Cyp2c11<sup>em1Nju</sup> (cytochrome P450, subfamily 2, polypeptide 11; CRISPR/Cas9 induced mutant 1, Nju) - Rat Genome Database

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Gene: Cyp2c11em1Nju (cytochrome P450, subfamily 2, polypeptide 11; CRISPR/Cas9 induced mutant 1, Nju) Rattus norvegicus
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Symbol: Cyp2c11em1Nju
Name: cytochrome P450, subfamily 2, polypeptide 11; CRISPR/Cas9 induced mutant 1, Nju
RGD ID: 150429708
Description: This allele was created by CRISPR/Cas9 system in the Sprague-Dawley embryo. The mutant allele carries a two base pairs (GT) insertion into exon 6 of CYP2C11 and resulting in the knockout allele.
ASSOCIATED WITH abnormal xenobiotic pharmacokinetics; decreased litter size; delayed fertility
Type: allele  of Cyp2c11  
Previously known as: Cyp2c11^[em1Nju]
Is Marker For: Strains:   SD-Cyp2c11em1Nju  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position: No map positions available.


Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Generation and Characterization of a CYP2C11-Null Rat Model by Using the CRISPR/Cas9 Method. Wei Y, etal., Drug Metab Dispos. 2018 May;46(5):525-531. doi: 10.1124/dmd.117.078444. Epub 2018 Feb 14.

Genomics


Related Rat Strains
The following Strains have been annotated to Cyp2c11em1Nju


Expression


Sequence

Nucleotide Sequences


Additional Information