BCL2 (BCL2 apoptosis regulator) - Rat Genome Database

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Gene: BCL2 (BCL2 apoptosis regulator) Sus scrofa
Analyze
Symbol: BCL2
Name: BCL2 apoptosis regulator
RGD ID: 14081103
Description: ENCODES a protein that exhibits BH domain binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN actin filament organization (ortholog); animal organ morphogenesis (ortholog); apoptotic mitochondrial changes (ortholog); PARTICIPATES IN ceramide signaling pathway; erythropoietin signaling pathway; interleukin-2 signaling pathway; ASSOCIATED WITH abdominal obesity-metabolic syndrome 1 (ortholog); acute kidney failure (ortholog); Acute Lung Injury (ortholog); FOUND IN cytoplasm (ortholog); endoplasmic reticulum membrane (ortholog); mitochondrial crista (ortholog); INTERACTS WITH (S)-nicotine; 3,3',5,5'-tetrabromobisphenol A; 3-oxalomalic acid
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 3-ketodihydrosphingosine reductase; apoptosis regulator Bcl-2; B-cell CLL/lymphoma 2; KDSR
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1158,337,522 - 158,518,879 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11158,337,403 - 158,518,214 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21175,824,218 - 175,994,403 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
abdominal obesity-metabolic syndrome 1  (ISO)
acute kidney failure  (ISO)
Acute Lung Injury  (ISO)
acute lymphoblastic leukemia  (ISO)
acute myeloid leukemia  (ISO)
adenocarcinoma  (ISO)
adenoma  (ISO)
Adrenal Insufficiency  (ISO)
AIDS-Related Kaposi Sarcoma  (ISO)
alcoholic liver cirrhosis  (ISO)
allergic contact dermatitis  (ISO)
allergic rhinitis  (ISO)
Alzheimer's disease  (ISO)
amyotrophic lateral sclerosis  (ISO)
anti-basement membrane glomerulonephritis  (ISO)
asthma  (ISO)
atherosclerosis  (ISO)
autistic disorder  (ISO)
azoospermia  (ISO)
B-Cell Chronic Lymphocytic Leukemia  (ISO)
bilirubin metabolic disorder  (ISO)
brain glioma  (ISO)
Brain Hypoxia-Ischemia  (ISO)
Brain Injuries  (ISO)
brain ischemia  (ISO)
Breast Neoplasms  (ISO)
Burns  (ISO)
carcinoma  (ISO)
Cerebral Hemorrhage  (ISO)
cervix uteri carcinoma in situ  (ISO)
chromosome 18q deletion syndrome  (ISO)
Chronic Intermittent Hypoxia  (ISO)
clear cell adenocarcinoma  (ISO)
colon adenocarcinoma  (ISO)
colon cancer  (ISO)
Colonic Neoplasms  (ISO)
Colorectal Neoplasms  (ISO)
congestive heart failure  (ISO)
contact dermatitis  (ISO)
dementia  (ISO)
Diabetic Cardiomyopathies  (ISO)
diffuse large B-cell lymphoma  (ISO)
dilated cardiomyopathy  (ISO)
Disease Progression  (ISO)
ductal carcinoma in situ  (ISO)
end stage renal disease  (ISO)
Endometrial Neoplasms  (ISO)
endometriosis  (ISO)
Endotoxemia  (ISO)
Esophageal Neoplasms  (ISO)
esophagus adenocarcinoma  (ISO)
Experimental Allergic Asthma  (ISO)
Experimental Arthritis  (ISO)
Experimental Colitis  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Liver Cirrhosis  (ISO)
Experimental Liver Neoplasms  (ISO)
Experimental Mammary Neoplasms  (ISO)
Familial Prostate Cancer  (ISO)
Fetal Growth Retardation  (ISO)
follicular lymphoma  (ISO)
Gallbladder Neoplasms  (ISO)
gastric ulcer  (ISO)
glaucoma  (ISO)
Head and Neck Neoplasms  (ISO)
Hemorrhagic Shock  (ISO)
hepatocellular carcinoma  (ISO)
Huntington's disease  (ISO)
hypertension  (ISO)
hypertrophic cardiomyopathy  (ISO)
Hypothermia  (ISO)
impotence  (ISO)
intestinal disease  (ISO)
Intestinal Neoplasms  (ISO)
intracranial aneurysm  (ISO)
Kashin-Beck Disease  (ISO)
Kidney Reperfusion Injury  (ISO)
Knee Osteoarthritis  (ISO)
learning disability  (ISO)
leiomyoma  (ISO)
Liver Reperfusion Injury  (ISO)
Lung Injury  (ISO)
Lung Reperfusion Injury  (ISO)
lung small cell carcinoma  (ISO)
Lymphatic Metastasis  (ISO)
male infertility  (ISO)
malignant mesothelioma  (ISO)
melanoma  (ISO)
Memory Disorders  (ISO)
mesenchymal chondrosarcoma  (ISO)
Metaplasia  (ISO)
middle cerebral artery infarction  (ISO)
morphine dependence  (ISO)
Multi-Infarct Dementia  (ISO)
multiple congenital anomalies-hypotonia-seizures syndrome 1  (ISO)
multiple myeloma  (ISO)
myocardial infarction  (ISO)
Myocardial Ischemia  (ISO)
Myocardial Reperfusion Injury  (ISO)
nasopharynx carcinoma  (ISO)
Necrosis  (ISO)
Neoplasm Metastasis  (ISO)
Neoplastic Cell Transformation  (ISO)
Nerve Degeneration  (ISO)
non-Hodgkin lymphoma  (ISO)
obesity  (ISO)
oligomeganephronia  (ISO)
Optic Nerve Injuries  (ISO)
oral mucosa leukoplakia  (ISO)
osteoarthritis  (ISO)
osteochondrodysplasia  (ISO)
osteoporosis  (ISO)
Ovarian Neoplasms  (ISO)
Oxygen-Induced Retinopathy  (ISO)
plasmacytoma  (ISO)
polycystic ovary syndrome  (ISO)
post-traumatic stress disorder  (ISO)
Premature Aging  (ISO)
priapism  (ISO)
prostate cancer  (ISO)
Prostatic Neoplasms  (ISO)
pulmonary hypertension  (ISO)
renal cell carcinoma  (ISO)
Reperfusion Injury  (ISO)
Retina Reperfusion Injury  (ISO)
retinal degeneration  (ISO)
Sarcopenia  (ISO)
Soft Tissue Neoplasms  (ISO)
Spinal Cord Injuries  (ISO)
squamous cell carcinoma  (ISO)
status epilepticus  (ISO)
stomach cancer  (ISO)
Subarachnoid Hemorrhage  (ISO)
synovial sarcoma  (ISO)
T-cell acute lymphoblastic leukemia  (ISO)
Testis Reperfusion Injury  (ISO)
Tongue Neoplasms  (ISO)
tongue squamous cell carcinoma  (ISO)
transient cerebral ischemia  (ISO)
transitional cell carcinoma  (ISO)
Transplant Rejection  (ISO)
type 2 diabetes mellitus  (ISO)
urinary bladder cancer  (ISO)
Ventricular Remodeling  (ISO)
Viral Bronchiolitis  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
3-keto-sphinganine metabolic process  (IEA)
actin filament organization  (IEA,ISO)
animal organ morphogenesis  (IEA,ISO)
apoptotic mitochondrial changes  (IEA,ISO)
apoptotic process  (IEA,ISO)
axon regeneration  (IEA,ISO)
axonogenesis  (IEA,ISO)
B cell apoptotic process  (IEA,ISO)
B cell differentiation  (IEA,ISO)
B cell homeostasis  (IEA,ISO)
B cell lineage commitment  (IEA,ISO)
B cell proliferation  (IEA,ISO)
B cell receptor signaling pathway  (IEA)
behavioral fear response  (IEA,ISO)
branching involved in ureteric bud morphogenesis  (IEA,ISO)
calcium ion transport into cytosol  (IEA,ISO)
CD8-positive, alpha-beta T cell lineage commitment  (IEA,ISO)
cell migration  (IEA,ISO)
cell morphogenesis  (IEA,ISO)
cell population proliferation  (IEA,ISO)
cell-cell adhesion  (IEA,ISO)
cellular response to fluoride  (ISO)
cellular response to glucose starvation  (IEA,ISO)
cellular response to glucose stimulus  (ISO)
cellular response to hydrogen peroxide  (ISO)
cellular response to hypoxia  (IEA,ISO)
cellular response to organic cyclic compound  (ISO)
cerebral cortex development  (ISO)
cochlear nucleus development  (IEA,ISO)
defense response to virus  (IEA)
dendritic cell apoptotic process  (IEA,ISO)
developmental growth  (IEA,ISO)
developmental pigmentation  (IEA,ISO)
digestive tract morphogenesis  (IEA,ISO)
DNA damage response  (IEA)
ear development  (IEA,ISO)
endoplasmic reticulum calcium ion homeostasis  (IEA,ISO)
epithelial cell apoptotic process  (IEA,ISO)
establishment of localization in cell  (IEA,ISO)
extrinsic apoptotic signaling pathway in absence of ligand  (IEA,ISO)
extrinsic apoptotic signaling pathway via death domain receptors  (IEA,ISO)
focal adhesion assembly  (IEA,ISO)
G1/S transition of mitotic cell cycle  (IEA,ISO)
gland morphogenesis  (IEA,ISO)
glial cell apoptotic process  (ISO)
glomerulus development  (IEA,ISO)
hair follicle morphogenesis  (IEA)
hematopoietic stem cell differentiation  (IEA,ISO)
hemopoiesis  (IEA,ISO)
homeostasis of number of cells within a tissue  (IEA,ISO)
immune system development  (IEA,ISO)
intracellular calcium ion homeostasis  (IEA,ISO)
intrinsic apoptotic signaling pathway in response to DNA damage  (IEA,ISO)
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress  (IEA,ISO)
intrinsic apoptotic signaling pathway in response to oxidative stress  (IEA,ISO)
kidney development  (IEA,ISO)
leukocyte homeostasis  (IEA,ISO)
liver regeneration  (ISO)
lymphocyte apoptotic process  (IEA,ISO)
lymphocyte homeostasis  (IEA,ISO)
lymphoid progenitor cell differentiation  (IEA,ISO)
male gonad development  (IEA,ISO)
melanin metabolic process  (IEA,ISO)
melanocyte differentiation  (IEA,ISO)
mesenchymal cell development  (IEA,ISO)
metanephros development  (IEA,ISO)
mitotic cell cycle  (IEA,ISO)
motor neuron apoptotic process  (IEA,ISO)
myeloid cell apoptotic process  (IEA,ISO)
negative regulation of anoikis  (IEA)
negative regulation of apoptotic process  (IEA,ISO)
negative regulation of apoptotic signaling pathway  (IEA,ISO)
negative regulation of autophagy  (IEA)
negative regulation of B cell apoptotic process  (IEA,ISO)
negative regulation of calcium ion transport into cytosol  (IEA,ISO)
negative regulation of cardiac muscle cell apoptotic process  (ISO)
negative regulation of cell growth  (IEA,ISO)
negative regulation of cell migration  (IEA,ISO)
negative regulation of cell population proliferation  (IEA,ISO)
negative regulation of cellular pH reduction  (IEA)
negative regulation of dendritic cell apoptotic process  (IEA,ISO)
negative regulation of epithelial cell apoptotic process  (IEA,ISO)
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand  (IEA,ISO)
negative regulation of G1/S transition of mitotic cell cycle  (IEA,ISO)
negative regulation of intrinsic apoptotic signaling pathway  (IEA)
negative regulation of lymphocyte apoptotic process  (IEA,ISO)
negative regulation of mitotic cell cycle  (IEA,ISO)
negative regulation of motor neuron apoptotic process  (IEA,ISO)
negative regulation of myeloid cell apoptotic process  (IEA,ISO)
negative regulation of neuron apoptotic process  (IEA,ISO)
negative regulation of ossification  (IEA,ISO)
negative regulation of osteoblast proliferation  (IEA,ISO)
negative regulation of reactive oxygen species metabolic process  (IEA)
negative regulation of retinal cell programmed cell death  (IEA,ISO)
negative regulation of T cell apoptotic process  (IEA,ISO)
neuron apoptotic process  (IEA,ISO)
neuron maturation  (IEA,ISO)
oligodendrocyte differentiation  (ISO)
oocyte development  (IEA,ISO)
organ growth  (IEA,ISO)
ossification  (IEA,ISO)
osteoblast proliferation  (IEA,ISO)
ovarian follicle development  (IEA,ISO)
peptidyl-serine phosphorylation  (ISO)
peptidyl-threonine phosphorylation  (ISO)
pigment granule organization  (IEA,ISO)
pigmentation  (IEA)
positive regulation of B cell proliferation  (IEA)
positive regulation of catalytic activity  (ISO)
positive regulation of cell growth  (IEA,ISO)
positive regulation of cell population proliferation  (IEA,ISO)
positive regulation of developmental pigmentation  (IEA,ISO)
positive regulation of melanocyte differentiation  (IEA,ISO)
positive regulation of multicellular organism growth  (IEA,ISO)
positive regulation of neuron maturation  (IEA,ISO)
positive regulation of peptidyl-serine phosphorylation  (ISO)
positive regulation of skeletal muscle fiber development  (IEA,ISO)
positive regulation of smooth muscle cell migration  (IEA,ISO)
post-embryonic development  (IEA,ISO)
protein dephosphorylation  (ISO)
protein polyubiquitination  (IEA,ISO)
reactive oxygen species metabolic process  (IEA,ISO)
regulation of apoptotic process  (IEA,ISO)
regulation of autophagy  (IEA)
regulation of calcium ion transport  (IEA,ISO)
regulation of catalytic activity  (ISO)
regulation of cell cycle  (IEA,ISO)
regulation of cell-matrix adhesion  (IEA,ISO)
regulation of developmental pigmentation  (IEA,ISO)
regulation of gene expression  (IEA,ISO)
regulation of glycoprotein biosynthetic process  (IEA,ISO)
regulation of growth  (IEA,ISO)
regulation of mitochondrial membrane permeability  (IEA)
regulation of mitochondrial membrane potential  (IEA)
regulation of nitrogen utilization  (IEA,ISO)
regulation of programmed cell death  (IEA,ISO)
regulation of protein localization  (IEA,ISO)
regulation of protein stability  (IEA,ISO)
regulation of transmembrane transporter activity  (ISO)
regulation of viral genome replication  (IEA)
release of cytochrome c from mitochondria  (IEA)
renal system process  (IEA,ISO)
response to aluminum ion  (ISO)
response to amyloid-beta  (ISO)
response to anesthetic  (ISO)
response to caffeine  (ISO)
response to cAMP  (ISO)
response to copper ion  (ISO)
response to corticosterone  (ISO)
response to cytokine  (IEA,ISO)
response to electrical stimulus  (ISO)
response to erythropoietin  (ISO)
response to estrogen  (ISO)
response to ethanol  (ISO)
response to folic acid  (ISO)
response to gamma radiation  (IEA,ISO)
response to glucocorticoid  (IEA,ISO)
response to hydrogen peroxide  (IEA,ISO)
response to hypoxia  (ISO)
response to insulin  (ISO)
response to iron ion  (IEA)
response to ischemia  (IEA,ISO)
response to L-ascorbic acid  (ISO)
response to monosaccharide  (ISO)
response to nicotine  (IEA,ISO)
response to nutrient  (ISO)
response to oxidative stress  (IEA,ISO)
response to peptide hormone  (ISO)
response to phenylpropanoid  (ISO)
response to steroid hormone  (IEA,ISO)
response to toxic substance  (IEA,ISO)
response to UV-B  (IEA,ISO)
response to vitamin E  (ISO)
response to xenobiotic stimulus  (IEA,ISO)
retinal cell programmed cell death  (IEA,ISO)
skeletal muscle fiber development  (IEA,ISO)
smooth muscle cell migration  (IEA,ISO)
sphingolipid biosynthetic process  (IEA)
sphingolipid metabolic process  (IEA)
spleen development  (IEA,ISO)
stem cell development  (IEA,ISO)
T cell apoptotic process  (IEA,ISO)
T cell differentiation  (IEA,ISO)
T cell differentiation in thymus  (IEA,ISO)
T cell homeostasis  (IEA,ISO)
T cell lineage commitment  (IEA,ISO)
thymus development  (IEA,ISO)
ureteric bud development  (IEA,ISO)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202   PMID:33107129   PMID:38657363  


Genomics

Comparative Map Data
BCL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1158,337,522 - 158,518,879 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11158,337,403 - 158,518,214 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21175,824,218 - 175,994,403 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BCL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381863,123,346 - 63,320,090 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1863,123,346 - 63,320,128 (-)EnsemblGRCh38hg38GRCh38
GRCh371860,790,579 - 60,987,002 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361858,941,559 - 59,137,593 (-)NCBINCBI36Build 36hg18NCBI36
Build 341858,941,558 - 59,136,910NCBI
Celera1857,509,356 - 57,706,116 (-)NCBICelera
Cytogenetic Map18q21.33NCBI
HuRef1857,487,199 - 57,684,751 (-)NCBIHuRef
CHM1_11860,786,149 - 60,982,536 (-)NCBICHM1_1
T2T-CHM13v2.01863,326,497 - 63,525,122 (-)NCBIT2T-CHM13v2.0
Bcl2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391106,465,906 - 106,642,020 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1106,465,908 - 106,642,004 (-)EnsemblGRCm39 Ensembl
GRCm381106,538,176 - 106,714,290 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1106,538,178 - 106,714,274 (-)EnsemblGRCm38mm10GRCm38
MGSCv371108,434,756 - 108,610,867 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361108,365,740 - 108,541,849 (-)NCBIMGSCv36mm8
Celera1109,386,734 - 109,563,656 (-)NCBICelera
Cytogenetic Map1E2.1NCBI
cM Map149.76NCBI
Bcl2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81323,204,464 - 23,366,900 (-)NCBIGRCr8
mRatBN7.21322,689,783 - 22,853,920 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1322,684,989 - 22,853,743 (-)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl1322,684,989 - 22,853,743 (-)NCBImRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1323,013,354 - 23,175,038 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01324,297,817 - 24,459,509 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01322,983,528 - 23,145,223 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01326,605,426 - 26,769,374 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1326,605,426 - 26,769,374 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01331,758,213 - 31,920,775 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41312,730,736 - 12,905,108 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11312,730,735 - 12,905,108 (-)NCBI
Celera1322,550,362 - 22,711,143 (-)NCBICelera
Cytogenetic Map13p11NCBI
Bcl2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540246,916,266 - 47,084,485 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540246,911,125 - 47,084,214 (-)NCBIChiLan1.0ChiLan1.0
BCL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21780,632,173 - 80,830,186 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11866,324,787 - 66,522,695 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01856,481,212 - 56,679,012 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11859,797,184 - 59,993,298 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1859,802,443 - 59,992,100 (-)Ensemblpanpan1.1panPan2
BCL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1113,733,849 - 13,900,653 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl113,731,406 - 13,900,658 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha114,699,877 - 14,866,689 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0113,595,394 - 13,762,294 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl113,595,394 - 13,762,292 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1113,633,483 - 13,799,972 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0113,562,764 - 13,729,319 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0113,811,587 - 13,978,482 (+)NCBIUU_Cfam_GSD_1.0
Bcl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494426,970,171 - 27,134,608 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364972,210,334 - 2,210,921 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364972,209,136 - 2,373,580 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BCL2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11816,440,560 - 16,643,187 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1816,441,733 - 16,637,895 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660609,049,043 - 9,247,859 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bcl2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247928,859,522 - 9,031,344 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247928,854,345 - 9,032,727 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in BCL2
3629 total Variants

Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSSCT00000031522   ⟹   ENSSSCP00000019781
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1158,288,544 - 158,329,881 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000039219   ⟹   ENSSSCP00000040051
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1158,288,544 - 158,329,881 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000039416   ⟹   ENSSSCP00000045868
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1158,337,522 - 158,518,879 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000068024   ⟹   ENSSSCP00000064617
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1158,288,544 - 158,326,614 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000076201   ⟹   ENSSSCP00000067730
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1158,288,544 - 158,329,881 (+)Ensembl
RefSeq Acc Id: XM_021099593   ⟹   XP_020955252
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11158,337,403 - 158,518,214 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021099599   ⟹   XP_020955258
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11158,337,403 - 158,404,293 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021099602   ⟹   XP_020955261
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11158,337,403 - 158,424,070 (+)NCBI
Sequence:
RefSeq Acc Id: XR_002346028
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11158,337,403 - 158,514,337 (+)NCBI
Sequence:
RefSeq Acc Id: XP_020955252   ⟸   XM_021099593
- Peptide Label: isoform X1
- UniProtKB: A0A4X1TUK1 (UniProtKB/TrEMBL),   A0A287APJ6 (UniProtKB/TrEMBL),   A5A790 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020955261   ⟸   XM_021099602
- Peptide Label: isoform X3
- UniProtKB: A0A4X1TRR9 (UniProtKB/TrEMBL),   A5A790 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020955258   ⟸   XM_021099599
- Peptide Label: isoform X2
- UniProtKB: A5A790 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000040051   ⟸   ENSSSCT00000039219
Ensembl Acc Id: ENSSSCP00000045868   ⟸   ENSSSCT00000039416
Ensembl Acc Id: ENSSSCP00000064617   ⟸   ENSSSCT00000068024
Ensembl Acc Id: ENSSSCP00000019781   ⟸   ENSSSCT00000031522
Ensembl Acc Id: ENSSSCP00000067730   ⟸   ENSSSCT00000076201
Protein Domains
Apoptosis regulator Bcl-2 family BH4   Bcl-2 Bcl-2 homology region 1-3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000025744 Ensembl, UniProtKB/TrEMBL
  ENSSSCG00000062696 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015065616 UniProtKB/TrEMBL
  ENSSSCG00025002747 UniProtKB/TrEMBL
  ENSSSCG00030056042 UniProtKB/TrEMBL
  ENSSSCG00035045354 UniProtKB/TrEMBL
  ENSSSCG00040034881 UniProtKB/TrEMBL
  ENSSSCG00045000822 UniProtKB/TrEMBL
  ENSSSCG00050060210 UniProtKB/TrEMBL
  ENSSSCG00055025587 UniProtKB/TrEMBL
  ENSSSCG00065048620 UniProtKB/TrEMBL
  ENSSSCG00070011763 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000039416 ENTREZGENE
  ENSSSCT00000039416.2 UniProtKB/TrEMBL
  ENSSSCT00000068024.2 UniProtKB/TrEMBL
  ENSSSCT00000076201.1 UniProtKB/TrEMBL
  ENSSSCT00015088712.1 UniProtKB/TrEMBL
  ENSSSCT00025003613.1 UniProtKB/TrEMBL
  ENSSSCT00030078085.1 UniProtKB/TrEMBL
  ENSSSCT00035060255.1 UniProtKB/TrEMBL
  ENSSSCT00040047170.1 UniProtKB/TrEMBL
  ENSSSCT00045001187.1 UniProtKB/TrEMBL
  ENSSSCT00050082050.1 UniProtKB/TrEMBL
  ENSSSCT00055050998.1 UniProtKB/TrEMBL
  ENSSSCT00065066508.1 UniProtKB/TrEMBL
  ENSSSCT00070022932.1 UniProtKB/TrEMBL
  ENSSSCT00070022962.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.437.10 UniProtKB/TrEMBL
  NAD(P)-binding Rossmann-like Domain UniProtKB/TrEMBL
InterPro Apop_reg_Bcl2 UniProtKB/TrEMBL
  Bcl-2_BH1-3 UniProtKB/TrEMBL
  Bcl2-like UniProtKB/TrEMBL
  Bcl2/BclX UniProtKB/TrEMBL
  Bcl2_BH1_motif_CS UniProtKB/TrEMBL
  Bcl2_BH2_motif_CS UniProtKB/TrEMBL
  Bcl2_BH3_motif_CS UniProtKB/TrEMBL
  Bcl2_BH4 UniProtKB/TrEMBL
  Bcl2_BH4_motif_CS UniProtKB/TrEMBL
  Blc2-like_sf UniProtKB/TrEMBL
  Blc2_fam UniProtKB/TrEMBL
  KDSR-like UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/TrEMBL
  Sc_DH/Rdtase_CS UniProtKB/TrEMBL
  SDR_fam UniProtKB/TrEMBL
NCBI Gene BCL2 ENTREZGENE
PANTHER 3-KETODIHYDROSPHINGOSINE REDUCTASE UniProtKB/TrEMBL
  3-KETODIHYDROSPHINGOSINE REDUCTASE UniProtKB/TrEMBL
  PTHR11256 UniProtKB/TrEMBL
  PTHR11256:SF11 UniProtKB/TrEMBL
Pfam adh_short UniProtKB/TrEMBL
  Bcl-2 UniProtKB/TrEMBL
  BH4 UniProtKB/TrEMBL
PRINTS APOPREGBCL2 UniProtKB/TrEMBL
  BCL2FAMILY UniProtKB/TrEMBL
  GDHRDH UniProtKB/TrEMBL
  SDRFAMILY UniProtKB/TrEMBL
PROSITE ADH_SHORT UniProtKB/TrEMBL
  BCL2_FAMILY UniProtKB/TrEMBL
  BH1 UniProtKB/TrEMBL
  BH2 UniProtKB/TrEMBL
  BH3 UniProtKB/TrEMBL
  BH4_1 UniProtKB/TrEMBL
  BH4_2 UniProtKB/TrEMBL
SMART BCL UniProtKB/TrEMBL
  BH4 UniProtKB/TrEMBL
Superfamily-SCOP SSF51735 UniProtKB/TrEMBL
  SSF56854 UniProtKB/TrEMBL
UniProt A0A287APJ6 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1TRR9 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1TUK1 ENTREZGENE, UniProtKB/TrEMBL
  A0A5G2QJG8_PIG UniProtKB/TrEMBL
  A0A5G2QS28_PIG UniProtKB/TrEMBL
  A5A790 ENTREZGENE, UniProtKB/TrEMBL
  A7L816_PIG UniProtKB/TrEMBL
VGNC ID VGNC:111791 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-06-26 BCL2  BCL2 apoptosis regulator  KDSR  3-ketodihydrosphingosine reductase  Symbol and/or name change 19259463 PROVISIONAL
2021-08-02 KDSR  3-ketodihydrosphingosine reductase  BCL2  BCL2 apoptosis regulator  Symbol and/or name change 19259463 PROVISIONAL