PDYN (prodynorphin) - Rat Genome Database

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Gene: PDYN (prodynorphin) Sus scrofa
Analyze
Symbol: PDYN
Name: prodynorphin
RGD ID: 14029897
Description: ENCODES a protein that exhibits opioid peptide activity (inferred); INVOLVED IN response to immobilization stress (ortholog); response to nicotine (ortholog); ASSOCIATED WITH alcohol dependence (ortholog); alcohol use disorder (ortholog); Alcohol Withdrawal Seizures (ortholog); FOUND IN axon terminus (ortholog); dendritic spine (ortholog); dense core granule (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: beta-neoendorphin-dynorphin; preprodynorphin; proenkephalin-B
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1733,505,079 - 33,521,532 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11733,505,075 - 33,521,534 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:6123953   PMID:6689399   PMID:17023126   PMID:18277703   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PDYN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1733,505,079 - 33,521,532 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11733,505,075 - 33,521,534 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
PDYN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38201,978,756 - 1,994,285 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl201,978,757 - 1,994,285 (-)EnsemblGRCh38hg38GRCh38
GRCh37201,959,402 - 1,974,931 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36201,907,402 - 1,922,702 (-)NCBINCBI36Build 36hg18NCBI36
Build 34201,907,402 - 1,922,702NCBI
Celera202,023,375 - 2,038,860 (-)NCBICelera
Cytogenetic Map20p13NCBI
HuRef201,909,347 - 1,924,873 (-)NCBIHuRef
CHM1_1201,959,620 - 1,975,149 (-)NCBICHM1_1
T2T-CHM13v2.0202,008,889 - 2,024,418 (-)NCBIT2T-CHM13v2.0
Pdyn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392129,528,469 - 129,541,858 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2129,528,485 - 129,541,764 (-)EnsemblGRCm39 Ensembl
GRCm382129,686,549 - 129,699,938 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2129,686,565 - 129,699,844 (-)EnsemblGRCm38mm10GRCm38
MGSCv372129,513,737 - 129,515,604 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362129,378,007 - 129,391,274 (-)NCBIMGSCv36mm8
Celera2130,916,433 - 130,918,300 (-)NCBICelera
Cytogenetic Map2F1NCBI
cM Map263.19NCBI
Pdyn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83137,354,161 - 137,366,503 (-)NCBIGRCr8
mRatBN7.23116,900,990 - 116,913,334 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3116,900,992 - 116,913,334 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3120,798,229 - 120,810,577 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03129,393,853 - 129,406,201 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03127,054,324 - 127,066,672 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03122,194,327 - 122,206,671 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3122,194,329 - 122,206,671 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03127,809,688 - 127,822,296 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43117,291,025 - 117,303,367 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13117,196,597 - 117,208,923 (-)NCBI
Celera3115,716,443 - 115,728,785 (-)NCBICelera
Cytogenetic Map3q36NCBI
Pdyn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541513,106,062 - 13,119,515 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541513,106,087 - 13,119,497 (-)NCBIChiLan1.0ChiLan1.0
PDYN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2212,972,785 - 2,988,767 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1202,969,613 - 2,985,594 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0202,092,171 - 2,108,141 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1201,856,850 - 1,872,452 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl201,856,850 - 1,872,452 (-)Ensemblpanpan1.1panPan2
PDYN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12419,043,955 - 19,057,413 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2419,053,870 - 19,056,364 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2418,871,870 - 18,885,766 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02419,500,321 - 19,514,217 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2419,498,268 - 19,514,210 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12419,056,568 - 19,070,465 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02419,167,367 - 19,181,264 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02419,495,948 - 19,509,844 (+)NCBIUU_Cfam_GSD_1.0
Pdyn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640168,127,664 - 168,140,097 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648516,559,217 - 16,571,678 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648516,559,371 - 16,571,461 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PDYN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1254,535,516 - 54,551,085 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl254,535,240 - 54,551,104 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666087951,337 - 967,337 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pdyn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247413,237,942 - 3,253,503 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247413,239,101 - 3,253,507 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PDYN
492 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
mesenchyme
mesoderm
nervous system
reproductive system
4 2 21 3 3 2 21 3

Sequence


Ensembl Acc Id: ENSSSCT00000066335   ⟹   ENSSSCP00000031176
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1733,505,079 - 33,521,532 (+)Ensembl
RefSeq Acc Id: NM_001004040   ⟹   NP_001004040
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11733,516,441 - 33,521,534 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021077316   ⟹   XP_020932975
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11733,505,076 - 33,521,533 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021077317   ⟹   XP_020932976
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11733,505,075 - 33,521,533 (+)NCBI
Sequence:
RefSeq Acc Id: XP_020932976   ⟸   XM_021077317
- Peptide Label: isoform X1
- UniProtKB: A0A4X1SIG2 (UniProtKB/TrEMBL),   A0A286ZHZ6 (UniProtKB/TrEMBL),   A0A8D0RQF3 (UniProtKB/TrEMBL),   A0A8D1K7E0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020932975   ⟸   XM_021077316
- Peptide Label: isoform X1
- UniProtKB: A0A4X1SIG2 (UniProtKB/TrEMBL),   A0A286ZHZ6 (UniProtKB/TrEMBL),   A0A8D0RQF3 (UniProtKB/TrEMBL),   A0A8D1K7E0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001004040   ⟸   NM_001004040
- Peptide Label: preproprotein
- UniProtKB: P01214 (UniProtKB/Swiss-Prot),   A0A8D0JIH8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000031176   ⟸   ENSSSCT00000066335


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000037684 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015077918 UniProtKB/TrEMBL
  ENSSSCG00025034190 UniProtKB/TrEMBL
  ENSSSCG00030031716 UniProtKB/TrEMBL
  ENSSSCG00035030823 UniProtKB/TrEMBL
  ENSSSCG00040027060 UniProtKB/TrEMBL
  ENSSSCG00045035744 UniProtKB/TrEMBL
  ENSSSCG00050041690 UniProtKB/TrEMBL
  ENSSSCG00055010452 UniProtKB/TrEMBL
  ENSSSCG00060002397 UniProtKB/TrEMBL
  ENSSSCG00065050055 UniProtKB/TrEMBL
  ENSSSCG00070001349 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000066335 ENTREZGENE
  ENSSSCT00000066335.3 UniProtKB/TrEMBL
  ENSSSCT00015105402.1 UniProtKB/TrEMBL
  ENSSSCT00025046643.1 UniProtKB/TrEMBL
  ENSSSCT00030043928.1 UniProtKB/TrEMBL
  ENSSSCT00035040808.1 UniProtKB/TrEMBL
  ENSSSCT00040036303.1 UniProtKB/TrEMBL
  ENSSSCT00045061341.1 UniProtKB/TrEMBL
  ENSSSCT00050056581.1 UniProtKB/TrEMBL
  ENSSSCT00055020441.1 UniProtKB/TrEMBL
  ENSSSCT00060002936.1 UniProtKB/TrEMBL
  ENSSSCT00065068548.1 UniProtKB/TrEMBL
  ENSSSCT00070002525.1 UniProtKB/TrEMBL
  ENSSSCT00070002541.1 UniProtKB/TrEMBL
InterPro Opioid_neupept UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Proenkphlin_B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:445529 UniProtKB/Swiss-Prot
NCBI Gene PDYN ENTREZGENE
PANTHER PTHR11438 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11438:SF4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Opiods_neuropep UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS OPIOIDPRCRSR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PENKBPRCRSR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE OPIOIDS_PRECURSOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A286ZHZ6 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1SIG2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0JIH8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0Q5T7_PIG UniProtKB/TrEMBL
  A0A8D0RQF3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0WEG3_PIG UniProtKB/TrEMBL
  A0A8D1K7E0 ENTREZGENE, UniProtKB/TrEMBL
  P01214 ENTREZGENE, UniProtKB/Swiss-Prot
VGNC ID VGNC:96477 ENTREZGENE