TCP1 (t-complex 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: TCP1 (t-complex 1) Sus scrofa
Analyze
Symbol: TCP1
Name: t-complex 1
RGD ID: 14288391
Description: ENCODES a protein that exhibits acyltransferase activity (inferred); ATP binding (inferred); ATP hydrolysis activity (inferred); INVOLVED IN positive regulation of protein localization to Cajal body (ortholog); ASSOCIATED WITH 3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like syndrome (ortholog); INTELLECTUAL DEVELOPMENTAL DISORDER WITH POLYMICROGYRIA AND SEIZURES (ortholog); Prostatic Neoplasms (ortholog); FOUND IN heterochromatin (ortholog); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: T-complex protein 1 subunit alpha
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl17,590,140 - 7,601,795 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.117,590,140 - 7,600,709 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.219,389,098 - 9,399,667 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
TCP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl17,590,140 - 7,601,795 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.117,590,140 - 7,600,709 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.219,389,098 - 9,399,667 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TCP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386159,778,498 - 159,789,602 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6159,778,498 - 159,789,703 (-)EnsemblGRCh38hg38GRCh38
GRCh376160,199,530 - 160,210,634 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366160,119,520 - 160,130,725 (-)NCBINCBI36Build 36hg18NCBI36
Build 346160,169,941 - 160,181,146NCBI
Celera6160,845,607 - 160,856,819 (-)NCBICelera
Cytogenetic Map6q25.3NCBI
HuRef6157,669,773 - 157,680,978 (-)NCBIHuRef
CHM1_16160,461,821 - 160,473,042 (-)NCBICHM1_1
T2T-CHM13v2.06161,024,115 - 161,035,234 (-)NCBIT2T-CHM13v2.0
Tcp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391713,135,216 - 13,143,954 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1713,134,588 - 13,143,954 (+)EnsemblGRCm39 Ensembl
GRCm381712,916,329 - 12,925,067 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1712,915,701 - 12,925,067 (+)EnsemblGRCm38mm10GRCm38
MGSCv371713,109,331 - 13,117,933 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361712,759,446 - 12,767,497 (+)NCBIMGSCv36mm8
Celera1712,948,013 - 12,956,616 (+)NCBICelera
Cytogenetic Map17A1NCBI
cM Map178.72NCBI
Tcp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8150,376,848 - 50,384,527 (-)NCBIGRCr8
mRatBN7.2147,829,061 - 47,836,809 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl147,828,652 - 47,836,839 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx148,520,703 - 48,528,382 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0154,506,599 - 54,514,346 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0148,596,232 - 48,603,911 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0148,025,664 - 48,033,343 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl148,025,663 - 48,033,396 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0151,719,055 - 51,726,734 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4142,103,543 - 42,111,222 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1142,106,487 - 42,114,167 (-)NCBI
Celera143,629,524 - 43,637,203 (-)NCBICelera
RH 3.4 Map1537.31RGD
Cytogenetic Map1q11NCBI
Tcp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495543921,114,038 - 21,124,379 (+)NCBIChiLan1.0ChiLan1.0
TCP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25179,877,363 - 179,888,668 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16177,781,864 - 177,793,622 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06157,661,409 - 157,672,581 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16162,673,050 - 162,684,261 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6162,673,596 - 162,683,985 (-)Ensemblpanpan1.1panPan2
TCP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1149,029,260 - 49,038,023 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl149,029,282 - 49,038,020 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha149,871,249 - 49,879,992 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0149,213,974 - 49,222,681 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl149,213,961 - 49,222,697 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1149,096,311 - 49,105,058 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0148,967,408 - 48,976,160 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0149,582,581 - 49,591,336 (-)NCBIUU_Cfam_GSD_1.0
Tcp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946144,021,338 - 144,030,784 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493648911,273,335 - 11,282,811 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TCP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11387,377,452 - 87,388,692 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1387,377,996 - 87,388,568 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604059,776,464 - 59,787,759 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tcp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248553,121,274 - 3,133,640 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in TCP1
442 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000004476   ⟹   ENSSSCP00000004374
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl17,590,225 - 7,601,795 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000042694   ⟹   ENSSSCP00000044537
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl17,590,270 - 7,600,703 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000049476   ⟹   ENSSSCP00000054550
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl17,590,140 - 7,600,424 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000065084   ⟹   ENSSSCP00000044318
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl17,590,301 - 7,601,795 (+)Ensembl
RefSeq Acc Id: NM_001243427   ⟹   NP_001230356
RefSeq Status: VALIDATED
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.117,590,140 - 7,600,709 (+)NCBI
Sequence:
RefSeq Acc Id: NP_001230356   ⟸   NM_001243427
- UniProtKB: A0A8D1SZI5 (UniProtKB/TrEMBL),   A0A8D1R1C4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000054550   ⟸   ENSSSCT00000049476
Ensembl Acc Id: ENSSSCP00000044318   ⟸   ENSSSCT00000065084
Ensembl Acc Id: ENSSSCP00000044537   ⟸   ENSSSCT00000042694
Ensembl Acc Id: ENSSSCP00000004374   ⟸   ENSSSCT00000004476


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000004048 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015034440 UniProtKB/TrEMBL
  ENSSSCG00025043115 UniProtKB/TrEMBL
  ENSSSCG00030052101 UniProtKB/TrEMBL
  ENSSSCG00035063146 UniProtKB/TrEMBL
  ENSSSCG00040014529 UniProtKB/TrEMBL
  ENSSSCG00045017822 UniProtKB/TrEMBL
  ENSSSCG00055018761 UniProtKB/TrEMBL
  ENSSSCG00060016270 UniProtKB/TrEMBL
  ENSSSCG00065050312 UniProtKB/TrEMBL
  ENSSSCG00070026927 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000004476 ENTREZGENE
  ENSSSCT00000004476.4 UniProtKB/TrEMBL
  ENSSSCT00000042694.2 UniProtKB/TrEMBL
  ENSSSCT00000049476.3 UniProtKB/TrEMBL
  ENSSSCT00000065084.3 UniProtKB/TrEMBL
  ENSSSCT00015046285.1 UniProtKB/TrEMBL
  ENSSSCT00025059029.1 UniProtKB/TrEMBL
  ENSSSCT00030072592.1 UniProtKB/TrEMBL
  ENSSSCT00035084906.1 UniProtKB/TrEMBL
  ENSSSCT00040019530.1 UniProtKB/TrEMBL
  ENSSSCT00045030363.1 UniProtKB/TrEMBL
  ENSSSCT00055036927.1 UniProtKB/TrEMBL
  ENSSSCT00055037067.1 UniProtKB/TrEMBL
  ENSSSCT00060021754.1 UniProtKB/TrEMBL
  ENSSSCT00060021761.1 UniProtKB/TrEMBL
  ENSSSCT00060021805.1 UniProtKB/TrEMBL
  ENSSSCT00060021821.1 UniProtKB/TrEMBL
  ENSSSCT00060021835.1 UniProtKB/TrEMBL
  ENSSSCT00065068929.1 UniProtKB/TrEMBL
  ENSSSCT00065068939.1 UniProtKB/TrEMBL
  ENSSSCT00065069005.1 UniProtKB/TrEMBL
  ENSSSCT00065069016.1 UniProtKB/TrEMBL
  ENSSSCT00070054033.1 UniProtKB/TrEMBL
  ENSSSCT00070054037.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.560.10 UniProtKB/TrEMBL
  3.30.260.10 UniProtKB/TrEMBL
  3.40.47.10 UniProtKB/TrEMBL
  3.50.7.10 UniProtKB/TrEMBL
InterPro Chap_CCT_alpha UniProtKB/TrEMBL
  Chaperone_TCP-1 UniProtKB/TrEMBL
  Chaperonin_TCP-1_CS UniProtKB/TrEMBL
  Cpn60/TCP-1 UniProtKB/TrEMBL
  GroEL-like_apical_dom_sf UniProtKB/TrEMBL
  GROEL-like_equatorial_sf UniProtKB/TrEMBL
  TCP-1-like_intermed_sf UniProtKB/TrEMBL
  TCP-1_chaperonin UniProtKB/TrEMBL
  thermosome_alpha UniProtKB/TrEMBL
  Thiolase-like UniProtKB/TrEMBL
KEGG Report ssc:100153485 UniProtKB/TrEMBL
NCBI Gene TCP1 ENTREZGENE
PANTHER PTHR11353 UniProtKB/TrEMBL
Pfam Cpn60_TCP1 UniProtKB/TrEMBL
PRINTS TCOMPLEXTCP1 UniProtKB/TrEMBL
PROSITE TCP1_1 UniProtKB/TrEMBL
  TCP1_2 UniProtKB/TrEMBL
  TCP1_3 UniProtKB/TrEMBL
Superfamily-SCOP SSF48592 UniProtKB/TrEMBL
  SSF52029 UniProtKB/TrEMBL
  SSF54849 UniProtKB/TrEMBL
UniProt A0A287AJY2_PIG UniProtKB/TrEMBL
  A0A4X1VQF5_PIG UniProtKB/TrEMBL
  A0A4X1VUV5_PIG UniProtKB/TrEMBL
  A0A4X1VW06_PIG UniProtKB/TrEMBL
  A0A8D0IQC1_PIG UniProtKB/TrEMBL
  A0A8D1DJI5_PIG UniProtKB/TrEMBL
  A0A8D1R1C4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1SZI5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1T4P2_PIG UniProtKB/TrEMBL
  A0A8D1T6U7_PIG UniProtKB/TrEMBL
  A0A8D1UJG4_PIG UniProtKB/TrEMBL
UniProt Secondary A0A287AKV4 UniProtKB/TrEMBL
  A0A287BDF2 UniProtKB/TrEMBL
  F1SB63 UniProtKB/TrEMBL
VGNC ID VGNC:93832 ENTREZGENE