CCK (cholecystokinin) - Rat Genome Database

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Gene: CCK (cholecystokinin) Sus scrofa
Analyze
Symbol: CCK
Name: cholecystokinin
RGD ID: 13993395
Description: ENCODES a protein that exhibits hormone activity (ortholog); neuropeptide hormone activity (ortholog); receptor ligand activity (ortholog); INVOLVED IN apoptotic DNA fragmentation (ortholog); axonogenesis (ortholog); cholecystokinin signaling pathway (ortholog); ASSOCIATED WITH acute pancreatitis (ortholog); alcohol dependence (ortholog); Alcohol Withdrawal Delirium (ortholog); FOUND IN axon (ortholog); axon hillock (ortholog); axon initial segment (ortholog)
Type: protein-coding
RefSeq Status: VALIDATED
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1325,937,645 - 25,945,793 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11325,940,674 - 25,945,879 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21328,610,211 - 28,615,371 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:5410106   PMID:6205394   PMID:8443599   PMID:8661698   PMID:8930082   PMID:10449917   PMID:14681463   PMID:15075451   PMID:15152034   PMID:15374756   PMID:17145712   PMID:17407547  
PMID:22301074   PMID:25627687   PMID:27535680   PMID:30032202   PMID:30121362  


Genomics

Comparative Map Data
CCK
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1325,937,645 - 25,945,793 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11325,940,674 - 25,945,879 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21328,610,211 - 28,615,371 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CCK
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38342,257,826 - 42,266,185 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl342,257,825 - 42,266,185 (-)EnsemblGRCh38hg38GRCh38
GRCh37342,299,318 - 42,307,677 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36342,274,322 - 42,281,399 (-)NCBINCBI36Build 36hg18NCBI36
Build 34342,274,321 - 42,281,399NCBI
Celera342,238,692 - 42,247,029 (-)NCBICelera
Cytogenetic Map3p22.1NCBI
HuRef342,342,652 - 42,351,001 (-)NCBIHuRef
CHM1_1342,250,425 - 42,258,774 (-)NCBICHM1_1
T2T-CHM13v2.0342,275,821 - 42,284,183 (-)NCBIT2T-CHM13v2.0
Cck
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399121,318,890 - 121,324,728 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9121,318,890 - 121,324,760 (-)EnsemblGRCm39 Ensembl
GRCm389121,489,824 - 121,495,694 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9121,489,824 - 121,495,694 (-)EnsemblGRCm38mm10GRCm38
MGSCv379121,398,942 - 121,404,807 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369121,338,523 - 121,344,360 (-)NCBIMGSCv36mm8
Celera9121,960,523 - 121,966,357 (-)NCBICelera
Cytogenetic Map9F4NCBI
cM Map972.43NCBI
Cck
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88130,031,012 - 130,037,702 (-)NCBIGRCr8
mRatBN7.28121,153,499 - 121,160,194 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8121,153,500 - 121,160,084 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8126,751,677 - 126,758,281 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08124,950,740 - 124,957,344 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08122,780,342 - 122,786,944 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08130,120,525 - 130,127,515 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8130,120,523 - 130,127,392 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08129,312,785 - 129,319,582 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48126,492,636 - 126,499,220 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18126,512,372 - 126,518,954 (-)NCBI
Celera8120,288,523 - 120,295,093 (-)NCBICelera
RH 3.4 Map81254.7RGD
RH 3.4 Map81282.1RGD
Cytogenetic Map8q32NCBI
Cck
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542028,438,806 - 28,443,458 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542028,438,806 - 28,443,458 (+)NCBIChiLan1.0ChiLan1.0
CCK
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2242,225,061 - 42,233,431 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1342,229,822 - 42,238,192 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0342,168,012 - 42,176,358 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1342,431,021 - 42,439,396 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl342,431,022 - 42,439,396 (-)Ensemblpanpan1.1panPan2
CCK
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12311,414,254 - 11,419,990 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2311,414,249 - 11,454,198 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2311,451,726 - 11,457,488 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02311,701,990 - 11,707,749 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2311,701,991 - 11,707,673 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12311,504,111 - 11,509,872 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02311,646,349 - 11,652,103 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02311,650,493 - 11,656,260 (-)NCBIUU_Cfam_GSD_1.0
Cck
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118200,424,409 - 200,429,945 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366952,776,831 - 2,782,061 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366952,776,705 - 2,782,280 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CCK
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1223,698,192 - 3,705,443 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl223,698,173 - 3,704,956 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041163,500,609 - 163,507,518 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cck
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473077,309,633 - 77,314,384 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473077,310,080 - 77,314,258 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CCK
151 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
5 4 19 2 4 5 19 1

Sequence


Ensembl Acc Id: ENSSSCT00000012346   ⟹   ENSSSCP00000012023
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1325,937,645 - 25,945,793 (-)Ensembl
RefSeq Acc Id: NM_214237   ⟹   NP_999402
RefSeq Status: VALIDATED
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11325,940,674 - 25,945,793 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005669402   ⟹   XP_005669459
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11325,940,674 - 25,945,871 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021068544   ⟹   XP_020924203
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11325,940,674 - 25,945,879 (-)NCBI
Sequence:
RefSeq Acc Id: XP_020924203   ⟸   XM_021068544
- Peptide Label: isoform X2
- UniProtKB: A0A2C9F3A0 (UniProtKB/TrEMBL),   A0A8D0UFZ8 (UniProtKB/TrEMBL),   A0A8D1A2Z0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005669459   ⟸   XM_005669402
- Peptide Label: isoform X1
- UniProtKB: A0A8D1A2Z0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_999402   ⟸   NM_214237
- Peptide Label: precursor
- UniProtKB: P01356 (UniProtKB/Swiss-Prot),   A0A4X1TLX5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000012023   ⟸   ENSSSCT00000012346
Protein Domains
Gastrin/cholecystokinin peptide hormone


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000011277 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00015046493 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00025004054 UniProtKB/TrEMBL
  ENSSSCG00030014993 UniProtKB/TrEMBL
  ENSSSCG00035045503 UniProtKB/TrEMBL
  ENSSSCG00055002439 UniProtKB/TrEMBL
  ENSSSCG00060014614 UniProtKB/TrEMBL
  ENSSSCG00070010008 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000012346 ENTREZGENE
  ENSSSCT00000012346.4 UniProtKB/TrEMBL
  ENSSSCT00000012346.5 UniProtKB/Swiss-Prot
  ENSSSCT00015062069.1 UniProtKB/TrEMBL
  ENSSSCT00015062271.1 UniProtKB/Swiss-Prot
  ENSSSCT00025005374.1 UniProtKB/TrEMBL
  ENSSSCT00030020716.1 UniProtKB/TrEMBL
  ENSSSCT00035060494.1 UniProtKB/TrEMBL
  ENSSSCT00055004621.1 UniProtKB/TrEMBL
  ENSSSCT00060019376.1 UniProtKB/TrEMBL
  ENSSSCT00070019436.1 UniProtKB/Swiss-Prot
  ENSSSCT00070019446.1 UniProtKB/TrEMBL
  ENSSSCT00070019461.1 UniProtKB/TrEMBL
InterPro CCK-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Gastrin/CCK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Gastrin/cholecystokinin_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:397468 UniProtKB/Swiss-Prot
NCBI Gene CCK ENTREZGENE
PANTHER CHOLECYSTOKININ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10786 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Gastrin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE GASTRIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART GASTRIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A2C9F3A0 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1TLX5 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1TM08_PIG UniProtKB/TrEMBL
  A0A8D0UFZ8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1A2Z0 ENTREZGENE, UniProtKB/TrEMBL
  CCKN_PIG UniProtKB/Swiss-Prot, ENTREZGENE
  Q1W3B6_PIG UniProtKB/TrEMBL
VGNC ID VGNC:86334 ENTREZGENE