Uox<sup>em1Cya</sup> (urate oxidase; CRISPR/Cas9 induced mutant1, Cya) - Rat Genome Database

Send us a Message

Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Uoxem1Cya (urate oxidase; CRISPR/Cas9 induced mutant1, Cya) Rattus norvegicus
Symbol: Uoxem1Cya
Name: urate oxidase; CRISPR/Cas9 induced mutant1, Cya
RGD ID: 150521540
Description: The CRISPR/Cas9 system targeting exons 2 to 4 was injected into Sprague Dawley embryos. The resulting mutation was complete deletion of exons 2, 3 and 4.
ASSOCIATED WITH increased blood urea nitrogen level; increased blood uric acid level; tubulointerstitial nephritis; ASSOCIATED WITH hyperuricemia
Type: allele  of Uox  
Previously known as: Uox^[em1Cya]
Is Marker For: Strains:   SD-Uoxem1Cya  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position: No map positions available.

Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

References - curated
# Reference Title Reference Citation
1. Uricase-deficient rat is generated with CRISPR/Cas9 technique. Yu Y, etal., PeerJ. 2020 Apr 27;8:e8971. doi: 10.7717/peerj.8971. eCollection 2020.


Related Rat Strains
The following Strains have been annotated to Uoxem1Cya



Nucleotide Sequences

Additional Information