Mstn<sup>em1Cqin</sup> (myostatin; ZFN induced mutant 1, Cqin) - Rat Genome Database

Send us a Message

Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Mstnem1Cqin (myostatin; ZFN induced mutant 1, Cqin) Rattus norvegicus
Symbol: Mstnem1Cqin
Name: myostatin; ZFN induced mutant 1, Cqin
RGD ID: 151347430
Description: A ZFN construct engineered to target bp 277 to 281 of rat Mstn was used for the rat embryo injection. The # 6 founder was found to have sequence changed from GATCA to AGTC, resulting in a frame shift mutation within the open reading frame and generate an early termination codon, resulting in a truncated 109 amino acid peptide (wild type is 376).
ASSOCIATED WITH increased body weight
Type: allele  of Mstn  
Previously known as: Mstn^[em1Cqin]
Is Marker For: Strains:   SD-Mstnem1Cqin  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position: No map positions available.

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

References - curated
# Reference Title Reference Citation
1. Establishment and phenotypic analysis of an Mstn knockout rat. Gu H, etal., Biochem Biophys Res Commun. 2016 Aug 12;477(1):115-22. doi: 10.1016/j.bbrc.2016.06.030. Epub 2016 Jun 8.


Related Rat Strains
The following Strains have been annotated to Mstnem1Cqin



Nucleotide Sequences

Additional Information