Cd2ap (CD2-associated protein) - Rat Genome Database

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Gene: Cd2ap (CD2-associated protein) Mus musculus
Analyze
Symbol: Cd2ap
Name: CD2-associated protein
RGD ID: 1550249
MGI Page MGI
Description: Enables actin filament binding activity; clathrin binding activity; and phosphatidylinositol 3-kinase regulatory subunit binding activity. Involved in synapse organization. Acts upstream of or within several processes, including cell surface receptor signaling pathway; intracellular signaling cassette; and plasma membrane bounded cell projection organization. Located in several cellular components, including axon; cell-cell junction; and dendrite. Part of protein-containing complex. Is active in several cellular components, including actin cytoskeleton; nuclear envelope lumen; and slit diaphragm. Is expressed in several structures, including alimentary system; blastocyst; early embryo; genitourinary system; and lung. Used to study end stage renal disease and focal segmental glomerulosclerosis 3. Human ortholog(s) of this gene implicated in focal segmental glomerulosclerosis and focal segmental glomerulosclerosis 3. Orthologous to human CD2AP (CD2 associated protein).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AL024079; C78928; mesenchyme to epithelium transition protein, SH3 domains; mesenchyme-to-epithelium transition protein with SH3 domains 1; Mets; METS-; METS-1; Mets1; SH3 domain-containing adapter protein; SH3 domain-containing adaptor protein METS-1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Gm6475   Gm7529  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391743,059,857 - 43,187,593 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1743,103,842 - 43,187,556 (-)EnsemblGRCm39 Ensembl
GRCm381742,748,887 - 42,876,707 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1742,792,951 - 42,876,665 (-)EnsemblGRCm38mm10GRCm38
MGSCv371742,929,900 - 43,013,373 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361742,256,435 - 42,352,155 (-)NCBIMGSCv36mm8
Celera1746,201,889 - 46,261,450 (-)NCBICelera
Cytogenetic Map17B3NCBI
cM Map1719.67NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (ISO)
3-chloropropane-1,2-diol  (ISO)
6-propyl-2-thiouracil  (ISO)
acrylamide  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
amphetamine  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (EXP)
bisphenol A  (EXP,ISO)
cadmium atom  (EXP)
cadmium dichloride  (EXP)
caffeine  (ISO)
carbamazepine  (ISO)
celecoxib  (ISO)
chlordecone  (EXP)
cisplatin  (EXP)
cobalt dichloride  (ISO)
cyclosporin A  (EXP)
DDT  (ISO)
doxorubicin  (ISO)
enzyme inhibitor  (ISO)
FR900359  (ISO)
gentamycin  (ISO)
hydrogen cyanide  (EXP)
hydrogen peroxide  (EXP)
ivermectin  (ISO)
lisinopril dihydrate  (ISO)
methimazole  (ISO)
methylmercury chloride  (ISO)
microcystin-LR  (EXP)
N-nitrosodiethylamine  (EXP)
oxidopamine  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (EXP,ISO)
potassium chromate  (ISO)
potassium cyanide  (EXP)
prednisone  (ISO)
puromycin  (EXP)
quercetin  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
simvastatin  (ISO)
sodium arsenate  (EXP)
sulfadimethoxine  (ISO)
tetrachloromethane  (EXP,ISO)
thapsigargin  (ISO)
thioacetamide  (ISO)
thiram  (ISO)
titanium dioxide  (EXP)
triphenyl phosphate  (ISO)
vinclozolin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
actin filament organization  (IBA,ISO,ISS)
actin filament polymerization  (IMP)
adipose tissue development  (IDA)
apoptotic process  (IGI,IMP)
cell differentiation  (IGI)
cell division  (IEA)
cell migration  (IBA,ISO)
cell population proliferation  (IMP)
cell-cell adhesion  (ISO)
cell-cell adhesion mediated by cadherin  (IGI)
cell-cell junction organization  (IGI,IMP)
collateral sprouting  (IMP)
D-glucose import  (IMP)
endothelium development  (IMP)
ERK1 and ERK2 cascade  (IGI)
filopodium assembly  (IMP)
gene expression  (IGI,IMP)
glomerulus development  (IMP)
immunological synapse formation  (IMP)
inflammatory response  (IMP)
kidney development  (IDA,IMP)
lipid metabolic process  (IDA)
liver development  (IDA)
localization of cell  (IGI)
lymph node development  (IMP)
maintenance of blood-brain barrier  (IMP)
male gonad development  (IMP)
membrane organization  (IMP)
negative regulation of neuron apoptotic process  (IDA)
negative regulation of small GTPase mediated signal transduction  (ISO,ISS)
negative regulation of transforming growth factor beta1 production  (IGI)
nerve growth factor signaling pathway  (IMP)
neuron projection development  (IMP)
neurotrophin signaling pathway  (IMP)
neurotrophin TRK receptor signaling pathway  (IMP)
phosphatidylinositol 3-kinase/protein kinase B signal transduction  (IGI,IMP)
podocyte differentiation  (IMP)
positive regulation of protein localization to nucleus  (IGI)
positive regulation of protein secretion  (IEA,ISO)
proteasome-mediated ubiquitin-dependent protein catabolic process  (ISO)
protein catabolic process  (IDA,IMP)
protein heterooligomerization  (IDA)
protein phosphorylation  (IMP)
protein secretion  (IMP)
protein transport  (IMP)
Rab protein signal transduction  (IMP)
regulation of actin cytoskeleton organization  (IGI)
regulation of receptor-mediated endocytosis  (ISO)
regulation of synaptic plasticity  (IMP)
renal albumin absorption  (IMP)
response to glial cell derived neurotrophic factor  (IDA)
response to insulin  (IMP)
response to oxidative stress  (IMP)
response to transforming growth factor beta  (IMP)
response to virus  (IDA)
response to wounding  (IMP)
stress-activated MAPK cascade  (IMP)
synapse organization  (IDA,IEP,IMP)
T cell receptor signaling pathway  (IMP)
transforming growth factor beta1 production  (IGI)
vesicle organization  (ISO)

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. CD2-associated protein haploinsufficiency is linked to glomerular disease susceptibility. Kim JM, etal., Science. 2003 May 23;300(5623):1298-300.
3. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. MGD IEA MGD IEA
6. CD2AP expression in a renal ischemia/reperfusion injury model and analysis of its related genes using overexpression and RNA interference technique. Nishimura S, etal., Am J Nephrol. 2005 Jul-Aug;25(4):373-81. Epub 2005 Jun 25.
7. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
8. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
9. Mouse MP Annotation Import Pipeline RGD automated import pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7671812   PMID:9365514   PMID:9741631   PMID:10349636   PMID:10514378   PMID:10913159   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11544199   PMID:11733379   PMID:11733557  
PMID:12217315   PMID:12217865   PMID:12397035   PMID:12477932   PMID:12520002   PMID:12559036   PMID:12904583   PMID:14512504   PMID:14610273   PMID:14623103   PMID:14701729   PMID:15001553  
PMID:15213232   PMID:15331416   PMID:15489334   PMID:15782199   PMID:15924139   PMID:15951437   PMID:15956777   PMID:15965785   PMID:16141072   PMID:16141073   PMID:16319116   PMID:16498405  
PMID:16501493   PMID:16628251   PMID:16672319   PMID:16886065   PMID:17056598   PMID:17213204   PMID:17283187   PMID:17606992   PMID:17967808   PMID:18046313   PMID:18177421   PMID:18287559  
PMID:18328474   PMID:18554416   PMID:18753381   PMID:19013146   PMID:19306938   PMID:19334288   PMID:19679673   PMID:20360068   PMID:20457601   PMID:20576809   PMID:21267068   PMID:21406566  
PMID:21677750   PMID:21799297   PMID:21873635   PMID:21911934   PMID:22203040   PMID:22809625   PMID:22922362   PMID:23090967   PMID:23793062   PMID:24140342   PMID:24218450   PMID:24376653  
PMID:24425877   PMID:24598802   PMID:25730372   PMID:25887956   PMID:25962121   PMID:25968128   PMID:25993318   PMID:26073036   PMID:26076477   PMID:26142281   PMID:26358779   PMID:26496610  
PMID:26546360   PMID:26901816   PMID:27076424   PMID:27335373   PMID:27441654   PMID:27474268   PMID:27531950   PMID:27575556   PMID:27590856   PMID:27895104   PMID:28814739   PMID:28878342  
PMID:28916834   PMID:29729186   PMID:30612599   PMID:30723173   PMID:31062503   PMID:31412248   PMID:31461442   PMID:31878951   PMID:32325033   PMID:32552912   PMID:32554809   PMID:38310234  
PMID:38355793  


Genomics

Comparative Map Data
Cd2ap
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391743,059,857 - 43,187,593 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1743,103,842 - 43,187,556 (-)EnsemblGRCm39 Ensembl
GRCm381742,748,887 - 42,876,707 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1742,792,951 - 42,876,665 (-)EnsemblGRCm38mm10GRCm38
MGSCv371742,929,900 - 43,013,373 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361742,256,435 - 42,352,155 (-)NCBIMGSCv36mm8
Celera1746,201,889 - 46,261,450 (-)NCBICelera
Cytogenetic Map17B3NCBI
cM Map1719.67NCBI
CD2AP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38647,477,789 - 47,627,263 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl647,477,789 - 47,627,263 (+)EnsemblGRCh38hg38GRCh38
GRCh37647,445,525 - 47,594,999 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36647,553,484 - 47,702,958 (+)NCBINCBI36Build 36hg18NCBI36
Build 34647,553,898 - 47,702,606NCBI
Celera649,001,627 - 49,151,084 (+)NCBICelera
Cytogenetic Map6p12.3NCBI
HuRef647,172,874 - 47,322,780 (+)NCBIHuRef
CHM1_1647,448,327 - 47,597,835 (+)NCBICHM1_1
T2T-CHM13v2.0647,318,653 - 47,468,952 (+)NCBIT2T-CHM13v2.0
Cd2ap
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8925,580,071 - 25,679,968 (+)NCBIGRCr8
mRatBN7.2918,086,744 - 18,182,744 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl918,086,984 - 18,182,199 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx926,673,658 - 26,770,708 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0931,748,203 - 31,845,260 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0930,039,092 - 30,134,950 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0920,794,680 - 20,858,438 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl920,765,296 - 20,858,504 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0919,659,503 - 19,720,953 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4913,827,015 - 13,888,338 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1913,824,339 - 13,885,656 (+)NCBI
Celera915,825,287 - 15,886,480 (+)NCBICelera
Cytogenetic Map9q13NCBI
Cd2ap
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543711,983,311 - 12,091,100 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543712,005,399 - 12,087,014 (+)NCBIChiLan1.0ChiLan1.0
CD2AP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2561,977,062 - 62,123,354 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1657,844,128 - 57,989,578 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0647,065,284 - 47,210,746 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1648,328,836 - 48,474,166 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl648,328,863 - 48,474,163 (+)Ensemblpanpan1.1panPan2
CD2AP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11215,538,215 - 15,683,619 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1215,538,356 - 15,681,011 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1215,569,237 - 15,714,616 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01216,041,717 - 16,186,523 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1216,041,451 - 16,186,100 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11215,549,899 - 15,695,706 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01215,642,957 - 15,788,194 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01215,789,659 - 15,935,714 (+)NCBIUU_Cfam_GSD_1.0
Cd2ap
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494650,972,198 - 51,069,620 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647612,890,468 - 12,987,843 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647612,890,595 - 12,989,046 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CD2AP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl742,218,290 - 42,332,518 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1742,218,016 - 42,332,523 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2748,870,223 - 48,952,250 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CD2AP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11724,664,245 - 24,815,786 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1724,663,872 - 24,815,829 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604447,487,056 - 47,639,257 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cd2ap
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475413,420,603 - 13,511,523 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475413,420,594 - 13,511,672 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cd2ap
5409 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:837
Count of miRNA genes:514
Interacting mature miRNAs:600
Transcripts:ENSMUST00000024709
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10045977Tir9_mtrypanosome infection response 9 (mouse)Not determined172787811943885114Mouse
26884379Skwq5_mskull length QTL 5, 5 week (mouse)173311897454107028Mouse
1300885Mbis4_mMycobacterium bovis-induced systemic lupus erythematosus 4 (mouse)Not determined173517581770165926Mouse
1300890Bhr3_mbronchial hyperresponsiveness 3 (mouse)Not determined17397489048866091Mouse
11075105Modc1_mmodifier of Odc1 (mouse)172771579245622654Mouse
1300995Fembrs4_mfemur breaking strength 4 (mouse)Not determined171506165249061760Mouse
15039348Nmrs37_mNAFLD-associated magnetic resonance shift 37 (mouse)172781520961815209Mouse
4141357Mrdq1_mmodifier of retinal degeneration QTL 1 (mouse)Not determined3098790348039703Mouse
4141478Hbnr7_mHeligmosomoides bakeri nematode resistance 7 (mouse)Not determined4305118551739122Mouse
1302152Skull25_mskull morphology 25 (mouse)Not determined171681972150819843Mouse
10755514Amzn2_manatomical modifier of Zfp423 2 (mouse)173596629469966424Mouse
1302028Asbb3_mautoimmune susceptibility in C57BL/6J and BALB/c 3 (mouse)Not determined171087811944878219Mouse
15039354Nmrs36_mNAFLD-associated magnetic resonance shift 36 (mouse)171914502553145025Mouse
4141215Mnic1_mmacronutrient intake, carbohydrate 1 (mouse)Not determined485475245670266Mouse
13524847Asrq8a_macoustic startle response 8a (mouse)171264696146646961Mouse
1300914Pcir4_mperiosteal circumference 4 (mouse)Not determined171506165249061760Mouse
13452396Leusq3_mleucocytosis susceptibility QTL 3 (mouse)171746220851462345Mouse
13452399Leusq6_mleucocytosis susceptibility QTL 6 (mouse)171746220851462345Mouse
1300535Char3_mP. chabaudi malaria resistance QTL 3 (mouse)Not determined171746220851462345Mouse
4140955Plgr1_mplague resistance locus 1 (mouse)Not determined3103350065033630Mouse
1302070Tbbmd7_mtotal body bone mineral density 7 (mouse)Not determined171506165249061760Mouse
1302069Bbaa8_mB.burgdorferi-associated arthritis 8 (mouse)Not determined174305118543976235Mouse
10412214Sxbq3_mSGC/Knj cross B6 QTL 3 (mouse)Not determined171746220851462345Mouse
10412083Sm2_msusceptibility to Schistosoma mansoni infection 2 (mouse)Not determined171702994351030078Mouse
10412204Bbaa29_mB.burgdorferi-associated arthritis 29 (mouse)Not determined172605118560051352Mouse
12904951Smmq2_msoleus muscle mass QTL 2 (mouse)173678974370789743Mouse
4141067Hbnr2_mHeligmosomoides bakeri nematode resistance 2 (mouse)Not determined1188597145886119Mouse
12904946Tammq8_mtibialis anterior muscle mass QTL 8 (mouse)171245178746451787Mouse
10412198Sst5_msusceptibility to tuberculosis 5 (mouse)Not determined172507658355712970Mouse
4141319Hmtb8_mhemostasis and thrombosis rebleeding time 8 (mouse)Not determined4053444774534623Mouse
15039324Nmrs48_mNAFLD-associated magnetic resonance shift 48 (mouse)174093918774939187Mouse
10412196Bbaa28_mB.burgdorferi-associated arthritis 28 (mouse)Not determined172558491443976235Mouse
1301331Lbw1_mlupus NZB x NZW 1 (mouse)Not determined171841835752420983Mouse
1301840Ssial4_msusceptibility to sialadenitiss 4 (mouse)Not determined171817541252178214Mouse
1357789Kdnw3_mkidney weight 3 (mouse)Not determined17485475247885665Mouse
1301338Lmr1_mleishmaniasis resistance 1 (mouse)Not determined171008134086996400Mouse
1300703Uvbi2_mUVB induced immunosuppression 2 (mouse)Not determined172862240662622654Mouse
1301056Pas2_mpulmonary adenoma susceptibility 2 (mouse)Not determined171842214152424327Mouse
1301454Eae5_msusceptibility to experimental allergic encephalomyelitis 5 (mouse)Not determined172461275058612864Mouse
10755525Lymph2_mlymphocyte differential 2 (mouse)173880562672805626Mouse
14747010Mancz14_mmandible centroid size 14 (mouse)171199818445998184Mouse
1300592Pcyts5_mplasmacytoma susceptibility 5 (mouse)Not determined173871288772712970Mouse
1302005Loco2_mlocomotor activity 2 (mouse)Not determined172688497260885114Mouse
4141272Tfv1_mtotal food volume 1 (mouse)Not determined485475265637357Mouse
10755534Lymph4_mlymphocyte differential 4 (mouse)173880562672805626Mouse
1302140Wta4_mweight adult 4 (mouse)Not determined171681972150819843Mouse
1300706Alan1_malloantigen response 1 (mouse)Not determined17485475246469702Mouse
1558886Lgth9_mbody length 9 (mouse)Not determined171506165249061760Mouse
1558758Kcal2_mkilocalorie 2 (mouse)Not determined172640101252911704Mouse
1301474Hcbip2_mhexachlorobenzene induced porphyria 2 (mouse)Not determined173779305545622654Mouse
4142150Stheal11_msoft tissue heal 11 (mouse)Not determined171228621183361768Mouse
11081168Tir7_mtrypanosome infection response 7 (mouse)171412337248123496Mouse
1300589Myaa2_mmodifier of Yaa 2 (mouse)Not determined173013255564132666Mouse

Markers in Region
UniSTS:237554  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv37173,310,873 - 3,311,128UniSTSGRCm37
MGSCv371742,931,907 - 42,932,161UniSTSGRCm37
Celera173,851,508 - 3,851,763UniSTS
Celera1746,203,897 - 46,204,152UniSTS
RH126464  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38173,312,098 - 3,312,303UniSTSGRCm38
MGSCv37173,312,098 - 3,312,303UniSTSGRCm37
Cytogenetic Map17B3UniSTS
Cytogenetic Map17A1UniSTS
Whitehead/MRC_RH170.0UniSTS
D17Brg10  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381742,795,721 - 42,795,919UniSTSGRCm38
GRCm38173,311,648 - 3,311,840UniSTSGRCm38
MGSCv371742,932,670 - 42,932,868UniSTSGRCm37
MGSCv37173,311,648 - 3,311,840UniSTSGRCm37
Celera1746,204,661 - 46,204,862UniSTS
Celera173,852,745 - 3,852,944UniSTS
Cytogenetic Map17A1UniSTS
Cytogenetic Map17B3UniSTS
cM Map17 UniSTS
Cd2ap  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38173,312,946 - 3,313,883UniSTSGRCm38
GRCm38910,734,906 - 10,735,847UniSTSGRCm38
MGSCv37173,312,946 - 3,313,883UniSTSGRCm37
MGSCv37910,734,906 - 10,735,847UniSTSGRCm37
Celera173,854,054 - 3,855,005UniSTS
Celera98,111,019 - 8,111,960UniSTS
Cytogenetic Map17B3UniSTS
Cytogenetic Map9A1UniSTS
Cytogenetic Map17A1UniSTS
cM Map17 UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001410466 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001410467 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001410468 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_009847 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_177075 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011246263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC111082 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC117257 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF077003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF149092 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ459109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK040708 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK045218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK046750 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK047839 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK082763 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK131843 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205774 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB643447 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC019744 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC058409 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC138374 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC157901 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466559 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000024709   ⟹   ENSMUSP00000024709
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1743,103,842 - 43,187,280 (-)Ensembl
GRCm38.p6 Ensembl1742,792,951 - 42,876,389 (-)Ensembl
Ensembl Acc Id: ENSMUST00000233123
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1743,117,686 - 43,121,483 (-)Ensembl
GRCm38.p6 Ensembl1742,806,795 - 42,810,592 (-)Ensembl
Ensembl Acc Id: ENSMUST00000233195
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1743,127,155 - 43,187,556 (-)Ensembl
GRCm38.p6 Ensembl1742,816,264 - 42,876,665 (-)Ensembl
Ensembl Acc Id: ENSMUST00000233350
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1743,103,843 - 43,110,779 (-)Ensembl
GRCm38.p6 Ensembl1742,792,952 - 42,799,888 (-)Ensembl
Ensembl Acc Id: ENSMUST00000233476   ⟹   ENSMUSP00000156812
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1743,105,769 - 43,187,315 (-)Ensembl
GRCm38.p6 Ensembl1742,794,878 - 42,876,424 (-)Ensembl
Ensembl Acc Id: ENSMUST00000233626
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1743,136,312 - 43,141,921 (-)Ensembl
GRCm38.p6 Ensembl1742,825,421 - 42,831,030 (-)Ensembl
RefSeq Acc Id: NM_001410466   ⟹   NP_001397395
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391743,103,842 - 43,187,339 (-)NCBI
RefSeq Acc Id: NM_001410467   ⟹   NP_001397396
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391743,103,842 - 43,187,339 (-)NCBI
RefSeq Acc Id: NM_001410468   ⟹   NP_001397397
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391743,103,842 - 43,187,339 (-)NCBI
RefSeq Acc Id: NM_009847   ⟹   NP_033977
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391743,103,842 - 43,187,339 (-)NCBI
GRCm381742,792,951 - 42,876,424 (-)NCBI
MGSCv371742,929,900 - 43,013,373 (-)RGD
Celera1746,201,889 - 46,261,450 (-)RGD
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_177075
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391743,103,842 - 43,187,339 (-)NCBI
RefSeq Acc Id: XM_011246263   ⟹   XP_011244565
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391743,059,857 - 43,187,593 (-)NCBI
GRCm381742,748,887 - 42,876,704 (-)NCBI
Sequence:
RefSeq Acc Id: NP_033977   ⟸   NM_009847
- Peptide Label: isoform 1
- UniProtKB: Q8K4Z1 (UniProtKB/Swiss-Prot),   O88903 (UniProtKB/Swiss-Prot),   E9QL86 (UniProtKB/Swiss-Prot),   Q8VCI9 (UniProtKB/Swiss-Prot),   Q9JLQ0 (UniProtKB/Swiss-Prot),   B2RRE8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011244565   ⟸   XM_011246263
- Peptide Label: isoform X1
- UniProtKB: B2RRE8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000156812   ⟸   ENSMUST00000233476
Ensembl Acc Id: ENSMUSP00000024709   ⟸   ENSMUST00000024709
RefSeq Acc Id: NP_001397397   ⟸   NM_001410468
- Peptide Label: isoform 4
- UniProtKB: A0A3B2W812 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001397395   ⟸   NM_001410466
- Peptide Label: isoform 2
RefSeq Acc Id: NP_001397396   ⟸   NM_001410467
- Peptide Label: isoform 3
Protein Domains
SH3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9JLQ0-F1-model_v2 AlphaFold Q9JLQ0 1-637 view protein structure

Promoters
RGD ID:13676100
Promoter ID:EPDNEW_M22199
Type:initiation region
Name:Cd2ap_1
Description:Mus musculus CD2-associated protein , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381742,876,426 - 42,876,486EPDNEW
RGD ID:6827920
Promoter ID:MM_KWN:23523
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000024709
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361743,013,191 - 43,013,691 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1330281 AgrOrtholog
Ensembl Genes ENSMUSG00000023916
  ENSMUSG00000061665 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000024709 ENTREZGENE
  ENSMUST00000024709.9 UniProtKB/Swiss-Prot
  ENSMUST00000233476 ENTREZGENE
  ENSMUST00000233476.2 UniProtKB/TrEMBL
Gene3D-CATH SH3 Domains UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro CD2AP_SH3_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CD2AP_SH3_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CD2AP_SH_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Endophilin_SH3RF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:12488 UniProtKB/Swiss-Prot
MGD MGI:1330281 ENTREZGENE
NCBI Gene 12488 ENTREZGENE
PANTHER CD2-ASSOCIATED PROTEIN UniProtKB/Swiss-Prot
  LD44138P UniProtKB/TrEMBL
  PTHR14167:SF23 UniProtKB/TrEMBL
  SH3 DOMAIN-CONTAINING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam SH3_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_9 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cd2ap PhenoGen
PRINTS P67PHOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50044 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A3B2W812 ENTREZGENE, UniProtKB/TrEMBL
  B2RRE8 ENTREZGENE, UniProtKB/TrEMBL
  CD2AP_MOUSE UniProtKB/Swiss-Prot
  E9QL86 ENTREZGENE
  O88903 ENTREZGENE
  Q8K4Z1 ENTREZGENE
  Q8VCI9 ENTREZGENE
  Q9JLQ0 ENTREZGENE
UniProt Secondary E9QL86 UniProtKB/Swiss-Prot
  O88903 UniProtKB/Swiss-Prot
  Q8K4Z1 UniProtKB/Swiss-Prot
  Q8VCI9 UniProtKB/Swiss-Prot