AQP6 (aquaporin 6) - Rat Genome Database

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Gene: AQP6 (aquaporin 6) Sus scrofa
Analyze
Symbol: AQP6
Name: aquaporin 6
RGD ID: 14032472
Description: ENCODES a protein that exhibits ammonium channel activity (ortholog); carbon dioxide transmembrane transporter activity (ortholog); monoatomic anion channel activity (ortholog); INVOLVED IN nitrate transmembrane transport (ortholog); PARTICIPATES IN water transport pathway; FOUND IN cytoplasmic vesicle membrane (ortholog); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: aquaporin 6, kidney specific; aquaporin-6
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl515,887,966 - 15,890,805 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1515,888,080 - 15,892,113 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2516,068,162 - 16,071,435 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
AQP6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl515,887,966 - 15,890,805 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1515,888,080 - 15,892,113 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2516,068,162 - 16,071,435 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AQP6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381249,972,947 - 49,977,139 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1249,967,194 - 49,977,139 (+)EnsemblGRCh38hg38GRCh38
GRCh371250,366,730 - 50,370,922 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361248,652,887 - 48,657,189 (+)NCBINCBI36Build 36hg18NCBI36
Build 341248,652,891 - 48,657,189NCBI
Celera1249,162,741 - 49,167,043 (+)NCBICelera
Cytogenetic Map12q13.12NCBI
HuRef1247,398,122 - 47,402,424 (+)NCBIHuRef
CHM1_11250,332,778 - 50,337,080 (+)NCBICHM1_1
T2T-CHM13v2.01249,935,958 - 49,940,150 (+)NCBIT2T-CHM13v2.0
Aqp6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391599,495,891 - 99,503,359 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1599,499,281 - 99,503,358 (+)EnsemblGRCm39 Ensembl
GRCm381599,598,468 - 99,605,478 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1599,601,400 - 99,605,477 (+)EnsemblGRCm38mm10GRCm38
MGSCv371599,431,831 - 99,435,908 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361599,429,434 - 99,433,511 (+)NCBIMGSCv36mm8
Celera15101,756,793 - 101,760,851 (+)NCBICelera
Cytogenetic Map15F1NCBI
cM Map1556.13NCBI
Aqp6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87132,611,069 - 132,614,004 (+)NCBIGRCr8
mRatBN7.27130,732,216 - 130,735,149 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7130,633,579 - 130,735,194 (+)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl7130,633,579 - 130,735,194 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7132,535,805 - 132,538,735 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07134,761,384 - 134,764,315 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07134,673,911 - 134,676,841 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07141,258,585 - 141,261,518 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7141,258,584 - 141,261,735 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X115,763,288 - 115,766,221 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47138,347,266 - 138,350,199 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17138,423,702 - 138,426,636 (+)NCBI
Celera7127,213,574 - 127,216,507 (+)NCBICelera
Cytogenetic Map7q36NCBI
Aqp6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955547567,152 - 571,895 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955547567,152 - 570,880 (+)NCBIChiLan1.0ChiLan1.0
AQP6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21044,172,566 - 44,216,164 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11244,169,328 - 44,212,932 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01238,739,047 - 38,782,659 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11239,672,067 - 39,676,636 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1239,672,067 - 39,676,636 (-)Ensemblpanpan1.1panPan2
AQP6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1274,727,732 - 4,731,828 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl274,727,725 - 4,731,316 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2741,527,817 - 41,531,698 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0274,775,594 - 4,779,476 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl274,776,786 - 4,789,859 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1274,740,579 - 4,744,460 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0274,730,402 - 4,734,285 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02741,922,470 - 41,926,347 (+)NCBIUU_Cfam_GSD_1.0
Aqp6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494565,511,431 - 65,514,075 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365127,650,724 - 7,653,274 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365127,650,755 - 7,653,399 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AQP6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11146,199,907 - 46,207,010 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037199,914,619 - 199,919,218 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Aqp6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248162,316,668 - 2,319,650 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248162,314,660 - 2,319,649 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in AQP6
124 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
5 2 4 5 5 5 4 2 1 1

Sequence


Ensembl Acc Id: ENSSSCT00000000227   ⟹   ENSSSCP00000000224
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl515,888,087 - 15,890,805 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000089729   ⟹   ENSSSCP00000072307
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl515,887,966 - 15,890,802 (+)Ensembl
RefSeq Acc Id: NM_001128467   ⟹   NP_001121939
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1515,888,286 - 15,890,805 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021090894   ⟹   XP_020946553
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1515,888,080 - 15,892,113 (+)NCBI
Sequence:
RefSeq Acc Id: XP_020946553   ⟸   XM_021090894
- Peptide Label: isoform X1
- UniProtKB: A0A5G2R5F1 (UniProtKB/TrEMBL),   A0A8D1RXV8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001121939   ⟸   NM_001128467
- UniProtKB: B2MUK1 (UniProtKB/TrEMBL),   A0A4X1WDR2 (UniProtKB/TrEMBL),   A0A5G2R5F1 (UniProtKB/TrEMBL),   A0A8D1RXV8 (UniProtKB/TrEMBL),   A0A8D1T7R8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000072307   ⟸   ENSSSCT00000089729
Ensembl Acc Id: ENSSSCP00000000224   ⟸   ENSSSCT00000000227


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000000212 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015079975 UniProtKB/TrEMBL
  ENSSSCG00025072829 UniProtKB/TrEMBL
  ENSSSCG00030055083 UniProtKB/TrEMBL
  ENSSSCG00035072348 UniProtKB/TrEMBL
  ENSSSCG00040026125 UniProtKB/TrEMBL
  ENSSSCG00045007233 UniProtKB/TrEMBL
  ENSSSCG00050063509 UniProtKB/TrEMBL
  ENSSSCG00055023966 UniProtKB/TrEMBL
  ENSSSCG00060017298 UniProtKB/TrEMBL
  ENSSSCG00065062259 UniProtKB/TrEMBL
  ENSSSCG00070030455 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000000227 ENTREZGENE
  ENSSSCT00000000227.4 UniProtKB/TrEMBL
  ENSSSCT00000089729.2 UniProtKB/TrEMBL
  ENSSSCT00015108681.1 UniProtKB/TrEMBL
  ENSSSCT00025100216.1 UniProtKB/TrEMBL
  ENSSSCT00025100285.1 UniProtKB/TrEMBL
  ENSSSCT00030076741.1 UniProtKB/TrEMBL
  ENSSSCT00035097900.1 UniProtKB/TrEMBL
  ENSSSCT00040034936.1 UniProtKB/TrEMBL
  ENSSSCT00040034961.1 UniProtKB/TrEMBL
  ENSSSCT00045011992.1 UniProtKB/TrEMBL
  ENSSSCT00045012018.1 UniProtKB/TrEMBL
  ENSSSCT00050086475.1 UniProtKB/TrEMBL
  ENSSSCT00055047219.1 UniProtKB/TrEMBL
  ENSSSCT00055047260.1 UniProtKB/TrEMBL
  ENSSSCT00060023128.1 UniProtKB/TrEMBL
  ENSSSCT00060023132.1 UniProtKB/TrEMBL
  ENSSSCT00065085404.1 UniProtKB/TrEMBL
  ENSSSCT00070061307.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1080.10 UniProtKB/TrEMBL
InterPro Aquaporin-like UniProtKB/TrEMBL
  Aquaporin_6 UniProtKB/TrEMBL
  Aquaporin_transptr UniProtKB/TrEMBL
  MIP UniProtKB/TrEMBL
  MIP_CS UniProtKB/TrEMBL
KEGG Report ssc:100145893 UniProtKB/TrEMBL
NCBI Gene AQP6 ENTREZGENE
PANTHER PTHR19139 UniProtKB/TrEMBL
  PTHR19139:SF113 UniProtKB/TrEMBL
Pfam MIP UniProtKB/TrEMBL
PRINTS AQUAPORIN6 UniProtKB/TrEMBL
  MINTRINSICP UniProtKB/TrEMBL
PROSITE MIP UniProtKB/TrEMBL
Superfamily-SCOP SSF81338 UniProtKB/TrEMBL
UniProt A0A4X1WDR2 ENTREZGENE
  A0A5G2R5F1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1RXV8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1T7R8 ENTREZGENE, UniProtKB/TrEMBL
  B2MUK1 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A4X1WDR2 UniProtKB/TrEMBL
VGNC ID VGNC:85434 ENTREZGENE