OPN4 (opsin 4) - Rat Genome Database

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Gene: OPN4 (opsin 4) Sus scrofa
Analyze
Symbol: OPN4
Name: opsin 4
RGD ID: 14101585
Description: ENCODES a protein that exhibits G protein-coupled photoreceptor activity (ortholog); INVOLVED IN detection of temperature stimulus involved in thermoception (ortholog); phototransduction (ortholog); retina development in camera-type eye (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred); sperm head plasma membrane (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: melanopsin
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1487,647,238 - 87,658,815 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11487,645,563 - 87,660,820 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21494,902,249 - 94,913,351 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:23853360  


Genomics

Comparative Map Data
OPN4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1487,647,238 - 87,658,815 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11487,645,563 - 87,660,820 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21494,902,249 - 94,913,351 (+)NCBISscrofa10.2Sscrofa10.2susScr3
OPN4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381086,654,547 - 86,666,460 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1086,654,518 - 86,666,460 (+)EnsemblGRCh38hg38GRCh38
GRCh371088,414,304 - 88,426,217 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361088,404,294 - 88,416,197 (+)NCBINCBI36Build 36hg18NCBI36
Build 341088,404,377 - 88,416,192NCBI
Celera1082,417,087 - 82,428,990 (+)NCBICelera
Cytogenetic Map10q23.2NCBI
HuRef1082,268,556 - 82,280,460 (+)NCBIHuRef
CHM1_11088,695,970 - 88,707,871 (+)NCBICHM1_1
T2T-CHM13v2.01087,538,707 - 87,550,619 (+)NCBIT2T-CHM13v2.0
Opn4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391434,312,575 - 34,322,099 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1434,312,575 - 34,322,099 (-)EnsemblGRCm39 Ensembl
GRCm381434,590,618 - 34,600,142 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1434,590,618 - 34,600,142 (-)EnsemblGRCm38mm10GRCm38
MGSCv371435,403,804 - 35,413,328 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361433,421,454 - 33,429,234 (-)NCBIMGSCv36mm8
Celera1430,856,294 - 30,865,818 (-)NCBICelera
Cytogenetic Map14BNCBI
cM Map1420.83NCBI
Opn4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8169,926,638 - 9,935,810 (-)NCBIGRCr8
mRatBN7.2169,920,408 - 9,929,580 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl169,920,491 - 10,005,711 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx169,940,099 - 9,949,239 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01611,084,803 - 11,093,943 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0169,935,147 - 9,944,287 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01610,943,353 - 10,966,602 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1610,943,341 - 10,952,549 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0169,268,356 - 9,277,528 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41610,249,756 - 10,258,923 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11610,249,757 - 10,258,921 (-)NCBI
Celera165,287,559 - 5,296,704 (+)NCBICelera
Cytogenetic Map16p15NCBI
Opn4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555105,724,120 - 5,736,135 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555105,723,804 - 5,736,070 (+)NCBIChiLan1.0ChiLan1.0
OPN4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2898,650,558 - 98,659,765 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11098,655,877 - 98,665,084 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01083,082,351 - 83,095,161 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1 Ensembl1086,641,746 - 86,653,143 (+)Ensemblpanpan1.1panPan2
OPN4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1434,350,058 - 34,365,410 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl434,355,128 - 34,365,215 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha434,341,511 - 34,356,871 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0434,709,962 - 34,725,323 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl434,715,036 - 34,725,123 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1434,555,991 - 34,571,338 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0434,725,234 - 34,740,584 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0435,230,251 - 35,245,607 (+)NCBIUU_Cfam_GSD_1.0
Opn4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721344,151,328 - 44,162,304 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936804263,720 - 272,132 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936804261,210 - 272,449 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OPN4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1945,199,897 - 45,212,193 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl945,200,707 - 45,211,636 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660485,312,090 - 5,321,780 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Opn4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624841474,035 - 482,475 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624841472,053 - 483,623 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in OPN4
340 total Variants

Expression

RNA-SEQ Expression

circulatory system
ectoderm
mesenchyme
mesoderm
nervous system
reproductive system
2 2 2 2 2 1

Sequence


Ensembl Acc Id: ENSSSCT00000011340   ⟹   ENSSSCP00000011046
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1487,644,240 - 87,722,245 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000052092   ⟹   ENSSSCP00000058369
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1487,647,238 - 87,658,815 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000060711   ⟹   ENSSSCP00000032418
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1487,647,238 - 87,658,815 (+)Ensembl
RefSeq Acc Id: XM_001925749   ⟹   XP_001925784
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11487,645,563 - 87,660,820 (+)NCBI
Sequence:
RefSeq Acc Id: XP_001925784   ⟸   XM_001925749
- UniProtKB: A0A286ZLT8 (UniProtKB/TrEMBL),   A0A8D1E3Q8 (UniProtKB/TrEMBL),   F1SEN9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000011046   ⟸   ENSSSCT00000011340
Ensembl Acc Id: ENSSSCP00000058369   ⟸   ENSSSCT00000052092
Ensembl Acc Id: ENSSSCP00000032418   ⟸   ENSSSCT00000060711
Protein Domains
G-protein coupled receptors family 1 profile


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000010358 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00025022751 UniProtKB/TrEMBL
  ENSSSCG00035062232 UniProtKB/TrEMBL
  ENSSSCG00040026809 UniProtKB/TrEMBL
  ENSSSCG00045027587 UniProtKB/TrEMBL
  ENSSSCG00050070129 UniProtKB/TrEMBL
  ENSSSCG00055026293 UniProtKB/TrEMBL
  ENSSSCG00060046256 UniProtKB/TrEMBL
  ENSSSCG00065034832 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000052092.3 UniProtKB/TrEMBL
  ENSSSCT00000060711 ENTREZGENE
  ENSSSCT00000060711.3 UniProtKB/TrEMBL
  ENSSSCT00025030911.1 UniProtKB/TrEMBL
  ENSSSCT00035083666.1 UniProtKB/TrEMBL
  ENSSSCT00040036521.1 UniProtKB/TrEMBL
  ENSSSCT00045046983.1 UniProtKB/TrEMBL
  ENSSSCT00050095615.1 UniProtKB/TrEMBL
  ENSSSCT00055052099.1 UniProtKB/TrEMBL
  ENSSSCT00060062818.1 UniProtKB/TrEMBL
  ENSSSCT00065047412.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_opsins UniProtKB/TrEMBL
  GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Opsin UniProtKB/TrEMBL
  Retinal_BS UniProtKB/TrEMBL
KEGG Report ssc:100153077 UniProtKB/TrEMBL
NCBI Gene OPN4 ENTREZGENE
PANTHER MELANOPSIN UniProtKB/TrEMBL
  OPSIN UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/TrEMBL
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OPSIN UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
  OPSIN UniProtKB/TrEMBL
SMART 7TM_GPCR_Srsx UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A286ZLT8 ENTREZGENE
  A0A287BQI1_PIG UniProtKB/TrEMBL
  A0A8D1E3Q8 ENTREZGENE, UniProtKB/TrEMBL
  F1SEN9 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A286ZLT8 UniProtKB/TrEMBL
VGNC ID VGNC:91051 ENTREZGENE