HSP90B1 (heat shock protein 90 beta family member 1) - Rat Genome Database

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Gene: HSP90B1 (heat shock protein 90 beta family member 1) Sus scrofa
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Symbol: HSP90B1
Name: heat shock protein 90 beta family member 1
RGD ID: 14211492
Description: ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); ATP-dependent protein folding chaperone (inferred); INVOLVED IN actin rod assembly (ortholog); cellular response to ATP (ortholog); cellular response to manganese ion (ortholog); PARTICIPATES IN codeine and morphine pharmacodynamics pathway; codeine and morphine pharmacokinetics pathway; etoposide pharmacodynamics pathway; ASSOCIATED WITH Diabetic Cardiomyopathies (ortholog); lung adenocarcinoma (ortholog); male infertility due to globozoospermia (ortholog); FOUND IN endoplasmic reticulum chaperone complex (ortholog); smooth endoplasmic reticulum (ortholog); sperm plasma membrane (ortholog); INTERACTS WITH cadmium atom; cadmium dichloride; cobalt dichloride
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 94 kDa glucose-regulated protein; 98 kDa protein kinase; endoplasmin; Gp96; gp96 homolog; GRP-94; GRP94; heat shock protein 90 kDa beta member 1; heat shock protein 90kDa beta (Grp94), member 1; PPK 98; ppk98; TRA1; tumor rejection antigen (gp96) 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl580,511,506 - 80,530,991 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1580,511,513 - 80,531,016 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2584,016,174 - 84,083,931 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:7957217   PMID:9407008   PMID:10101271   PMID:14681463   PMID:15236592   PMID:16731965   PMID:17145712   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
HSP90B1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl580,511,506 - 80,530,991 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1580,511,513 - 80,531,016 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2584,016,174 - 84,083,931 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HSP90B1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812103,930,410 - 103,947,926 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12103,930,107 - 103,953,931 (+)EnsemblGRCh38hg38GRCh38
GRCh3712104,324,188 - 104,341,704 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3612102,848,319 - 102,865,833 (+)NCBINCBI36Build 36hg18NCBI36
Build 3412102,826,655 - 102,844,170NCBI
Celera12103,987,945 - 104,005,473 (+)NCBICelera
Cytogenetic Map12q23.3NCBI
HuRef12101,383,834 - 101,401,444 (+)NCBIHuRef
CHM1_112104,290,083 - 104,307,660 (+)NCBICHM1_1
T2T-CHM13v2.012103,892,110 - 103,909,638 (+)NCBIT2T-CHM13v2.0
Hsp90b1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391086,526,705 - 86,541,308 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1086,526,073 - 86,541,373 (-)EnsemblGRCm39 Ensembl
GRCm381086,690,841 - 86,705,444 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1086,690,209 - 86,705,509 (-)EnsemblGRCm38mm10GRCm38
MGSCv371086,153,586 - 86,168,189 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361086,120,640 - 86,135,243 (-)NCBIMGSCv36mm8
Celera1088,669,594 - 88,684,200 (-)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1043.05NCBI
Hsp90b1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8722,997,962 - 23,012,293 (-)NCBIGRCr8
mRatBN7.2721,110,431 - 21,124,762 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl721,110,457 - 21,124,788 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx723,085,224 - 23,099,540 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0725,247,933 - 25,262,249 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0725,025,008 - 25,039,326 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0727,226,570 - 27,240,533 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl727,226,569 - 27,240,533 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0727,345,730 - 27,359,757 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4723,332,986 - 23,347,525 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1723,353,261 - 23,367,796 (-)NCBI
Celera718,290,242 - 18,304,551 (-)NCBICelera
Cytogenetic Map7q13NCBI
Hsp90b1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540538,629,691 - 38,645,202 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540538,629,691 - 38,645,202 (+)NCBIChiLan1.0ChiLan1.0
HSP90B1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210111,992,374 - 112,010,769 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112111,988,771 - 112,007,166 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012101,506,845 - 101,524,407 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112104,901,997 - 104,919,592 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12104,901,997 - 104,919,329 (+)Ensemblpanpan1.1panPan2
HSP90B1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11542,456,793 - 42,474,122 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1542,456,764 - 42,579,311 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1542,826,278 - 42,843,622 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01543,114,295 - 43,131,887 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1543,114,231 - 43,235,108 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11542,380,743 - 42,398,025 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01542,479,226 - 42,496,568 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01542,750,406 - 42,767,726 (+)NCBIUU_Cfam_GSD_1.0
Hsp90b1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494517,503,494 - 17,517,769 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649210,513,908 - 10,528,285 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649210,513,908 - 10,528,281 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HSP90B1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11199,119,268 - 99,139,988 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1199,119,224 - 99,139,722 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037145,859,568 - 145,877,331 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hsp90b1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247504,737,894 - 4,752,221 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247504,738,563 - 4,752,227 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in HSP90B1
450 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000000926   ⟹   ENSSSCP00000000906
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl580,511,506 - 80,530,991 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000047341   ⟹   ENSSSCP00000042515
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl580,511,506 - 80,530,991 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000101408   ⟹   ENSSSCP00000077198
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl580,511,506 - 80,530,991 (-)Ensembl
RefSeq Acc Id: NM_214103   ⟹   NP_999268
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1580,512,183 - 80,530,862 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021091129   ⟹   XP_020946788
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1580,511,513 - 80,531,016 (-)NCBI
Sequence:
RefSeq Acc Id: XP_020946788   ⟸   XM_021091129
- Peptide Label: isoform X1
- UniProtKB: F1SRK6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_999268   ⟸   NM_214103
- Peptide Label: precursor
- UniProtKB: A0A4X1T658 (UniProtKB/TrEMBL),   A0A8D0KEJ4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000000906   ⟸   ENSSSCT00000000926
Ensembl Acc Id: ENSSSCP00000042515   ⟸   ENSSSCT00000047341
Ensembl Acc Id: ENSSSCP00000077198   ⟸   ENSSSCT00000101408

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000000849 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00030034427 UniProtKB/TrEMBL
  ENSSSCG00040032318 UniProtKB/TrEMBL
  ENSSSCG00045015245 UniProtKB/TrEMBL
  ENSSSCG00055012322 UniProtKB/TrEMBL
  ENSSSCG00060065937 UniProtKB/TrEMBL
  ENSSSCG00065030636 UniProtKB/TrEMBL
  ENSSSCG00070006856 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000000926 ENTREZGENE
  ENSSSCT00000000926.5 UniProtKB/TrEMBL
  ENSSSCT00000047341.3 UniProtKB/TrEMBL
  ENSSSCT00000101408.1 UniProtKB/TrEMBL
  ENSSSCT00030047650.1 UniProtKB/TrEMBL
  ENSSSCT00040043501.1 UniProtKB/TrEMBL
  ENSSSCT00045025856.1 UniProtKB/TrEMBL
  ENSSSCT00055024235.1 UniProtKB/TrEMBL
  ENSSSCT00060090080.1 UniProtKB/TrEMBL
  ENSSSCT00065041453.1 UniProtKB/TrEMBL
  ENSSSCT00070013202.1 UniProtKB/TrEMBL
  ENSSSCT00070013214.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.120.790 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.230.80 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.565.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.11260 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro HATPase_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HATPase_C_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Heat_shock_protein_90_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HSP90_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hsp90_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hsp90_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ribosomal_S5_D2-typ_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:397191 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene HSP90B1 ENTREZGENE
PANTHER ENDOPLASMIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11528 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam HATPase_c_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HSP90 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PIRSF Hsp90 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS HEATSHOCK90 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ER_TARGET UniProtKB/Swiss-Prot
  HSP90 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART HATPase_c UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF110942 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF54211 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF55874 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A287AFA5_PIG UniProtKB/TrEMBL
  A0A4X1T658 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1T7Z2_PIG UniProtKB/TrEMBL
  A0A8D0KEJ4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8W4FFV2_PIG UniProtKB/TrEMBL
  ENPL_PIG UniProtKB/Swiss-Prot
  F1SRK6 ENTREZGENE, UniProtKB/TrEMBL
  Q29092 ENTREZGENE
UniProt Secondary O19070 UniProtKB/Swiss-Prot
  Q29091 UniProtKB/Swiss-Prot
VGNC ID VGNC:103290 ENTREZGENE