Slco1b2<sup>em1Myliu</sup> (solute carrier organic anion transporter family member 1B2; CRISPR/Case9 induced mutant 1, Myliu) - Rat Genome Database

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Gene: Slco1b2em1Myliu (solute carrier organic anion transporter family member 1B2; CRISPR/Case9 induced mutant 1, Myliu) Rattus norvegicus
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Symbol: Slco1b2em1Myliu
Name: solute carrier organic anion transporter family member 1B2; CRISPR/Case9 induced mutant 1, Myliu
RGD ID: 150521524
Description: The Sprague Dawley embryos were injected with CRISPR/Case9 system targeting the first exon of the rat Slco1b2 gene. A Slco1b2 knockout was created with 11-bp deletion.
ASSOCIATED WITH abnormal xenobiotic pharmacokinetics; ASSOCIATED WITH Hereditary Hyperbilirubinemia
Type: allele  of Slco1b2  
Is Marker For: Strains:   SD-Slco1b2em1Myliu  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position: No map positions available.


Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Characterization of organic anion transporting polypeptide 1b2 knockout rats generated by CRISPR/Cas9: a novel model for drug transport and hyperbilirubinemia disease. Ma X, etal., Acta Pharm Sin B. 2020 May;10(5):850-860. doi: 10.1016/j.apsb.2019.11.007. Epub 2019 Nov 14.

Genomics


Related Rat Strains
The following Strains have been annotated to Slco1b2em1Myliu


Expression


Sequence

Nucleotide Sequences


Additional Information