Gna11 (guanine nucleotide binding protein, alpha 11)

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Gene: Gna11 (guanine nucleotide binding protein, alpha 11) Mus musculus

Analyze

Symbol:

Gna11

Name:

guanine nucleotide binding protein, alpha 11

RGD ID:

1551128

MGI Page

MGI

Description:

Enables G protein activity and phospholipase activator activity. Involved in several processes, including G protein-coupled receptor signaling pathway; ligand-gated ion channel signaling pathway; and positive regulation of insulin secretion. Acts upstream of or within several processes, including cellular response to pH; phospholipase C-activating dopamine receptor signaling pathway; and regulation of melanocyte differentiation. Is active in plasma membrane. Is expressed in several structures, including adrenal gland; alimentary system; cardiovascular system; central nervous system; and genitourinary system. Used to study autosomal dominant hypocalcemia 2. Human ortholog(s) of this gene implicated in autosomal dominant hypocalcemia 2 and familial hypocalciuric hypercalcemia 2. Orthologous to human GNA11 (G protein subunit alpha 11).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

Dsk; Dsk7; E430025L19; g alpha-11; G-protein subunit alpha-11; guanine nucleotide-binding protein subunit alpha-11; heterotrimeric guanine nucleotide-binding protein 1k; Hg1k

RGD Orthologs

Human

Rat

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	GNA11 (G protein subunit alpha 11)	HGNC	Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Gna11 (G protein subunit alpha 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Gna11 (G protein subunit alpha 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	GNA11 (G protein subunit alpha 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	GNA11 (G protein subunit alpha 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Gna11 (G protein subunit alpha 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	GNA11 (G protein subunit alpha 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	GNA11 (G protein subunit alpha 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Gna11 (G protein subunit alpha 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	GNAQ (G protein subunit alpha q)	HGNC	OrthoDB, OrthoMCL
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Gna11 (G protein subunit alpha 11)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	GNA11 (G protein subunit alpha 11)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|SonicParanoid)
Danio rerio (zebrafish):	gna11a (guanine nucleotide binding protein (G protein), alpha 11a (Gq class))	Alliance	DIOPT (OMA\|OrthoFinder\|PANTHER\|ZFIN)
Danio rerio (zebrafish):	gna11b (guanine nucleotide binding protein (G protein), alpha 11b (Gq class))	Alliance	DIOPT (InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG17760	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):	GPA2	Alliance	DIOPT (Ensembl Compara\|OrthoInspector\|PANTHER)
Caenorhabditis elegans (roundworm):	egl-30	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Galphaq	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	gna11	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	81,364,558 - 81,380,996 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	81,364,558 - 81,381,024 (-)	Ensembl		GRCm39 Ensembl
GRCm38	10	81,528,724 - 81,545,162 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	81,528,724 - 81,545,190 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	80,991,477 - 81,007,791 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	10	80,931,861 - 80,948,175 (-)	NCBI		MGSCv36	mm8
Celera	10	82,551,913 - 82,568,227 (-)	NCBI		Celera
Cytogenetic Map	10	C1	NCBI
cM Map	10	39.72	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autosomal dominant hypocalcemia 2 (IAGP,ISO)

CLOVES syndrome (ISO)

congenital heart disease (ISO)

Craniofacial Abnormalities (IMP)

familial hypocalciuric hypercalcemia 2 (ISO)

familial multiple nevi flammei (ISO)

genetic disease (ISO)

melanoma (ISO)

Neurodevelopmental Disorders (ISO)

skin melanoma (ISO)

uveal melanoma (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (EXP)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2,3,7,8-Tetrachlorodibenzofuran (ISO)

3,4-methylenedioxymethamphetamine (EXP,ISO)

4,4'-diaminodiphenylmethane (EXP)

4,4'-sulfonyldiphenol (EXP)

acetamide (ISO)

aflatoxin B1 (ISO)

aldehydo-D-glucose (ISO)

antirheumatic drug (ISO)

apocynin (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

arsenous acid (ISO)

atrazine (ISO)

benzo[a]pyrene (EXP,ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (ISO)

Bisphenol B (ISO)

bisphenol F (ISO)

butan-1-ol (ISO)

carbachol (ISO)

cisplatin (ISO)

D-glucose (ISO)

dextran sulfate (EXP)

diarsenic trioxide (ISO)

diazinon (ISO)

doxorubicin (ISO)

ethanol (EXP,ISO)

folic acid (EXP)

fulvestrant (ISO)

glucose (ISO)

ivermectin (ISO)

methotrexate (ISO)

methyl methanesulfonate (ISO)

N-ethyl-N-nitrosourea (EXP)

Nor-9-carboxy-delta9-THC (ISO)

paracetamol (ISO)

perfluorooctane-1-sulfonic acid (EXP)

progesterone (EXP)

sodium arsenite (EXP,ISO)

streptozocin (ISO)

tert-butyl hydroperoxide (EXP,ISO)

titanium dioxide (EXP)

trametinib (ISO)

trichloroethene (EXP)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

action potential (IBA,IDA)

adenylate cyclase-modulating G protein-coupled receptor signaling pathway (IBA)

cellular response to pH (IMP)

cranial skeletal system development (IGI)

developmental pigmentation (IMP)

endothelin receptor signaling pathway (IGI)

G protein-coupled receptor signaling pathway (IMP,ISA)

glutamate receptor signaling pathway (IMP)

heart development (IMP)

ion channel modulating, G protein-coupled receptor signaling pathway (IGI)

ligand-gated ion channel signaling pathway (IGI,IMP)

phospholipase C-activating dopamine receptor signaling pathway (IBA,IGI)

phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway (IGI)

phospholipase C-activating G protein-coupled receptor signaling pathway (IGI,IMP)

positive regulation of insulin secretion (IGI,IMP)

regulation of blood pressure (IGI)

regulation of melanocyte differentiation (IMP)

signal transduction (IEA)

skeletal system development (IMP)

Cellular Component

cytoplasm (ISO)

heterotrimeric G-protein complex (IBA,ISA,ISO,TAS)

membrane (IEA)

plasma membrane (IDA,IGI)

Molecular Function

alkylglycerophosphoethanolamine phosphodiesterase activity (ISO)

enzyme regulator activity (IMP,ISO)

G protein activity (IMP,ISO)

G protein-coupled receptor binding (IBA)

G-protein beta/gamma-subunit complex binding (IBA)

GTP binding (IEA)

GTPase activity (IBA,ISA,TAS)

guanyl nucleotide binding (IEA)

metal ion binding (IEA)

nucleotide binding (IEA)

protein binding (IPI)

protein-containing complex binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

acetylcholine signaling pathway via muscarinic acetylcholine receptors engaging G alphaq protein family (ISO)

angiotensin II signaling pathway via AT1 receptor (ISO)

Chagas disease pathway (IEA)

eicosanoid signaling pathway (ISO)

endothelin signaling pathway (ISO)

Entamoebiasis pathway (IEA)

G protein mediated signaling pathway via Galphaq family (ISO)

gonadotropin-releasing hormone signaling pathway (IEA)

long term depression (IEA)

oxytocin signaling pathway (ISO)

sphingosine 1-phosphate signaling pathway (ISO)

vasopressin signaling pathway (ISO)

vasopressin signaling pathway via receptor type 1 (ISO)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal alisphenoid bone morphology (IAGP)

abnormal behavior (IEA)

abnormal bone mineralization (IAGP)

abnormal breathing pattern (IAGP)

abnormal circulating calcium level (IAGP)

abnormal epiphyseal plate morphology (IAGP)

abnormal heart size (IAGP)

abnormal hyoid bone morphology (IAGP)

abnormal larynx morphology (IAGP)

abnormal nervous system electrophysiology (IAGP)

abnormal palatine bone morphology (IAGP)

abnormal parathyroid gland morphology (IAGP)

abnormal pterygoid process morphology (IAGP)

abnormal sphenoid bone morphology (IAGP)

abnormal thyroid follicular cell morphology (IAGP)

abnormal thyroid gland morphology (IAGP)

abnormal thyroid gland physiology (IAGP)

abnormal tympanic ring morphology (IAGP)

abnormal urine calcium level (IAGP)

abnormal vascular wound healing (IAGP)

abnormal zygomatic bone morphology (IAGP)

clonic seizures (IAGP)

common ventricle (IAGP)

darkened coat color (IAGP)

decreased activity of thyroid gland (IAGP)

decreased body length (IAGP)

decreased body size (IAGP)

decreased body weight (IAGP)

decreased bone mineral density (IAGP)

decreased bone trabecula number (IAGP)

decreased circulating amylase level (IEA)

decreased circulating calcium level (IAGP)

decreased circulating parathyroid hormone level (IAGP)

decreased circulating phosphate level (IEA)

decreased circulating thyroxine level (IAGP)

decreased circulating total protein level (IEA)

decreased circulating triglyceride level (IEA)

decreased compact bone thickness (IAGP)

decreased erythrocyte cell number (IEA)

decreased hematocrit (IEA)

decreased hemoglobin content (IEA)

decreased mean corpuscular volume (IEA)

decreased mean systemic arterial blood pressure (IAGP)

decreased nitrate level (IAGP)

decreased pulmonary respiratory rate (IAGP)

decreased response of heart to induced stress (IAGP)

decreased susceptibility to type I hypersensitivity reaction (IAGP)

decreased systemic arterial blood pressure (IAGP)

decreased vascular permeability (IAGP)

decreased vasoconstriction (IAGP)

decreased vasodilation (IAGP)

delayed endochondral bone ossification (IAGP)

domed cranium (IAGP)

embryonic lethality during organogenesis, complete penetrance (IAGP)

gliosis (IAGP)

heart hypoplasia (IAGP)

hemopericardium (IAGP)

hepatic steatosis (IAGP)

hippocampal neuron degeneration (IAGP)

hyperpigmentation (IAGP)

hyporesponsive to tactile stimuli (IAGP)

hypoxia (IAGP)

increased bone resorption (IAGP)

increased bone trabecular spacing (IAGP)

increased circulating calcium level (IEA)

increased circulating parathyroid hormone level (IAGP)

increased circulating phosphate level (IAGP)

increased circulating thyroid-stimulating hormone level (IAGP)

increased circulating triglyceride level (IAGP)

increased ear pigmentation (IAGP)

increased foot pad pigmentation (IAGP)

increased liver triglyceride level (IAGP)

increased red blood cell distribution width (IEA)

increased susceptibility to hypertension (IAGP)

increased tail pigmentation (IAGP)

increased urine calcium level (IAGP)

incus hypoplasia (IAGP)

lower jaw to upper jaw transformation (IAGP)

malleus hypoplasia (IAGP)

neonatal lethality, complete penetrance (IAGP)

no abnormal phenotype detected (IAGP)

perinatal lethality, incomplete penetrance (IAGP)

postnatal growth retardation (IAGP)

postnatal lethality (IAGP)

premature death (IAGP)

preweaning lethality, incomplete penetrance (IAGP)

proportional dwarf (IAGP)

rachitic rosary (IAGP)

seizures (IAGP)

short mandible (IAGP)

short snout (IAGP)

short tibia (IEA)

small thyroid gland (IAGP)

stapes hypoplasia (IAGP)

thrombocytopenia (IEA)

tonic-clonic seizures (IAGP)

trabecula carnea hypoplasia (IAGP)

ventricular myocardium compact layer hypoplasia (IAGP)

vertebral fusion (IEA)

wide cranial sutures (IAGP)

References

References - curated

#	Reference Title	Reference Citation
1.	Molecular properties of muscarinic acetylcholine receptors.	Haga T Proc Jpn Acad Ser B Phys Biol Sci. 2013;89(6):226-56.
2.	Science review: Vasopressin and the cardiovascular system part 1--receptor physiology.	Holmes CL, etal., Crit Care. 2003 Dec;7(6):427-34. Epub 2003 Jun 26.
3.	Pleiotropic AT1 receptor signaling pathways mediating physiological and pathogenic actions of angiotensin II.	Hunyady L and Catt KJ, Mol Endocrinol. 2006 May;20(5):953-70. Epub 2005 Sep 1.
4.	MGDs mouse GO annotations	MGD data from the GO Consortium
5.	MGD IEA	MGD IEA
6.	Embryonic cardiomyocyte hypoplasia and craniofacial defects in G alpha q/G alpha 11-mutant mice.	Offermanns S, etal., EMBO J 1998 Aug 3;17(15):4304-12.
7.	Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.	Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
8.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
9.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
10.	PID Annotation Import Pipeline	Pipeline to import Pathway Interaction Database annotations from NCI into RGD
11.	Comparative maps of human 19p13.3 and mouse chromosome 10 allow identification of sequences at evolutionary breakpoints.	Puttagunta R, etal., Genome Res 2000 Sep;10(9):1369-80.
12.	Mouse MP Annotation Import Pipeline	RGD automated import pipeline
13.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
15.	Regulation of phosphoinositide-specific phospholipase C.	Rhee SG Annu Rev Biochem. 2001;70:281-312.

Additional References at PubMed

PMID:1302014	PMID:1707501	PMID:1846707	PMID:2123549	PMID:2508088	PMID:3133654	PMID:8588930	PMID:8836152	PMID:8838318	PMID:8858601	PMID:8889548	PMID:9607776
PMID:9765251	PMID:10349636	PMID:10629036	PMID:10818132	PMID:10829070	PMID:11042159	PMID:11076861	PMID:11217851	PMID:11438569	PMID:11443126	PMID:11544199	PMID:11689889
PMID:11826096	PMID:12351712	PMID:12477932	PMID:12533510	PMID:12648486	PMID:14610273	PMID:15175381	PMID:15322542	PMID:15340067	PMID:15713647	PMID:15782199	PMID:15872115
PMID:15936338	PMID:16141072	PMID:16141073	PMID:16251183	PMID:16602821	PMID:16847339	PMID:16988000	PMID:17023430	PMID:17194762	PMID:17374359	PMID:17482476	PMID:17694176
PMID:18084302	PMID:18086886	PMID:18199583	PMID:18287559	PMID:18583341	PMID:18854320	PMID:18991294	PMID:19171764	PMID:19320717	PMID:20023120	PMID:20372981	PMID:20440069
PMID:20715175	PMID:20886089	PMID:21190563	PMID:21267068	PMID:21345793	PMID:21357625	PMID:21677750	PMID:21812758	PMID:21873635	PMID:22562663	PMID:22580821	PMID:22733973
PMID:22794259	PMID:22972902	PMID:23129751	PMID:23696743	PMID:23836924	PMID:23973358	PMID:23988737	PMID:24081657	PMID:24194600	PMID:24308950	PMID:24591653	PMID:24838176
PMID:24870805	PMID:24958088	PMID:25093805	PMID:25495873	PMID:25595485	PMID:25832730	PMID:25857352	PMID:26075576	PMID:26168216	PMID:26208885	PMID:26272756	PMID:26377475
PMID:26410627	PMID:26476043	PMID:26531127	PMID:26595811	PMID:26628681	PMID:26843449	PMID:26938869	PMID:27006198	PMID:27300035	PMID:27348266	PMID:27364226	PMID:27797339
PMID:27811142	PMID:28194446	PMID:28194447	PMID:28301547	PMID:28378742	PMID:28578927	PMID:28706196	PMID:28883467	PMID:29046478	PMID:29107092	PMID:29490280	PMID:29747224
PMID:30068389	PMID:30270038	PMID:30301804	PMID:30936140	PMID:31091422	PMID:31461351	PMID:31549965	PMID:31857598	PMID:31896584	PMID:32325033	PMID:32332099	PMID:32576659
PMID:33166186	PMID:33378226	PMID:34864945

Genomics

Comparative Map Data

Gna11
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	81,364,558 - 81,380,996 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	81,364,558 - 81,381,024 (-)	Ensembl		GRCm39 Ensembl
GRCm38	10	81,528,724 - 81,545,162 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	81,528,724 - 81,545,190 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	80,991,477 - 81,007,791 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	10	80,931,861 - 80,948,175 (-)	NCBI		MGSCv36	mm8
Celera	10	82,551,913 - 82,568,227 (-)	NCBI		Celera
Cytogenetic Map	10	C1	NCBI
cM Map	10	39.72	NCBI

GNA11
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	3,094,362 - 3,123,999 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	19	3,094,362 - 3,123,999 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	3,094,360 - 3,123,997 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	3,045,408 - 3,072,468 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	3,045,529 - 3,072,452	NCBI
Celera	19	3,028,658 - 3,055,719 (+)	NCBI		Celera
Cytogenetic Map	19	p13.3	NCBI
HuRef	19	2,861,199 - 2,888,094 (+)	NCBI		HuRef
CHM1_1	19	3,110,108 - 3,121,429 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	19	3,068,114 - 3,097,735 (+)	NCBI		T2T-CHM13v2.0

Gna11
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	7	8,163,752 - 8,177,636 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	8,162,750 - 8,179,812 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	11,049,827 - 11,063,675 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	7	12,925,490 - 12,939,339 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	7	10,792,631 - 10,806,445 (+)	NCBI	Rnor_WKY
Rnor_6.0	7	11,033,400 - 11,047,284 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	11,033,317 - 11,047,437 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	11,200,712 - 11,214,475 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	9,636,748 - 9,662,492 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	9,636,747 - 9,662,492 (+)	NCBI
Celera	7	6,354,654 - 6,368,340 (+)	NCBI		Celera
Cytogenetic Map	7	q11	NCBI

Gna11
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955495	5,285,380 - 5,302,631 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955495	5,286,891 - 5,302,631 (-)	NCBI	ChiLan1.0	ChiLan1.0

GNA11
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	19	6,723,585 - 6,753,319 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	2,120,398 - 2,149,161 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	3,074,484 - 3,102,124 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	3,074,483 - 3,102,124 (+)	Ensembl	panpan1.1		panPan2

GNA11
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Dog10K_Boxer_Tasha	20	55,871,216 - 55,890,787 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	56,806,259 - 56,825,830 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	56,806,259 - 56,825,830 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	55,861,412 - 55,880,956 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	56,345,542 - 56,365,145 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	56,544,290 - 56,563,840 (-)	NCBI		UU_Cfam_GSD_1.0

Gna11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	216,045,637 - 216,064,006 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936588	1,770,771 - 1,789,170 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936588	1,770,777 - 1,789,143 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GNA11
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	75,437,201 - 75,457,092 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	75,439,405 - 75,456,855 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	76,071,093 - 76,088,406 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3
Pig Cytomap	2	q21-q24	NCBI

GNA11
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	2,858,880 - 2,887,694 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	2,858,937 - 2,887,704 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666081	5,694,672 - 5,723,312 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Gna11
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624828	6,077,851 - 6,093,750 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624828	6,078,485 - 6,093,744 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Gna11
327 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	1511
Count of miRNA genes:	663
Interacting mature miRNAs:	851
Transcripts:	ENSMUST00000043604, ENSMUST00000134354, ENSMUST00000146984
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1357740	Obsty3_m	obesity 3 (mouse)			Not determined		10	8235478	116190980	Mouse
1301386	Sysbp1_m	systolic blood pressure 1 (mouse)			Not determined		10	10108265	87401095	Mouse
1357825	Kidpq2_m	kidney weight percentage QTL 2 (mouse)			Not determined		10	12704051	84079784	Mouse
1357656	Hrtq3_m	heart weight QTL 3 (mouse)			Not determined		10	12704051	84079784	Mouse
1357864	Scfpq1_m	subcutaneous fat pad percentage QTL 1 (mouse)			Not determined		10	12704051	84079784	Mouse
39128215	Lwq17_m	liver weight QTL 17 (mouse)					10	12704051	84079784	Mouse
4141956	Egq7_m	early growth QTL 7 (mouse)			Not determined			12704051	84079784	Mouse
4141943	W6q6_m	weight 6 weeks QTL 6 (mouse)			Not determined			12704051	84079784	Mouse
4142272	W10q5_m	weight 10 weeks QTL 5 (mouse)			Not determined			12704051	84079784	Mouse
4142380	W3q11_m	weight 3 weeks QTL 11 (mouse)			Not determined			12704051	84079784	Mouse
1302067	Scc9_m	colon tumor susceptibility 9 (mouse)			Not determined		10	18259333	125575232	Mouse
27226772	Tibl13_m	tibia length 13, 10 week (mouse)					10	18875748	129635869	Mouse
1558757	Eae34_m	experimental allergic encephalomyelitis susceptibility 34 (mouse)			Not determined		10	21408154	114217230	Mouse
26884403	Cvht8_m	cranial vault height 8, 16 week (mouse)					10	22875899	91035862	Mouse
26884426	Cvht1_m	cranial vault height 1, 5 week (mouse)					10	24675898	121035905	Mouse
27095911	Pglq15_m	pelvic girdle length QTL 15, 16 week (mouse)					10	39175996	129635869	Mouse
27226764	Tibl19_m	tibia length 19, 16 week (mouse)					10	39175996	129635869	Mouse
26884411	Bzwq8_m	bi-zygomatic width QTL 8, 10 week (mouse)					10	44876096	115935905	Mouse
26884407	Bzwq14_m	bi-zygomatic width QTL 14, 16 wee (mouse)					10	45476096	120635905	Mouse
4142313	Angvq1_m	angiogenesis by VEGF QTL 1 (mouse)			Not determined			46720403	82491121	Mouse
1302150	Bbaa18_m	B.burgdorferi-associated arthritis 18 (mouse)			Not determined		10	49338012	83338157	Mouse
10045641	Jckm3_m	juvenile cystic kidney modifier 3 (mouse)			Not determined		10	49848187	83848412	Mouse
1300597	Skull14_m	skull morphology 14 (mouse)			Not determined		10	49848187	83848412	Mouse
4142169	Pbwg16_m	postnatal body weight growth 16 (mouse)			Not determined		10	49848187	83848412	Mouse
1357737	Hpcr2_m	hepatocarcinogen resistance 2 (mouse)			Not determined		10	49848222	83848397	Mouse
1301966	Lifespan2_m	life span 2 (mouse)			Not determined		10	49848222	83848397	Mouse
1301502	Eae17_m	susceptibility to experimental allergic encephalomyelitis 17 (mouse)			Not determined		10	51091490	85091639	Mouse
1300882	Ath17_m	atherosclerosis 17 (mouse)			Not determined		10	51091490	85091639	Mouse
1301380	Cia8_m	collagen induced arthritis QTL 8 (mouse)			Not determined		10	51493400	82491121	Mouse
14746991	Manh68_m	mandible shape 68 (mouse)					10	52280497	86280497	Mouse
1301787	Bsc1_m	brain size control 1 (mouse)			Not determined		10	58516969	92517096	Mouse
26884450	Sklq15_m	skull length QTL 15, 16 week (mouse)					10	59335822	122335905	Mouse
13208560	Wght9_m	weight 9 (mouse)					10	59835822	120835905	Mouse
26884424	Zlq9_m	zygomatic length QTL 9, 16 week (mouse)					10	63935779	115935905	Mouse
1302060	El3_m	epilepsy 3 (mouse)			Not determined		10	65490938	99491121	Mouse
1300533	Aem3_m	anti-erythrocyte autoantibody modifier 3 (mouse)			Not determined		10	65490938	99491121	Mouse
1301737	Insq9_m	insulin QTL 9 (mouse)			Not determined		10	65490938	99491121	Mouse
1302035	Lmb4_m	lupus in MRL and B6 F2 cross (mouse)			Not determined		10	66848187	92258673	Mouse
26884447	Sklq9_m	skull length QTL 9, 10 week (mouse)					10	67335830	111735905	Mouse
26884430	Zlq5_m	zygomatic length QTL 5, 10 week (mouse)					10	67835830	124835905	Mouse
26884405	Huml2_m	humerus length 2, 5 week (mouse)					10	69735830	130430862	Mouse
11039497	Ltpr5a_m	Leishmania tropica response 5a (mouse)					10	73506901	107507047	Mouse
4142107	Obrq12_m	obesity resistance QTL 12 (mouse)			Not determined			73987216	82491121	Mouse
11353832	Pcholq4_m	plasma cholesterol QTL 4 (mouse)					10	73987216	125515907	Mouse
11353843	Gluq1_m	blood glucose QTL 1 (mouse)					10	73987216	125515907	Mouse
1357632	Vtbt9_m	vertebral trabecular bone trait 9 (mouse)			Not determined		10	75338568	109338767	Mouse
4142137	Femwf3_m	femur work to failure 3 (mouse)			Not determined			75338568	109338767	Mouse
1300975	Fembrs3_m	femur breaking strength 3 (mouse)			Not determined		10	75338568	109338767	Mouse
11251717	Siim1_m	stress induced immobility 1 (mouse)					10	78381268	112381268	Mouse

Markers in Region

RH127565

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	10	81,528,793 - 81,528,994	UniSTS	GRCm38
MGSCv37	10	80,991,538 - 80,991,739	UniSTS	GRCm37
Celera	10	82,551,974 - 82,552,175	UniSTS
Cytogenetic Map	10	C1	UniSTS
cM Map	10	43.0	UniSTS

Gna11

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
MGSCv37	10	80,993,366 - 80,993,563	UniSTS	GRCm37
Celera	10	82,553,802 - 82,553,999	UniSTS
Cytogenetic Map	10	C1	UniSTS
cM Map	10	43.0	UniSTS

UniSTS:236416

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	10	81,529,666 - 81,529,928	UniSTS	GRCm38
MGSCv37	10	80,992,411 - 80,992,673	UniSTS	GRCm37
Celera	10	82,552,847 - 82,553,109	UniSTS
Cytogenetic Map	10	C1	UniSTS
cM Map	10	43.0	UniSTS

UniSTS:224669

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	10	81,530,616 - 81,530,719	UniSTS	GRCm38
MGSCv37	10	80,993,361 - 80,993,464	UniSTS	GRCm37
Celera	10	82,553,797 - 82,553,900	UniSTS
Cytogenetic Map	10	C1	UniSTS
cM Map	10	43.0	UniSTS

Gna11

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	10	81,530,621 - 81,530,818	UniSTS	GRCm38
MGSCv37	10	80,993,366 - 80,993,563	UniSTS	GRCm37
Celera	10	82,553,802 - 82,553,999	UniSTS
Cytogenetic Map	10	C1	UniSTS

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_010301	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC159474	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AH004855	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK088773	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK139289	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK143685	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK193533	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK196890	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK217650	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY974591	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC011169	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CD741377	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466553	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	M55411	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	M57617	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	OU667066	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSMUST00000043604 ⟹ ENSMUSP00000043190

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	10	81,364,558 - 81,381,024 (-)	Ensembl
GRCm38.p6 Ensembl	10	81,528,724 - 81,545,190 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000134354

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	10	81,368,967 - 81,370,967 (-)	Ensembl
GRCm38.p6 Ensembl	10	81,533,133 - 81,535,133 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000146984

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	10	81,366,121 - 81,367,849 (-)	Ensembl
GRCm38.p6 Ensembl	10	81,530,287 - 81,532,015 (-)	Ensembl

RefSeq Acc Id:

NM_010301 ⟹ NP_034431

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	10	81,364,558 - 81,380,996 (-)	NCBI
GRCm38	10	81,528,724 - 81,545,162 (-)	NCBI
MGSCv37	10	80,991,477 - 81,007,791 (-)	RGD
Celera	10	82,551,913 - 82,568,227 (-)	RGD
cM Map	10		ENTREZGENE

Sequence:

show sequence

GCGCGCAGCCGTGCGGCCCCTCCCATTGGCCGCGCCGCCTGCCCGTCCCGGGGCCCGTGGCAGC
GCTTCAGGTCCTCGGGCGCCGGCGCTCGGTGGCGACGGCTGCGGGTAGCGGCGGCGGCGGCGGC
TGCGCTGCACGGCGCGGACGGTGGACGCGCCTCTGGGGCCGGGCCGTGGCCTTCGGGGAACCGG
GAAGAGGTAGGGCCGGGCCGGCGGCAGCCGGAGGACCGCGACGATGACTCTGGAGTCCATGATG
GCGTGTTGCCTGAGCGACGAGGTGAAGGAGTCGAAGCGCATCAACGCGGAGATCGAGAAACAGC
TGCGGCGGGACAAGCGCGACGCCCGGCGCGAGCTCAAGCTGCTGCTACTTGGCACTGGCGAGAG
CGGGAAGAGTACCTTCATCAAGCAGATGCGCATCATCCACGGGGCCGGCTACTCGGAGGAGGAC
AAGCGCGGCTTCACCAAGTTGGTGTACCAGAACATCTTTACCGCCATGCAGGCCATGGTGCGCG
CCATGGAGACGCTCAAGATCCTCTACAAGTATGAGCAGAACAAGGCCAATGCACTCCTGATCCG
GGAGGTCGATGTGGAGAAGGTCACAACTTTTGAGCACCAGTATGTGAATGCCATCAAGACGCTG
TGGAGTGACCCTGGTGTCCAGGAGTGTTACGATCGCAGGCGGGAGTTCCAGCTATCTGACTCGG
CTAAGTACTACTTGACGGACGTGGACCGCATCGCCACAGTAGGCTACCTGCCCACCCAGCAGGA
TGTGCTGCGGGTACGCGTGCCCACCACTGGCATCATCGAGTACCCGTTTGACCTGGAGAACATC
ATCTTCAGGATGGTGGATGTGGGCGGGCAGAGGTCAGAGCGCAGGAAGTGGATCCATTGCTTTG
AGAACGTGACTTCCATCATGTTCTTGGTGGCACTAAGCGAGTATGACCAAGTCCTGGTGGAGTC
AGACAATGAGAACCGCATGGAGGAGAGCAAGGCCCTGTTCCGCACAATCATCACCTACCCCTGG
TTCCAGAACTCGTCTGTCATTCTCTTCCTCAACAAGAAGGACCTTCTAGAAGACAAGATCCTGC
ACTCACACTTGGTCGATTACTTCCCTGAGTTTGATGGGCCACAGAGGGATGCACAGGCCGCACG
CGAGTTCATTCTGAAGATGTTTGTGGACCTGAACCCTGACAGCGACAAAATCATCTACTCCCAC
TTCACGTGTGCCACCGACACCGAGAACATCCGCTTTGTGTTCGCAGCTGTGAAGGACACCATCC
TGCAGCTGAACCTGAAGGAGTACAACCTGGTGTGACCGCGGCATGGCTGCCACCAGGGCCAGCT
TCCTCCGCATCCGGTCACCCAAACCGAGGGACCTGGGCACACGGGGGCTGGGGCACATCTCTCT
TCCCGCTCACTTCCTGTCCCTGTCCCTCTTCCTCAAGGGCAGAGTGGCCTCATTTCGGCCTTGA
CTCAATGTGGCTTGAGGTTTTTTTTTTTCTTAGAAAACAAAAAAAAAAAAAAAAAAAAAAAAAA
AAGAAAGATACATGAACAGCAGTGTGCCCTCCCCAGAGATACCCCCACAGCCACAAGGCTATTA
AGATCAGGGCCACTGCAGCCCAAGCCCAAGTCCTGAGTTTGACTTCTCCCCCAGGAAAGCTGGA
GGCTTGGGGACCATGGACTACCCATTTTCTAAGTTATTGATATCCCGTATGCCCTCAGGGCTCG
CACCATCCCCCTAGACTCCCAAGAAGTGGGGGTGGGCGGCCCCTGTGCCTACCCTGGGAAGTGC
CTAATCGTTTTTTGTTTTGTTTTTGTTTTTGAAGAAAAGAGAAATATTCTCCACTCTGACTTGG
CAGCCAGGTGACACACTACAGGGTCTAGTGACCATAACCCCTGTGTTCCCCTGCTGCAGGCAGG
GCCTGCTGTTGGTGAAGTGGGGGGTGGGGAGATTAAGTCCCCAAGACCCGCTGCTCACTGACAT
GGCTAGGAAAGGCCCTGGGGACCCTGAGGGACTACGTGGAGTTGGGCAGCTGGAAGGACTGTCC
AAGTCTATGTGGTTCAGCAAGACTCGCCCTCCCCAAACCCAGTCAAGAGCGGGGTGCACAGGGG
CCTCTTCCAAATATTCTCAGGTCCGTACCCAGACATGGGCAGTGGCCCCACCCCACGCACTGGT
CCCTGGCCATAGTCACTGCACCTTGCCTGTTGCCTCCTAAACTAGAGGACCAGCGTATAGGAGG
TGATGGCCATGACCAGAGAGGACATAGGCAGGCCCCTGCTGCTCATATACACTACAGTGTCTAT
CTGTCTGTCTGTCAGATTTCTTTACTTTTTGCACGTGCGTTCTGGGCTTGGATAGCCAGCCACG
CCTTTGTCCTGCCTGCCAAGCTGGACTCCAGGCCCCAGAGTGCCCATGCACTCAGACACACGCC
AATCTGGGCAGTGGCCACATTGCCATCCCAGGCAGAAGGAAACAAGGGACCATGGGCATGACAG
AGCCCTAGAGTATGATGGGTGGCCATGATGATCACCCACATTCCTGGCCTCCAGCCCGTGGATT
CCCCCACCTTCCCACACTAGGCTCCTCTCCTGTCTCCAGTTGAGGGTCCGATCTGTGCCATCCC
ATACACTACAGAGCTACATGGATGGCAGGGTCATCCTATGAGAGACCCAGGTCCTCATAGTAGG
CATCTGTGTTGCACAATAGGAAGAGAAGTTGGGACTGTACAGGTGTCTGAGGCTGGACCACCCC
AAGCCGGCAAAGTGTTAGCCTCTCTTGAGCAGTATGTGCCAAGTGTGCTGGGCCACAGTGGCCA
CAGCCAAACCCCGGGGCAGCAACCAGCTCACCCAAGTGGTGAGTGGCAGGTTCTGCTCAGGGGA
AATGTGTCAGGGCCCCTTGGGGCTGTGTGCCACACAGGTCAGGATGGGGACCCCAGACTCCCTA
CTTCTGTCCTGGTCCTCACCAAGGAATGGCCTGATTGCAGGGGACACACTGGTTTCTTTGTGTC
CACCTTGGTGCACTGGGAGTGCCAACCACCATCCAGCACCTGGTCCAGGGAGCCAAGCCTGGCC
TGTGGTGGCTGCCAGCGGCTGCTGTGACCCTTGTATATTACAGTCCTAATTTCAAACTTCAGCC
TATTTAAGAGAACACTCAAAACACTATTTTTAATCCTCGTCCTTTGTGAAGCATGTTCCCGTGT
GAGGGGGAGGCTCAGGCACACAGCTCAGTGCCAGGCTCCTACAGGCCCTCGGCCATGGACGCCA
GGGTGCAAGCAGCAGGTCGGGGCCCTGACCCCTTAACCCAGAGGGTCTTGCTGAAGCCACCTTT
TCATATCTTTCTCTTGAATTCTGTTTTAAATCGGAATAAATTTTGTTCCTAAACTCTGAAAAAA
AAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_034431	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA63301	(Get FASTA)	NCBI Sequence Viewer
	AAA63305	(Get FASTA)	NCBI Sequence Viewer
	AAB36839	(Get FASTA)	NCBI Sequence Viewer
	AAH11169	(Get FASTA)	NCBI Sequence Viewer
	BAC40563	(Get FASTA)	NCBI Sequence Viewer
	BAE25496	(Get FASTA)	NCBI Sequence Viewer
	CAG9553584	(Get FASTA)	NCBI Sequence Viewer
	EDL31400	(Get FASTA)	NCBI Sequence Viewer
	P21278	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_034431 ⟸ NM_010301

- UniProtKB:

Q61939 (UniProtKB/Swiss-Prot), P21278 (UniProtKB/Swiss-Prot), Q3UPA1 (UniProtKB/TrEMBL), A0A6P5QA52 (UniProtKB/TrEMBL), A0A8C6HWB6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MTLESMMACCLSDEVKESKRINAEIEKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHG
AGYSEEDKRGFTKLVYQNIFTAMQAMVRAMETLKILYKYEQNKANALLIREVDVEKVTTFEHQY
VNAIKTLWSDPGVQECYDRRREFQLSDSAKYYLTDVDRIATVGYLPTQQDVLRVRVPTTGIIEY
PFDLENIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFR
TIITYPWFQNSSVILFLNKKDLLEDKILHSHLVDYFPEFDGPQRDAQAAREFILKMFVDLNPDS
DKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNLV

hide sequence

RefSeq Acc Id:

ENSMUSP00000043190 ⟸ ENSMUST00000043604

Protein Domains

G-alpha

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P21278-F1-model_v2	AlphaFold	P21278	1-359	view protein structure

Promoters

RGD ID:

6819382

Promoter ID:

MM_KWN:5017

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

Brain, Spleen

Transcripts:

UC007GIK.1

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	10	80,994,106 - 80,995,307 (-)	MPROMDB

RGD ID:

6819383

Promoter ID:

MM_KWN:5018

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

Brain

Transcripts:

OTTMUST00000074980

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	10	80,997,206 - 80,997,706 (-)	MPROMDB

RGD ID:

6819381

Promoter ID:

MM_KWN:5019

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

3T3L1_Day0, 3T3L1_Day1, 3T3L1_Day3, BoneMarrow_0Hour, BoneMarrow_2Hour, BoneMarrow_4Hour, Brain, ES_Cell, Kidney, Liver, Lung, MEF_B4, MEF_B6, Spleen

Transcripts:

OTTMUST00000074975

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	10	81,007,476 - 81,008,322 (-)	MPROMDB

RGD ID:

8672826

Promoter ID:

EPDNEW_M14444

Type:

initiation region

Name:

Gna11_1

Description:

Mus musculus guanine nucleotide binding protein, alpha 11 , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	10	81,545,091 - 81,545,151	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:95766	AgrOrtholog
Ensembl Genes	ENSMUSG00000034781	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein	ENSMUSP00000043190	ENTREZGENE
	ENSMUSP00000043190.6	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSMUST00000043604	ENTREZGENE
	ENSMUST00000043604.6	UniProtKB/Swiss-Prot
Gene3D-CATH	1.10.400.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	3.40.50.300	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	Gprotein_alpha_Q	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Gprotein_alpha_su	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GproteinA_insert	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	mmu:14672	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD	MGI:95766	ENTREZGENE
NCBI Gene	14672	ENTREZGENE
PANTHER	GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT ALPHA-11	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR10218	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	G-alpha	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Gna11	PhenoGen
PRINTS	GPROTEINA	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GPROTEINAQ	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	G_ALPHA	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	G_alpha	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF47895	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF52540	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A6P5QA52	ENTREZGENE
	A0A8C6HWB6	ENTREZGENE
	GNA11_MOUSE	UniProtKB/Swiss-Prot, ENTREZGENE
	Q3UPA1	ENTREZGENE, UniProtKB/TrEMBL
	Q61939	ENTREZGENE
	Q8C2E2_MOUSE	UniProtKB/TrEMBL
	Q91X95_MOUSE	UniProtKB/TrEMBL
UniProt Secondary	Q61939	UniProtKB/Swiss-Prot

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - KEGG (archival)

Imported Annotations - PID (archival)

Mammalian Phenotype

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - KEGG (archival)

Imported Annotations - PID (archival)

Mammalian Phenotype