Apoe<sup>em1Ejt</sup> (apolipoprotein E; TALEN induced mutant 1, Ejt) - Rat Genome Database

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Gene: Apoeem1Ejt (apolipoprotein E; TALEN induced mutant 1, Ejt) Rattus norvegicus
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Symbol: Apoeem1Ejt
Name: apolipoprotein E; TALEN induced mutant 1, Ejt
RGD ID: 150520190
Description: The mutant rat strain was produced by injecting TALEN system targeting the exon 4 of rat Apoe into Sprague Dawley (Hsd:SD) embryos. This mutant rat has a 16-bp deletion in the gene third coding exon) located on chromosome 1; frameshift mutation resulted (p.Glu178fs)
ASSOCIATED WITH abnormal aorta morphology; increased systemic arterial blood pressure; ASSOCIATED WITH familial hypercholesterolemia
Type: allele  of Apoe  
Previously known as: Apoe^[em1Ejt]
Is Marker For: Strains:   SD-Apoeem1Ejt  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position: No map positions available.


Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Angiotensin II Infusion Does Not Cause Abdominal Aortic Aneurysms in Apolipoprotein E-Deficient Rats. Phillips EH, etal., J Vasc Res. 2018;55(1):1-12. doi: 10.1159/000484086. Epub 2017 Nov 23.

Genomics


Related Rat Strains
The following Strains have been annotated to Apoeem1Ejt
SD-Apoeem1Ejt    


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences


Additional Information