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Gene: IAPP (islet amyloid polypeptide) Sus scrofa

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Symbol:

IAPP

Name:

islet amyloid polypeptide

RGD ID:

14240913

Description:

ENCODES a protein that exhibits identical protein binding; hormone activity (ortholog); lipid binding (ortholog); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); amylin receptor 1 signaling pathway (ortholog); amylin receptor 2 signaling pathway (ortholog); ASSOCIATED WITH Experimental Diabetes Mellitus (ortholog); gastric ulcer (ortholog); type 1 diabetes mellitus (ortholog); FOUND IN extracellular space (ortholog); inclusion body (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

Amylin

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	52,046,573 - 52,050,446 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	5	52,046,570 - 52,051,475 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	55,323,381 - 55,327,437 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Experimental Diabetes Mellitus (ISO)

gastric ulcer (ISO)

type 1 diabetes mellitus (ISO)

type 2 diabetes mellitus (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adenylate cyclase-activating G protein-coupled receptor signaling pathway (ISO)

amylin receptor 1 signaling pathway (ISO)

amylin receptor 2 signaling pathway (ISO)

amylin receptor 3 signaling pathway (ISO)

amylin receptor signaling pathway (ISO,ISS)

amyloid fibril formation (ISO)

bone resorption (ISO)

eating behavior (ISO)

negative regulation of bone resorption (ISO)

negative regulation of cell population proliferation (ISO)

negative regulation of osteoclast differentiation (ISO)

osteoclast differentiation (ISO)

positive regulation of calcium-mediated signaling (ISO)

positive regulation of cAMP/PKA signal transduction (ISO)

positive regulation of ERK1 and ERK2 cascade (ISO)

positive regulation of gene expression (ISO)

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (ISO)

protein destabilization (ISO)

protein homooligomerization (ISO)

sensory perception of pain (ISO)

signal transduction (IEA)

Cellular Component

extracellular region (IEA)

extracellular space (ISO)

inclusion body (ISO)

Molecular Function

hormone activity (IEA,ISS)

identical protein binding (IPI)

lipid binding (ISO)

protein binding (ISO)

receptor ligand activity (ISS)

signaling receptor binding (ISO)

References

Additional References at PubMed

PMID:20160085	PMID:21130765	PMID:22301074	PMID:30032202	PMID:37126782

Genomics

Comparative Map Data

IAPP
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	52,046,573 - 52,050,446 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	5	52,046,570 - 52,051,475 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	55,323,381 - 55,327,437 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

IAPP
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	21,354,959 - 21,379,980 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	21,354,959 - 21,379,980 (+)	Ensembl			hg38	GRCh38
GRCh37	12	21,507,893 - 21,532,914 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	21,417,085 - 21,423,683 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	12	21,417,084 - 21,423,683	NCBI
Celera	12	26,681,196 - 26,688,308 (+)	NCBI		Celera
Cytogenetic Map	12	p12.1	NCBI
HuRef	12	21,299,907 - 21,307,017 (+)	NCBI		HuRef
CHM1_1	12	21,491,270 - 21,498,381 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	12	21,233,632 - 21,258,654 (+)	NCBI		T2T-CHM13v2.0

Iapp
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	142,244,151 - 142,249,546 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	142,244,149 - 142,249,687 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	6	142,298,425 - 142,303,820 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	142,298,423 - 142,303,961 (+)	Ensembl			mm10	GRCm38
MGSCv37	6	142,246,945 - 142,252,340 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	6	142,255,650 - 142,261,039 (+)	NCBI		MGSCv36	mm8
Celera	6	145,357,925 - 145,363,320 (+)	NCBI		Celera
Cytogenetic Map	6	G2	NCBI
cM Map	6	73.81	NCBI

Iapp
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	176,968,097 - 176,975,363 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	4	176,968,097 - 176,975,363 (+)	Ensembl				GRCr8
mRatBN7.2	4	175,237,107 - 175,244,373 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	175,237,115 - 175,242,920 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	4	181,532,318 - 181,537,233 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	177,316,585 - 177,321,500 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	175,937,142 - 175,942,057 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	176,509,863 - 176,517,903 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	176,510,696 - 176,516,083 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	4	240,723,950 - 240,731,446 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	4	179,855,956 - 179,860,871 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	4	163,770,383 - 163,775,298 (+)	NCBI		Celera
RGSC_v3.1	4	180,100,696 - 180,106,512 (+)	NCBI
RH 3.4 Map	4	1043.4	RGD
Cytogenetic Map	4	q44	NCBI

Iapp
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955413	16,835,037 - 16,840,682 (-)	Ensembl
ChiLan1.0	NW_004955413	16,834,940 - 16,841,071 (-)	NCBI	ChiLan1.0	ChiLan1.0

IAPP
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	75,425,109 - 75,432,306 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	75,421,507 - 75,428,704 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	64,918,000 - 64,925,191 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	67,520,986 - 67,528,103 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	67,520,986 - 67,528,103 (-)	Ensembl			panPan2	panpan1.1

IAPP
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	27	26,295,481 - 26,299,967 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	27	26,295,481 - 26,299,967 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	27	20,156,535 - 20,161,021 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	27	26,621,265 - 26,625,751 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	27	26,621,265 - 26,625,751 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	27	26,484,470 - 26,488,955 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	27	26,462,824 - 26,467,310 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	27	19,861,411 - 19,865,898 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Iapp
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	87,540,811 - 87,546,687 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936548	5,463,828 - 5,469,139 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936548	5,463,829 - 5,469,136 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

IAPP
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	21,240,947 - 21,247,409 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	21,241,514 - 21,247,207 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666069	13,897,267 - 13,904,564 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Iapp
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624752	17,584,225 - 17,593,693 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624752	17,528,214 - 17,594,622 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Variants

Variants in IAPP
95 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	hemolymphoid system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
4	1	21	1	2	2	3	21	1	3	1

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003126437	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_002344089	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000034	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU633485	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GU396090	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U62628	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSSCT00000059687 ⟹ ENSSSCP00000046960

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	5	52,046,006 - 52,050,525 (-)	Ensembl

RefSeq Acc Id:

XM_003126437 ⟹ XP_003126485

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	5	52,046,570 - 52,050,494 (-)	NCBI

Sequence:

show sequence

AGCTGGGAAAGGTGTGAAGGGTATACACGAGCTAGATTACTGGTTAGCAAGTCTGGGGTAAATG
TTCCAGTGGATGCAAGCTTGGGATTTTTCATGGAGCTTCTTTGCTATCAAAGGCATTTTCTGAT
AGAGCTGACACTGAGACATTAAAAGAAAATTTAAGAAGCAATGAGCATCCTAAAGCTGCCAGTG
ATTCTCATTGTGTTCTCTGTGGCATTAAACCATCTGGAAGCTACATCCATTGAAAAACAGGAAT
GGCTAGTTCCGGTTTTGCCAAGAAATATGCTGTTGGAACTTAAAGGAGCAAAGACAGAATCCGA
AATAAGAAAATCCAAAAGTCATCAGATGGAAAAACAGAAATGCAACATGGCCACTTGTGCGACT
CAACACCTGGCAAATTTTTTAGATCGTTCCAGGAACAACCTTGGCACCATTTTCTCACCTACCA
AGGTGGGATCCAACACATATGGCAAGAGGGATACAGTTGAGATTTTAATGAAAGAACCATTGAA
TTACTTACCCCTTTAGAGGTCAACGCACCTCTAAAGTTCTTATTGCTTTATGTATAAATACCCT
AGTGATTTCCTGTATAATTTAACAGTACCTTTTTCATTTCTAAAGTGAATATGTGAATCTGTGT
GTCCCATGTTTGCTGCCAGTACATGTAAACTGTTGTGCTGAGAATTGTTTTAAATTTAATACTA
ATCAAGATCCCTTAATAAAAAGGCAAAGTCTTTACAAATGAAA

hide sequence

RefSeq Acc Id:

XR_002344089

Type:

NON-CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	5	52,046,570 - 52,051,475 (-)	NCBI

Sequence:

show sequence

ATTTGCCTAATACAATTTTTTTTCTACTGTACAATCACTTATGATGGAGCAAATCATATGATTT
TTATATTTCTTTTTAGACTATCAGTAATTTTCACAGAAATACTAAAATTTCAGAACCATTGGTA
ATTAGAACCAGGACTAGAAAACAGTTTGTTTCTTTCTTCCTAAAACCTCTACTAAACAACCTCA
AACTATATTACTAAGCTTTAAAGAAATACATGAAATCAGAGAACTTAAATATTTTACTTGGAGA
ATAACCATCTTTTTTAGATTTACATGTTTTCACTGACTGCTGGAATTTGTTTTAGTTTCTATAT
ATGACCTTAAGTTGTTATAACTTAGAATGTTAACTTAAATATGACTTAAAATACAGGAAGAAAA
AAGAGTAATTTGGAGAAAATAAAAAATAAATCTGTTCCTTCAAAATAATTGTGATGTTTCTCTA
TAAAAATGAAAAAAAGTTGTTAAATAATAGGGAAAAAAAAAACTGCTTGACTACAGTTGTGAAA
TTGTGTTTCTACTTAAATTCTGACAAATGAACTTAAGGATTCAAAAGTAGGCTTTTGATCTCCT
CAGAGTACTTTTTTAAACATTTTACCTTCATCTCTTAATCTACAACTGATTACTGTTGGGACTA
AGGCCAGGGGGCATTTGAATTTAGATAGACTCTTCAAGGTCCATGGCTTCACTCTTTGCATATC
AACACATTTGTTGATACTCCTAATCACTTTACCAATTCCTTATTATAAATTTCTATTTAATCCT
TGAAAATCCACTCTGGTATTCTACAAAGACGGGAAATTTAAATCTCTGCTGTGTGTGACACACC
GTTAACTCCAGCAAGACACCGTATCTGATATGTTAATATTTACAGATTGTTAATGTAATAATGA
CCCATCTGCTTCTGCTGTCATAGGCACTTTCTGTCTAGAGGGATAGAAATTCACGGCAGAGTCT
CTCTGAGCTGCCTGATGTCAGAGCTGGGAAAGGTGTGAAGGGTATACACGAGCTAGATTACTGG
TTAGCAAGTCTGGGGTAAATGTTCCAGTGGATGCAAGCTTGGGATTTTTCATGGAGCTTCTTTG
CTATCAAAGGCATTTTCTGATAGAGCTGACACTGAGACATTAAAAGGTAAGGAATTTTCTGTTT
CTGGGAAAATATTATTGATTTAGCATGAGAACAAATTTGGGATCAAATATAGGGCTTATTTCAA
AGAAATATTAAAGGTATAATGTTCTATAGCACCCATTTTCCAGATTGTTTCGAAAAAGAAATTG
GGTAAATGAAAATTTTGAGCAAATATTTGAAAATTGTTTCAATAGTATTGAGACTGTATCAATA
AAATGATGATCCTGAAAATGATGTTTTAAAAAAAATTTTTGAAGTAGGCTCTAGTTTAATATTC
CATTAATCAGAGCTAAAATAAATGTCCTGATTTCAGTGCTGAATTATTCTTTTCAGAAAATTTA
AGAAGCAATGAGCATCCTAAAGCTGCCAGTGATTCTCATTGTGTTCTCTGTGGCATTAAACCAT
CTGGAAGCTACATCCATTGAAAAACAGGAATGGCTAGTTCCGGTTTTGCCAAGAAATATGCTGT
TGGAACTTAAAGGAGCAAAGACAGAATCCGAAATAAGAAAATCCAAAAGATGGTTCTGGCAAGA
TCCAAAACTTTTGCATCTCCTTCTGGAACTGAAATATATAGAAATAATGAGGGGACAAATTAAA
ATGGTCAAGAAGTTAACTTTAGAAGATCTAGTCAAAAAGCCAATTGTCCTTAGGGGGATTCTTT
CTAAATTGTTCTATATTGTCAAAATATATTTCTATAGTTTTAACTATTCTGTTAATGAAACAGA
ATTATCATAAAAAGTTAAAATAAAAATTCCTCATGAGTTTACTTGCAAGCTGCTCTAAACGTAC
ATTAATACCTCTTGAAAATGTTTTCAATAGGTAGCATGCACACCAGAATTTCTTTTTTAAAAAA
CATTTTGAAAGGTGTCATTTCACTTGAACGGCAATTGTAAGGAAGTCCAAAAATTATGTGGGGT
GAAAATATGTTAGCAGTAATTACAATTTTCAAGTTGAAAGCCTTTAAAACTGTAATTCTCCATT
TATTTAAAAGATTCTTAAGTCCAAATTCATGCACATGTCGTAGGTAATATAAGGAACCTAGTTG
GTTTTGACTGCATATAGTTTGTGCCTACTTGGTTCTGACTGCATGGTTTTGCCGAATTGAACTT
GTACTCTCCTAAAGACCAAGAAGAATAGGTTAACTTCTCATAGAATTACCAGCATCTTATCTGT
TTTCCTTCTGGGTGTTTTTTTGTTGAGGGGTAGGTTTTTGGTGATATGTAAAGATTTCCAAAGC
ACCGACACATAATTAATAATAAGAATCAGGGAAAGATTTTTCTTTTTGTTTCAGGGCTTATCTA
ATTTACAGGATGTTCTTCTCAGAACTGACTGTAATTTTCAGTTGGTTTTCTCCTGGATAAAAAT
AACTTTAAAACCGACATGAAGTTTCTTGTAAGCTAGTAGAACAATTGAATGATGACAGGAAAAT
AAGCAATATTACCTAGTGTTTGTGTCTATATCTTGATCTTTTCTTACATTACATATACTCATTT
GCCAAGTATCTCTACCCAGTATCTTTTTAAGTATGTTTGTTTATTGTGAGGTGAACATTACTTA
GAAATATAACATTGCTTATTAACAAATTACATTTTCATGCTAGTCTCACAATCTCTTACTTTAA
ATTATTAGTAGAAATATTTACAGAACATTCACCAATTTTTTTCTCAGGAAATTGAATTTCTTGA
AACTGATGTGTTTGGTCTTTTTTTTTTAAAGATAGTGGCAGAATTCATTTTTTTAAAAGATTTT
TATTTTTTCTATTATAGTTAATTTATAATGTTCCATCAATTTCTGCTGTATAGCAAAGTGACCC
AGTCATACATATATACATATATTTTTCATAATGCTGTATGAAAAATTTCTGTACAGGACAAGAT
ATGAGAGTATATACCATAAGGTTTCACATGAATTCTTAAAATACTTACTCTTAGCAAAGACACA
GATAATGAAGTACTCCCCATACAAAATAAATACATTGAGATAAAATCTACTGCATTTTGCCTCA
AATTACATATATCCACTGGCATCTGGACGTTGAATGAAGCTTCATACCTCTTGTCCACTTTATA
ATTAACCTAAATTTAACTAATATTTTGGTTCCTGTAGAGCTGAAAATGAAAACATTTCTCTAGA
GTTCCTAATAATCCGCAAAAGGCAATGTTATAATTCTGTATCAATTTCCAGGGCTATTGTGAGA
GCGCACTGAAACAAAAGGTCATACAAACATACGGAATTAACATAAATAAATTAACGCAAATAAA
TTCTGAGATGTTACAATTGAAATGAATTATTTAACCTGGTTATCACTTCTGACTTATCCATAAT
ATTTCTATGCAGTTATTCCGGGTGGCTGCGTAATATGGTGACTATTAATACCATTGACATAAAA
AGCCTTTTGGTTTTAACACCTAACCCAATCCTATCAGTAAAACTGCTGAAAGCATAGGAACCAA
GCAGGGGTATAAGAACATGGTAATCTTCATGTATTTATGCTAAGAGTAATAGAATTCCCACCCT
ACAATAGTCAGAGTACCTGAACAGGAATTTGATTCCCTTGAGAATTTATAATATCTGACATTTC
TCTTAACACTCTTGATTCAATGATCTCCAAGAACTTAACAGAAATTAACATTGGTTCATTCTTG
TGTGAAATGTGTAGGAAGTGAATATCTATTTTTTTAATTCAGCAAGTTCCAGGTTACTTATTAG
TTTACATTCTAAATCCTTTTTTAAAAAAATTGGGAAATAGATTCACAAATATTTTAAAAAATAG
AAGACAAAGATATTTTTAATTATTATTTTCTGGAATATATTCTGAATTTCCAAAGAAAGGATTG
TACTGGGAAATTCAACATTGACTATAATAAAGGGTTTGCTGTATGATTTCCAAGCAAACCAAAA
CACTGGGTTACTGATAGGAAGATGTTTCCTTTAGTTTTCATCAATATGAGATATTTGGGGTCAT
ATAGATAGTTGTATCCAATCCTGAGTCTAAGTTTCTAACCTTTCATATTTCTTCGATGTTCCCA
GTCATCAGATGGAAAAACAGAAATGCAACATGGCCACTTGTGCGACTCAACACCTGGCAAATTT
TTTAGATCGTTCCAGGAACAACCTTGGCACCATTTTCTCACCTACCAAGGTGGGATCCAACACA
TATGGCAAGAGGGATACAGTTGAGATTTTAATGAAAGAACCATTGAATTACTTACCCCTTTAGA
GGTCAACGCACCTCTAAAGTTCTTATTGCTTTATGTATAAATACCCTAGTGATTTCCTGTATAA
TTTAACAGTACCTTTTTCATTTCTAAAGTGAATATGTGAATCTGTGTGTCCCATGTTTGCTGCC
AGTACATGTAAACTGTTGTGCTGAGAATTGTTTTAAATTTAATACTAATCAAGATCCCTTAATA
AAAAGGCAAAGTCTTTACAAATGAAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_003126485	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAB05919	(Get FASTA)	NCBI Sequence Viewer
	ADD13605	(Get FASTA)	NCBI Sequence Viewer
	Q29119	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_003126485 ⟸ XM_003126437
- UniProtKB:	A0A4X1VGM3 (UniProtKB/TrEMBL), A0A480NY05 (UniProtKB/TrEMBL), A0A8D1NSV3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSILKLPVILIVFSVALNHLEATSIEKQEWLVPVLPRNMLLELKGAKTESEIRKSKSHQMEKQK CNMATCATQHLANFLDRSRNNLGTIFSPTKVGSNTYGKRDTVEILMKEPLNYLPL hide sequence

Ensembl Acc Id:

ENSSSCP00000046960 ⟸ ENSSSCT00000059687

Protein Domains

Calcitonin peptide-like

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000000582	Ensembl
Gene3D-CATH	6.10.250.2190	UniProtKB/Swiss-Prot
InterPro	Calcitonin/adrenomedullin	UniProtKB/Swiss-Prot
	Pro-islet_amyloid_polypep	UniProtKB/Swiss-Prot
NCBI Gene	IAPP	ENTREZGENE
Pfam	Calc_CGRP_IAPP	UniProtKB/Swiss-Prot
PRINTS	ISLETAMYLOID	UniProtKB/Swiss-Prot
UniProt	A0A287ASB7_PIG	UniProtKB/TrEMBL
	A0A480NY05	ENTREZGENE, UniProtKB/TrEMBL
	A0A4X1VGM3	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D0XB14_PIG	UniProtKB/TrEMBL
	A0A8D0Z8M8_PIG	UniProtKB/TrEMBL
	A0A8D1NSV3	ENTREZGENE, UniProtKB/TrEMBL
	D3Y4D2_PIG	UniProtKB/TrEMBL
	IAPP_PIG	UniProtKB/Swiss-Prot, ENTREZGENE
VGNC ID	VGNC:89015	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

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Imported Disease Annotations - CTD

Imported Disease Annotations - MGI