Unc13d (unc-13 homolog D) - Rat Genome Database

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Gene: Unc13d (unc-13 homolog D) Mus musculus
Analyze
Symbol: Unc13d
Name: unc-13 homolog D
RGD ID: 1550647
MGI Page MGI
Description: Predicted to enable small GTPase binding activity. Involved in positive regulation of substrate adhesion-dependent cell spreading. Acts upstream of or within several processes, including defense response to other organism; germinal center formation; and granuloma formation. Predicted to be located in Weibel-Palade body; cytosol; and lysosome. Predicted to be active in exocytic vesicle. Used to study familial hemophagocytic lymphohistiocytosis 3. Human ortholog(s) of this gene implicated in familial hemophagocytic lymphohistiocytosis 3. Orthologous to human UNC13D (unc-13 homolog D).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2610108D09Rik; FLJ00067; Ji; Jinx; likely ortholog of H. sapiens unc-13 homolog D (UNC13D); mFLJ00067; Munc13-; Munc13-4; protein unc-13 homolog D; RP23-42F6.5; unc-13 homolog D (C. elegans)
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911115,952,921 - 115,969,321 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11115,952,921 - 115,968,787 (-)EnsemblGRCm39 Ensembl
GRCm3811116,062,095 - 116,078,495 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11116,062,095 - 116,077,961 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711115,923,410 - 115,939,275 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611115,878,186 - 115,894,051 (-)NCBIMGSCv36mm8
Celera11127,824,298 - 127,840,219 (-)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1180.91NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3). Feldmann J, etal., Cell. 2003 Nov 14;115(4):461-73.
2. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. Mouse MP Annotation Import Pipeline RGD automated import pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11544199   PMID:12477932   PMID:15020428   PMID:16141072   PMID:16141073   PMID:16688530   PMID:17420270   PMID:18354201   PMID:18799693  
PMID:19120489   PMID:20435885   PMID:21148308   PMID:21239699   PMID:21267068   PMID:21551232   PMID:21606480   PMID:21677750   PMID:21746860   PMID:21873635   PMID:22589474   PMID:23115246  
PMID:23281710   PMID:23590328   PMID:23659589   PMID:23810565   PMID:24488096   PMID:25158625   PMID:25239803   PMID:25526309   PMID:25609709   PMID:25908104   PMID:26575293   PMID:26637270  
PMID:26637356   PMID:26680738   PMID:26720279   PMID:26800051   PMID:26916731   PMID:27079884   PMID:27701149   PMID:28077416   PMID:29141910   PMID:29519941   PMID:29674495   PMID:29884704  
PMID:30892133   PMID:31171812   PMID:32040544   PMID:32929010   PMID:36278424  


Genomics

Comparative Map Data
Unc13d
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911115,952,921 - 115,969,321 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11115,952,921 - 115,968,787 (-)EnsemblGRCm39 Ensembl
GRCm3811116,062,095 - 116,078,495 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11116,062,095 - 116,077,961 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711115,923,410 - 115,939,275 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611115,878,186 - 115,894,051 (-)NCBIMGSCv36mm8
Celera11127,824,298 - 127,840,219 (-)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1180.91NCBI
UNC13D
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381775,827,225 - 75,844,404 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1775,827,225 - 75,844,785 (-)EnsemblGRCh38hg38GRCh38
GRCh371773,823,306 - 73,840,485 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361771,334,901 - 71,352,393 (-)NCBINCBI36Build 36hg18NCBI36
Celera1770,413,355 - 70,430,847 (-)NCBICelera
Cytogenetic Map17q25.1NCBI
HuRef1769,249,056 - 69,266,442 (-)NCBIHuRef
CHM1_11773,888,239 - 73,905,757 (-)NCBICHM1_1
T2T-CHM13v2.01776,720,377 - 76,737,555 (-)NCBIT2T-CHM13v2.0
Unc13d
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.210101,296,755 - 101,311,513 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10101,296,776 - 101,311,687 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx10106,358,330 - 106,372,954 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.010105,821,421 - 105,836,045 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.010101,217,675 - 101,232,432 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.010104,613,907 - 104,628,664 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10104,613,928 - 104,628,676 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010103,656,707 - 103,671,473 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410106,170,475 - 106,185,215 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.110106,184,978 - 106,199,719 (-)NCBI
Celera1099,870,790 - 99,885,526 (-)NCBICelera
Cytogenetic Map10q32.1NCBI
Unc13d
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555066,407,723 - 6,423,406 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555066,407,073 - 6,423,406 (+)NCBIChiLan1.0ChiLan1.0
UNC13D
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan11796,695,680 - 96,714,177 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01769,777,570 - 69,794,877 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11775,327,849 - 75,345,282 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1775,328,572 - 75,344,842 (-)Ensemblpanpan1.1panPan2
UNC13D
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.194,753,300 - 4,766,751 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl94,753,166 - 4,766,756 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha95,433,452 - 5,446,892 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.095,423,494 - 5,436,930 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl95,423,348 - 5,436,929 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.195,463,219 - 5,476,653 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.095,573,315 - 5,586,743 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.095,633,988 - 5,647,426 (+)NCBIUU_Cfam_GSD_1.0
Unc13d
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244056025,388,869 - 5,403,744 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365941,008,327 - 1,021,878 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049365941,008,215 - 1,023,023 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UNC13D
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl125,573,668 - 5,589,085 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1125,573,428 - 5,598,914 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2125,520,083 - 5,535,817 (+)NCBISscrofa10.2Sscrofa10.2susScr3
UNC13D
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11645,836,659 - 45,856,805 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1645,838,175 - 45,857,201 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607716,591,807 - 16,612,493 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Unc13d
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248015,721,391 - 5,736,294 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248015,720,998 - 5,736,122 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Unc13d
539 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2516
Count of miRNA genes:771
Interacting mature miRNAs:971
Transcripts:ENSMUST00000075036, ENSMUST00000106450, ENSMUST00000106451, ENSMUST00000153408, ENSMUST00000155120, ENSMUST00000156545, ENSMUST00000173345, ENSMUST00000173943, ENSMUST00000174822
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
1301072Eae22_mexperimental allergic encephalomyelitis 22 (mouse)Not determined1182377698116377820Mouse
14747003Mancz9_mmandible centroid size 9 (mouse)1185844911119844911Mouse
15039374Adip29_madiposity 29 (mouse)1186608320120608320Mouse
15039376Bw42_mbody weight QTL 42 (mouse)1186608320120608320Mouse
15014785Mvlq1_mmacrovesicular liver lesion QTL 1 (mouse)1186608320120608320Mouse
27226789Feml16_mfemur length 16, 10 week (mouse)1187490826121873369Mouse
10044007Hbnr14_mHeligmosomoides bakeri nematode resistance 14 (mouse)Not determined1187502600121502698Mouse
11251723Ewc5_methanol withdrawal and consumption 5 (mouse)1189869251121973369Mouse
1558753Ath19_matherosclerosis 19 (mouse)Not determined1191604608121973369Mouse
1302034Pkccl_mprotein kinase C content in lungs (mouse)Not determined1191604608121973369Mouse
1301095El6_mepilepsy 6 (mouse)Not determined1193229183121973369Mouse
4141939Pregq2_mpregnancy QTL 2 (mouse)Not determined1194063779118022724Mouse
27226731Tibmd4_mtibia midshaft diameter 4, 10 week (mouse)1194190826118890826Mouse
4141465Dbm2_mdiabetes modifier 2 (mouse)Not determined94437183118022724Mouse
1301958Alcp18_malcohol preference locus 18 (mouse)Not determined1195403965121973369Mouse
1300944Alcp20_malcohol preference locus 20 (mouse)Not determined1195403965121973369Mouse
1300962Cd8mts4_mCD8 memory T cell subset 4 (mouse)Not determined1196137674121973369Mouse
1301057Nidd4_mnon-insulin-dependent diabetes mellitus 4 (mouse)Not determined1196810136121973369Mouse
1301983Berr2_mberghei resistance locus 2 (mouse)Not determined1198352609121973369Mouse
10043976Obq33_mobesity QTL 33 (mouse)Not determined1198500469121973369Mouse
10044001Alcw8_malcohol withdrawal 8 (mouse)Not determined1199254187121973369Mouse
11553867Stmm5_mskin tumor modifier of MSM 5 (mouse)11100058103121973369Mouse
11341721Rvfs2_mRift Valley fever susceptibility 2 (mouse)11100254186120887165Mouse
1301012Vispl_mvisual placing (mouse)Not determined11101022590121973369Mouse


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001009573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006534188 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006534189 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006534190 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006534192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_879738 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK011827 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK220199 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL607108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC046519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC141289 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG146628 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CF164660 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466558 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF127645 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF127646 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000075036   ⟹   ENSMUSP00000074549
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11115,952,922 - 115,968,787 (-)Ensembl
GRCm38.p6 Ensembl11116,062,096 - 116,077,961 (-)Ensembl
RefSeq Acc Id: ENSMUST00000106450   ⟹   ENSMUSP00000102058
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11115,952,921 - 115,968,576 (-)Ensembl
GRCm38.p6 Ensembl11116,062,095 - 116,077,750 (-)Ensembl
RefSeq Acc Id: ENSMUST00000106451   ⟹   ENSMUSP00000102059
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11115,952,922 - 115,968,787 (-)Ensembl
GRCm38.p6 Ensembl11116,062,096 - 116,077,961 (-)Ensembl
RefSeq Acc Id: ENSMUST00000153408   ⟹   ENSMUSP00000115327
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11115,966,934 - 115,967,877 (-)Ensembl
GRCm38.p6 Ensembl11116,076,108 - 116,077,051 (-)Ensembl
RefSeq Acc Id: ENSMUST00000155120
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11115,966,223 - 115,968,787 (-)Ensembl
GRCm38.p6 Ensembl11116,075,397 - 116,077,961 (-)Ensembl
RefSeq Acc Id: ENSMUST00000156545   ⟹   ENSMUSP00000118266
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11115,967,297 - 115,968,767 (-)Ensembl
GRCm38.p6 Ensembl11116,076,471 - 116,077,941 (-)Ensembl
RefSeq Acc Id: ENSMUST00000173345   ⟹   ENSMUSP00000133679
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11115,953,380 - 115,968,450 (-)Ensembl
GRCm38.p6 Ensembl11116,062,554 - 116,077,624 (-)Ensembl
RefSeq Acc Id: ENSMUST00000173943
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11115,959,621 - 115,961,181 (-)Ensembl
GRCm38.p6 Ensembl11116,068,795 - 116,070,355 (-)Ensembl
RefSeq Acc Id: ENSMUST00000174822   ⟹   ENSMUSP00000134260
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11115,953,464 - 115,968,416 (-)Ensembl
GRCm38.p6 Ensembl11116,062,638 - 116,077,590 (-)Ensembl
RefSeq Acc Id: NM_001009573   ⟹   NP_001009573
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911115,952,922 - 115,968,787 (-)NCBI
GRCm3811116,062,096 - 116,077,961 (-)NCBI
MGSCv3711115,923,410 - 115,939,275 (-)RGD
Celera11127,824,298 - 127,840,219 (-)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006534188   ⟹   XP_006534251
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911115,952,921 - 115,969,008 (-)NCBI
GRCm3811116,062,095 - 116,078,182 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006534189   ⟹   XP_006534252
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911115,952,921 - 115,969,321 (-)NCBI
GRCm3811116,062,095 - 116,078,495 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006534190   ⟹   XP_006534253
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911115,952,921 - 115,968,760 (-)NCBI
GRCm3811116,062,095 - 116,077,934 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006534192   ⟹   XP_006534255
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911115,952,921 - 115,968,233 (-)NCBI
GRCm3811116,062,095 - 116,077,404 (-)NCBI
Sequence:
RefSeq Acc Id: XR_879738
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911115,959,049 - 115,968,760 (-)NCBI
GRCm3811116,068,223 - 116,077,934 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_001009573   ⟸   NM_001009573
- UniProtKB: B2RUP2 (UniProtKB/Swiss-Prot),   Q80UG7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006534251   ⟸   XM_006534188
- Peptide Label: isoform X1
- UniProtKB: A3R4M5 (UniProtKB/Swiss-Prot),   A3R4M4 (UniProtKB/Swiss-Prot),   A2A856 (UniProtKB/Swiss-Prot),   Q571J0 (UniProtKB/Swiss-Prot),   B2RUP2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006534252   ⟸   XM_006534189
- Peptide Label: isoform X1
- UniProtKB: A3R4M5 (UniProtKB/Swiss-Prot),   A3R4M4 (UniProtKB/Swiss-Prot),   A2A856 (UniProtKB/Swiss-Prot),   Q571J0 (UniProtKB/Swiss-Prot),   B2RUP2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006534253   ⟸   XM_006534190
- Peptide Label: isoform X1
- UniProtKB: A3R4M5 (UniProtKB/Swiss-Prot),   A3R4M4 (UniProtKB/Swiss-Prot),   A2A856 (UniProtKB/Swiss-Prot),   Q571J0 (UniProtKB/Swiss-Prot),   B2RUP2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006534255   ⟸   XM_006534192
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSMUSP00000102058   ⟸   ENSMUST00000106450
RefSeq Acc Id: ENSMUSP00000102059   ⟸   ENSMUST00000106451
RefSeq Acc Id: ENSMUSP00000134260   ⟸   ENSMUST00000174822
RefSeq Acc Id: ENSMUSP00000133679   ⟸   ENSMUST00000173345
RefSeq Acc Id: ENSMUSP00000074549   ⟸   ENSMUST00000075036
RefSeq Acc Id: ENSMUSP00000115327   ⟸   ENSMUST00000153408
RefSeq Acc Id: ENSMUSP00000118266   ⟸   ENSMUST00000156545
Protein Domains
C2   MHD1   MHD2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B2RUP2-F1-model_v2 AlphaFold B2RUP2 1-1085 view protein structure

Promoters
RGD ID:6821281
Promoter ID:MM_KWN:10606
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Lung,   MEF_B4,   Spleen
Transcripts:ENSMUST00000106449,   ENSMUST00000106450,   ENSMUST00000106451,   NM_001009573,   OTTMUST00000007990,   OTTMUST00000007991,   OTTMUST00000007992,   OTTMUST00000007993,   UC007MJS.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3611115,938,926 - 115,939,782 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1917700 AgrOrtholog
Ensembl Genes ENSMUSG00000057948 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000074549 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000102058 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000102059 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000115327.2 UniProtKB/TrEMBL
  ENSMUSP00000118266.2 UniProtKB/TrEMBL
  ENSMUSP00000133679.2 UniProtKB/TrEMBL
  ENSMUSP00000134260 UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000075036 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000106450 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000106451 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000153408.8 UniProtKB/TrEMBL
  ENSMUST00000156545.2 UniProtKB/TrEMBL
  ENSMUST00000173345.8 UniProtKB/TrEMBL
  ENSMUST00000174822 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.357.50 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.58.1100 UniProtKB/Swiss-Prot
  2.60.40.150 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro C2_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MUN_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Munc13_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Munc13_dom-2 UniProtKB/Swiss-Prot
KEGG Report mmu:70450 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1917700 ENTREZGENE
NCBI Gene 70450 ENTREZGENE
PANTHER PROTEIN UNC-13 HOMOLOG D UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UNC-13-4A, ISOFORM B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam MUN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PF00168 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Unc13d PhenoGen
PROSITE MHD1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHD2 UniProtKB/Swiss-Prot
  PS50004 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SM00239 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF49562 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0R4J257_MOUSE UniProtKB/TrEMBL
  A2A855_MOUSE UniProtKB/TrEMBL
  A2A856 ENTREZGENE
  A2A858_MOUSE UniProtKB/TrEMBL
  A3R4M4 ENTREZGENE
  A3R4M5 ENTREZGENE
  B2RUP2 ENTREZGENE
  Q571J0 ENTREZGENE
  Q80UG7 ENTREZGENE, UniProtKB/TrEMBL
  UN13D_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary A2A856 UniProtKB/Swiss-Prot
  A3R4M4 UniProtKB/Swiss-Prot
  A3R4M5 UniProtKB/Swiss-Prot
  Q571J0 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-06-05 Unc13d  unc-13 homolog D    unc-13 homolog D (C. elegans)  Symbol and/or name change 5135510 APPROVED