Dnd1<sup>ter</sup> (DND microRNA-mediated repression inhibitor 1, ter mutant) - Rat Genome Database

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Gene: Dnd1ter (DND microRNA-mediated repression inhibitor 1, ter mutant) Rattus norvegicus
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Symbol: Dnd1ter
Name: DND microRNA-mediated repression inhibitor 1, ter mutant
RGD ID: 150340622
Description: This is a spontaneous mutation (ter) allele leading to the formation of congenital ovarian and testicular tumorsin the WKY/Ztm rat strain. Sequence analysis detected a point mutation in exon 4 of the rat Dnd1, which introduces a premature stop codon assumed to cause a truncation of the Dnd1 protein.
ASSOCIATED WITH abnormal spermatogenesis; absent germ cells; decreased ovary weight; ASSOCIATED WITH teratocarcinoma
Type: allele  of Dnd1  
Is Marker For: Strains:   WKY-Dnd1ter/Ztm  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position: No map positions available.


Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. The ter mutation in the rat Dnd1 gene initiates gonadal teratomas and infertility in both genders. Northrup E, etal., PLoS One. 2012;7(5):e38001. doi: 10.1371/journal.pone.0038001. Epub 2012 May 24.

Genomics


Related Rat Strains
The following Strains have been annotated to Dnd1ter
WKY-Dnd1ter/Ztm    


Expression


Sequence

Nucleotide Sequences


Additional Information