GNRH1 (gonadotropin releasing hormone 1) - Rat Genome Database

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Gene: GNRH1 (gonadotropin releasing hormone 1) Sus scrofa
Analyze
Symbol: GNRH1
Name: gonadotropin releasing hormone 1
RGD ID: 13976848
Description: ENCODES a protein that exhibits gonadotropin hormone-releasing hormone activity (ortholog); INVOLVED IN estrous cycle (ortholog); female pregnancy (ortholog); male sex determination (ortholog); ASSOCIATED WITH Adrenal Gland Neoplasms (ortholog); adult respiratory distress syndrome (ortholog); amenorrhea (ortholog); FOUND IN axon terminus (ortholog); cytoplasmic side of rough endoplasmic reticulum membrane (ortholog); dendrite (ortholog); INTERACTS WITH 3',5'-cyclic AMP; cobalt atom; copper atom
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: gonadotropin-releasing hormone associated peptide; LHRH; luteinizing hormone-releasing hormone; progonadoliberin I; progonadoliberin-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl149,442,971 - 9,453,035 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1149,442,971 - 9,447,521 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21410,597,132 - 10,607,824 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:4942726   PMID:4946067   PMID:4946275   PMID:22301074  


Genomics

Comparative Map Data
GNRH1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl149,442,971 - 9,453,035 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1149,442,971 - 9,447,521 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21410,597,132 - 10,607,824 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GNRH1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38825,419,258 - 25,425,040 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl825,419,258 - 25,424,654 (-)EnsemblGRCh38hg38GRCh38
GRCh37825,276,774 - 25,282,556 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36825,332,691 - 25,338,473 (-)NCBINCBI36Build 36hg18NCBI36
Build 34825,332,692 - 25,337,836NCBI
Celera824,237,655 - 24,243,437 (-)NCBICelera
Cytogenetic Map8p21.2NCBI
HuRef823,821,751 - 23,827,534 (-)NCBIHuRef
CHM1_1825,478,220 - 25,484,032 (-)NCBICHM1_1
T2T-CHM13v2.0825,694,484 - 25,700,266 (-)NCBIT2T-CHM13v2.0
Gnrh1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391467,982,717 - 67,986,889 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1467,982,630 - 67,986,888 (+)EnsemblGRCm39 Ensembl
GRCm381467,745,181 - 67,749,440 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1467,745,181 - 67,749,439 (+)EnsemblGRCm38mm10GRCm38
MGSCv371468,363,286 - 68,367,493 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361466,699,676 - 66,702,621 (+)NCBIMGSCv36mm8
Celera1465,502,860 - 65,507,056 (+)NCBICelera
Cytogenetic Map14D1NCBI
cM Map1434.66NCBI
Gnrh1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81546,147,878 - 46,152,086 (+)NCBIGRCr8
mRatBN7.21541,972,482 - 41,976,690 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1541,942,339 - 41,976,690 (+)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl1541,972,905 - 41,973,581 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1543,837,145 - 43,841,353 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01544,987,366 - 44,991,574 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01543,432,699 - 43,436,907 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01544,441,856 - 44,446,064 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1544,441,856 - 44,446,064 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1544,442,555 - 44,442,875 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01547,151,131 - 47,155,339 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41547,303,309 - 47,307,517 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11547,319,088 - 47,323,286 (+)NCBI
Celera1541,636,731 - 41,640,939 (+)NCBICelera
Cytogenetic Map15p12NCBI
Gnrh1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540348,343,597 - 48,346,595 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540348,341,731 - 48,346,595 (-)NCBIChiLan1.0ChiLan1.0
GNRH1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2743,960,415 - 43,967,332 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1819,674,806 - 19,680,584 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0824,700,268 - 24,707,332 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1821,609,407 - 21,616,521 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl821,609,407 - 21,615,936 (-)Ensemblpanpan1.1panPan2
GNRH1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12532,038,631 - 32,043,192 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2532,039,613 - 32,043,028 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2532,623,319 - 32,627,816 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02532,237,978 - 32,242,489 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2532,238,905 - 32,242,478 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12532,193,651 - 32,198,162 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02532,043,144 - 32,047,652 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02532,208,954 - 32,213,456 (+)NCBIUU_Cfam_GSD_1.0
Gnrh1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494310,029,435 - 10,033,174 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367571,282,185 - 1,285,832 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367571,282,185 - 1,285,804 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GNRH1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1823,543,717 - 23,550,728 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl823,542,806 - 23,547,771 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605218,616,776 - 18,623,795 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gnrh1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475820,447,583 - 20,450,968 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475820,447,413 - 20,451,059 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in GNRH1
241 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
10 1 16 1 2 4 3 16 1 1

Sequence


Ensembl Acc Id: ENSSSCT00000010581   ⟹   ENSSSCP00000010305
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl149,442,971 - 9,453,035 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000096357   ⟹   ENSSSCP00000078553
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl149,445,219 - 9,453,035 (-)Ensembl
RefSeq Acc Id: NM_214274   ⟹   NP_999439
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1149,442,971 - 9,447,521 (-)NCBI
Sequence:
RefSeq Acc Id: NP_999439   ⟸   NM_214274
- Peptide Label: precursor
- UniProtKB: P49921 (UniProtKB/Swiss-Prot),   B0ZYW9 (UniProtKB/TrEMBL),   A0A8D0M6Y2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000010305   ⟸   ENSSSCT00000010581
Ensembl Acc Id: ENSSSCP00000078553   ⟸   ENSSSCT00000096357


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000009651 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00015018204 UniProtKB/TrEMBL
  ENSSSCG00025063945 UniProtKB/TrEMBL
  ENSSSCG00030009477 UniProtKB/Swiss-Prot
  ENSSSCG00035009035 UniProtKB/Swiss-Prot
  ENSSSCG00040076253 UniProtKB/Swiss-Prot
  ENSSSCG00045024471 UniProtKB/Swiss-Prot
  ENSSSCG00050060777 UniProtKB/Swiss-Prot
  ENSSSCG00055013900 UniProtKB/TrEMBL
  ENSSSCG00060010330 UniProtKB/TrEMBL
  ENSSSCG00065029275 UniProtKB/Swiss-Prot
  ENSSSCG00070023452 UniProtKB/Swiss-Prot
Ensembl Transcript ENSSSCT00000010581 ENTREZGENE
  ENSSSCT00000010581.3 UniProtKB/Swiss-Prot
  ENSSSCT00000096357.1 UniProtKB/TrEMBL
  ENSSSCT00015024072.1 UniProtKB/TrEMBL
  ENSSSCT00025087634.1 UniProtKB/TrEMBL
  ENSSSCT00030012984.1 UniProtKB/Swiss-Prot
  ENSSSCT00035011319.1 UniProtKB/Swiss-Prot
  ENSSSCT00040106151.1 UniProtKB/Swiss-Prot
  ENSSSCT00045041719.1 UniProtKB/Swiss-Prot
  ENSSSCT00050082815.1 UniProtKB/Swiss-Prot
  ENSSSCT00055027418.1 UniProtKB/TrEMBL
  ENSSSCT00060013409.1 UniProtKB/TrEMBL
  ENSSSCT00065039511.1 UniProtKB/Swiss-Prot
  ENSSSCT00070046735.1 UniProtKB/Swiss-Prot
InterPro GnRH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Gonadoliberin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Gonadoliberin_I_precursor UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:397516 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene GNRH1 ENTREZGENE
PANTHER PROGONADOLIBERIN-1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10522 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam GnRH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS GONADOLIBRNI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE GNRH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8D0M6Y2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8W4FI42_PIG UniProtKB/TrEMBL
  B0ZYW9 ENTREZGENE, UniProtKB/TrEMBL
  GON1_PIG UniProtKB/Swiss-Prot, ENTREZGENE
VGNC ID VGNC:88548 ENTREZGENE