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Gene: KEL (Kell metallo-endopeptidase) Sus scrofa

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Symbol:

KEL

Name:

Kell metallo-endopeptidase

RGD ID:

14229154

Description:

ENCODES a protein that exhibits metal ion binding (inferred); metalloendopeptidase activity (inferred); metallopeptidase activity (inferred); INVOLVED IN establishment of localization in cell (ortholog); intracellular calcium ion homeostasis (ortholog); intracellular magnesium ion homeostasis (ortholog); ASSOCIATED WITH hemolytic disease of the fetus (ortholog); Vein of Galen Aneurysm (ortholog); FOUND IN cytosol (inferred); Golgi apparatus (inferred); membrane (inferred); INTERACTS WITH deoxynivalenol

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

kell blood group glycoprotein; Kell blood group, metallo-endopeptidase; Kell metallo-endopeptidase (Kell blood group)

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	18	7,259,144 - 7,279,328 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	18	7,242,378 - 7,279,345 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	18	7,555,045 - 7,594,117 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

hemolytic disease of the fetus (ISO)

Vein of Galen Aneurysm (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

deoxynivalenol (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

establishment of localization in cell (IEA,ISO)

intracellular calcium ion homeostasis (IEA,ISO)

intracellular magnesium ion homeostasis (IEA,ISO)

myelination (IEA,ISO)

negative regulation of potassium ion transmembrane transport (IEA,ISO)

potassium ion transmembrane transport (IEA,ISO)

protein processing (IBA)

proteolysis (IEA)

regulation of axon diameter (IEA,ISO)

regulation of cell size (IEA,ISO)

skeletal muscle fiber development (IEA,ISO)

Cellular Component

cytosol (IEA)

Golgi apparatus (IEA)

membrane (IEA)

nucleoplasm (IEA)

plasma membrane (IBA,IEA)

Molecular Function

metal ion binding (IEA)

metalloendopeptidase activity (IBA,IEA)

metallopeptidase activity (IEA)

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

KEL
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	18	7,259,144 - 7,279,328 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	18	7,242,378 - 7,279,345 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	18	7,555,045 - 7,594,117 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

KEL
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	142,941,114 - 142,962,363 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	7	142,941,114 - 142,962,363 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	7	142,638,201 - 142,659,450 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	142,348,323 - 142,369,625 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	7	142,155,039 - 142,176,340	NCBI
Celera	7	137,475,061 - 137,496,363 (-)	NCBI		Celera
Cytogenetic Map	7	q34	NCBI
HuRef	7	136,976,490 - 136,997,792 (-)	NCBI		HuRef
CHM1_1	7	142,575,086 - 142,596,388 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	7	144,296,525 - 144,394,915 (-)	NCBI		T2T-CHM13v2.0
CRA_TCAGchr7v2	7	142,040,072 - 142,061,375 (-)	NCBI

Kel
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	41,663,263 - 41,681,268 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	41,663,264 - 41,681,273 (-)	Ensembl		GRCm39 Ensembl
GRCm38	6	41,686,329 - 41,704,334 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	41,686,330 - 41,704,339 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	41,636,329 - 41,654,324 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	41,615,942 - 41,633,896 (-)	NCBI		MGSCv36	mm8
Celera	6	41,638,913 - 41,656,912 (-)	NCBI		Celera
Cytogenetic Map	6	B2.1	NCBI
cM Map	6	19.86	NCBI

Kel
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	71,534,882 - 71,552,297 (-)	NCBI		GRCr8
mRatBN7.2	4	70,568,241 - 70,585,666 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	70,568,243 - 70,585,631 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	75,485,787 - 75,502,670 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	71,399,042 - 71,415,925 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	69,807,241 - 69,824,134 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	70,979,504 - 70,996,920 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	70,979,504 - 70,996,395 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	135,766,569 - 135,783,987 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	69,392,846 - 69,409,737 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	4	65,533,172 - 65,550,063 (-)	NCBI		Celera
Cytogenetic Map	4	q23	NCBI

Kel
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955494	668,798 - 688,079 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955494	668,188 - 688,036 (+)	NCBI	ChiLan1.0	ChiLan1.0

LOC100989368
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	6	179,752,428 - 180,141,077 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	7	31,762,687 - 31,860,321 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	7	134,897,567 - 135,237,214 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	7	147,422,965 - 147,444,255 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	147,423,103 - 147,443,895 (-)	Ensembl	panpan1.1		panPan2
PanPan1.1 Ensembl	7	147,389,844 - 147,415,404 (-)	Ensembl	panpan1.1		panPan2

KEL
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	16	6,396,724 - 6,645,221 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	16	6,623,824 - 6,645,094 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	16	7,535,089 - 7,558,835 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	16	6,250,137 - 6,556,234 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	16	6,536,981 - 6,556,219 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	16	6,197,531 - 6,509,648 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	16	6,049,436 - 6,361,088 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	16	6,124,842 - 6,419,811 (+)	NCBI		UU_Cfam_GSD_1.0

Kel
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	12,477,820 - 12,497,394 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936527	406,132 - 427,186 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936527	406,061 - 431,142 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

KEL
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	21	111,819,230 - 111,846,966 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	21	111,819,368 - 111,840,142 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666072	8,542,852 - 8,567,980 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Kel
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624800	11,870,759 - 11,894,190 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624800	11,871,226 - 11,892,584 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in KEL
1274 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	hemolymphoid system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
8	3	12	3	4	11	10	12	3	6	1

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_021078895	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000111	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU928245	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01071767	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSSCT00000017936 ⟹ ENSSSCP00000017455

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	18	7,259,144 - 7,279,328 (+)	Ensembl

Ensembl Acc Id:

ENSSSCT00000073149 ⟹ ENSSSCP00000070096

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	18	7,043,646 - 7,318,395 (+)	Ensembl

RefSeq Acc Id:

XM_021078895 ⟹ XP_020934554

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	18	7,242,378 - 7,279,345 (+)	NCBI

Sequence:

show sequence

CACTGAGGGAGGCCAGGGATCGAACCTGCGTCCTCATGGATGCTAGTCAGATCCATTAACCGCG
GAGCCACGACGGGAACTCTTAAATTGTTCTTCTTTTCTGTAATTTGGCCTGTAGAGTATGTTAT
ATAAATGGAATGATGTAGGTATACAATCTTTGGGGGTTGAATTTTTTCACTCAGAATAATTCTT
TGGAGATTTACCCAGGATGTTGTTTGCATCAATGTTTTGTTGCTTTTTAATACTGAGTAGCACT
GATATGTGTTACTGTAGTTTGTTTAATCATCCAGCCAATGAAGGAAGTCTAAGTTGTTTCCCTT
TTGTCTCTTATAAATAAAACTGCTGCAAATATTTGTGTACAGGTTTTATGTGAACATAAGCTTT
TATTTCTCTGGGATACATGCCCAGGAGTGCAATTGGTGTGTCATATAGTAGTTGCATATTTAAT
TTTTTTTAAAAGATACTGCCAACTGTTTTCTAGAATGGCTATACCATTTTACATTCCCATAAGC
AACATATGAGTGATTCAGATTGTCTGTGTGGCTGGTGGCATTTGGTTGTCACTCTATGCTTTAG
CCACTCTAATATGTAGTAGGGATAGCTCATTGAAATTTTAATTCGCATTTCTCAAGTGGCTAAT
AAGTTTGAACATCTTTCAGTGCTGTGTGTCATCCCTTTATCCTCTTTGGAGAAACACCCTGCAA
TGTCTACTGCCCATTTTCTAAGTGGCTTTTTTTTTAAATTATTATTGAGTTTTGAGAGTTTTAA
CTATATGTGTATATTTTTTCTGATGCTAATCTTTTGTCATATATGTGGTTTGCAAATATTTTTC
CCTAGTCTGTAGTCTGTCTTTTCATCCTCTTAACATGGTTTGCTGAACAGCAAAATTTTTAAAA
AATTTTAATGAAGTCAAATTTATTAATTCTTCATTTTATAGATTGTGCTTTTGGTCTGAGGGGC
GAGGACCAGGAACACCAATGTCTAAGGGCAGGAGAGGATGGGTGTCCTAGCTCAAGCAGACAGA
AAATTTACCCTTCGTCCACCTTTTTGTTCTCTTTGGGCACACAGCAGGTTAGAAGATACCTACA
CACTTTGATGGACCAAACCCCTTATGCTAGCAAGAGAGGGTGTGAGGTTTTCAATCAAGTGCAC
CTTTGGGGCCAGGTGCAGTGGCTGATGGCTTTATGGCTGCAACACCTTTGGTCCATGGATGCAG
CAGAGCGGAACCAGGAAGGAATCTGTGAGCCAGAGAGAAGGGCAGAGAGCCGGCAAGTCCCCTG
GGGAAAGACATTTCCTTCTAGAGTCAGTTCCAGAGGGGGGAGACAAGAGTTGGGGAGAAGCATG
GGGTCTGAGCGAACCAGTGGAGTGGGGACTCCCTGGAGGCTGGAGAGACCTCCAGAAGAGGAGC
TGCCCACTGTCCAGAGCAGACGGTGGGCGAGGGCATTGCGGGCACTAACGACAGTCCTGCTTTT
CAGTCTAATCCTCGGTTCTTCTCTGGTGCTTTGGGCCTACATCCCAGGCTGTCGCCCTCGCCCC
TGTGAGACACTTGTGTGCTGGAATCTCCTGGAACGTTACCTGGCCTCTGAGAACCGAAATGTGG
CCCCTTGCACTGACTTCTTTAGCTTTGCCTGTGGAAACAACAACAGGACCAGGAATTCTTTTCA
GGAACTTGCAGAGGAGAACAAGAACCGGCTTCGGAGGATACTGGAAGCCCCCAGTTCCTGGCAC
CTGGCCCCCGGGAAGGAGAAAGCCTTCCAATTCTACAACTCCTGCATGGACACAGGTGCCATTG
AGGCTGCAGGGGCTGGTCCCCTCAGACAAGTTATTGAGGAGCTCGGAGGCTGGCCAGTCTCTGG
TAATTGGACACCCTTAGACTTTAACCAAACTCTGAGCCTTCTGATGAGTCAATATGGTCACTTC
CCATTCTTCAGAGCCTATTTGCGACCTCTTCCCATCCCTCCCCACACGCCGGTCATCCAGATAG
ACCAGCCAGAGTTTGATGTTCCCCTCAAGCAAAAGCAGGAAATGAAGATCTATGCACAGATCGT
GCGGGAATACCTGACTTACCTGAACCAACTGGGAACTTTGCTGGGAGGAGACCCAAGCCAGGTG
CAACAACACGCCTCCATGTCCATCTCCATCACCTCGCAGCTGTTACAGTTCCTGAGGCCCCAGG
AGCAGCGGCGAGCACAGGGAAAGCTCTTCCAAGTGGTCACAATCGGCCAACTGCAGGAAATGGC
CCCTGTCATCGACTGGTTGTCCTGCTTGCAAGCAATATTCACACCGATGTCCCTGAACCCCTCC
CATTTCATTGCCGTCCACGACCTGGAGTATTTGAAAAACATGTCGCGACTGATTGAAAAGGAGC
TGTCAAAACACAGGGAATTTCTGCAGAGCCACATGATCTTGGGTCTCGTGGGAACCCTCTCTCC
AGCCCTGGACAGTAAATTCCAAGAGGCACGCCGATCGCTGAGCCAGAAACTGGGAGAGCTGACA
GGAGGACCACCCGTGCCCACCCAGCCCCGCTGGATGACGTGCATGGAGGAGATGGAGGCTTTCT
TCGAGCCTACACTGGCAGCCTTGTTTGTCCAGGAGGTCTTCAGCCCAAGCACGCAGAGCGCTGC
CATGGAATTATTCACTGCAATCAAGGATGCCCTCATTGCTCGCCTCCAAAGCCTTCCCTGGATG
GATGAAGAGACCCAGAGAGAGGCCCAGGACAGGATCACCAAACTTCAGGTGAACATGGGGGCCC
CAGAATGGGCCCTGAAGCCAGACCCGGCCACGCAGGAATACGACGATATGCAACTTGGACCCAG
CTTCCTACAATCCTTCCTGAGTGGCATCCGATCCAGCCGAGCTAGAATTATCCGGAGTTTCTTG
CAGCCTTTTCCCAGCCACAGGTGGCACGTGTCCCCCTGGAGGGTCAATGCTTACTATTCAATAT
CTGACCATGTGGTAGTCTTTCCAGCCGGACTCCTCCAACCCCCATTCTTCCACCCTGGCTACCC
CAGAGCCGTGAACTACGGCGCTGCTGGCAGCATCATGGCCCATGAGCTCTTGCACATCTTCTAC
CAGCTGTTACTCCCTGGGGGCTGCCCGGCCTGTGACTCCCATGCCCTACAGGAGGCGCTGCAGT
GCCTGGAGCGCCACTATGCTGGCTTTCCACTACCCAGTGGAATCTCCTTCAATGGCTCCTACTC
ATTCCTGGAGGATGCCGCAGACACAGGGGGGCTGGCCATTGCACTGCAGGCATACAACAAGAGG
CTGTTACGGTACCGTGGGGAGACCACCCTACCCAACCAGGACCTGAGCCCCCAGCAGCTCTTCT
TCCGAAGCTATGCCCAGGTCATGTGTAAGGACCCCAACTTCCAGGATCCTCAGGATACTCACAG
CCCTGCTATCCTCCGAACCCACGGGCCCGTGAGCAACAGCCCAGCCTTCGCCAGACACTTCCAC
TGCCCCCCTGGTGCTCCCATGAACCCCTCCATCCGCTGCCAACTCTGGTAAGCTGGCCAGTTGC
CAAAGAGCCCTCAGTATGGACGTATCATTGTCTCCTTGCCCTGTCCATGAAATCAGGATGGACT
TCTCTCCCGTTCTGCTCCCCAAATAAAACCTGGTCCTTGGCTTCTGCCTGTCTCATAAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_020934554	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000017455
	ENSSSCP00000017455.5
	ENSSSCP00015008698.1
	ENSSSCP00045013965.1
	ENSSSCP00065040577.1

RefSeq Acc Id:

XP_020934554 ⟸ XM_021078895

- UniProtKB:

A0A8D1ZXF0 (UniProtKB/TrEMBL), F1SRT7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MKSNLLILHFIDCAFGLRGEDQEHQCLRAGEDGCPSSSRQKIYPSSTFLFSLGTQQVRRYLHTL
MDQTPYASKRGCEVFNQVHLWGQVQWLMALWLQHLWSMDAAERNQEGICEPERRAESRQVPWGK
TFPSRVSSRGGRQELGRSMGSERTSGVGTPWRLERPPEEELPTVQSRRWARALRALTTVLLFSL
ILGSSLVLWAYIPGCRPRPCETLVCWNLLERYLASENRNVAPCTDFFSFACGNNNRTRNSFQEL
AEENKNRLRRILEAPSSWHLAPGKEKAFQFYNSCMDTGAIEAAGAGPLRQVIEELGGWPVSGNW
TPLDFNQTLSLLMSQYGHFPFFRAYLRPLPIPPHTPVIQIDQPEFDVPLKQKQEMKIYAQIVRE
YLTYLNQLGTLLGGDPSQVQQHASMSISITSQLLQFLRPQEQRRAQGKLFQVVTIGQLQEMAPV
IDWLSCLQAIFTPMSLNPSHFIAVHDLEYLKNMSRLIEKELSKHREFLQSHMILGLVGTLSPAL
DSKFQEARRSLSQKLGELTGGPPVPTQPRWMTCMEEMEAFFEPTLAALFVQEVFSPSTQSAAME
LFTAIKDALIARLQSLPWMDEETQREAQDRITKLQVNMGAPEWALKPDPATQEYDDMQLGPSFL
QSFLSGIRSSRARIIRSFLQPFPSHRWHVSPWRVNAYYSISDHVVVFPAGLLQPPFFHPGYPRA
VNYGAAGSIMAHELLHIFYQLLLPGGCPACDSHALQEALQCLERHYAGFPLPSGISFNGSYSFL
EDAADTGGLAIALQAYNKRLLRYRGETTLPNQDLSPQQLFFRSYAQVMCKDPNFQDPQDTHSPA
ILRTHGPVSNSPAFARHFHCPPGAPMNPSIRCQLW

hide sequence

Ensembl Acc Id:

ENSSSCP00000017455 ⟸ ENSSSCT00000017936

Ensembl Acc Id:

ENSSSCP00000070096 ⟸ ENSSSCT00000073149

Protein Domains

Peptidase M13 C-terminal Peptidase M13 N-terminal

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000016472	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00015016791	UniProtKB/TrEMBL
	ENSSSCG00045011946	UniProtKB/TrEMBL
	ENSSSCG00065067542	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000017936	ENTREZGENE
	ENSSSCT00000017936.6	UniProtKB/TrEMBL
	ENSSSCT00015022278.1	UniProtKB/TrEMBL
	ENSSSCT00045020338.1	UniProtKB/TrEMBL
	ENSSSCT00065092739.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.1380.10	UniProtKB/TrEMBL
	3.40.390.10	UniProtKB/TrEMBL
InterPro	MetalloPept_cat_dom_sf	UniProtKB/TrEMBL
	Peptidase_M13	UniProtKB/TrEMBL
	Peptidase_M13_C	UniProtKB/TrEMBL
	Peptidase_M13_dom_2	UniProtKB/TrEMBL
	Peptidase_M13_N	UniProtKB/TrEMBL
NCBI Gene	KEL	ENTREZGENE
PANTHER	PTHR11733	UniProtKB/TrEMBL
	PTHR11733:SF128	UniProtKB/TrEMBL
Pfam	Peptidase_M13	UniProtKB/TrEMBL
	Peptidase_M13_N	UniProtKB/TrEMBL
PRINTS	NEPRILYSIN	UniProtKB/TrEMBL
PROSITE	NEPRILYSIN	UniProtKB/TrEMBL
Superfamily-SCOP	Metalloproteases ('zincins'), catalytic domain	UniProtKB/TrEMBL
UniProt	A0A8D1ZXF0	ENTREZGENE, UniProtKB/TrEMBL
	F1SRT7	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:110313	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2022-08-22	KEL	Kell metallo-endopeptidase	KEL	Kell metallo-endopeptidase (Kell blood group)	Symbol and/or name change	19259463	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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