Chrd (chordin) - Rat Genome Database

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Gene: Chrd (chordin) Mus musculus
Analyze
Symbol: Chrd
Name: chordin
RGD ID: 1550370
MGI Page MGI
Description: Enables BMP binding activity; heparin binding activity; and proteoglycan binding activity. Involved in several processes, including cell surface receptor signaling pathway; circulatory system development; and modulation of chemical synaptic transmission. Acts upstream of or within several processes, including gastrulation; negative regulation of osteoblast differentiation; and osteoblast differentiation. Located in extracellular space. Is active in cell surface and extracellular region. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; genitourinary system; and skeletal system. Used to study DiGeorge syndrome and velocardiofacial syndrome. Orthologous to human CHRD (chordin).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Chd
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391620,551,528 - 20,561,132 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1620,551,877 - 20,561,134 (+)EnsemblGRCm39 Ensembl
GRCm381620,731,425 - 20,742,384 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1620,733,127 - 20,742,384 (+)EnsemblGRCm38mm10GRCm38
MGSCv371620,733,200 - 20,742,457 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361620,646,670 - 20,655,925 (+)NCBIMGSCv36mm8
Celera1621,298,477 - 21,307,717 (+)NCBICelera
Cytogenetic Map16B1NCBI
cM Map1612.51NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
artery morphogenesis  (IMP)
BMP signaling pathway  (IDA,IGI,IMP,ISO)
cell population proliferation  (IGI)
central nervous system development  (IMP)
chordate pharynx development  (IMP)
cranial skeletal system development  (IGI)
descending aorta development  (IMP)
dorsal/ventral pattern formation  (IBA,IMP)
embryonic axis specification  (IDA)
embryonic heart tube development  (IMP)
epithelial cell fate commitment  (IDA)
exploration behavior  (IMP)
fibroblast growth factor receptor signaling pathway  (IGI)
forebrain development  (IGI,IMP)
gastrulation with mouth forming second  (IMP)
gene expression  (IMP)
in utero embryonic development  (IMP)
long-term synaptic potentiation  (IMP)
maintenance of protein location  (IDA)
mesenchymal cell fate commitment  (IDA)
mesoderm formation  (IMP)
negative regulation of BMP signaling pathway  (IBA,IDA,ISO)
negative regulation of cell migration  (ISO)
negative regulation of osteoblast differentiation  (IDA,ISO)
neural crest formation  (IMP)
neuron fate commitment  (IDA)
osteoblast differentiation  (IDA)
pattern specification process  (IMP)
positive regulation of cell adhesion  (ISO)
positive regulation of mesenchymal cell proliferation  (ISO)
presynaptic modulation of chemical synaptic transmission  (IMP)
protein import  (IDA)
regulation of neuronal synaptic plasticity  (IMP)
short-term synaptic potentiation  (IMP)
skeletal system development  (IMP)
smoothened signaling pathway  (IGI)
spinal cord dorsal/ventral patterning  (ISO)
synapse organization  (IMP)
venous blood vessel morphogenesis  (IMP)
visual learning  (IMP)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal anterior definitive endoderm morphology  (IAGP)
abnormal aortic arch morphology  (IAGP)
abnormal artery morphology  (IAGP)
abnormal brachiocephalic trunk morphology  (IAGP)
abnormal brain development  (IAGP)
abnormal cardiovascular development  (IAGP)
abnormal cephalic neural fold morphology  (IAGP)
abnormal common carotid artery morphology  (IAGP)
abnormal cranial ganglia morphology  (IAGP)
abnormal diencephalon morphology  (IAGP)
abnormal direction of heart looping  (IAGP)
abnormal ear development  (IAGP)
abnormal ear position  (IAGP)
abnormal embryonic tissue morphology  (IAGP)
abnormal extraembryonic tissue morphology  (IAGP)
abnormal facial morphology  (IAGP)
abnormal forebrain development  (IAGP)
abnormal laryngeal cartilage morphology  (IAGP)
abnormal left-right axis patterning  (IAGP)
abnormal mandible morphology  (IAGP)
abnormal mesendoderm development  (IAGP)
abnormal mesoderm development  (IAGP)
abnormal middle ear morphology  (IAGP)
abnormal miniature excitatory postsynaptic currents  (IAGP)
abnormal neural crest cell migration  (IAGP)
abnormal neural plate morphology  (IAGP)
abnormal oropharynx morphology  (IAGP)
abnormal outer ear morphology  (IAGP)
abnormal pharyngeal arch artery morphology  (IAGP)
abnormal pharyngeal arch morphology  (IAGP)
abnormal pharyngeal pouch morphology  (IAGP)
abnormal prechordal plate morphology  (IAGP)
abnormal response to novel object  (IAGP)
abnormal secondary palate development  (IAGP)
abnormal skeleton morphology  (IAGP)
abnormal spatial learning  (IAGP)
abnormal telencephalon morphology  (IAGP)
abnormal thoracic vertebrae morphology  (IAGP)
abnormal thyroid gland morphology  (IAGP)
abnormal trigeminal ganglion morphology  (IAGP)
abnormal tympanic ring morphology  (IAGP)
abnormal vertebral arch development  (IAGP)
abnormal vertebral arch morphology  (IAGP)
abnormal vestibulocochlear ganglion morphology  (IAGP)
absent arcus anterior  (IAGP)
absent auditory tube  (IAGP)
absent esophagus  (IAGP)
absent inner ear  (IAGP)
absent mandible  (IAGP)
absent mandibular angle  (IAGP)
absent mandibular condyloid process  (IAGP)
absent mandibular coronoid process  (IAGP)
absent mesoderm  (IAGP)
absent nasal placodes  (IAGP)
absent nodose ganglion  (IAGP)
absent notochord  (IAGP)
absent parathyroid glands  (IAGP)
absent petrosal ganglion  (IAGP)
absent pharyngeal arches  (IAGP)
absent pulmonary trunk  (IAGP)
absent sclerotome  (IAGP)
absent somites  (IAGP)
absent temporal bone squamous part  (IAGP)
anophthalmia  (IAGP)
aprosencephaly  (IAGP)
athymia  (IAGP)
cleft palate  (IAGP)
cleft secondary palate  (IAGP)
cricoid cartilage hypoplasia  (IAGP)
cyanosis  (IAGP)
cyclopia  (IAGP)
decreased body size  (IAGP)
decreased embryo size  (IAGP)
decreased exploration in new environment  (IAGP)
decreased forebrain size  (IAGP)
decreased rib number  (IAGP)
decreased tympanic ring size  (IAGP)
embryonic lethality between somite formation and embryo turning, complete penetrance  (IAGP)
embryonic lethality between somite formation and embryo turning, incomplete penetrance  (IAGP)
embryonic lethality during organogenesis, incomplete penetrance  (IAGP)
enhanced long-term potentiation  (IAGP)
enhanced paired-pulse facilitation  (IAGP)
enlarged allantois  (IAGP)
fused first pharyngeal arch  (IAGP)
fusion of basioccipital and basisphenoid bone  (IAGP)
heart right ventricle hypertrophy  (IAGP)
hemorrhage  (IAGP)
holoprosencephaly  (IAGP)
hydrops fetalis  (IAGP)
hyoid bone hypoplasia  (IAGP)
hyperactivity  (IAGP)
increased neurotransmitter release  (IAGP)
increased vasodilation  (IAGP)
lethality throughout fetal growth and development, complete penetrance  (IAGP)
lethality throughout fetal growth and development, incomplete penetrance  (IAGP)
microcephaly  (IAGP)
no abnormal phenotype detected  (IAGP)
palatal shelves fail to meet at midline  (IAGP)
perinatal lethality  (IAGP)
perinatal lethality, complete penetrance  (IAGP)
perinatal lethality, incomplete penetrance  (IAGP)
persistent truncus arteriosus  (IAGP)
presphenoid bone hypoplasia  (IAGP)
proboscis  (IAGP)
retroesophageal right subclavian artery  (IAGP)
right aortic arch  (IAGP)
short mandible  (IAGP)
short zygomatic arch  (IAGP)
small ears  (IAGP)
small geniculate ganglion  (IAGP)
small mandible  (IAGP)
small nodose ganglion  (IAGP)
small otic capsule  (IAGP)
small otic vesicle  (IAGP)
small petrosal ganglion  (IAGP)
small pharynx  (IAGP)
small temporal bone  (IAGP)
small trachea  (IAGP)
small vertebral body  (IAGP)
thoracic vertebral transformation  (IAGP)
thyroid cartilage hypoplasia  (IAGP)
thyroid gland hypoplasia  (IAGP)
tracheoesophageal fistula  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. MGD IEA MGD IEA
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
6. Mouse MP Annotation Import Pipeline RGD automated import pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:9449667   PMID:9600941   PMID:9620855   PMID:9782094   PMID:10331975   PMID:10349636   PMID:10373301   PMID:10479448   PMID:10524628   PMID:10642791   PMID:10688202  
PMID:10767089   PMID:10769235   PMID:11042159   PMID:11076861   PMID:11118896   PMID:11217851   PMID:11260715   PMID:11291865   PMID:11306815   PMID:11401399   PMID:11532921   PMID:11566865  
PMID:11704830   PMID:11731460   PMID:11784076   PMID:11969257   PMID:12397106   PMID:12414734   PMID:12421925   PMID:12477932   PMID:12666204   PMID:12808086   PMID:12810603   PMID:12842913  
PMID:12915318   PMID:14502572   PMID:14504233   PMID:14516682   PMID:14681194   PMID:14681479   PMID:15013800   PMID:15084457   PMID:15217980   PMID:15371327   PMID:15381701   PMID:15780974  
PMID:16141072   PMID:16141073   PMID:16537572   PMID:16602821   PMID:16894609   PMID:16943282   PMID:17634368   PMID:17685487   PMID:17693602   PMID:18028901   PMID:18241853   PMID:18268105  
PMID:18287559   PMID:18403408   PMID:18550712   PMID:18617531   PMID:18789316   PMID:19247433   PMID:19389368   PMID:19615442   PMID:19850029   PMID:19852960   PMID:19914233   PMID:20450902  
PMID:20503368   PMID:20508035   PMID:20573697   PMID:20730911   PMID:20807528   PMID:20826531   PMID:21068065   PMID:21192082   PMID:21445260   PMID:21645366   PMID:21873635   PMID:22075149  
PMID:22076636   PMID:22302143   PMID:22560297   PMID:23103586   PMID:23213481   PMID:23313125   PMID:23475960   PMID:23552073   PMID:23918385   PMID:24514266   PMID:25977363   PMID:26534985  
PMID:26952187   PMID:28439006   PMID:29992973   PMID:31539501   PMID:31950080   PMID:32105677   PMID:34184034   PMID:36197846   PMID:36916392  


Genomics

Comparative Map Data
Chrd
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391620,551,528 - 20,561,132 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1620,551,877 - 20,561,134 (+)EnsemblGRCm39 Ensembl
GRCm381620,731,425 - 20,742,384 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1620,733,127 - 20,742,384 (+)EnsemblGRCm38mm10GRCm38
MGSCv371620,733,200 - 20,742,457 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361620,646,670 - 20,655,925 (+)NCBIMGSCv36mm8
Celera1621,298,477 - 21,307,717 (+)NCBICelera
Cytogenetic Map16B1NCBI
cM Map1612.51NCBI
CHRD
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383184,380,054 - 184,390,739 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3184,380,054 - 184,390,736 (+)EnsemblGRCh38hg38GRCh38
GRCh373184,097,842 - 184,108,527 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363185,580,555 - 185,590,311 (+)NCBINCBI36Build 36hg18NCBI36
Build 343185,580,562 - 185,590,320NCBI
Celera3182,538,936 - 182,548,675 (+)NCBICelera
Cytogenetic Map3q27.1NCBI
HuRef3181,483,159 - 181,513,643 (+)NCBIHuRef
CHM1_13184,062,275 - 184,072,053 (+)NCBICHM1_1
T2T-CHM13v2.03187,189,309 - 187,199,979 (+)NCBIT2T-CHM13v2.0
Chrd
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81193,676,400 - 93,685,584 (-)NCBIGRCr8
mRatBN7.21180,171,994 - 80,181,166 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1180,171,994 - 80,180,673 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1188,894,706 - 88,903,406 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01181,548,122 - 81,556,822 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01180,609,184 - 80,617,884 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01183,858,503 - 83,867,543 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1183,858,503 - 83,867,203 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01186,930,421 - 86,939,186 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41182,401,701 - 82,410,401 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11182,460,992 - 82,462,358 (-)NCBI
Celera1179,011,743 - 79,020,443 (-)NCBICelera
Cytogenetic Map11q23NCBI
Chrd
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542023,112,093 - 23,120,036 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542023,111,690 - 23,120,038 (-)NCBIChiLan1.0ChiLan1.0
CHRD
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22182,252,887 - 182,262,820 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13182,257,731 - 182,267,537 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03181,417,140 - 181,460,236 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13189,899,342 - 189,908,573 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3189,898,856 - 189,908,573 (+)Ensemblpanpan1.1panPan2
CHRD
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13417,255,770 - 17,264,776 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3417,255,562 - 17,271,713 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3421,341,312 - 21,350,291 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03417,163,252 - 17,172,231 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3417,163,252 - 17,171,973 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13417,200,125 - 17,209,104 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03417,196,194 - 17,205,174 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03417,425,160 - 17,434,173 (+)NCBIUU_Cfam_GSD_1.0
Chrd
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602119,406,169 - 119,415,345 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365785,498,887 - 5,507,198 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365785,498,473 - 5,507,195 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CHRD
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13122,266,626 - 122,277,645 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113122,266,632 - 122,277,513 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213131,758,103 - 131,767,009 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CHRD
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1155,030,618 - 5,040,399 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl155,030,457 - 5,039,991 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606313,808,558 - 13,818,236 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Chrd
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473072,201,644 - 72,209,843 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473072,201,239 - 72,209,843 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Chrd
241 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1586
Count of miRNA genes:651
Interacting mature miRNAs:835
Transcripts:ENSMUST00000007171, ENSMUST00000115423, ENSMUST00000151150, ENSMUST00000153299
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4141060Pbwg19_mpostnatal body weight growth 19 (mouse)Not determined16120780888Mouse
1300632Loca2_mlocomotor activity 2 (mouse)Not determined16122500574Mouse
10043879Adip25_madiposity 25 (mouse)Not determined16122520318Mouse
1301575Tanidd3_mtally ho associated non-insulin dependednt diabetes mellitus 3 (mouse)Not determined16122897739Mouse
4141468Nhdlq10_mnon-HDL QTL 10 (mouse)Not determined16124263853Mouse
1301970Heal11_mwound healing/regeneration 11 (mouse)Not determined16124263853Mouse
1301384Dice1_mdetermination of interleukin 4 commitment 1 (mouse)Not determined16128434358Mouse
10402497Lmr23_mleishmaniasis resistance 23 (mouse)Not determined16129674200Mouse
1301559Bbaa19_mB.burgdorferi-associated arthritis 19 (mouse)Not determined16130066977Mouse
10412289Ppsl_mplasma P-selectin levels (mouse)Not determined16130814572Mouse
27095908Scvln7_msacral vertebrae length 2, 5 week (mouse)16331786439820362Mouse
27226768Tibl9_mtibia length 9, 5 week (mouse)16331786451420363Mouse
27226785Feml12_mfemur length 12, 5 week (mouse)16331786464620363Mouse
26884432Zlq7_mzygomatic length QTL 7, 10 week (mouse)16381786464620363Mouse
38501069Tip4_mtuberculosis immunophenotype 4, IFN-g level (mouse)16431786444520363Mouse
1301443Mopkd2_mmodifier of polycystic kidney disease progression 2 (mouse)Not determined16464631438646414Mouse
1300656Bgeq15_mbody growth early QTL 15 (mouse)Not determined16577525239775440Mouse
1301945Skl7_mskeletal size (tail length) 7 (mouse)Not determined16577525239775440Mouse
1300943Skts9_mskin tumor susceptibility 9 (mouse)Not determined16577525239775440Mouse
1300987Skull23_mskull morphology 23 (mouse)Not determined16577525239775440Mouse
4141010Bbq1_mbrain and behavior QTL 1 (mouse)Not determined16647700935021216Mouse
1357763Lp1_mlymphocyte proliferation 1 (mouse)Not determined16654297965466552Mouse
4142460Nilac10_mnicotine induced locomotor activity 10 (mouse)Not determined16713690629225471Mouse
11251724Ewc6_methanol withdrawal and consumption 6 (mouse)16822605242226052Mouse
26884376Skwq4_mskull length QTL 4, 5 week (mouse)16841786490896888Mouse
10043978Obq35_mobesity QTL 35 (mouse)Not determined16988163143881631Mouse
1301086Lprm5_mlymphoproliferation modifier 5 (mouse)Not determined161184882445848923Mouse
1301841Lrnx9_mlearning-contextual 9 (mouse)Not determined161222536046225471Mouse
10045614Rapop6_mradiation-induced apoptosis 6 (mouse)Not determined161480292148803032Mouse
4142236Pstc4_mperiosteal circumference 4 (mouse)Not determined161552290949523112Mouse
11565820Vasr1_mvariability in acoustic startle response 1 (mouse)161969865726368664Mouse
1357517Bwtn1_mbody weight at necropsy 1 (mouse)Not determined162001932985600826Mouse

Markers in Region
Chrd  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381620,734,329 - 20,734,725UniSTSGRCm38
MGSCv371620,734,402 - 20,734,798UniSTSGRCm37
Celera1621,299,679 - 21,300,075UniSTS
Cytogenetic Map16B1UniSTS
cM Map1614.0UniSTS
MARC_16893-16894:1020710585:1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381620,736,307 - 20,736,961UniSTSGRCm38
MGSCv371620,736,380 - 20,737,034UniSTSGRCm37
Celera1621,301,657 - 21,302,311UniSTS
Cytogenetic Map16B1UniSTS
cM Map1614.0UniSTS
Chrd  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16B1UniSTS
cM Map1614.0UniSTS
Chrd  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16B1UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001278041 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001354995 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001354996 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001416766 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_009893 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_184392 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006521745 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011245814 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011245815 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011245816 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011245817 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017316861 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030248947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030248950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036159761 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036159762 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036159763 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001781784 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_003951745 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004939151 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004939152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004939153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_875721 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF069501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF096276 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI838093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK077460 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK149445 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK165339 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK220310 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC145017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC145018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC145019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC145696 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466521 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT010490 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000007171   ⟹   ENSMUSP00000007171
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1620,551,877 - 20,561,134 (+)Ensembl
GRCm38.p6 Ensembl1620,733,127 - 20,742,384 (+)Ensembl
RefSeq Acc Id: ENSMUST00000115423   ⟹   ENSMUSP00000111083
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1620,551,877 - 20,556,902 (+)Ensembl
GRCm38.p6 Ensembl1620,733,127 - 20,738,152 (+)Ensembl
RefSeq Acc Id: ENSMUST00000151150
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1620,554,956 - 20,561,132 (+)Ensembl
GRCm38.p6 Ensembl1620,736,206 - 20,742,382 (+)Ensembl
RefSeq Acc Id: ENSMUST00000153299   ⟹   ENSMUSP00000138259
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1620,551,877 - 20,561,134 (+)Ensembl
GRCm38.p6 Ensembl1620,733,127 - 20,742,384 (+)Ensembl
RefSeq Acc Id: ENSMUST00000231636   ⟹   ENSMUSP00000156160
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1620,551,879 - 20,560,871 (+)Ensembl
GRCm38.p6 Ensembl1620,733,129 - 20,742,121 (+)Ensembl
RefSeq Acc Id: ENSMUST00000231689
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1620,552,253 - 20,553,331 (+)Ensembl
GRCm38.p6 Ensembl1620,733,503 - 20,734,581 (+)Ensembl
RefSeq Acc Id: ENSMUST00000231698   ⟹   ENSMUSP00000156323
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1620,551,879 - 20,560,871 (+)Ensembl
GRCm38.p6 Ensembl1620,733,129 - 20,742,121 (+)Ensembl
RefSeq Acc Id: ENSMUST00000232020
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1620,552,184 - 20,553,657 (+)Ensembl
GRCm38.p6 Ensembl1620,733,434 - 20,734,907 (+)Ensembl
RefSeq Acc Id: ENSMUST00000232104
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1620,551,879 - 20,560,871 (+)Ensembl
GRCm38.p6 Ensembl1620,733,129 - 20,742,121 (+)Ensembl
RefSeq Acc Id: ENSMUST00000232646   ⟹   ENSMUSP00000156080
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1620,551,879 - 20,560,871 (+)Ensembl
GRCm38.p6 Ensembl1620,733,129 - 20,742,121 (+)Ensembl
RefSeq Acc Id: NM_001278041   ⟹   NP_001264970
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391620,551,880 - 20,561,132 (+)NCBI
GRCm381620,733,127 - 20,742,384 (+)NCBI
Celera1621,298,477 - 21,307,717 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001354995   ⟹   NP_001341924
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391620,551,880 - 20,561,132 (+)NCBI
GRCm381620,733,127 - 20,742,384 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001354996   ⟹   NP_001341925
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391620,551,880 - 20,561,132 (+)NCBI
GRCm381620,733,127 - 20,742,384 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001416766   ⟹   NP_001403695
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391620,551,880 - 20,561,132 (+)NCBI
RefSeq Acc Id: NM_009893   ⟹   NP_034023
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391620,551,880 - 20,561,132 (+)NCBI
GRCm381620,733,127 - 20,742,384 (+)NCBI
MGSCv371620,733,200 - 20,742,457 (+)RGD
Celera1621,298,477 - 21,307,717 (+)RGD
cM Map16 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_184392
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391620,551,880 - 20,561,132 (+)NCBI
RefSeq Acc Id: XM_006521745   ⟹   XP_006521808
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391620,551,541 - 20,561,132 (+)NCBI
GRCm381620,733,050 - 20,742,382 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011245814   ⟹   XP_011244116
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391620,551,541 - 20,561,132 (+)NCBI
GRCm381620,733,050 - 20,742,382 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011245815   ⟹   XP_011244117
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391620,551,541 - 20,561,132 (+)NCBI
GRCm381620,733,050 - 20,742,382 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011245816   ⟹   XP_011244118
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391620,551,541 - 20,561,132 (+)NCBI
GRCm381620,733,050 - 20,742,382 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011245817   ⟹   XP_011244119
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391620,551,528 - 20,561,132 (+)NCBI
GRCm381620,731,425 - 20,742,382 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017316861   ⟹   XP_017172350
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391620,553,436 - 20,561,132 (+)NCBI
GRCm381620,734,686 - 20,742,382 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030248947   ⟹   XP_030104807
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391620,551,528 - 20,561,132 (+)NCBI
GRCm381620,731,425 - 20,742,382 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030248950   ⟹   XP_030104810
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391620,551,957 - 20,561,132 (+)NCBI
GRCm381620,733,501 - 20,742,382 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036159761   ⟹   XP_036015654
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391620,551,541 - 20,561,132 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036159762   ⟹   XP_036015655
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391620,551,956 - 20,561,132 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036159763   ⟹   XP_036015656
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391620,551,868 - 20,561,132 (+)NCBI
Sequence:
RefSeq Acc Id: XR_001781784
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391620,551,541 - 20,557,747 (+)NCBI
GRCm381620,733,050 - 20,738,997 (+)NCBI
Sequence:
RefSeq Acc Id: XR_003951745
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391620,551,541 - 20,561,132 (+)NCBI
GRCm381620,733,050 - 20,742,382 (+)NCBI
Sequence:
RefSeq Acc Id: XR_004939151
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391620,551,528 - 20,561,132 (+)NCBI
Sequence:
RefSeq Acc Id: XR_004939152
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391620,551,541 - 20,561,132 (+)NCBI
Sequence:
RefSeq Acc Id: XR_004939153
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391620,551,541 - 20,561,132 (+)NCBI
Sequence:
RefSeq Acc Id: XR_875721
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391620,551,541 - 20,561,132 (+)NCBI
GRCm381620,733,050 - 20,742,382 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001264970 (Get FASTA)   NCBI Sequence Viewer  
  NP_001341924 (Get FASTA)   NCBI Sequence Viewer  
  NP_001341925 (Get FASTA)   NCBI Sequence Viewer  
  NP_001403695 (Get FASTA)   NCBI Sequence Viewer  
  NP_034023 (Get FASTA)   NCBI Sequence Viewer  
  XP_006521808 (Get FASTA)   NCBI Sequence Viewer  
  XP_011244116 (Get FASTA)   NCBI Sequence Viewer  
  XP_011244117 (Get FASTA)   NCBI Sequence Viewer  
  XP_011244118 (Get FASTA)   NCBI Sequence Viewer  
  XP_011244119 (Get FASTA)   NCBI Sequence Viewer  
  XP_017172350 (Get FASTA)   NCBI Sequence Viewer  
  XP_030104807 (Get FASTA)   NCBI Sequence Viewer  
  XP_030104810 (Get FASTA)   NCBI Sequence Viewer  
  XP_036015654 (Get FASTA)   NCBI Sequence Viewer  
  XP_036015655 (Get FASTA)   NCBI Sequence Viewer  
  XP_036015656 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC68867 (Get FASTA)   NCBI Sequence Viewer  
  AAD19895 (Get FASTA)   NCBI Sequence Viewer  
  AAI45697 (Get FASTA)   NCBI Sequence Viewer  
  BAD90387 (Get FASTA)   NCBI Sequence Viewer  
  BAE28881 (Get FASTA)   NCBI Sequence Viewer  
  EDK97595 (Get FASTA)   NCBI Sequence Viewer  
  EDK97596 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000007171
  ENSMUSP00000007171.7
  ENSMUSP00000111083.2
  ENSMUSP00000138259.2
  ENSMUSP00000156080
  ENSMUSP00000156080.2
  ENSMUSP00000156160.2
  ENSMUSP00000156323.2
GenBank Protein Q9Z0E2 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_034023   ⟸   NM_009893
- Peptide Label: isoform 1 precursor
- UniProtKB: Q9Z0E2 (UniProtKB/Swiss-Prot),   Q3UEN0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001264970   ⟸   NM_001278041
- Peptide Label: isoform 2 precursor
- UniProtKB: A6H5Z6 (UniProtKB/TrEMBL),   Q3UEN0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006521808   ⟸   XM_006521745
- Peptide Label: isoform X5
- UniProtKB: Q3UEN0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011244118   ⟸   XM_011245816
- Peptide Label: isoform X3
- UniProtKB: Q3UEN0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011244116   ⟸   XM_011245814
- Peptide Label: isoform X1
- UniProtKB: Q3UEN0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011244117   ⟸   XM_011245815
- Peptide Label: isoform X2
- UniProtKB: Q3UEN0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011244119   ⟸   XM_011245817
- Peptide Label: isoform X6
- UniProtKB: Q3UEN0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017172350   ⟸   XM_017316861
- Peptide Label: isoform X9
- Sequence:
RefSeq Acc Id: XP_030104807   ⟸   XM_030248947
- Peptide Label: isoform X7
- UniProtKB: Q3UEN0 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001341924   ⟸   NM_001354995
- Peptide Label: isoform 3
RefSeq Acc Id: NP_001341925   ⟸   NM_001354996
- Peptide Label: isoform 4 precursor
- UniProtKB: Q3UEN0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030104810   ⟸   XM_030248950
- Peptide Label: isoform X11
RefSeq Acc Id: ENSMUSP00000007171   ⟸   ENSMUST00000007171
RefSeq Acc Id: ENSMUSP00000156160   ⟸   ENSMUST00000231636
RefSeq Acc Id: ENSMUSP00000156323   ⟸   ENSMUST00000231698
RefSeq Acc Id: ENSMUSP00000111083   ⟸   ENSMUST00000115423
RefSeq Acc Id: ENSMUSP00000156080   ⟸   ENSMUST00000232646
RefSeq Acc Id: ENSMUSP00000138259   ⟸   ENSMUST00000153299
RefSeq Acc Id: XP_036015654   ⟸   XM_036159761
- Peptide Label: isoform X4
- UniProtKB: Q3UEN0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_036015656   ⟸   XM_036159763
- Peptide Label: isoform X10
RefSeq Acc Id: XP_036015655   ⟸   XM_036159762
- Peptide Label: isoform X10
RefSeq Acc Id: NP_001403695   ⟸   NM_001416766
- Peptide Label: isoform 5 precursor
- UniProtKB: Q3UEN0 (UniProtKB/TrEMBL)
Protein Domains
CHRD   VWFC

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9Z0E2-F1-model_v2 AlphaFold Q9Z0E2 1-948 view protein structure

Promoters
RGD ID:8685776
Promoter ID:EPDNEW_M20919
Type:initiation region
Name:Chrd_1
Description:Mus musculus chordin , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381620,733,134 - 20,733,194EPDNEW
RGD ID:6826908
Promoter ID:MM_KWN:20505
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:OTTMUST00000049690
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361620,737,186 - 20,738,287 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1313268 AgrOrtholog
Ensembl Genes ENSMUSG00000006958 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000007171 ENTREZGENE
  ENSMUST00000007171.13 UniProtKB/Swiss-Prot
  ENSMUST00000115423.8 UniProtKB/TrEMBL
  ENSMUST00000153299 ENTREZGENE
  ENSMUST00000153299.8 UniProtKB/TrEMBL
  ENSMUST00000231636.2 UniProtKB/TrEMBL
  ENSMUST00000231698.2 UniProtKB/TrEMBL
  ENSMUST00000232646 ENTREZGENE
  ENSMUST00000232646.2 UniProtKB/TrEMBL
Gene3D-CATH 6.20.200.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Chordin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CHRD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VWF_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:12667 UniProtKB/Swiss-Prot
MGD MGI:1313268 ENTREZGENE
NCBI Gene 12667 ENTREZGENE
PANTHER CHORDIN UniProtKB/Swiss-Prot
  CHORDIN UniProtKB/Swiss-Prot
  CHORDIN UniProtKB/TrEMBL
  CHORDIN UniProtKB/TrEMBL
Pfam CHRD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VWC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Chrd PhenoGen
PIRSF Chordin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE CHRD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VWFC_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VWFC_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART CHRD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VWC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP FnI-like domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A338P7C1_MOUSE UniProtKB/TrEMBL
  A2CG33_MOUSE UniProtKB/TrEMBL
  A6H5Z6 ENTREZGENE, UniProtKB/TrEMBL
  CHRD_MOUSE UniProtKB/Swiss-Prot
  Q3UEN0 ENTREZGENE, UniProtKB/TrEMBL
  Q5DU60_MOUSE UniProtKB/TrEMBL
  Q9Z0E2 ENTREZGENE
  S4R1K6_MOUSE UniProtKB/TrEMBL