniProtKB/Swiss-Prot),   Q3TKE4 (UniProtKB/Swiss-Prot),   A0A0R4J1G9 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001366284   ⟸   NM_001379355
- Peptide Label: isoform a
- UniProtKB: Q924Z1 (UniProtKB/Swiss-Prot),   Q8CI59 (UniProtKB/Swiss-Prot),   Q8C5F0 (UniProtKB/Swiss-Prot),   Q80ZF3 (UniProtKB/Swiss-Prot),   Q3TKE4 (UniProtKB/Swiss-Prot)
Ensembl Acc Id: ENSMUSP00000108258   ⟸   ENSMUST00000112639
Ensembl Acc Id: ENSMUSP00000108259   ⟸   ENSMUST00000112640
Ensembl Acc Id: ENSMUSP00000108260   ⟸   ENSMUST00000112641
Ensembl Acc Id: ENSMUSP00000108262   ⟸   ENSMUST00000112643
Ensembl Acc Id: ENSMUSP00000121046   ⟸   ENSMUST00000140490
Protein Domains
Ferric oxidoreductase   Pyrroline-5-carboxylate reductase catalytic N-

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8CI59-F1-model_v2 AlphaFold Q8CI59 1-488 view protein structure

Promoters
RGD ID:6874732
Promoter ID:EPDNEW_M817
Type:multiple initiation site
Name:Steap3_2
Description:Mus musculus STEAP family member 3 , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M818  EPDNEW_M819  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381120,258,878 - 120,258,938EPDNEW
RGD ID:6874734
Promoter ID:EPDNEW_M818
Type:initiation region
Name:Steap3_1
Description:Mus musculus STEAP family member 3 , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M817  EPDNEW_M819  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381120,265,281 - 120,265,341EPDNEW
RGD ID:6874736
Promoter ID:EPDNEW_M819
Type:multiple initiation site
Name:Steap3_3
Description:Mus musculus STEAP family member 3 , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M817  EPDNEW_M818  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381120,271,080 - 120,271,140EPDNEW
RGD ID:6818546
Promoter ID:MM_KWN:1897
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day2,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000027638,   ENSMUST00000112640,   OTTMUST00000050945
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361122,161,666 - 122,162,166 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1915678 AgrOrtholog
Ensembl Genes ENSMUSG00000026389 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000112639 ENTREZGENE
  ENSMUST00000112639.8 UniProtKB/TrEMBL
  ENSMUST00000112640 ENTREZGENE
  ENSMUST00000112640.8 UniProtKB/TrEMBL
  ENSMUST00000112641 ENTREZGENE
  ENSMUST00000112641.8 UniProtKB/TrEMBL
  ENSMUST00000112643 ENTREZGENE
  ENSMUST00000112643.2 UniProtKB/TrEMBL
  ENSMUST00000140490.8 UniProtKB/TrEMBL
Gene3D-CATH NAD(P)-binding Rossmann-like Domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Fe3_Rdtase_TM_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P5C_Rdtase_cat_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STEAP_metalloreductase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:68428 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1915678 ENTREZGENE
NCBI Gene 68428 ENTREZGENE
PANTHER DUDULIN-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  METALLOREDUCTASE STEAP3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam F420_oxidored UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ferric_reduct UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Steap3 PhenoGen
Superfamily-SCOP SSF51735 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0R4J1G9 ENTREZGENE, UniProtKB/TrEMBL
  D3YTP0_MOUSE UniProtKB/TrEMBL
  E9QN92 ENTREZGENE, UniProtKB/TrEMBL
  Q3TKE4 ENTREZGENE
  Q80ZF3 ENTREZGENE
  Q8C5F0 ENTREZGENE
  Q8CI59 ENTREZGENE
  Q924Z1 ENTREZGENE
  STEA3_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q3TKE4 UniProtKB/Swiss-Prot
  Q80ZF3 UniProtKB/Swiss-Prot
  Q8C5F0 UniProtKB/Swiss-Prot
  Q924Z1 UniProtKB/Swiss-Prot