FGF18 (fibroblast growth factor 18) - Rat Genome Database

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Gene: FGF18 (fibroblast growth factor 18) Sus scrofa
Analyze
Symbol: FGF18
Name: fibroblast growth factor 18
RGD ID: 14099704
Description: ENCODES a protein that exhibits growth factor activity (inferred); type 1 fibroblast growth factor receptor binding (inferred); type 2 fibroblast growth factor receptor binding (inferred); INVOLVED IN angiogenesis (ortholog); cell population proliferation (ortholog); chondrocyte development (ortholog); PARTICIPATES IN fibroblast growth factor signaling pathway; ASSOCIATED WITH Diaphragmatic Hernia (ortholog); Dwarfism (ortholog); hydrocephalus (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); INTERACTS WITH chondroitin sulfate; deoxynivalenol; dermatan sulfate
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1652,725,356 - 52,759,791 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11652,724,867 - 52,760,246 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21656,920,916 - 56,956,478 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO)
nucleolus  (IEA)
nucleus  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
FGF18
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1652,725,356 - 52,759,791 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11652,724,867 - 52,760,246 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21656,920,916 - 56,956,478 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FGF18
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385171,419,647 - 171,457,626 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5171,419,647 - 171,457,626 (+)EnsemblGRCh38hg38GRCh38
GRCh375170,846,651 - 170,884,630 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365170,779,272 - 170,816,781 (+)NCBINCBI36Build 36hg18NCBI36
Build 345170,779,271 - 170,816,781NCBI
Celera5166,879,014 - 166,916,982 (+)NCBICelera
Cytogenetic Map5q35.1NCBI
HuRef5165,944,447 - 165,981,862 (+)NCBIHuRef
CHM1_15170,279,191 - 170,317,159 (+)NCBICHM1_1
T2T-CHM13v2.05171,959,977 - 171,997,979 (+)NCBIT2T-CHM13v2.0
Fgf18
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391133,066,970 - 33,097,400 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1133,067,430 - 33,097,400 (-)EnsemblGRCm39 Ensembl
GRCm381133,116,970 - 33,147,400 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1133,117,430 - 33,147,400 (-)EnsemblGRCm38mm10GRCm38
MGSCv371133,017,430 - 33,047,400 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361133,017,430 - 33,047,400 (-)NCBIMGSCv36mm8
Celera1135,529,642 - 35,559,689 (-)NCBICelera
Cytogenetic Map11A4NCBI
cM Map1119.21NCBI
Fgf18
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81018,210,240 - 18,241,929 (-)NCBIGRCr8
mRatBN7.21017,706,011 - 17,737,702 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1017,706,174 - 17,736,818 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1022,455,024 - 22,484,592 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01021,943,626 - 21,973,192 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01017,432,271 - 17,461,845 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01018,047,109 - 18,082,290 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1018,047,109 - 18,063,391 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01017,932,880 - 17,967,318 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1017,348,236 - 17,383,370 (-)NCBICelera
Cytogenetic Map10q12NCBI
Fgf18
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540824,225,459 - 24,260,092 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540824,225,459 - 24,260,057 (+)NCBIChiLan1.0ChiLan1.0
FGF18
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24166,553,461 - 166,591,129 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15164,693,000 - 164,730,916 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05166,765,061 - 166,802,277 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
FGF18
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1440,714,891 - 40,748,892 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl440,715,060 - 40,748,518 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha440,660,286 - 40,697,075 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0441,089,249 - 41,126,052 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl441,091,859 - 41,126,139 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1440,904,218 - 40,941,026 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0441,094,435 - 41,131,275 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0441,604,558 - 41,641,375 (-)NCBIUU_Cfam_GSD_1.0
Fgf18
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721394,954,910 - 94,983,832 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366093,677,237 - 3,706,517 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366093,677,661 - 3,706,511 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FGF18
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12373,584,223 - 73,620,881 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2373,584,766 - 73,620,069 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660345,019,198 - 5,060,806 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fgf18
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473318,599,557 - 18,633,016 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473318,599,186 - 18,633,065 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in FGF18
1064 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
2 1 9 1 3 4 7 9 1 1

Sequence


Ensembl Acc Id: ENSSSCT00000031905   ⟹   ENSSSCP00000028172
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1652,725,356 - 52,760,236 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000073158   ⟹   ENSSSCP00000068781
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1652,725,356 - 52,759,791 (-)Ensembl
RefSeq Acc Id: XM_003134056   ⟹   XP_003134104
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11652,724,867 - 52,760,242 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013990660   ⟹   XP_013846114
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11652,724,867 - 52,760,246 (-)NCBI
Sequence:
RefSeq Acc Id: XP_013846114   ⟸   XM_013990660
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_003134104   ⟸   XM_003134056
- Peptide Label: isoform X2
- UniProtKB: A0A4X1U5Q8 (UniProtKB/TrEMBL),   A0A5G2QUY7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000028172   ⟸   ENSSSCT00000031905
Ensembl Acc Id: ENSSSCP00000068781   ⟸   ENSSSCT00000073158


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000016997 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015073369 UniProtKB/TrEMBL
  ENSSSCG00025017590 UniProtKB/TrEMBL
  ENSSSCG00030032458 UniProtKB/TrEMBL
  ENSSSCG00035067790 UniProtKB/TrEMBL
  ENSSSCG00040069321 UniProtKB/TrEMBL
  ENSSSCG00045006682 UniProtKB/TrEMBL
  ENSSSCG00050001415 UniProtKB/TrEMBL
  ENSSSCG00055007328 UniProtKB/TrEMBL
  ENSSSCG00060012869 UniProtKB/TrEMBL
  ENSSSCG00065010281 UniProtKB/TrEMBL
  ENSSSCG00070015280 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000073158 ENTREZGENE
  ENSSSCT00000073158.1 UniProtKB/TrEMBL
  ENSSSCT00015098587.1 UniProtKB/TrEMBL
  ENSSSCT00025023791.1 UniProtKB/TrEMBL
  ENSSSCT00030044863.1 UniProtKB/TrEMBL
  ENSSSCT00035091470.1 UniProtKB/TrEMBL
  ENSSSCT00040094905.1 UniProtKB/TrEMBL
  ENSSSCT00045011112.1 UniProtKB/TrEMBL
  ENSSSCT00050001700.1 UniProtKB/TrEMBL
  ENSSSCT00050001713.1 UniProtKB/TrEMBL
  ENSSSCT00055014226.1 UniProtKB/TrEMBL
  ENSSSCT00055014253.1 UniProtKB/TrEMBL
  ENSSSCT00060016892.1 UniProtKB/TrEMBL
  ENSSSCT00060016900.1 UniProtKB/TrEMBL
  ENSSSCT00065013652.1 UniProtKB/TrEMBL
  ENSSSCT00065013657.1 UniProtKB/TrEMBL
  ENSSSCT00070030003.1 UniProtKB/TrEMBL
  ENSSSCT00070030005.1 UniProtKB/TrEMBL
Gene3D-CATH 2.80.10.50 UniProtKB/TrEMBL
InterPro Fibroblast_GF_fam UniProtKB/TrEMBL
  IL1/FGF UniProtKB/TrEMBL
KEGG Report ssc:100525013 UniProtKB/TrEMBL
NCBI Gene FGF18 ENTREZGENE
PANTHER PTHR11486 UniProtKB/TrEMBL
  PTHR11486:SF4 UniProtKB/TrEMBL
Pfam FGF UniProtKB/TrEMBL
PRINTS IL1HBGF UniProtKB/TrEMBL
PROSITE HBGF_FGF UniProtKB/TrEMBL
SMART FGF UniProtKB/TrEMBL
Superfamily-SCOP SSF50353 UniProtKB/TrEMBL
UniProt A0A4X1U5Q8 ENTREZGENE, UniProtKB/TrEMBL
  A0A5G2QUY7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1PT54_PIG UniProtKB/TrEMBL
VGNC ID VGNC:88107 ENTREZGENE