GNG8 (G protein subunit gamma 8) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: GNG8 (G protein subunit gamma 8) Sus scrofa
Analyze
Symbol: GNG8
Name: G protein subunit gamma 8
RGD ID: 14242929
Description: ENCODES a protein that exhibits G-protein beta-subunit binding (inferred); INVOLVED IN cellular response to pheromone (ortholog); nervous system development (ortholog); nose development (ortholog); ASSOCIATED WITH liver disease (ortholog); long QT syndrome 1 (ortholog); Walker-Warburg syndrome (ortholog); FOUND IN heterotrimeric G-protein complex (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl652,534,662 - 52,536,414 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1652,534,952 - 52,541,115 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2647,854,442 - 47,861,734 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
GNG8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl652,534,662 - 52,536,414 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1652,534,952 - 52,541,115 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2647,854,442 - 47,861,734 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GNG8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381946,633,953 - 46,639,326 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1946,633,953 - 46,636,541 (-)EnsemblGRCh38hg38GRCh38
GRCh371947,137,210 - 47,139,459 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361951,829,173 - 51,829,779 (-)NCBINCBI36Build 36hg18NCBI36
Build 341951,829,172 - 51,829,779NCBI
Celera1943,940,858 - 43,941,464 (-)NCBICelera
Cytogenetic Map19q13.32NCBI
HuRef1943,562,343 - 43,562,949 (-)NCBIHuRef
CHM1_11947,139,178 - 47,139,784 (-)NCBICHM1_1
T2T-CHM13v2.01949,459,562 - 49,464,865 (-)NCBIT2T-CHM13v2.0
Gng8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39716,625,687 - 16,629,361 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl716,625,711 - 16,629,361 (+)EnsemblGRCm39 Ensembl
GRCm38716,891,737 - 16,895,451 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl716,891,786 - 16,895,436 (+)EnsemblGRCm38mm10GRCm38
MGSCv37717,477,135 - 17,480,784 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36716,050,308 - 16,053,957 (+)NCBIMGSCv36mm8
Celera714,098,204 - 14,101,853 (+)NCBICelera
Cytogenetic Map7A2NCBI
cM Map79.15NCBI
Gng8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8186,692,609 - 86,696,463 (+)NCBIGRCr8
mRatBN7.2177,564,512 - 77,568,371 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl177,564,515 - 77,568,371 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx182,946,593 - 82,948,429 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0191,510,638 - 91,512,474 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0184,701,683 - 84,703,519 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0178,818,360 - 78,822,224 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl178,818,404 - 78,822,224 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0180,065,774 - 80,069,629 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4177,221,378 - 77,223,313 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1177,299,411 - 77,301,424 (+)NCBI
Celera172,050,870 - 72,053,464 (+)NCBICelera
Cytogenetic Map1q21NCBI
Gng8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955574697,254 - 699,282 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955574697,254 - 699,282 (-)NCBIChiLan1.0ChiLan1.0
GNG8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22052,783,979 - 52,795,059 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11954,654,750 - 54,668,068 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01943,626,498 - 43,637,618 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11952,155,081 - 52,157,058 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1952,155,081 - 52,156,410 (-)Ensemblpanpan1.1panPan2
GNG8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11109,266,884 - 109,268,515 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1109,268,056 - 109,268,453 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1108,744,363 - 108,747,819 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01109,791,074 - 109,794,528 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1109,794,069 - 109,794,466 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11109,468,171 - 109,471,624 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01109,102,370 - 109,105,802 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01109,971,075 - 109,974,533 (+)NCBIUU_Cfam_GSD_1.0
Gng8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934918,877,671 - 18,881,455 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936664495,810 - 497,394 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936664495,823 - 496,296 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GNG8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1639,989,915 - 39,995,714 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl639,989,903 - 39,990,910 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607319,701,879 - 19,707,655 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gng8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248326,937,339 - 6,940,735 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248326,937,309 - 6,941,101 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in GNG8
70 total Variants

Expression

RNA-SEQ Expression

ectoderm
endocrine system
mesenchyme
mesoderm
nervous system
reproductive system
7 1 1 2 7 1

Sequence


Ensembl Acc Id: ENSSSCT00000031663   ⟹   ENSSSCP00000025202
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl652,534,662 - 52,536,414 (-)Ensembl
RefSeq Acc Id: XM_005664617   ⟹   XP_005664674
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1652,534,954 - 52,540,782 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021094610   ⟹   XP_020950269
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1652,534,954 - 52,540,782 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021094611   ⟹   XP_020950270
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1652,534,954 - 52,540,782 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021094612   ⟹   XP_020950271
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1652,534,954 - 52,540,782 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021094613   ⟹   XP_020950272
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1652,534,954 - 52,536,232 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021094614   ⟹   XP_020950273
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1652,534,954 - 52,540,782 (-)NCBI
Sequence:
RefSeq Acc Id: XR_001309119
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1652,534,952 - 52,540,782 (-)NCBI
Sequence:
RefSeq Acc Id: XR_001309120
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1652,534,952 - 52,541,115 (-)NCBI
Sequence:
RefSeq Acc Id: XP_020950273   ⟸   XM_021094614
- Peptide Label: isoform X3
- UniProtKB: A0A4X1W0W7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020950271   ⟸   XM_021094612
- Peptide Label: isoform X3
- UniProtKB: A0A4X1W0W7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020950270   ⟸   XM_021094611
- Peptide Label: isoform X3
- UniProtKB: A0A4X1W0W7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020950269   ⟸   XM_021094610
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_005664674   ⟸   XM_005664617
- Peptide Label: isoform X1
- UniProtKB: I3LM81 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020950272   ⟸   XM_021094613
- Peptide Label: isoform X3
- UniProtKB: A0A4X1W0W7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000025202   ⟸   ENSSSCT00000031663
Protein Domains
G protein gamma


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000022068 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015074377 UniProtKB/TrEMBL
  ENSSSCG00025018357 UniProtKB/TrEMBL
  ENSSSCG00035059668 UniProtKB/TrEMBL
  ENSSSCG00040070924 UniProtKB/TrEMBL
  ENSSSCG00045036796 UniProtKB/TrEMBL
  ENSSSCG00050008244 UniProtKB/TrEMBL
  ENSSSCG00055007082 UniProtKB/TrEMBL
  ENSSSCG00060010750 UniProtKB/TrEMBL
  ENSSSCG00065005007 UniProtKB/TrEMBL
  ENSSSCG00070028192 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000031663 ENTREZGENE
  ENSSSCT00000031663.4 UniProtKB/TrEMBL
  ENSSSCT00015100088.1 UniProtKB/TrEMBL
  ENSSSCT00025024887.1 UniProtKB/TrEMBL
  ENSSSCT00035079961.1 UniProtKB/TrEMBL
  ENSSSCT00040097427.1 UniProtKB/TrEMBL
  ENSSSCT00045063365.1 UniProtKB/TrEMBL
  ENSSSCT00050011230.1 UniProtKB/TrEMBL
  ENSSSCT00055013725.1 UniProtKB/TrEMBL
  ENSSSCT00060013973.1 UniProtKB/TrEMBL
  ENSSSCT00065006823.1 UniProtKB/TrEMBL
  ENSSSCT00070056557.1 UniProtKB/TrEMBL
Gene3D-CATH 4.10.260.10 UniProtKB/TrEMBL
InterPro G-protein_gamma-like_dom UniProtKB/TrEMBL
  GGL_sf UniProtKB/TrEMBL
  Gprotein-gamma UniProtKB/TrEMBL
NCBI Gene GNG8 ENTREZGENE
PANTHER PTHR13809 UniProtKB/TrEMBL
Pfam G-gamma UniProtKB/TrEMBL
PRINTS GPROTEING UniProtKB/TrEMBL
PROSITE G_PROTEIN_GAMMA UniProtKB/TrEMBL
SMART G_gamma UniProtKB/TrEMBL
  GGL UniProtKB/TrEMBL
Superfamily-SCOP SSF48670 UniProtKB/TrEMBL
UniProt A0A4X1W0W7 ENTREZGENE, UniProtKB/TrEMBL
  I3LM81 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:88538 ENTREZGENE