Dsg4<sup>hr</sup> (desmoglein 4; hairless mutant) - Rat Genome Database

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Gene: Dsg4hr (desmoglein 4; hairless mutant) Rattus norvegicus
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Symbol: Dsg4hr
Name: desmoglein 4; hairless mutant
RGD ID: 150521603
Description: This Iffa Credo ( IC) hairless mutation was a spontaneous recessive mutant identified in a colony of Crl:OFA(SD) at 1974. A large intracellular out-of-frame deletion in Dsg4 of IC mutant rats was identified. The intragenic deletion spanning exons 2?10 that results in a significant down-regulation of Dsg4 message.
ASSOCIATED WITH alopecia; ASSOCIATED WITH hypotrichosis
Type: allele  of Dsg4  
Previously known as: Dsg4^[hr]
Is Marker For: Strains:   OFA(SD)-Dsg4hr/Crl  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position: No map positions available.


Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
alopecia  (IMP)
References

References - curated
# Reference Title Reference Citation
1. Intragenic deletion in the Desmoglein 4 gene underlies the skin phenotype in the Iffa Credo "hairless" rat. Bazzi H, etal., Differentiation. 2004 Oct;72(8):450-64. doi: 10.1111/j.1432-0436.2004.07208010.x.

Genomics


Related Rat Strains
The following Strains have been annotated to Dsg4hr
OFA(SD)-Dsg4hr/Crl    


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences


Additional Information