GPX5 (glutathione peroxidase 5) - Rat Genome Database

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Gene: GPX5 (glutathione peroxidase 5) Sus scrofa
Analyze
Symbol: GPX5
Name: glutathione peroxidase 5
RGD ID: 14293205
Description: ENCODES a protein that exhibits glutathione peroxidase activity (inferred); peroxidase activity (inferred); INVOLVED IN cellular response to oxidative stress (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); megacolon (ortholog); FOUND IN extracellular space (ortholog); sperm plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: EGLP; epididymal secretory glutathione peroxidase; epididymis-specific glutathione peroxidase 23kDa subunit; epididymis-specific glutathione peroxidase-like protein; glutathione peroxidase 5 (epididymal androgen-related protein); GPx-5; GSHPx-5
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl722,291,986 - 22,300,727 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1722,289,432 - 22,300,727 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2724,233,520 - 24,244,829 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:9271255   PMID:22301074   PMID:26711247   PMID:30032202  


Genomics

Comparative Map Data
GPX5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl722,291,986 - 22,300,727 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1722,289,432 - 22,300,727 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2724,233,520 - 24,244,829 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GPX5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38628,525,881 - 28,534,955 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl628,525,881 - 28,534,955 (+)EnsemblGRCh38hg38GRCh38
GRCh37628,493,658 - 28,502,732 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36628,601,768 - 28,609,923 (+)NCBINCBI36Build 36hg18NCBI36
Build 34628,601,767 - 28,609,923NCBI
Celera630,100,218 - 30,109,121 (+)NCBICelera
Cytogenetic Map6p22.1NCBI
HuRef628,300,120 - 28,309,014 (+)NCBIHuRef
CHM1_1628,496,188 - 28,505,099 (+)NCBICHM1_1
T2T-CHM13v2.0628,397,310 - 28,406,348 (+)NCBIT2T-CHM13v2.0
Gpx5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391321,470,599 - 21,476,897 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1321,470,599 - 21,476,901 (-)EnsemblGRCm39 Ensembl
GRCm381321,286,429 - 21,292,727 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1321,286,429 - 21,292,731 (-)EnsemblGRCm38mm10GRCm38
MGSCv371321,378,298 - 21,384,555 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361321,293,898 - 21,300,151 (-)NCBIMGSCv36mm8
Celera1321,553,579 - 21,559,835 (-)NCBICelera
Cytogenetic Map13A3.1NCBI
cM Map137.73NCBI
Gpx5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81748,131,853 - 48,138,801 (+)NCBIGRCr8
mRatBN7.21743,436,126 - 43,443,074 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1743,416,340 - 43,443,074 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1745,493,484 - 45,500,432 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01750,252,586 - 50,259,534 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01744,743,174 - 44,750,131 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01745,508,657 - 45,518,686 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1745,467,015 - 45,518,686 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01757,952,807 - 57,962,120 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.11751,091,844 - 51,098,176 (+)NCBI
Celera1753,035,706 - 53,042,631 (-)NCBICelera
Cytogenetic Map17q11NCBI
GPX5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2543,153,860 - 43,162,096 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1639,154,800 - 39,163,014 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0628,340,291 - 28,348,504 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1629,010,528 - 29,018,737 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl629,010,528 - 29,018,737 (+)Ensemblpanpan1.1panPan2
GPX5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13525,653,627 - 25,662,490 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3525,653,615 - 25,662,490 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3525,512,937 - 25,521,120 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03525,952,095 - 25,960,969 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3525,952,083 - 25,960,969 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13525,615,767 - 25,624,631 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03525,671,318 - 25,679,525 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03527,140,044 - 27,148,915 (+)NCBIUU_Cfam_GSD_1.0
Gpx5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494628,952,020 - 28,961,691 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936914487,163 - 496,465 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GPX5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11744,027,538 - 44,037,304 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1744,028,543 - 44,036,686 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604428,225,741 - 28,234,766 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in GPX5
268 total Variants

Expression

RNA-SEQ Expression

mesenchyme
mesoderm
renal system
reproductive system
1 1 1 1

Sequence


Ensembl Acc Id: ENSSSCT00000001312   ⟹   ENSSSCP00000001283
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl722,291,986 - 22,300,727 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000084141   ⟹   ENSSSCP00000073783
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl722,289,407 - 22,298,255 (+)Ensembl
RefSeq Acc Id: NM_213886   ⟹   NP_999051
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1722,289,432 - 22,300,727 (+)NCBI
Sequence:
RefSeq Acc Id: NP_999051   ⟸   NM_213886
- Peptide Label: precursor
- UniProtKB: O18994 (UniProtKB/Swiss-Prot),   A0A900NI31 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000001283   ⟸   ENSSSCT00000001312
Ensembl Acc Id: ENSSSCP00000073783   ⟸   ENSSSCT00000084141


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000001214 Ensembl, UniProtKB/TrEMBL
  ENSSSCG00005002918 UniProtKB/Swiss-Prot
  ENSSSCG00015054484 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00025073518 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00030025829 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00035029146 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00040005331 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00045007605 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00050031364 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00055006273 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00060030030 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00065021191 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00070024870 UniProtKB/Swiss-Prot
Ensembl Transcript ENSSSCT00000001312.5 UniProtKB/TrEMBL
  ENSSSCT00005004486 UniProtKB/Swiss-Prot
  ENSSSCT00015072658.1 UniProtKB/Swiss-Prot
  ENSSSCT00015072897.1 UniProtKB/TrEMBL
  ENSSSCT00025101197.1 UniProtKB/TrEMBL
  ENSSSCT00025101265.1 UniProtKB/Swiss-Prot
  ENSSSCT00030036072.1 UniProtKB/Swiss-Prot
  ENSSSCT00030036095.1 UniProtKB/TrEMBL
  ENSSSCT00035038572.1 UniProtKB/TrEMBL
  ENSSSCT00035038593.1 UniProtKB/Swiss-Prot
  ENSSSCT00040007052.1 UniProtKB/Swiss-Prot
  ENSSSCT00040007063.1 UniProtKB/TrEMBL
  ENSSSCT00045012696.1 UniProtKB/Swiss-Prot
  ENSSSCT00045012738.1 UniProtKB/TrEMBL
  ENSSSCT00050042167.1 UniProtKB/Swiss-Prot
  ENSSSCT00050042182.1 UniProtKB/TrEMBL
  ENSSSCT00055012155.1 UniProtKB/TrEMBL
  ENSSSCT00055012184.1 UniProtKB/Swiss-Prot
  ENSSSCT00060040551.1 UniProtKB/TrEMBL
  ENSSSCT00060040554.1 UniProtKB/Swiss-Prot
  ENSSSCT00065028217.1 UniProtKB/Swiss-Prot
  ENSSSCT00065028222.1 UniProtKB/TrEMBL
  ENSSSCT00070049697.1 UniProtKB/Swiss-Prot
Gene3D-CATH Glutaredoxin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Glutathione_peroxidase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPX_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPX_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thioredoxin-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:396920 UniProtKB/Swiss-Prot
NCBI Gene GPX5 ENTREZGENE
PANTHER EPIDIDYMAL SECRETORY GLUTATHIONE PEROXIDASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GLUTATHIONE PEROXIDASE UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
Pfam GSHPx UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PIRSF Glutathion_perox UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS GLUTPROXDASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE GLUTATHIONE_PEROXID_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GLUTATHIONE_PEROXID_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GLUTATHIONE_PEROXID_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52833 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8D0ZHM9_PIG UniProtKB/TrEMBL
  A0A900NI31 ENTREZGENE, UniProtKB/TrEMBL
  GPX5_PIG UniProtKB/Swiss-Prot, ENTREZGENE
  Q9TTE3_PIG UniProtKB/TrEMBL