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Gene: Rnd2 (Rho family GTPase 2) Mus musculus

Analyze

Symbol:

Rnd2

Name:

Rho family GTPase 2

RGD ID:

1550413

MGI Page

MGI

Description:

Predicted to enable GTP binding activity; GTPase activity; and protein kinase binding activity. Acts upstream of or within positive regulation of collateral sprouting. Predicted to be located in early endosome. Predicted to be active in cytosol and plasma membrane. Is expressed in brain. Orthologous to human RND2 (Rho family GTPase 2).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

A; aplysia ras-related homolog N (RhoN); Arhn; R; ras homolog gene family, member N; ras homolog N (RhoN); rho-related GTP-binding protein Rho7; rho-related GTP-binding protein RhoN; rho7; Rohn

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RND2 (Rho family GTPase 2)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Rnd2 (Rho family GTPase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Rnd2 (Rho family GTPase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RND2 (Rho family GTPase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RND2 (Rho family GTPase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Rnd2 (Rho family GTPase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RND2 (Rho family GTPase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RND2 (Rho family GTPase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Rnd2 (Rho family GTPase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Rnd2 (Rho family GTPase 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	RND2 (Rho family GTPase 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	rnd2 (Rho family GTPase 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	RHO3	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Saccharomyces cerevisiae (baker's yeast):	RHO4	Alliance	DIOPT (Ensembl Compara\|PANTHER)

Related Pseudogenes:

Gm4768

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	101,359,001 - 101,362,679 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	101,355,825 - 101,362,679 (+)	Ensembl		GRCm39 Ensembl
GRCm38	11	101,468,175 - 101,471,853 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	101,464,999 - 101,471,853 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	101,329,652 - 101,332,620 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	101,284,428 - 101,287,396 (+)	NCBI		MGSCv36	mm8
Celera	11	113,155,788 - 113,158,533 (+)	NCBI		Celera
Cytogenetic Map	11	D	NCBI
cM Map	11	65.12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

hereditary breast ovarian cancer syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (ISO)

1,2-dimethylhydrazine (EXP)

1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine (ISO)

17beta-estradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (ISO)

2-hydroxypropanoic acid (ISO)

3,4-methylenedioxymethamphetamine (EXP)

3-chloropropane-1,2-diol (ISO)

4,4'-sulfonyldiphenol (ISO)

5-aza-2'-deoxycytidine (ISO)

5-fluorouracil (ISO)

acetylsalicylic acid (ISO)

acrylamide (ISO)

all-trans-retinoic acid (ISO)

aristolochic acid A (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

buspirone (ISO)

cadmium dichloride (ISO)

carbamazepine (ISO)

chlordecone (EXP)

choline (EXP)

cisplatin (ISO)

cocaine (EXP)

dibutyl phthalate (EXP,ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

fenthion (EXP)

flavonoids (ISO)

folic acid (EXP,ISO)

furan (EXP)

gentamycin (ISO)

glafenine (ISO)

L-methionine (EXP)

leflunomide (ISO)

levofloxacin (ISO)

lipopolysaccharide (ISO)

mercury atom (ISO)

mercury(0) (ISO)

methylmercury chloride (ISO)

ozone (EXP)

p-chloromercuribenzoic acid (ISO)

phenylmercury acetate (ISO)

pirinixic acid (EXP)

rac-lactic acid (ISO)

resveratrol (ISO)

rotenone (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

SB 431542 (ISO)

sodium arsenate (EXP)

Soman (ISO)

sunitinib (ISO)

tamoxifen (ISO)

tetrachloromethane (ISO)

thioacetamide (ISO)

titanium dioxide (EXP)

trichostatin A (ISO)

triclosan (ISO)

urethane (ISO)

valproic acid (EXP,ISO)

vinclozolin (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

actin filament organization (IBA)

collateral sprouting (IMP)

positive regulation of collateral sprouting (IMP)

regulation of actin cytoskeleton organization (IBA)

signal transduction (IBA)

small GTPase-mediated signal transduction (IEA)

Cellular Component

acrosomal membrane (IEA)

cytosol (IBA)

early endosome (IEA,ISO)

plasma membrane (IBA)

Molecular Function

GTP binding (IBA,IEA)

GTPase activity (IBA,IEA)

protein binding (IPI,ISO)

protein kinase binding (IBA)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal action potential (IAGP)

abnormal cerebellar granule cell migration (IAGP)

abnormal dendrite arborization pattern (IAGP)

abnormal hippocampus neuron morphology (IAGP)

abnormal liver morphology (IEA)

abnormal myelination (IAGP)

abnormal pancreas morphology (IEA)

abnormal seminal vesicle morphology (IEA)

abnormal skin morphology (IEA)

abnormal spleen morphology (IEA)

abnormal urinary bladder morphology (IEA)

anophthalmia (IEA)

decreased myelin sheath thickness (IAGP)

enlarged spleen (IEA)

enlarged urinary bladder (IEA)

increased anxiety-related response (IAGP)

increased body length (IEA)

increased myelin sheath thickness (IAGP)

increased neuron apoptosis (IAGP)

prolonged RR interval (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Functional annotation of a full-length mouse cDNA collection.	Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2.	MGDs mouse GO annotations	MGD data from the GO Consortium
3.	Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.	Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8889548	PMID:10101234	PMID:10349636	PMID:11042159	PMID:11076861	PMID:12477932	PMID:14610273	PMID:16141072	PMID:16141073	PMID:17021036	PMID:18690213	PMID:18706977
PMID:18799693	PMID:19136556	PMID:21267068	PMID:21435554	PMID:21652654	PMID:21677750	PMID:21873635	PMID:21965613	PMID:22357615	PMID:22465231	PMID:22898830	PMID:22967998
PMID:24084125	PMID:24154525	PMID:24572910	PMID:25888806	PMID:27005988	PMID:27224923	PMID:29351579	PMID:29659809	PMID:29878134	PMID:30392794	PMID:32325033	PMID:33596091
PMID:34321999	PMID:34561615	PMID:38355793	PMID:39095712

Genomics

Comparative Map Data

Rnd2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	101,359,001 - 101,362,679 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	101,355,825 - 101,362,679 (+)	Ensembl		GRCm39 Ensembl
GRCm38	11	101,468,175 - 101,471,853 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	101,464,999 - 101,471,853 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	101,329,652 - 101,332,620 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	101,284,428 - 101,287,396 (+)	NCBI		MGSCv36	mm8
Celera	11	113,155,788 - 113,158,533 (+)	NCBI		Celera
Cytogenetic Map	11	D	NCBI
cM Map	11	65.12	NCBI

RND2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	43,025,231 - 43,032,041 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	43,025,231 - 43,032,041 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	41,177,248 - 41,184,058 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	38,430,784 - 38,437,584 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	17	38,430,890 - 38,434,223	NCBI
Celera	17	37,834,115 - 37,840,915 (+)	NCBI		Celera
Cytogenetic Map	17	q21.31	NCBI
HuRef	17	36,943,610 - 36,950,406 (+)	NCBI		HuRef
CHM1_1	17	41,412,791 - 41,419,591 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	17	43,883,786 - 43,890,596 (+)	NCBI		T2T-CHM13v2.0

Rnd2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	86,899,395 - 86,902,992 (+)	NCBI		GRCr8
mRatBN7.2	10	86,399,151 - 86,402,750 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	86,399,148 - 86,402,742 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	91,436,323 - 91,439,907 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	90,911,568 - 90,915,152 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	86,304,874 - 86,308,458 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	89,376,530 - 89,380,101 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	89,376,530 - 89,380,101 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	89,174,546 - 89,178,117 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	90,493,477 - 90,497,048 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	90,507,846 - 90,511,418 (+)	NCBI
Celera	10	85,120,594 - 85,124,165 (+)	NCBI		Celera
Cytogenetic Map	10	q31	NCBI

Rnd2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955451	16,806,507 - 16,809,146 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955451	16,806,527 - 16,809,091 (+)	NCBI	ChiLan1.0	ChiLan1.0

RND2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	21,943,714 - 21,965,916 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	23,833,084 - 23,855,193 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	14,276,880 - 14,298,023 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	14,521,510 - 14,528,209 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	14,521,510 - 14,528,209 (-)	Ensembl	panpan1.1		panPan2

RND2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	20,037,469 - 20,041,044 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	20,037,718 - 20,041,631 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	19,499,165 - 19,502,747 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	20,755,972 - 20,759,554 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	20,755,972 - 20,759,563 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	19,541,073 - 19,544,655 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	19,807,825 - 19,811,406 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	19,909,872 - 19,913,454 (-)	NCBI		UU_Cfam_GSD_1.0

Rnd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	19,351,796 - 19,356,326 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936490	17,718,205 - 17,726,574 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936490	17,718,813 - 17,725,556 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RND2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	19,866,603 - 19,870,211 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	19,866,597 - 19,870,205 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	20,012,174 - 20,015,782 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RND2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	63,259,677 - 63,270,880 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	63,257,660 - 63,270,800 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666077	34,044,367 - 34,050,584 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rnd2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624795	1,248,994 - 1,251,743 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624795	1,248,996 - 1,250,960 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Rnd2
129 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	542
Count of miRNA genes:	405
Interacting mature miRNAs:	448
Transcripts:	ENSMUST00000001347, ENSMUST00000134980, ENSMUST00000153185
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
27226783	Tibl5_m	tibia length 5, 5 week (mouse)					11	68190826	101890826	Mouse
1302034	Pkccl_m	protein kinase C content in lungs (mouse)			Not determined		11	91604608	121973369	Mouse
1301012	Vispl_m	visual placing (mouse)			Not determined		11	101022590	121973369	Mouse
4141367	Inf1_m	acute ozone induced inflammation (mouse)			Not determined			44630038	113058009	Mouse
1558812	Rafar_m	retinoic acid induced forelimb autopod reduction (mouse)			Not determined		11	70691198	104691366	Mouse
1301535	Pas5b_m	pulmonary adenoma susceptibility 5b (mouse)			Not determined		11	96176465	108806384	Mouse
1300766	Skull16_m	skull morphology 16 (mouse)			Not determined		11	81574481	115574636	Mouse
1301404	Sbmd4_m	spinal bone mineral density 4 (mouse)			Not determined		11	72019649	106019734	Mouse
12910539	Sstapa3_m	suseptibility to Staphylococcus aureus infection 3 (mouse)					11	96897693	110603991	Mouse
4142121	Tmc1m2_m	Tmc1 modifier 2 (mouse)			Not determined		11	56864027	114157957	Mouse
27226758	Femd3_m	femur midshaft diameter 3, 5 week (mouse)					11	80890826	101890826	Mouse
14747003	Mancz9_m	mandible centroid size 9 (mouse)					11	85844911	119844911	Mouse
1301640	Lore4_m	loss of righting induced by ethanol 4 (mouse)			Not determined		11	79156009	107616472	Mouse
10412288	Carg4_m	Candida albicans resistance gene 4 (mouse)			Not determined		11	81810267	115810267	Mouse
11251723	Ewc5_m	ethanol withdrawal and consumption 5 (mouse)					11	89869251	121973369	Mouse
1301681	Sle13_m	systematic lupus erythematosus susceptibility 13 (mouse)			Not determined		11	70691198	104691366	Mouse
4141339	Nilac2_m	nicotine induced locomotor activity 2 (mouse)			Not determined		11	70691198	104691366	Mouse
10413882	Moe1_m	modifier of epilepsy 1 (mouse)					11	77770978	111771099	Mouse
4141465	Dbm2_m	diabetes modifier 2 (mouse)			Not determined			94437183	118022724	Mouse
10045617	Heal26_m	wound healing/regeneration 26 (mouse)			Not determined		11	92939373	112544554	Mouse
10045616	Heal25_m	wound healing/regeneration 25 (mouse)			Not determined		11	77437183	111437322	Mouse
1357631	Motr1_m	modifier of tubby retinal degeneration 1 (mouse)			Not determined		11	87691198	103274115	Mouse
1301310	Tmevd5_m	Theiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 5 (mouse)			Not determined		11	72726125	106726289	Mouse
4142348	Pstc2_m	periosteal circumference 2 (mouse)			Not determined		11	72818615	106818733	Mouse
11341721	Rvfs2_m	Rift Valley fever susceptibility 2 (mouse)					11	100254186	120887165	Mouse
1301414	Heal10_m	wound healing/regeneration 10 (mouse)			Not determined		11	77437183	111437322	Mouse
1300651	Pcyts3_m	plasmacytoma susceptibility 3 (mouse)			Not determined		11	70691198	104691366	Mouse
1300649	Crhq1_m	compensatory renal hypertrophy QTL 1 (mouse)			Not determined		11	81574481	115574636	Mouse
27226789	Feml16_m	femur length 16, 10 week (mouse)					11	87490826	121873369	Mouse
14746970	Manh71_m	mandible shape 71 (mouse)					11	79416257	113416257	Mouse
10043865	T2dm5sa_m	type 2 diabetes mellitus 5 in SMXA RI mice (mouse)			Not determined		11	79813759	104502698	Mouse
39128214	Lwq20_m	liver weight QTL 20 (mouse)					11	12268637	118022724	Mouse
10043866	Adip19_m	adiposity 19 (mouse)			Not determined		11	72818615	106818733	Mouse
1301072	Eae22_m	experimental allergic encephalomyelitis 22 (mouse)			Not determined		11	82377698	116377820	Mouse
1300944	Alcp20_m	alcohol preference locus 20 (mouse)			Not determined		11	95403965	121973369	Mouse
4141939	Pregq2_m	pregnancy QTL 2 (mouse)			Not determined		11	94063779	118022724	Mouse
1301983	Berr2_m	berghei resistance locus 2 (mouse)			Not determined		11	98352609	121973369	Mouse
11038695	Par8_m	pulmonary adenoma resistance 8 (mouse)					11	77063779	111063918	Mouse
10043976	Obq33_m	obesity QTL 33 (mouse)			Not determined		11	98500469	121973369	Mouse
1301057	Nidd4_m	non-insulin-dependent diabetes mellitus 4 (mouse)			Not determined		11	96810136	121973369	Mouse
1301958	Alcp18_m	alcohol preference locus 18 (mouse)			Not determined		11	95403965	121973369	Mouse
15014785	Mvlq1_m	macrovesicular liver lesion QTL 1 (mouse)					11	86608320	120608320	Mouse
15039374	Adip29_m	adiposity 29 (mouse)					11	86608320	120608320	Mouse
1300962	Cd8mts4_m	CD8 memory T cell subset 4 (mouse)			Not determined		11	96137674	121973369	Mouse
13513919	Heal56_m	wound healing/ regeneration 56 (mouse)					11	101156468	101540293	Mouse
1301095	El6_m	epilepsy 6 (mouse)			Not determined		11	93229183	121973369	Mouse
27226731	Tibmd4_m	tibia midshaft diameter 4, 10 week (mouse)					11	94190826	118890826	Mouse
27226730	Tibmd1_m	tibia midshaft diameter 1, 5 week (mouse)					11	62590826	109390826	Mouse
15039376	Bw42_m	body weight QTL 42 (mouse)					11	86608320	120608320	Mouse
1558753	Ath19_m	atherosclerosis 19 (mouse)			Not determined		11	91604608	121973369	Mouse
10044001	Alcw8_m	alcohol withdrawal 8 (mouse)			Not determined		11	99254187	121973369	Mouse
11553867	Stmm5_m	skin tumor modifier of MSM 5 (mouse)					11	100058103	121973369	Mouse
10044007	Hbnr14_m	Heligmosomoides bakeri nematode resistance 14 (mouse)			Not determined		11	87502600	121502698	Mouse

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_009708	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB017787	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF016482	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK075970	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK170529	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AL590996	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC107022	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC127034	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC128475	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC139330	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC139331	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BY275340	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CD775326	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466558	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CS026799	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSMUST00000001347 ⟹ ENSMUSP00000001347

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	11	101,359,001 - 101,362,679 (+)	Ensembl
GRCm38.p6 Ensembl	11	101,468,175 - 101,471,853 (+)	Ensembl

Ensembl Acc Id:

ENSMUST00000134980

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	11	101,356,310 - 101,361,931 (+)	Ensembl
GRCm38.p6 Ensembl	11	101,465,484 - 101,471,105 (+)	Ensembl

Ensembl Acc Id:

ENSMUST00000153185

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	11	101,355,825 - 101,362,679 (+)	Ensembl
GRCm38.p6 Ensembl	11	101,464,999 - 101,471,853 (+)	Ensembl

RefSeq Acc Id:

NM_009708 ⟹ NP_033838

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	11	101,359,001 - 101,362,679 (+)	NCBI
GRCm38	11	101,468,175 - 101,471,853 (+)	NCBI
MGSCv37	11	101,329,652 - 101,332,620 (+)	RGD
Celera	11	113,155,788 - 113,158,533 (+)	RGD
cM Map	11		ENTREZGENE

Sequence:

show sequence

GGAGGGGGCCCGCAGCCCCGGGCGGGGGCTCGGCGCGGGCCCGCGAGATGCCGGTGTCGGCGGC
CCGAGAGGCTGCAGCTGCAGCGGCGGGGGAGGAGGCGGCAGAAGCGGCGGCTGTGCCCGGGAGG
GGGGCGGCGTGGGGGGCCGGCGCGTAGCCGGGACCATGGAGGGGCAGAGTGGCCGCTGCAAGAT
CGTAGTGGTGGGGGACGCGGAGTGCGGCAAGACAGCGTTGCTGCAGGTGTTCGCCAAGGACGCC
TACCCCGGGAGTTATGTCCCCACGGTGTTTGAGAACTACACTGCCAGCTTCGAGATCGACAAGC
GCCGCATTGAGCTCAACATGTGGGATACTTCAGGTTCCTCTTACTATGACAATGTCCGGCCTCT
GGCCTACCCGGATTCTGATGCTGTGCTTATCTGCTTTGACATTAGCCGGCCAGAAACACTGGAC
AGTGTCCTCAAGAAGTGGCAAGGAGAGACTCAGGAGTTTTGCCCCAATGCCAAGGTGGTGCTGG
TTGGCTGTAAGCTGGACATGCGGACTGACCTGGCCACACTGAGGGAGCTATCCAAGCAGAGACT
CATCCCTGTCACACATGAGCAGGGTACTGTGCTGGCCAAGCAAGTGGGAGCTGTGTCCTACGTT
GAATGTTCCTCCCGATCTTCTGAGCGCAGTGTCCGGGATGTCTTCCATGTGGCCACAGTGGCTT
CTCTCGGCCGTGGCCATAGGCAGCTACGTCGTACTGACTCTCGCCGGGGACTGCAGCGATCCAC
TCAACTGTCGGGACGGCCAGACCGGGGAAATGAGGGCGAGATGCATAAGGATCGAGCCAAGAGC
TGTAACCTCATGTGAGGGGTTGCAGTGGGGCAGAGAGGGGAGAGGGCTGGGTGAGAGACACGGT
TGTTCCCGTGGGTGCTCCTGGACTTTTTGACCTCCTGGCCCTGGCTGGAAGGTCAGGGCAGGCA
GAGGAGCAATTCTGGTTGGAGGAGCTAGAGGGTAGAAGGCTGTCACTCCTCACCCCATTCTCTA
CACCCTTATCCCTTCTCTGCTGCTAGCTGAGAGAGCTGACAGGGTAGGCATCTGGTACATGAAC
TTGGATAGGGCAGGTGGGGGTTTGGGAAACCAAGCAATGACTTTGGTTGAGTCTCCTATGTAAA
GTGTAACTTCCTTGCATACCCTGGTCCCCATATCCCATCTGCCTTCCCTAAGGAAAGTGTCCAT
TTGATGACCTTCTCTGTCTCTCCCCTCAAGTCCACATCTGTTCTGTACATGCTAACCTTCAGGC
AATGCGCACTAAATTTTAAAGCAAGAAGCTCTTTCCTCCCATCAACCCACCAACCAGTTCTAGC
TTGCCCTTTCTCCATCAGCCCGCAAATAAAGCCCATGACCATGGAAAACAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_033838	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAB68844	(Get FASTA)	NCBI Sequence Viewer
	AAI27035	(Get FASTA)	NCBI Sequence Viewer
	AAI28476	(Get FASTA)	NCBI Sequence Viewer
	AAI39331	(Get FASTA)	NCBI Sequence Viewer
	AAI39332	(Get FASTA)	NCBI Sequence Viewer
	BAA76545	(Get FASTA)	NCBI Sequence Viewer
	BAC36087	(Get FASTA)	NCBI Sequence Viewer
	CAI61865	(Get FASTA)	NCBI Sequence Viewer
	EDL34050	(Get FASTA)	NCBI Sequence Viewer
	EDL34051	(Get FASTA)	NCBI Sequence Viewer
	EDL34052	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000001347
	ENSMUSP00000001347.7
GenBank Protein	Q9QYM5	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_033838 ⟸ NM_009708

- UniProtKB:

O35279 (UniProtKB/Swiss-Prot), Q9QYM5 (UniProtKB/Swiss-Prot), A2A4Q3 (UniProtKB/TrEMBL), A2VCR8 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MEGQSGRCKIVVVGDAECGKTALLQVFAKDAYPGSYVPTVFENYTASFEIDKRRIELNMWDTSG
SSYYDNVRPLAYPDSDAVLICFDISRPETLDSVLKKWQGETQEFCPNAKVVLVGCKLDMRTDLA
TLRELSKQRLIPVTHEQGTVLAKQVGAVSYVECSSRSSERSVRDVFHVATVASLGRGHRQLRRT
DSRRGLQRSTQLSGRPDRGNEGEMHKDRAKSCNLM

hide sequence

Ensembl Acc Id:

ENSMUSP00000001347 ⟸ ENSMUST00000001347

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9QYM5-F1-model_v2	AlphaFold	Q9QYM5	1-227	view protein structure

Promoters

RGD ID:

6821733

Promoter ID:

MM_KWN:9898

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

3T3L1_Day0, BoneMarrow_0Hour, BoneMarrow_2Hour, BoneMarrow_4Hour, Brain, ES_Cell, Lung, MEF_B4, MEF_B6

Transcripts:

OTTMUST00000005893, OTTMUST00000005894

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	11	101,325,446 - 101,326,767 (+)	MPROMDB

RGD ID:

6821735

Promoter ID:

MM_KWN:9900

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

Brain, Liver

Transcripts:

OTTMUST00000005892

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	11	101,329,056 - 101,329,556 (+)	MPROMDB

RGD ID:

8676808

Promoter ID:

EPDNEW_M16433

Type:

single initiation site

Name:

Rnd2_2

Description:

Mus musculus Rho family GTPase 2 , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_M16435

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	11	101,465,042 - 101,465,102	EPDNEW

RGD ID:

8676810

Promoter ID:

EPDNEW_M16435

Type:

initiation region

Name:

Rnd2_1

Description:

Mus musculus Rho family GTPase 2 , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_M16433

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	11	101,468,219 - 101,468,279	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:1338755	AgrOrtholog
Ensembl Genes	ENSMUSG00000001313	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSMUST00000001347	ENTREZGENE
	ENSMUST00000001347.7	UniProtKB/Swiss-Prot
Gene3D-CATH	3.40.50.300	UniProtKB/Swiss-Prot
InterPro	P-loop_NTPase	UniProtKB/Swiss-Prot
	RhoN	UniProtKB/Swiss-Prot
	Small_GTP-bd_dom	UniProtKB/Swiss-Prot
	Small_GTPase	UniProtKB/Swiss-Prot
	Small_GTPase_Rho	UniProtKB/Swiss-Prot
KEGG Report	mmu:11858	UniProtKB/Swiss-Prot
MGD	MGI:1338755	ENTREZGENE
NCBI Gene	11858	ENTREZGENE
PANTHER	PTHR24072	UniProtKB/Swiss-Prot
Pfam	Ras	UniProtKB/Swiss-Prot
PhenoGen	Rnd2	PhenoGen
PRINTS	RASTRNSFRMNG	UniProtKB/Swiss-Prot
PROSITE	RHO	UniProtKB/Swiss-Prot
SMART	RAB	UniProtKB/Swiss-Prot
	RAS	UniProtKB/Swiss-Prot
	RHO	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF52540	UniProtKB/Swiss-Prot
UniProt	A1L0U2_MOUSE	UniProtKB/TrEMBL
	A2A4Q3	ENTREZGENE, UniProtKB/TrEMBL
	A2VCR8	ENTREZGENE, UniProtKB/TrEMBL
	O35279	ENTREZGENE
	Q9QYM5	ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary	O35279	UniProtKB/Swiss-Prot

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar

Mammalian Phenotype