Kras (Kirsten rat sarcoma viral oncogene homolog) - Rat Genome Database

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Gene: Kras (Kirsten rat sarcoma viral oncogene homolog) Mus musculus
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Symbol: Kras
Name: Kirsten rat sarcoma viral oncogene homolog
RGD ID: 1550157
MGI Page MGI
Description: Enables GTPase activity and membrane-membrane adaptor activity. Acts upstream of or within several processes, including Ras protein signal transduction; forebrain astrocyte development; and modulation of chemical synaptic transmission. Located in membrane. Is expressed in several structures, including alimentary system; brain; eye; genitourinary system; and limb. Used to study several diseases, including Noonan syndrome 3; arteriovenous malformations of the brain; gastrointestinal system cancer (multiple); pancreatic carcinoma (multiple); and reproductive organ cancer (multiple). Human ortholog(s) of this gene implicated in several diseases, including Noonan syndrome (multiple); cardiofaciocutaneous syndrome (multiple); gastrointestinal system cancer (multiple); hematologic cancer (multiple); and lung cancer (multiple). Orthologous to human KRAS (KRAS proto-oncogene, GTPase).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI929937; c-K-ras; c-Ki-ras; GTPase KRas; K-; K-ras; K-Ras 2; Ki; Ki-ras; Kirsten rat sarcoma oncogene 2, expressed; Kr; Kra; Kras-2; Kras2; MGC7141; p21 protein; p21B; ras; v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396145,162,425 - 145,197,631 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6145,162,425 - 145,195,965 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm386145,216,699 - 145,250,420 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6145,216,699 - 145,250,239 (-)Ensemblmm10GRCm38
MGSCv376145,165,219 - 145,198,751 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv366145,173,866 - 145,207,390 (-)NCBIMGSCv36mm8
Celera6148,290,985 - 148,324,546 (-)NCBICelera
Cytogenetic Map6G3NCBI
cM Map677.37NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View
Acute Experimental Pancreatitis  (ISO)
acute lymphoblastic leukemia  (ISO)
acute myeloid leukemia  (ISO)
adenocarcinoma  (ISO)
adenoma  (ISO)
anaplastic astrocytoma  (ISO)
anemia  (ISO)
angiosarcoma  (ISO)
Animal Disease Models  (ISO)
arteriovenous malformations of the brain  (IAGP,ISO)
autoimmune lymphoproliferative syndrome type 4  (ISO)
breast adenocarcinoma  (ISO)
breast cancer  (ISO)
Breast Cancer, Familial  (ISO)
Breast Neoplasms  (ISO)
bronchiolo-alveolar adenocarcinoma  (IMP)
Capillary Malformation-Arteriovenous Malformation 1  (ISO)
Carcinogenesis  (ISO)
carcinoma  (ISO)
cardiofaciocutaneous syndrome  (ISO)
cardiofaciocutaneous syndrome 1  (ISO)
cardiofaciocutaneous syndrome 2  (ISO)
cardiomyopathy  (IMP)
Cecal Neoplasms  (ISO)
cholangiocarcinoma  (ISO)
chronic myelogenous leukemia, BCR-ABL1 positive  (ISO)
Colonic Neoplasms  (ISO)
colorectal cancer  (ISO)
Colorectal Neoplasms  (IDA,ISO)
Costello syndrome  (ISO)
dilated cardiomyopathy  (IDA)
disease of cellular proliferation  (ISO)
Disease Progression  (ISO)
Encephalocraniocutaneous Lipomatosis  (ISO)
endometrial adenocarcinoma  (ISO)
endometrial carcinoma  (ISO)
endometrial hyperplasia  (ISO)
Endometrial Hyperplasia without Atypia  (ISO)
Endometrial Intraepithelial Neoplasia  (ISO)
Endometrial Neoplasms  (ISO)
Endometrioid Carcinomas  (ISO)
endometriosis  (IAGP,ISO)
epidermal nevus  (ISO)
Experimental Liver Neoplasms  (ISO)
Experimental Neoplasms  (ISO)
Experimental Sarcoma  (ISO)
Familial Pancreatic Carcinoma  (ISO)
fibrillary astrocytoma  (ISO)
follicular thyroid carcinoma  (ISO)
gallbladder cancer  (ISO)
Gallbladder Neoplasms  (ISO)
gastrointestinal stromal tumor  (ISO)
genetic disease  (ISO)
glioblastoma  (IMP,ISO)
hepatocellular adenoma  (ISO)
hepatocellular carcinoma  (ISO)
hereditary breast ovarian cancer syndrome  (ISO)
hereditary diffuse gastric cancer  (ISO)
high grade glioma  (IMP,ISO)
Hodgkin's lymphoma  (ISO)
Hydrops Fetalis  (ISO)
hypertension  (IDA)
intellectual disability  (ISO)
intrahepatic cholangiocarcinoma  (IAGP,ISO)
juvenile myelomonocytic leukemia  (IAGP,ISO)
juvenile rheumatoid arthritis  (ISO)
Kidney Neoplasms  (ISO)
Klatskin's tumor  (ISO)
Leukocytosis  (ISO)
linear nevus sebaceous syndrome  (ISO)
Liver Neoplasms  (ISO)
lung adenocarcinoma  (ISO)
lung cancer  (IAGP,ISO)
lung carcinoma  (ISO)
Lung Neoplasms  (IMP,ISO)
lung non-small cell carcinoma  (ISO)
Lung Reperfusion Injury  (IEP)
lung sarcomatoid carcinoma  (ISO)
lung squamous cell carcinoma  (ISO)
lymphoma  (ISO)
Lynch syndrome  (ISO)
malignant astrocytoma  (IGI,ISO)
Mouth Neoplasms  (ISO)
Multiple Abnormalities  (ISO)
multiple myeloma  (ISO)
muscular atrophy  (ISO)
myelodysplastic syndrome  (ISO)
myeloid neoplasm  (IMP)
myeloid sarcoma  (ISO)
Neoplasm Metastasis  (IEP,ISO)
Neoplastic Cell Transformation  (ISO)
neuroblastoma  (ISO)
Noonan syndrome  (IMP,ISO)
Noonan syndrome 1  (ISO)
Noonan syndrome 3  (IAGP,ISO)
oculoectodermal syndrome  (ISO)
Ovarian Neoplasms  (ISO)
ovary serous adenocarcinoma  (ISO)
pancreatic cancer  (ISO)
pancreatic carcinoma  (IAGP,ISO)
pancreatic ductal carcinoma  (ISO)
pancreatic mucinous cystadenoma  (ISO)
Parasitic Liver Diseases  (ISO)
Penile Neoplasms  (ISO)
pilocytic astrocytoma  (ISO)
prostate cancer  (IAGP)
Prostate Cancer, Hereditary, 1  (ISO)
prostate carcinoma in situ  (IAGP)
Prostatic Neoplasms  (IAGP,ISO)
RASopathy  (ISO)
Recurrence  (ISO)
renal cell carcinoma  (ISO)
renal fibrosis  (ISO)
Sebaceous Nevus Syndrome and Hemimegalencephaly  (ISO)
seminoma  (ISO)
Splenomegaly  (ISO)
squamous cell carcinoma  (ISO)
stomach cancer  (ISO)
stomach carcinoma  (ISO)
Stomach Neoplasms  (ISO)
T-cell acute lymphoblastic leukemia  (IMP)
teratoma  (ISO)
Thyroid Carcinoma, Nonmedullary 1  (ISO)
Thyroid Neoplasms  (ISO)
transitional cell carcinoma  (ISO)
Triple Negative Breast Neoplasms  (ISO)
urinary bladder cancer  (ISO)
Urinary Bladder Neoplasm  (ISO)
Uterine Cervical Neoplasms  (ISO)
Uterine Neoplasms  (ISO)
Vascular Malformations  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-colchicine  (EXP)
(S)-naringenin  (ISO)
(trichloromethyl)benzene  (EXP)
1,1-dichloroethene  (EXP)
1,2-dimethylhydrazine  (EXP)
1-nitropyrene  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
2,2-Bis(bromomethyl)propane-1,3-diol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
2,6-di-tert-butyl-4-methylphenol  (EXP)
2,6-dimethoxyphenol  (ISO)
2-trans,6-trans-farnesyl diphosphate  (ISO)
3-methyl-3H-imidazo[4,5-f]quinolin-2-amine  (ISO)
3-methylcholanthrene  (EXP)
4,4'-sulfonyldiphenol  (EXP)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (EXP,ISO)
4-nitrophenol  (EXP)
4-vinylcyclohexene dioxide  (EXP)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
5-Methylchrysene  (EXP)
acrolein  (ISO)
actinomycin D  (ISO)
afimoxifene  (ISO)
ammonium chloride  (ISO)
amphetamine  (ISO)
antirheumatic drug  (ISO)
Antrocin  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (EXP)
ARS-1620  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
asbestos  (ISO)
Azoxymethane  (EXP,ISO)
Benz[j]aceanthrylene  (EXP)
benzene  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (EXP)
bisphenol A  (EXP,ISO)
bleomycin A2  (EXP)
buta-1,3-diene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
cannabidiol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP)
ceruletide  (EXP)
CGP 52608  (ISO)
chloroethene  (EXP,ISO)
chloroprene  (EXP)
chlorpyrifos  (ISO)
chymostatin  (ISO)
cisplatin  (ISO)
clofibrate  (EXP)
cobalt atom  (EXP,ISO)
cobimetinib  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
coumestrol  (ISO)
crizotinib  (ISO)
cumene  (EXP)
Cuprizon  (ISO)
curcumin  (EXP,ISO)
cycloheximide  (ISO)
Cyclopenta[cd]pyrene  (EXP)
dabrafenib  (ISO)
dextran sulfate  (EXP)
dibenzo[a,l]pyrene  (EXP)
Dibutyl phosphate  (ISO)
dichlorine  (ISO)
diclofenac  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
emamectin benzoate  (ISO)
erianin  (EXP)
erlotinib hydrochloride  (ISO)
ethanol  (EXP)
farnesyl diphosphate  (ISO)
flutamide  (ISO)
folic acid  (EXP)
furfural  (ISO)
GDP  (ISO)
gefitinib  (ISO)
genistein  (ISO)
gentamycin  (ISO)
geraniol  (ISO)
GTP  (ISO)
guanosine  (ISO)
haloperidol  (ISO)
hydrogen peroxide  (EXP)
hydroquinone  (ISO)
hydroxyurea  (EXP)
ionomycin  (ISO)
irbesartan  (EXP,ISO)
isoprenaline  (EXP)
isoprene  (EXP)
isotretinoin  (ISO)
ivermectin  (ISO)
kainic acid  (ISO)
L-744832  (ISO)
lapatinib  (ISO)
lead diacetate  (EXP,ISO)
lead(0)  (EXP)
lipopolysaccharide  (EXP,ISO)
losartan  (ISO)
lovastatin  (EXP,ISO)
luzindole  (EXP)
manumycin A  (ISO)
MeIQx  (ISO)
mercury dibromide  (ISO)
metformin  (ISO)
methohexital  (ISO)
methotrexate  (ISO)
metyrapone  (ISO)
monosodium L-glutamate  (ISO)
Morindone  (ISO)
N,N-bis(2-hydroxypropyl)nitrosamine  (ISO)
N-acetyl-L-cysteine  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-ethyl-N-nitrosourea  (EXP)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
N-methyl-N-nitrosourea  (EXP,ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (EXP)
nicotinic acid  (EXP)
nitrates  (EXP)
ochratoxin A  (ISO)
oncrasin-1  (ISO)
oxirane  (EXP)
oxybenzone  (ISO)
ozone  (ISO)
p-chloromercuribenzoic acid  (ISO)
paclitaxel  (ISO)
paracetamol  (EXP)
PD 0325901  (EXP,ISO)
pemetrexed  (ISO)
pentobarbital  (ISO)
phlorizin  (EXP)
phorbol 13-acetate 12-myristate  (EXP,ISO)
picrotoxin  (ISO)
piperonyl butoxide  (ISO)
pirinixic acid  (ISO)
quercetin  (ISO)
Rebamipide  (ISO)
resveratrol  (EXP,ISO)
riddelliine  (EXP)
sarin  (ISO)
SB 431542  (ISO)
secobarbital  (ISO)
selumetinib  (ISO)
sevoflurane  (ISO)
simvastatin  (ISO)
sodium arsenite  (EXP,ISO)
sodium chloride  (ISO)
Soman  (ISO)
sotorasib  (ISO)
styrene  (EXP)
sulfur dioxide  (ISO)
sulindac  (ISO)
sunitinib  (ISO)
tacrolimus hydrate  (EXP)
Tanshinone I  (EXP,ISO)
Temsirolimus  (ISO)
testosterone enanthate  (ISO)
tetrachloromethane  (EXP,ISO)
Tetranitromethane  (EXP)
thiamylal  (ISO)
thimerosal  (ISO)
thioacetamide  (ISO)
tiazofurine  (ISO)
tipifarnib  (ISO)
titanium dioxide  (EXP)
toluene  (ISO)
trimetrexate  (ISO)
Triptolide  (ISO)
triptonide  (EXP)
urethane  (EXP,ISO)
ursodeoxycholic acid  (ISO)
valproic acid  (ISO)
vemurafenib  (ISO)
vinyl carbamate  (EXP)
zearalenone  (EXP)
zidovudine  (EXP)
zinc protoporphyrin  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
actin cytoskeleton organization  (IGI)
cardiac muscle cell proliferation  (IEA,ISO)
cell population proliferation  (IGI)
cytokine-mediated signaling pathway  (IEA,ISO)
epithelial tube branching involved in lung morphogenesis  (IDA,IGI)
female pregnancy  (IEA,ISO)
forebrain astrocyte development  (IMP)
gene expression  (IMP)
glial cell proliferation  (IGI)
homeostasis of number of cells within a tissue  (IGI)
insulin-like growth factor receptor signaling pathway  (ISO)
liver development  (IEA,ISO)
myoblast proliferation  (IEA,ISO)
negative regulation of epithelial cell differentiation  (IDA)
negative regulation of neuron apoptotic process  (IGI)
neuron apoptotic process  (IGI)
positive regulation of cellular senescence  (IEA,ISO)
positive regulation of gene expression  (IEA,IMP,ISO)
positive regulation of glial cell proliferation  (IGI)
positive regulation of MAP kinase activity  (ISO)
positive regulation of NF-kappaB transcription factor activity  (ISO)
positive regulation of nitric-oxide synthase activity  (ISO)
positive regulation of Rac protein signal transduction  (IGI)
Rac protein signal transduction  (IGI)
Ras protein signal transduction  (IBA,IGI,IMP,TAS)
regulation of long-term neuronal synaptic plasticity  (IGI)
regulation of synaptic transmission, GABAergic  (IGI)
response to glucocorticoid  (IEA,ISO)
response to gravity  (IEA,ISO)
response to isolation stress  (IEA,ISO)
response to mineralocorticoid  (IEA,ISO)
signal transduction  (IEA)
skeletal muscle cell differentiation  (IGI)
striated muscle cell differentiation  (IGI)
type I pneumocyte differentiation  (IDA)
visual learning  (IGI)

Cellular Component
cytoplasm  (IEA,ISO,ISS)
cytoplasmic side of plasma membrane  (IEA,ISO,ISS)
endomembrane system  (IEA)
membrane  (IDA,IEA,IGI)
plasma membrane  (IBA,IEA,ISO,TAS)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal astrocyte morphology  (IAGP)
abnormal atrioventricular valve morphology  (IAGP)
abnormal blood cell morphology/development  (IAGP)
abnormal bone marrow cell physiology  (IAGP)
abnormal brain development  (IAGP)
abnormal brain vasculature morphology  (IAGP)
abnormal branching involved in lung morphogenesis  (IAGP)
abnormal bronchiole morphology  (IAGP)
abnormal bronchoalveolar duct junction morphology  (IAGP)
abnormal bronchus epithelium morphology  (IAGP)
abnormal bronchus morphology  (IAGP)
abnormal cardiovascular system physiology  (IAGP)
abnormal cell cycle  (IAGP)
abnormal cell morphology  (IAGP)
abnormal cell proliferation  (IAGP)
abnormal centrosome morphology  (IAGP)
abnormal CNS glial cell morphology  (IAGP)
abnormal colon goblet cell morphology  (IAGP)
abnormal colon morphology  (IAGP)
abnormal common lymphocyte progenitor cell morphology  (IAGP)
abnormal common myeloid progenitor cell morphology  (IAGP)
abnormal cone electrophysiology  (IAGP)
abnormal cranium morphology  (IAGP)
abnormal cystic duct morphology  (IAGP)
abnormal definitive hematopoiesis  (IAGP)
abnormal DNA repair  (IAGP)
abnormal duodenum morphology  (IAGP)
abnormal ear position  (IAGP)
abnormal embryonic erythrocyte morphology  (IAGP)
abnormal embryonic erythropoiesis  (IAGP)
abnormal embryonic hematopoiesis  (IAGP)
abnormal embryonic neuroepithelium morphology  (IAGP)
abnormal enterocyte proliferation  (IAGP)
abnormal erythrocyte morphology  (IAGP)
abnormal erythropoiesis  (IAGP)
abnormal exocrine pancreas morphology  (IAGP)
abnormal extrahepatic bile duct morphology  (IAGP)
abnormal eye development  (IAGP)
abnormal facial morphology  (IAGP)
abnormal fibroblast proliferation  (IAGP)
abnormal gallbladder morphology  (IAGP)
abnormal heart morphology  (IAGP)
abnormal hematopoietic system morphology/development  (IAGP)
abnormal hepatic portal vein morphology  (IAGP)
abnormal hepatic portal vein thrombosis  (IAGP)
abnormal hepatobiliary system morphology  (IAGP)
abnormal hepatocyte morphology  (IAGP)
abnormal hippocampus morphology  (IAGP)
abnormal intestinal epithelium morphology  (IAGP)
abnormal intestinal goblet cell morphology  (IAGP)
abnormal intestine morphology  (IAGP)
abnormal kidney morphology  (IAGP)
abnormal lacrimal gland development  (IAGP)
abnormal large intestine crypts of Lieberkuhn morphology  (IAGP)
abnormal liver morphology  (IAGP)
abnormal lung adenoma incidence  (IAGP)
abnormal lung development  (IAGP)
abnormal lung epithelium morphology  (IAGP)
abnormal lung morphology  (IAGP)
abnormal lymphatic vessel morphology  (IAGP)
abnormal melanocyte morphology  (IAGP)
abnormal metabolism  (IAGP)
abnormal metastatic potential  (IAGP)
abnormal mismatch repair  (IAGP)
abnormal myeloid leukocyte morphology  (IAGP)
abnormal myelopoiesis  (IAGP)
abnormal myocardial fiber physiology  (IAGP)
abnormal ovary morphology  (IAGP)
abnormal pancreas development  (IAGP)
abnormal pancreas morphology  (IAGP)
abnormal pancreatic acinar cell morphology  (IAGP)
abnormal pancreatic duct morphology  (IAGP)
abnormal peritoneum morphology  (IAGP)
abnormal placenta labyrinth morphology  (IAGP)
abnormal placental labyrinth vasculature morphology  (IAGP)
abnormal prostate gland morphology  (IAGP)
abnormal prostate gland physiology  (IAGP)
abnormal pulmonary alveolus morphology  (IAGP)
abnormal rod electrophysiology  (IAGP)
abnormal skin sebaceous gland morphology  (IAGP)
abnormal spleen morphology  (IAGP)
abnormal survival  (IAGP)
abnormal systemic arterial blood pressure  (IAGP)
abnormal translation  (IAGP)
abnormal tumor incidence  (IAGP)
abnormal tumor morphology  (IAGP)
absent lacrimal glands  (IAGP)
absent Paneth cells  (IAGP)
absent visceral yolk sac blood islands  (IAGP)
absent vitelline blood vessels  (IAGP)
anemia  (IAGP)
anisopoikilocytosis  (IAGP)
arteriovenous malformation  (IAGP)
ascites  (IAGP)
bile duct hyperplasia  (IAGP)
bronchial epithelial hyperplasia  (IAGP)
bronchiolar epithelial hyperplasia  (IAGP)
cachexia  (IAGP)
cardiac fibrosis  (IAGP)
cellular necrosis  (IAGP)
cholestasis  (IAGP)
chromosomal instability  (IAGP)
chromosome breakage  (IAGP)
chylous ascites  (IAGP)
conotruncal ridge hyperplasia  (IAGP)
decreased a-wave amplitude  (IAGP)
decreased B cell number  (IAGP)
decreased b-wave amplitude  (IAGP)
decreased body length  (IAGP)
decreased body size  (IAGP)
decreased CD8-positive, alpha-beta T cell number  (IAGP)
decreased cell proliferation  (IAGP)
decreased circulating estradiol level  (IAGP)
decreased circulating progesterone level  (IAGP)
decreased circulating thyroid-stimulating hormone level  (IAGP)
decreased classified tumor incidence  (IAGP)
decreased cranium length  (IAGP)
decreased double-negative T cell number  (IAGP)
decreased double-positive T cell number  (IAGP)
decreased embryo size  (IAGP)
decreased fetal cardiomyocyte proliferation  (IAGP)
decreased fibroblast proliferation  (IAGP)
decreased gland tumor incidence  (IAGP)
decreased glutamic acid level  (IAGP)
decreased heart left ventricle muscle contractility  (IAGP)
decreased hematocrit  (IAGP)
decreased hematopoietic stem cell number  (IAGP)
decreased hemoglobin content  (IAGP)
decreased incidence of induced tumors  (IAGP)
decreased incidence of tumors by chemical induction  (IAGP)
decreased interferon-gamma secretion  (IAGP)
decreased lung tumor incidence  (IAGP)
decreased lymphocyte cell number  (IAGP)
decreased lymphoma incidence  (IAGP)
decreased mean corpuscular hemoglobin  (IAGP)
decreased metastatic potential  (IAGP)
decreased ovarian tumor incidence  (IAGP)
decreased skin tumor incidence  (IAGP)
decreased survivor rate  (IAGP)
decreased susceptibility to induced pancreatitis  (IAGP)
decreased T cell number  (IAGP)
decreased tumor growth/size  (IAGP)
decreased tumor incidence  (IAGP)
decreased tumor latency  (IAGP)
decreased tumor-free survival time  (IAGP)
dilated bile duct  (IAGP)
dilated cardiomyopathy  (IAGP)
dilated gallbladder  (IAGP)
dilated heart  (IAGP)
dilated pancreatic duct  (IAGP)
dilated respiratory conducting tube  (IAGP)
disorganized pancreatic islets  (IAGP)
distended abdomen  (IAGP)
distended pericardium  (IAGP)
double outlet right ventricle  (IAGP)
early cellular replicative senescence  (IAGP)
edema  (IAGP)
embryonic growth arrest  (IAGP)
embryonic growth retardation  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
embryonic lethality during organogenesis, incomplete penetrance  (IAGP)
embryonic lethality, complete penetrance  (IAGP)
embryonic lethality, incomplete penetrance  (IAGP)
enlarged heart  (IAGP)
enlarged liver  (IAGP)
enlarged lung  (IAGP)
enlarged pancreas  (IAGP)
enlarged pancreatic islets  (IAGP)
enlarged sebaceous gland  (IAGP)
enlarged spleen  (IAGP)
enlarged thyroid gland  (IAGP)
epidermal hyperplasia  (IAGP)
excessive folding of visceral yolk sac  (IAGP)
exocrine pancreas atrophy  (IAGP)
exocrine pancreatic insufficiency  (IAGP)
extramedullary hematopoiesis  (IAGP)
fetal growth retardation  (IAGP)
flattened snout  (IAGP)
Harderian gland hyperplasia  (IAGP)
heart hyperplasia  (IAGP)
hemoperitoneum  (IAGP)
hemorrhage  (IAGP)
hemorrhagic ascites  (IAGP)
hepatic necrosis  (IAGP)
hepatosplenomegaly  (IAGP)
hunched posture  (IAGP)
hydrops fetalis  (IAGP)
hyperpigmentation  (IAGP)
hypertension  (IAGP)
impaired branching involved in bronchus morphogenesis  (IAGP)
impaired branching involved in terminal bronchiole morphogenesis  (IAGP)
impaired granulosa cell differentiation  (IAGP)
increased adenocarcinoma incidence  (IAGP)
increased adenoma incidence  (IAGP)
increased apoptosis  (IAGP)
increased B cell number  (IAGP)
increased basophil cell number  (IAGP)
increased body weight  (IAGP)
increased carcinoma incidence  (IAGP)
increased cardiac muscle contractility  (IAGP)
increased cardiac output  (IAGP)
increased cell proliferation  (IAGP)
increased cellular sensitivity to oxidative stress  (IAGP)
increased cholangiocarcinoma incidence  (IAGP)
increased circulating erythropoietin level  (IAGP)
increased circulating follicle stimulating hormone level  (IAGP)
increased circulating luteinizing hormone level  (IAGP)
increased classified tumor incidence  (IAGP)
increased colon adenoma incidence  (IAGP)
increased cranium height  (IAGP)
increased cranium width  (IAGP)
increased cutaneous melanoma incidence  (IAGP)
increased dendritic cell number  (IAGP)
increased embryonic neuroepithelium apoptosis  (IAGP)
increased embryonic tissue cell apoptosis  (IAGP)
increased endometrial carcinoma incidence  (IAGP)
increased eosinophil cell number  (IAGP)
increased esophageal papilloma incidence  (IAGP)
increased facial tumor incidence  (IAGP)
increased fibroblast proliferation  (IAGP)
increased fibrosarcoma incidence  (IAGP)
increased gastrointestinal tumor incidence  (IAGP)
increased granulocyte monocyte progenitor cell number  (IAGP)
increased granulocyte number  (IAGP)
increased granulosa cell tumor incidence  (IAGP)
increased hair follicle cell proliferation  (IAGP)
increased hamartoma incidence  (IAGP)
increased hemangiosarcoma incidence  (IAGP)
increased hematopoietic stem cell number  (IAGP)
increased hemolymphoid system tumor incidence  (IAGP)
increased hepatocellular carcinoma incidence  (IAGP)
increased hepatocyte apoptosis  (IAGP)
increased IgG level  (IAGP)
increased IgM level  (IAGP)
increased incidence of tumors by chemical induction  (IAGP)
increased inflammatory response  (IAGP)
increased intestinal adenocarcinoma incidence  (IAGP)
increased leukemia incidence  (IAGP)
increased leukocyte cell number  (IAGP)
increased lip tumor incidence  (IAGP)
increased liver tumor incidence  (IAGP)
increased lung adenocarcinoma incidence  (IAGP)
increased lung adenoma incidence  (IAGP)
increased lung carcinoma incidence  (IAGP)
increased lung large cell carcinoma incidence  (IAGP)
increased lung non-small cell carcinoma incidence  (IAGP)
increased lung squamous cell carcinoma incidence  (IAGP)
increased lung tumor incidence  (IAGP)
increased lung weight  (IAGP)
increased lymphoblastic lymphoma incidence  (IAGP)
increased lymphoma incidence  (IAGP)
increased macrophage cell number  (IAGP)
increased malignant tumor incidence  (IAGP)
increased melanoma incidence  (IAGP)
increased mesothelioma incidence  (IAGP)
increased metastatic potential  (IAGP)
increased monocyte cell number  (IAGP)
increased mouth tumor incidence  (IAGP)
increased myeloid cell number  (IAGP)
increased myeloid cell number in bone marrow  (IAGP)
increased myocardial fiber number  (IAGP)
increased myocardial fiber size  (IAGP)
increased neurofibroma incidence  (IAGP)
increased neurofibrosarcoma incidence  (IAGP)
increased neuron apoptosis  (IAGP)
increased neutrophil cell number  (IAGP)
increased oral papilloma incidence  (IAGP)
increased organ/body region tumor incidence  (IAGP)
increased osteosarcoma incidence  (IAGP)
increased ovary tumor incidence  (IAGP)
increased pancreas adenoma incidence  (IAGP)
increased pancreas apoptosis  (IAGP)
increased pancreas tumor incidence  (IAGP)
increased pancreas weight  (IAGP)
increased pancreatic acinar cell carcinoma incidence  (IAGP)
increased pancreatic ductal adenocarcinoma incidence  (IAGP)
increased pancreatic intraepithelial neoplasia incidence  (IAGP)
increased papilloma incidence  (IAGP)
increased pituitary adenoma incidence  (IAGP)
increased prostate gland adenocarcinoma incidence  (IAGP)
increased prostate gland tumor incidence  (IAGP)
increased prostate intraepithelial neoplasia incidence  (IAGP)
increased regulatory T cell number  (IAGP)
increased sarcoma incidence  (IAGP)
increased skin papilloma incidence  (IAGP)
increased skin squamous cell carcinoma incidence  (IAGP)
increased skin tumor incidence  (IAGP)
increased spindle cell carcinoma incidence  (IAGP)
increased spleen red pulp amount  (IAGP)
increased splenocyte proliferation  (IAGP)
increased squamous cell carcinoma incidence  (IAGP)
increased stomach tumor incidence  (IAGP)
increased susceptibility to induced pancreatitis  (IAGP)
increased systemic arterial diastolic blood pressure  (IAGP)
increased systemic arterial systolic blood pressure  (IAGP)
increased T cell derived lymphoma incidence  (IAGP)
increased T cell number  (IAGP)
increased teratocarcinoma incidence  (IAGP)
increased testis tumor incidence  (IAGP)
increased thyroid carcinoma incidence  (IAGP)
increased thyroxine level  (IAGP)
increased trichoepithelioma incidence  (IAGP)
increased tumor growth/size  (IAGP)
increased tumor incidence  (IAGP)
increased tumor latency  (IAGP)
increased tumor-free survival time  (IAGP)
increased type II pneumocyte number  (IAGP)
increased urinary bladder carcinoma incidence  (IAGP)
intestinal obstruction  (IAGP)
intracranial hemorrhage  (IAGP)
jaundice  (IAGP)
lethality throughout fetal growth and development, complete penetrance  (IAGP)
lethality, complete penetrance  (IAGP)
liver hypoplasia  (IAGP)
lung epithelium hyperplasia  (IAGP)
lung inflammation  (IAGP)
lymphatic vessel hypoplasia  (IAGP)
lymphedema  (IAGP)
lymphoid hyperplasia  (IAGP)
myeloid hyperplasia  (IAGP)
no abnormal phenotype detected  (IAGP)
ocular hypertelorism  (IAGP)
oxidative stress  (IAGP)
pale liver  (IAGP)
pale yolk sac  (IAGP)
pallor  (IAGP)
pancreas cyst  (IAGP)
pancreas hyperplasia  (IAGP)
pancreas inflammation  (IAGP)
pancreatic acinar-to-ductal metaplasia  (IAGP)
paralysis  (IAGP)
pericardial edema  (IAGP)
perinatal lethality, complete penetrance  (IAGP)
perinatal lethality, incomplete penetrance  (IAGP)
polychromatophilia  (IAGP)
postnatal growth retardation  (IAGP)
postnatal lethality  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
premature death  (IAGP)
prenatal lethality, complete penetrance  (IAGP)
prenatal lethality, incomplete penetrance  (IAGP)
prostate gland hyperplasia  (IAGP)
respiratory distress  (IAGP)
respiratory failure  (IAGP)
reticulocytosis  (IAGP)
ruffled hair  (IAGP)
sebaceous gland hyperplasia  (IAGP)
seminiferous tubule degeneration  (IAGP)
short tail  (IAGP)
skin lesions  (IAGP)
slow postnatal weight gain  (IAGP)
small heart  (IAGP)
small liver  (IAGP)
small pancreas  (IAGP)
spleen vascular congestion  (IAGP)
squamous metaplasia of bulbourethral gland  (IAGP)
squamous metaplasia of urethral gland  (IAGP)
stomach mucosa hyperplasia  (IAGP)
submandibular gland hyperplasia  (IAGP)
tachypnea  (IAGP)
thick aortic valve  (IAGP)
thick epidermis  (IAGP)
thick pulmonary interalveolar septum  (IAGP)
thin myocardium  (IAGP)
thin ventricular wall  (IAGP)
thrombocytopenia  (IAGP)
thymus atrophy  (IAGP)
triangular face  (IAGP)
uterus adenomyosis  (IAGP)
ventricular septal defect  (IAGP)
weight loss  (IAGP)
References

References - curated
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Additional References at PubMed
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PMID:9371744   PMID:9466889   PMID:9514948   PMID:9615230   PMID:9657861   PMID:9659579   PMID:9659582   PMID:9696043   PMID:9744549   PMID:9952298   PMID:10085069   PMID:10349636  
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PMID:37803016   PMID:37814340   PMID:37819952   PMID:37823551   PMID:37828026   PMID:37842094   PMID:37844756   PMID:37870961   PMID:37875245   PMID:37887282   PMID:37889752   PMID:37910602  
PMID:37913768   PMID:37914932   PMID:37922313   PMID:37931099   PMID:37931247   PMID:37931288   PMID:37934116   PMID:37995179   PMID:37998349   PMID:38056453   PMID:38093367   PMID:38110836  
PMID:38143011   PMID:38168062   PMID:38216551   PMID:38229581   PMID:38272100   PMID:38272889   PMID:38280479   PMID:38290660   PMID:38296052   PMID:38318686   PMID:38355776   PMID:38360999  
PMID:38402201   PMID:38427741   PMID:38460517   PMID:38462034   PMID:38467382   PMID:38469630   PMID:38473403   PMID:38478609   PMID:38547169   PMID:38574733   PMID:38605037   PMID:38636522  
PMID:38654064   PMID:38658753   PMID:38686559   PMID:38687749   PMID:38689013   PMID:38731942   PMID:38733583   PMID:38733589   PMID:38749447   PMID:38755258   PMID:38772364   PMID:38781455  
PMID:38796854   PMID:38805014   PMID:38816352   PMID:38816530   PMID:38834136   PMID:38842383   PMID:38843355   PMID:38849523   PMID:38872370   PMID:38875320   PMID:38887373   PMID:38901203  
PMID:38902237   PMID:38902362   PMID:38902475   PMID:38910965   PMID:38921956   PMID:38922866   PMID:38924548   PMID:38935717   PMID:38997257   PMID:39005053   PMID:39037766   PMID:39039076  
PMID:39048054   PMID:39048609   PMID:39048817   PMID:39079386   PMID:39112706   PMID:39128004   PMID:39137067   PMID:39178842   PMID:39178856   PMID:39213022   PMID:39232498   PMID:39236155  
PMID:39271958   PMID:39313617   PMID:39340215   PMID:39342278   PMID:39358651   PMID:39390257   PMID:39422661   PMID:39473974   PMID:39475511   PMID:39478206   PMID:39479750   PMID:39485842  
PMID:39515330   PMID:39537753   PMID:39576014   PMID:39577420   PMID:39587064   PMID:39627248   PMID:39652422   PMID:39690148   PMID:39721583   PMID:39778708   PMID:39811640   PMID:39819877  
PMID:39866228   PMID:39905264   PMID:39907430   PMID:39907729   PMID:39910147   PMID:39914384   PMID:39918337   PMID:39919745   PMID:39930268   PMID:39938515   PMID:39941740   PMID:39949931  
PMID:39952242   PMID:39956331   PMID:39970873   PMID:39972137   PMID:39972142   PMID:39996058   PMID:40021683   PMID:40044861   PMID:40047406   PMID:40072317   PMID:40073121   PMID:40073432  
PMID:40104059   PMID:40133474   PMID:40133477   PMID:40170241   PMID:40179020   PMID:40188436   PMID:40216153   PMID:40276763   PMID:40334547   PMID:40360735   PMID:40379682   PMID:40419509  
PMID:40442064   PMID:40447760   PMID:40454484   PMID:40521210  


Genomics

Comparative Map Data
Kras
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396145,162,425 - 145,197,631 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6145,162,425 - 145,195,965 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm386145,216,699 - 145,250,420 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6145,216,699 - 145,250,239 (-)Ensemblmm10GRCm38
MGSCv376145,165,219 - 145,198,751 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv366145,173,866 - 145,207,390 (-)NCBIMGSCv36mm8
Celera6148,290,985 - 148,324,546 (-)NCBICelera
Cytogenetic Map6G3NCBI
cM Map677.37NCBI
KRAS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381225,205,246 - 25,250,929 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1225,205,246 - 25,250,936 (-)Ensemblhg38GRCh38
GRCh371225,358,180 - 25,403,863 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361225,249,447 - 25,295,121 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341225,249,446 - 25,295,121NCBI
Celera1230,505,144 - 30,550,804 (-)NCBICelera
Cytogenetic Map12p12.1NCBI
HuRef1225,128,895 - 25,174,493 (-)NCBIHuRef
CHM1_11225,323,336 - 25,368,979 (-)NCBICHM1_1
T2T-CHM13v2.01225,076,496 - 25,122,152 (-)NCBIT2T-CHM13v2.0
Kras
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84179,916,255 - 179,949,613 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4179,919,802 - 179,949,320 (-)EnsemblGRCr8
mRatBN7.24178,185,418 - 178,218,484 (-)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx4184,490,327 - 184,516,219 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04180,274,827 - 180,300,720 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04178,895,248 - 178,921,140 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04179,482,562 - 179,515,483 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4179,486,105 - 179,515,558 (-)Ensemblrn6Rnor6.0
Rnor_5.04243,667,912 - 243,696,325 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44182,869,242 - 182,895,106 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4166,708,846 - 166,734,692 (-)NCBICelera
RGSC_v3.14183,114,365 - 183,140,230 (-)NCBI
Cytogenetic Map4q44NCBI
Kras
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541320,298,824 - 20,328,758 (-)Ensembl
ChiLan1.0NW_00495541320,298,852 - 20,328,756 (-)NCBIChiLan1.0ChiLan1.0
KRAS
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21071,565,722 - 71,611,563 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11271,562,118 - 71,607,959 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01261,062,689 - 61,108,524 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11263,679,293 - 63,724,335 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1263,679,293 - 63,724,335 (+)EnsemblpanPan2panpan1.1
KRAS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12722,261,753 - 22,296,704 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2722,257,941 - 22,293,369 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2724,078,345 - 24,117,288 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02722,456,489 - 22,495,435 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2722,456,012 - 22,495,428 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12722,271,689 - 22,310,648 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02722,290,777 - 22,329,504 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02724,245,249 - 24,284,170 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Kras
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494584,156,600 - 84,190,995 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365482,079,036 - 2,110,523 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365482,078,568 - 2,113,877 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KRAS
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl548,508,811 - 48,549,358 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1548,508,774 - 48,546,260 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2552,229,592 - 52,270,153 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KRAS
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11124,963,396 - 25,010,747 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1124,973,619 - 25,005,191 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366606910,116,447 - 10,163,816 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kras
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475213,809,775 - 13,844,166 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462475213,809,741 - 13,847,020 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Kras
1299 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:1616
Count of miRNA genes:678
Interacting mature miRNAs:858
Transcripts:ENSMUST00000032399, ENSMUST00000111710, ENSMUST00000123972, ENSMUST00000149314, ENSMUST00000155145, ENSMUST00000156486
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142079Skmw15_mskeletal muscle weight 15 (mouse)Not determined6116829851149588044Mouse
10043864T2dm4sa_mtype 2 diabetes mellitus 4 in SMXA RI mice (mouse)Not determined683690851146954059Mouse
11252138Clas1_mcarcinogen-induced lung adenoma susceptibility 1 (mouse)6112246918146954059Mouse
10449437Pas15_mpulmonary adenoma susceptibility 15 (mouse)6128180868149588044Mouse
10449436Pas17_mpulmonary adenoma susceptibility 17 (mouse)6124334273145601739Mouse
10449435Pas18_mpulmonary adenoma susceptibility 18 (mouse)6145162425145195965Mouse
1301658Radpf3_mradiation pulmonary fibrosis 3 (mouse)Not determined6115219814146330736Mouse
4141940W6q5_mweight 6 weeks QTL 5 (mouse)Not determined96632912146535124Mouse
4140980Mvwf2_mmodifier of von Willebrand factor 2 (mouse)Not determined114345693145601739Mouse
4141617Ncilt_mnuclear cytoplasmic invaginations in lung tumors (mouse)Not determined145162425145195965Mouse
1301084Bpq5_mblood pressure QTL 5 (mouse)Not determined6129330484149588044Mouse
14746990Manh61_mmandible shape 61 (mouse)6130156355149588044Mouse
4141295Rua_mraffinose acetate tasting (mouse)Not determined115546805149549364Mouse
10766452Sle23_msystematic lupus erythematosus susceptibility 23 (mouse)6128601582149588044Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648696934148351498Mouse
14746999Mancz6_mmandible centroid size 6 (mouse)6130156355149588044Mouse
1302089Wta2_mweight adult 2 (mouse)Not determined6125269523149588044Mouse
1301518Bbaa5_mB.burgdorferi-associated arthritis 5 (mouse)Not determined698483798145881170Mouse
11353842Bmiq4_mbody mass index QTL 4 (mouse)692584287146330736Mouse
4141536Idd6.2_minsulin dependent diabetes susceptibility 6.2 (mouse)Not determined6143556651146215056Mouse
1301686Trmq1_mT cell ratio modifier QTL 1 (mouse)Not determined6129330484149588044Mouse
1357555Tesq2_mtestis weight QTL 2 (mouse)Not determined696632912146535124Mouse
1301620Insq8_minsulin QTL 8 (mouse)Not determined6129534979149588044Mouse
12879916Shm5_msperm head morphology 5 (mouse)6132266532145601739Mouse
10053680Lith25_mlithogenic gene 25 (mouse)Not determined6128601582149588044Mouse
4141974Skmw14_mskeletal muscle weight 14 (mouse)Not determined6129330484149588044Mouse
15092047Wsigrme2_mweek six growth rate, maternal effect 2 (mouse)6140497205147252976Mouse
15092045Wngrme2_mweek nine growth rate, maternal effect 2 (mouse)6140497205147252976Mouse
4142416Egq11_mearly growth QTL 11 (mouse)Not determined96632912146535124Mouse
1301820Mop1_mmorphine preference 1 (mouse)Not determined6132578005146330736Mouse
1301027Hdlq12_mHDL QTL 12 (mouse)Not determined6128601582149588044Mouse
15092052Wsegrme2_mweek seven growth rate, maternal effect 2 (mouse)6140497205147252976Mouse
1301152Athsq2_matherosclerosis susceptibility QTL 2 (mouse)Not determined6117059949149588044Mouse
15092053Wegrme2_mweek eight growth rate, maternal effect 2 (mouse)6140445726147201498Mouse
1301927Etohcta6_methanol conditioned taste aversion 6 (mouse)Not determined6115578005149578150Mouse
4141194Cyx_mcycloheximide tasting (mouse)Not determined115546805149549364Mouse
1558959Eamcd2_mexperimental autoimmune myocarditis 2 (mouse)Not determined6129953954149588044Mouse
15092060Wfogrme1_mweek four growth rate, maternal effect 1 (mouse)6140497205147252976Mouse
15092061Wfigrme1_mweek five growth rate, maternal effect 1 (mouse)6140445726147201498Mouse
15092058Lgrme2_mlate growth rate, maternal effect 2 (mouse)6140497205147252976Mouse
4141889Qui_mquinine sensitivity, taste (mouse)Not determined115546805149549364Mouse
15092056Mgrme1_mmid growth rate, maternal effect 1 (mouse)6140497205147252976Mouse
1301804Bulb2_mbulb size 2 (mouse)Not determined6120416806149588044Mouse

Markers in Region
D6Mit57  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386145,235,142 - 145,235,338UniSTSGRCm38
MGSCv376145,183,662 - 145,183,858UniSTSGRCm37
Celera6148,309,449 - 148,309,647UniSTS
Cytogenetic Map6G2UniSTS
cM Map671.1UniSTS
Whitehead Genetic662.3UniSTS
Whitehead/MRC_RH61458.33UniSTS
Whitehead_YAC6 UniSTS
AI929937  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386145,218,279 - 145,218,427UniSTSGRCm38
MGSCv376145,166,799 - 145,166,947UniSTSGRCm37
Celera6148,292,569 - 148,292,717UniSTS
Cytogenetic Map6G2UniSTS
cM Map671.2UniSTS
Whitehead/MRC_RH61458.43UniSTS
PMC316567P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386145,246,797 - 145,247,199UniSTSGRCm38
MGSCv376145,195,317 - 145,195,719UniSTSGRCm37
Celera6148,321,118 - 148,321,520UniSTS
Cytogenetic Map6G2UniSTS
cM Map671.2UniSTS
Kras2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386145,246,377 - 145,246,552UniSTSGRCm38
MGSCv376145,194,897 - 145,195,072UniSTSGRCm37
Celera6148,320,698 - 148,320,873UniSTS
Cytogenetic Map6G2UniSTS
cM Map671.2UniSTS
Kras2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6G2UniSTS
cM Map671.2UniSTS
Kras2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386145,246,472 - 145,246,805UniSTSGRCm38
MGSCv376145,194,992 - 145,195,325UniSTSGRCm37
Celera6148,320,793 - 148,321,126UniSTS
Cytogenetic Map6G2UniSTS
cM Map671.2UniSTS
Kras2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386145,246,687 - 145,246,818UniSTSGRCm38
MGSCv376145,195,207 - 145,195,338UniSTSGRCm37
Celera6148,321,008 - 148,321,139UniSTS
Cytogenetic Map6G2UniSTS
cM Map671.2UniSTS
Kras2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386145,246,928 - 145,247,108UniSTSGRCm38
MGSCv376145,195,448 - 145,195,628UniSTSGRCm37
Celera6148,321,249 - 148,321,429UniSTS
Cytogenetic Map6G2UniSTS
cM Map671.2UniSTS
Kras2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386145,246,264 - 145,246,548UniSTSGRCm38
MGSCv376145,194,784 - 145,195,068UniSTSGRCm37
Celera6148,320,585 - 148,320,869UniSTS
Cytogenetic Map6G2UniSTS
cM Map671.2UniSTS
Kras2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386145,219,570 - 145,219,680UniSTSGRCm38
MGSCv376145,168,090 - 145,168,200UniSTSGRCm37
Celera6148,293,870 - 148,293,980UniSTS
Cytogenetic Map6G2UniSTS
cM Map671.2UniSTS
Kras2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386145,220,057 - 145,220,250UniSTSGRCm38
MGSCv376145,168,577 - 145,168,770UniSTSGRCm37
Celera6148,294,361 - 148,294,554UniSTS
Cytogenetic Map6G2UniSTS
cM Map671.2UniSTS
Kras2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386145,219,521 - 145,219,688UniSTSGRCm38
MGSCv376145,168,041 - 145,168,208UniSTSGRCm37
Celera6148,293,821 - 148,293,988UniSTS
Cytogenetic Map6G2UniSTS
cM Map671.2UniSTS
Kras  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6G2UniSTS
cM Map671.2UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001403240 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001403241 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001403242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001403243 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001403244 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001403245 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001403246 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_021284 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_175367 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_175368 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006506919 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC157091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK155064 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK164065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY487807 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC004642 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC010202 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC014700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC031623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC119495 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC141051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU207316 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU458742 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JC006855 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  K01927 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M16708 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S39586 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U76425 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U76426 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X00485 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X02452 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X02453 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X02454 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X02455 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X02456 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X15887 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000032399   ⟹   ENSMUSP00000032399
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6145,162,425 - 145,195,965 (-)Ensembl
GRCm38.p6 Ensembl6145,216,699 - 145,250,239 (-)Ensembl
Ensembl Acc Id: ENSMUST00000111710   ⟹   ENSMUSP00000107339
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6145,165,971 - 145,195,903 (-)Ensembl
GRCm38.p6 Ensembl6145,220,245 - 145,250,177 (-)Ensembl
Ensembl Acc Id: ENSMUST00000123972
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6145,165,706 - 145,176,550 (-)Ensembl
GRCm38.p6 Ensembl6145,219,980 - 145,230,824 (-)Ensembl
Ensembl Acc Id: ENSMUST00000149314
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6145,166,336 - 145,171,283 (-)Ensembl
GRCm38.p6 Ensembl6145,220,610 - 145,225,557 (-)Ensembl
Ensembl Acc Id: ENSMUST00000155145   ⟹   ENSMUSP00000118251
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6145,192,430 - 145,195,928 (-)Ensembl
GRCm38.p6 Ensembl6145,246,704 - 145,250,202 (-)Ensembl
Ensembl Acc Id: ENSMUST00000156486   ⟹   ENSMUSP00000119414
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6145,166,023 - 145,195,896 (-)Ensembl
GRCm38.p6 Ensembl6145,220,297 - 145,250,170 (-)Ensembl
Ensembl Acc Id: ENSMUST00000203147   ⟹   ENSMUSP00000145294
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6145,165,947 - 145,195,965 (-)Ensembl
GRCm38.p6 Ensembl6145,220,221 - 145,250,239 (-)Ensembl
RefSeq Acc Id: NM_001403240   ⟹   NP_001390169
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396145,162,429 - 145,197,631 (-)NCBI
RefSeq Acc Id: NM_001403241   ⟹   NP_001390170
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396145,162,429 - 145,195,965 (-)NCBI
RefSeq Acc Id: NM_001403242   ⟹   NP_001390171
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396145,162,429 - 145,195,965 (-)NCBI
RefSeq Acc Id: NM_001403243   ⟹   NP_001390172
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396145,162,429 - 145,195,965 (-)NCBI
RefSeq Acc Id: NM_001403244   ⟹   NP_001390173
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396145,162,429 - 145,197,631 (-)NCBI
RefSeq Acc Id: NM_001403245   ⟹   NP_001390174
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396145,162,429 - 145,195,965 (-)NCBI
RefSeq Acc Id: NM_001403246   ⟹   NP_001390175
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396145,162,429 - 145,195,965 (-)NCBI
RefSeq Acc Id: NM_021284   ⟹   NP_067259
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396145,162,429 - 145,195,965 (-)NCBI
GRCm386145,216,699 - 145,250,231 (-)NCBI
MGSCv376145,165,219 - 145,198,751 (-)RGD
Celera6148,290,985 - 148,324,546 (-)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_175367
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396145,162,429 - 145,195,965 (-)NCBI
RefSeq Acc Id: NR_175368
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396145,162,429 - 145,195,965 (-)NCBI
RefSeq Acc Id: XM_006506919   ⟹   XP_006506982
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396145,162,425 - 145,196,069 (-)NCBI
GRCm386145,216,699 - 145,250,141 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001390169 (Get FASTA)   NCBI Sequence Viewer  
  NP_001390170 (Get FASTA)   NCBI Sequence Viewer  
  NP_001390171 (Get FASTA)   NCBI Sequence Viewer  
  NP_001390172 (Get FASTA)   NCBI Sequence Viewer  
  NP_001390173 (Get FASTA)   NCBI Sequence Viewer  
  NP_001390174 (Get FASTA)   NCBI Sequence Viewer  
  NP_001390175 (Get FASTA)   NCBI Sequence Viewer  
  NP_067259 (Get FASTA)   NCBI Sequence Viewer  
  XP_006506982 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA40037 (Get FASTA)   NCBI Sequence Viewer  
  AAH04642 (Get FASTA)   NCBI Sequence Viewer  
  AAH10202 (Get FASTA)   NCBI Sequence Viewer  
  AAI19496 (Get FASTA)   NCBI Sequence Viewer  
  AAI41052 (Get FASTA)   NCBI Sequence Viewer  
  AAO46052 (Get FASTA)   NCBI Sequence Viewer  
  AAS58056 (Get FASTA)   NCBI Sequence Viewer  
  BAE33023 (Get FASTA)   NCBI Sequence Viewer  
  BAE37609 (Get FASTA)   NCBI Sequence Viewer  
  CAA25160 (Get FASTA)   NCBI Sequence Viewer  
  CAA26295 (Get FASTA)   NCBI Sequence Viewer  
  CAA26296 (Get FASTA)   NCBI Sequence Viewer  
  CAA33897 (Get FASTA)   NCBI Sequence Viewer  
  CDL93478 (Get FASTA)   NCBI Sequence Viewer  
  EDL10686 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000032399
  ENSMUSP00000032399.6
  ENSMUSP00000107339
  ENSMUSP00000107339.2
  ENSMUSP00000145294
GenBank Protein P32883 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_067259   ⟸   NM_021284
- Peptide Label: isoform 1
- UniProtKB: Q5J7N1 (UniProtKB/TrEMBL),   Q3U2W7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006506982   ⟸   XM_006506919
- Peptide Label: isoform X2
- UniProtKB: Q3U2W7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000107339   ⟸   ENSMUST00000111710
Ensembl Acc Id: ENSMUSP00000145294   ⟸   ENSMUST00000203147
Ensembl Acc Id: ENSMUSP00000032399   ⟸   ENSMUST00000032399
Ensembl Acc Id: ENSMUSP00000119414   ⟸   ENSMUST00000156486
Ensembl Acc Id: ENSMUSP00000118251   ⟸   ENSMUST00000155145
RefSeq Acc Id: NP_001390173   ⟸   NM_001403244
- Peptide Label: isoform 3
RefSeq Acc Id: NP_001390169   ⟸   NM_001403240
- Peptide Label: isoform 1
- UniProtKB: Q5J7N1 (UniProtKB/TrEMBL),   Q3U2W7 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001390174   ⟸   NM_001403245
- Peptide Label: isoform 3
RefSeq Acc Id: NP_001390175   ⟸   NM_001403246
- Peptide Label: isoform 4
- UniProtKB: A0A0N4SVY1 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001390172   ⟸   NM_001403243
- Peptide Label: isoform 2
- UniProtKB: P32883 (UniProtKB/Swiss-Prot),   P04200 (UniProtKB/Swiss-Prot),   P08643 (UniProtKB/Swiss-Prot),   Q0VDV7 (UniProtKB/TrEMBL),   A0A0G2JGP4 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001390171   ⟸   NM_001403242
- Peptide Label: isoform 1
- UniProtKB: Q5J7N1 (UniProtKB/TrEMBL),   Q3U2W7 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001390170   ⟸   NM_001403241
- Peptide Label: isoform 1
- UniProtKB: Q5J7N1 (UniProtKB/TrEMBL),   Q3U2W7 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P32883-F1-model_v2 AlphaFold P32883 1-189 view protein structure

Promoters
RGD ID:6839546
Promoter ID:MM_KWN:48206
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_2Hour,   BoneMarrow_4Hour
Transcripts:ENSMUST00000032397,   ENSMUST00000111709,   OTTMUST00000052666,   OTTMUST00000053353,   OTTMUST00000053356,   UC009ERI.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv366145,198,499 - 145,198,999 (-)MPROMDB
RGD ID:6891488
Promoter ID:EPDNEW_M9195
Type:initiation region
Name:Kras_1
Description:Mus musculus Kirsten rat sarcoma viral oncogene homolog , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm386145,250,231 - 145,250,291EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:96680 AgrOrtholog
Ensembl Genes ENSMUSG00000030265 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000032399 ENTREZGENE
  ENSMUST00000032399.12 UniProtKB/Swiss-Prot
  ENSMUST00000111710 ENTREZGENE
  ENSMUST00000111710.8 UniProtKB/Swiss-Prot
  ENSMUST00000203147 ENTREZGENE
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot
InterPro P-loop_NTPase UniProtKB/Swiss-Prot
  Small_GTP-bd_dom UniProtKB/Swiss-Prot
  Small_GTPase UniProtKB/Swiss-Prot
  Small_GTPase_Ras-type UniProtKB/Swiss-Prot
KEGG Report mmu:16653 UniProtKB/Swiss-Prot
MGD MGI:96680 ENTREZGENE
NCBI Gene 16653 ENTREZGENE
PANTHER PTHR24070 UniProtKB/Swiss-Prot
Pfam Ras UniProtKB/Swiss-Prot
PharmGKB KRAS RGD
PhenoGen Kras PhenoGen
PRINTS RASTRNSFRMNG UniProtKB/Swiss-Prot
PROSITE RAS UniProtKB/Swiss-Prot
SMART RAB UniProtKB/Swiss-Prot
  RAN UniProtKB/Swiss-Prot
  RAS UniProtKB/Swiss-Prot
  RHO UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot
UniProt A0A0G2JGP4 ENTREZGENE
  A0A0N4SVY1 ENTREZGENE, UniProtKB/TrEMBL
  B2KGV5_MOUSE UniProtKB/TrEMBL
  E9Q8V2_MOUSE UniProtKB/TrEMBL
  P04200 ENTREZGENE
  P08643 ENTREZGENE
  P32883 ENTREZGENE
  Q0VDV7 ENTREZGENE, UniProtKB/TrEMBL
  Q3U2W7 ENTREZGENE, UniProtKB/TrEMBL
  Q5J7N1 ENTREZGENE, UniProtKB/TrEMBL
  RASK_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary P04200 UniProtKB/Swiss-Prot
  P08643 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-01-05 Kras  Kirsten rat sarcoma viral oncogene homolog    v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog  Symbol and/or name change 5135510 APPROVED