VCAM1 (vascular cell adhesion molecule 1) - Rat Genome Database

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Gene: VCAM1 (vascular cell adhesion molecule 1) Sus scrofa
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Symbol: VCAM1
Name: vascular cell adhesion molecule 1
RGD ID: 14007778
Description: ENCODES a protein that exhibits integrin binding (ortholog); INVOLVED IN cardiac neuron differentiation (ortholog); cell adhesion (ortholog); cell chemotaxis (ortholog); PARTICIPATES IN eicosanoid signaling pathway; ASSOCIATED WITH Albuminuria (ortholog); Anaphylaxis (ortholog); anemia (ortholog); FOUND IN apical plasma membrane (ortholog); cell periphery (ortholog); cell surface (ortholog); INTERACTS WITH (-)-epigallocatechin 3-gallate; 1,3-thiazolidine-2,4-dione; 3,3',4,4',5-pentachlorobiphenyl
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: vascular cell adhesion protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4117,496,920 - 117,511,222 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14117,496,914 - 117,511,211 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24129,040,268 - 129,054,581 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Albuminuria  (ISO)
Anaphylaxis  (ISO)
anemia  (ISO)
anti-basement membrane glomerulonephritis  (ISO)
aortic disease  (ISO)
arteriosclerosis  (ISO)
atherosclerosis  (ISO)
cardiovascular system disease  (ISO)
carotid artery disease  (ISO)
carotid stenosis  (ISO)
cholestasis  (ISO)
Chronic Intermittent Hypoxia  (ISO)
chronic kidney disease  (ISO)
colitis  (ISO)
dermatitis  (ISO)
Diabetic Nephropathies  (ISO)
diabetic neuropathy  (ISO)
diabetic retinopathy  (ISO)
Diaphragmatic Hernia  (ISO)
Endotoxemia  (ISO)
essential thrombocythemia  (ISO)
Experimental Autoimmune Encephalomyelitis  (ISO)
Experimental Diabetes Mellitus  (ISO)
familial hyperlipidemia  (ISO)
gastrointestinal system disease  (ISO)
glomerulonephritis  (ISO)
hepatocellular carcinoma  (ISO)
Hypercholesterolemia  (ISO)
hypertension  (ISO)
Insulin Resistance  (ISO)
interstitial cystitis  (ISO)
intrahepatic cholestasis of pregnancy  (ISO)
Kidney Reperfusion Injury  (ISO)
Left Ventricular Hypertrophy  (ISO)
liver cirrhosis  (ISO)
lupus nephritis  (ISO)
Lymphocytic Myocarditis  (ISO)
maple syrup urine disease  (ISO)
Metabolic Syndrome  (ISO)
multiple sclerosis  (ISO)
Myocardial Ischemia  (ISO)
Myocardial Reperfusion Injury  (ISO)
Neoplasm Metastasis  (ISO)
obesity  (ISO)
pancreatic cancer  (ISO)
pancreatitis  (ISO)
periodontitis  (ISO)
Pregnancy in Diabetics  (ISO)
Primary Graft Dysfunction  (ISO)
pulmonary embolism  (ISO)
pulmonary hypertension  (ISO)
Reperfusion Injury  (ISO)
rheumatic myocarditis  (ISO)
sickle cell anemia  (ISO)
Stroke  (ISO)
systemic lupus erythematosus  (ISO)
thromboangiitis obliterans  (ISO)
type 1 diabetes mellitus  (ISO)
type 2 diabetes mellitus  (ISO)
ulcerative colitis  (ISO)
uremia  (ISO)
urticaria  (ISO)
Venous Thrombosis  (ISO)
Vitamin A Deficiency  (ISO)
Vitamin D Deficiency  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:7516159   PMID:8525525   PMID:14681463   PMID:18312487   PMID:19023092   PMID:21471537   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
VCAM1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4117,496,920 - 117,511,222 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14117,496,914 - 117,511,211 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24129,040,268 - 129,054,581 (-)NCBISscrofa10.2Sscrofa10.2susScr3
VCAM1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381100,719,742 - 100,739,045 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1100,719,742 - 100,739,045 (+)EnsemblGRCh38hg38GRCh38
GRCh371101,185,298 - 101,204,601 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361100,957,885 - 100,977,189 (+)NCBINCBI36Build 36hg18NCBI36
Build 341100,897,317 - 100,916,620NCBI
Celera199,446,448 - 99,465,752 (+)NCBICelera
Cytogenetic Map1p21.2NCBI
HuRef199,309,886 - 99,329,291 (+)NCBIHuRef
CHM1_11101,301,307 - 101,320,707 (+)NCBICHM1_1
T2T-CHM13v2.01100,568,139 - 100,587,438 (+)NCBIT2T-CHM13v2.0
Vcam1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393115,903,669 - 115,923,337 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3115,903,598 - 115,923,337 (-)EnsemblGRCm39 Ensembl
GRCm383116,110,020 - 116,129,688 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3116,109,949 - 116,129,688 (-)EnsemblGRCm38mm10GRCm38
MGSCv373115,812,938 - 115,832,606 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363116,102,024 - 116,121,692 (-)NCBIMGSCv36mm8
Celera3122,538,966 - 122,558,635 (-)NCBICelera
Cytogenetic Map3G1NCBI
cM Map350.17NCBI
Vcam1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82206,723,050 - 206,742,783 (-)NCBIGRCr8
mRatBN7.22204,038,120 - 204,057,852 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2204,038,114 - 204,057,958 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2211,702,572 - 211,722,182 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02209,587,221 - 209,606,807 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02204,404,257 - 204,423,843 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02219,071,193 - 219,090,931 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2219,071,193 - 219,097,619 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02237,158,192 - 237,177,779 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42212,277,654 - 212,297,376 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12212,240,407 - 212,260,130 (-)NCBI
Celera2196,537,457 - 196,557,044 (-)NCBICelera
RH 3.4 Map21480.6RGD
Cytogenetic Map2q42NCBI
Vcam1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554355,390,751 - 5,411,691 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554355,390,745 - 5,410,025 (+)NCBIChiLan1.0ChiLan1.0
VCAM1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21126,290,653 - 126,308,353 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11125,448,807 - 125,466,124 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01103,377,815 - 103,395,118 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11102,091,121 - 102,108,494 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1102,091,336 - 102,107,732 (+)Ensemblpanpan1.1panPan2
VCAM1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1649,341,669 - 49,359,841 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl649,342,151 - 49,359,933 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha652,013,558 - 52,031,171 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0649,686,812 - 49,704,968 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl649,686,818 - 49,705,286 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1649,380,130 - 49,397,749 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0649,359,940 - 49,377,559 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0649,789,615 - 49,807,229 (-)NCBIUU_Cfam_GSD_1.0
Vcam1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405058110,980,297 - 110,997,141 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936748785,455 - 803,048 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936748785,491 - 802,791 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
VCAM1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12032,616,425 - 32,635,903 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2032,615,333 - 32,635,862 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603825,428,596 - 25,448,051 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Vcam1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248573,606,431 - 3,627,063 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248573,606,573 - 3,625,991 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in VCAM1
598 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000007515   ⟹   ENSSSCP00000007316
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl4117,496,920 - 117,511,222 (-)Ensembl
RefSeq Acc Id: NM_213891   ⟹   NP_999056
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.14117,496,914 - 117,511,211 (-)NCBI
Sequence:
RefSeq Acc Id: NP_999056   ⟸   NM_213891
- Peptide Label: precursor
- UniProtKB: Q28939 (UniProtKB/TrEMBL),   A0A8D0VDD4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000007316   ⟸   ENSSSCT00000007515
Protein Domains
Ig-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000006862 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015063335 UniProtKB/TrEMBL
  ENSSSCG00025011482 UniProtKB/TrEMBL
  ENSSSCG00030007112 UniProtKB/TrEMBL
  ENSSSCG00035008969 UniProtKB/TrEMBL
  ENSSSCG00040074950 UniProtKB/TrEMBL
  ENSSSCG00045006623 UniProtKB/TrEMBL
  ENSSSCG00050017995 UniProtKB/TrEMBL
  ENSSSCG00055006422 UniProtKB/TrEMBL
  ENSSSCG00060035218 UniProtKB/TrEMBL
  ENSSSCG00065017384 UniProtKB/TrEMBL
  ENSSSCG00070011282 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000007515 ENTREZGENE
  ENSSSCT00000007515.6 UniProtKB/TrEMBL
  ENSSSCT00015084758.1 UniProtKB/TrEMBL
  ENSSSCT00015084997.1 UniProtKB/TrEMBL
  ENSSSCT00025015105.1 UniProtKB/TrEMBL
  ENSSSCT00025015202.1 UniProtKB/TrEMBL
  ENSSSCT00030009553.1 UniProtKB/TrEMBL
  ENSSSCT00035011227.1 UniProtKB/TrEMBL
  ENSSSCT00035011229.1 UniProtKB/TrEMBL
  ENSSSCT00035011231.1 UniProtKB/TrEMBL
  ENSSSCT00040103798.1 UniProtKB/TrEMBL
  ENSSSCT00045011035.1 UniProtKB/TrEMBL
  ENSSSCT00050024446.1 UniProtKB/TrEMBL
  ENSSSCT00055012433.1 UniProtKB/TrEMBL
  ENSSSCT00060047748.1 UniProtKB/TrEMBL
  ENSSSCT00065023106.1 UniProtKB/TrEMBL
  ENSSSCT00070021970.1 UniProtKB/TrEMBL
  ENSSSCT00070021975.1 UniProtKB/TrEMBL
  ENSSSCT00070021982.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro ICAM_VCAM UniProtKB/TrEMBL
  ICAM_VCAM_N UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_C2-set UniProtKB/TrEMBL
  Ig_I-set UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
  VCAM-1 UniProtKB/TrEMBL
KEGG Report ssc:396925 UniProtKB/TrEMBL
NCBI Gene VCAM1 ENTREZGENE
PANTHER INTERCELLULAR ADHESION MOLECULE UniProtKB/TrEMBL
  PTHR13771:SF14 UniProtKB/TrEMBL
Pfam C2-set UniProtKB/TrEMBL
  I-set UniProtKB/TrEMBL
  Ig_3 UniProtKB/TrEMBL
PRINTS ICAMVCAM1 UniProtKB/TrEMBL
  VCAM1 UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
SMART IGc2 UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt A0A4X1TMM2_PIG UniProtKB/TrEMBL
  A0A4X1TMM9_PIG UniProtKB/TrEMBL
  A0A4X1TMN3_PIG UniProtKB/TrEMBL
  A0A8D0R022_PIG UniProtKB/TrEMBL
  A0A8D0VDD4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0YL23_PIG UniProtKB/TrEMBL
  A0A8D0YQ76_PIG UniProtKB/TrEMBL
  A0A8D1KMU7_PIG UniProtKB/TrEMBL
  A0A8D1PQ12_PIG UniProtKB/TrEMBL
  F1S567_PIG UniProtKB/TrEMBL
  Q28939 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:94811 ENTREZGENE