GHRH (growth hormone releasing hormone) - Rat Genome Database

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Gene: GHRH (growth hormone releasing hormone) Sus scrofa
Analyze
Symbol: GHRH
Name: growth hormone releasing hormone
RGD ID: 13905803
Description: ENCODES a protein that exhibits growth hormone-releasing hormone activity (ortholog); INVOLVED IN adenohypophysis development (ortholog); adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); adenylate cyclase-modulating G protein-coupled receptor signaling pathway (ortholog); ASSOCIATED WITH Aicardi-Goutieres Syndrome 5 (ortholog); Alzheimer's disease (ortholog); autoimmune polyendocrine syndrome type 1 (ortholog); FOUND IN axon terminus (ortholog); extracellular space (ortholog); perikaryon (ortholog); INTERACTS WITH copper(II) sulfate
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: GRF; Growth hormone-releasing factor; Growth hormone-releasing hormone; somatoliberin
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1740,387,344 - 40,397,857 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11740,386,725 - 40,398,312 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21745,876,581 - 45,887,302 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
GHRH
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1740,387,344 - 40,397,857 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11740,386,725 - 40,398,312 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21745,876,581 - 45,887,302 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GHRH
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382037,251,086 - 37,261,814 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2037,251,086 - 37,261,819 (-)EnsemblGRCh38hg38GRCh38
GRCh372035,879,489 - 35,890,217 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362035,312,903 - 35,318,706 (-)NCBINCBI36Build 36hg18NCBI36
Build 342035,312,902 - 35,318,706NCBI
Celera2032,586,769 - 32,592,579 (-)NCBICelera
Cytogenetic Map20q11.23NCBI
HuRef2032,615,081 - 32,620,891 (-)NCBIHuRef
CHM1_12035,782,445 - 35,788,255 (-)NCBICHM1_1
T2T-CHM13v2.02038,975,156 - 38,985,884 (-)NCBIT2T-CHM13v2.0
Ghrh
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392157,171,416 - 157,190,645 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2157,171,417 - 157,189,426 (-)EnsemblGRCm39 Ensembl
GRCm382157,329,496 - 157,348,725 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2157,329,497 - 157,347,506 (-)EnsemblGRCm38mm10GRCm38
MGSCv372157,155,232 - 157,172,391 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362157,020,942 - 157,038,038 (-)NCBIMGSCv36mm8
Celera2163,265,842 - 163,283,112 (-)NCBICelera
Cytogenetic Map2H1NCBI
cM Map278.25NCBI
Ghrh
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83166,412,763 - 166,432,519 (-)NCBIGRCr8
mRatBN7.23145,992,762 - 146,012,528 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3145,992,763 - 146,011,889 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3149,818,121 - 149,837,238 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03158,319,491 - 158,338,548 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03156,060,811 - 156,079,879 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03153,449,124 - 153,468,794 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3153,449,125 - 153,468,794 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03158,251,824 - 158,270,812 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43148,027,235 - 148,046,352 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13147,933,144 - 147,952,261 (-)NCBI
Celera3144,698,178 - 144,717,216 (-)NCBICelera
Cytogenetic Map3q42NCBI
Ghrh
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542224,481,246 - 24,490,529 (+)NCBIChiLan1.0ChiLan1.0
GHRH
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22142,978,526 - 42,985,770 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12042,971,567 - 42,978,804 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02033,573,001 - 33,583,699 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12034,687,587 - 34,693,258 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2034,687,587 - 34,693,240 (-)Ensemblpanpan1.1panPan2
GHRH
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12425,893,224 - 25,902,095 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2425,893,225 - 25,897,712 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2425,542,127 - 25,546,302 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02426,590,708 - 26,594,898 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2426,590,708 - 26,594,883 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12425,867,994 - 25,872,168 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02425,973,219 - 25,977,394 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02426,462,493 - 26,466,667 (-)NCBIUU_Cfam_GSD_1.0
Ghrh
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640174,794,985 - 174,803,395 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365613,950,340 - 3,952,405 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365613,946,256 - 3,954,472 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GHRH
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1226,482,734 - 26,493,761 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl226,487,973 - 26,493,499 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605075,362,464 - 75,373,119 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ghrh
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046251466,381 - 13,318 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046251465,484 - 8,763 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in GHRH
391 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
4 1 11 1 1 4 3 11 1 3

Sequence


Ensembl Acc Id: ENSSSCT00000008023   ⟹   ENSSSCP00000007809
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1740,387,344 - 40,397,857 (-)Ensembl
RefSeq Acc Id: NM_001195118   ⟹   NP_001182047
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11740,387,344 - 40,397,857 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005672915   ⟹   XP_005672972
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11740,386,725 - 40,398,312 (-)NCBI
Sequence:
RefSeq Acc Id: XP_005672972   ⟸   XM_005672915
- Peptide Label: isoform X1
- UniProtKB: E0Y439 (UniProtKB/TrEMBL),   A0A4X1TLW2 (UniProtKB/TrEMBL),   F1SEL8 (UniProtKB/TrEMBL),   A0A8D0SKU2 (UniProtKB/TrEMBL),   A0A8D1N6H0 (UniProtKB/TrEMBL),   A0A8D1RGT3 (UniProtKB/TrEMBL),   A0A8D1EPS5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001182047   ⟸   NM_001195118
- Peptide Label: precursor
- UniProtKB: E0Y439 (UniProtKB/TrEMBL),   A0A4X1TLW2 (UniProtKB/TrEMBL),   F1SEL8 (UniProtKB/TrEMBL),   A0A8D0SKU2 (UniProtKB/TrEMBL),   A0A8D1N6H0 (UniProtKB/TrEMBL),   A0A8D1RGT3 (UniProtKB/TrEMBL),   A0A8D1EPS5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000007809   ⟸   ENSSSCT00000008023

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000007332 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015014070 UniProtKB/TrEMBL
  ENSSSCG00025048776 UniProtKB/TrEMBL
  ENSSSCG00030020291 UniProtKB/TrEMBL
  ENSSSCG00035030798 UniProtKB/TrEMBL
  ENSSSCG00040043987 UniProtKB/TrEMBL
  ENSSSCG00045006467 UniProtKB/TrEMBL
  ENSSSCG00050055808 UniProtKB/TrEMBL
  ENSSSCG00055021148 UniProtKB/TrEMBL
  ENSSSCG00060073862 UniProtKB/TrEMBL
  ENSSSCG00065075032 UniProtKB/TrEMBL
  ENSSSCG00070009952 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000008023 ENTREZGENE
  ENSSSCT00000008023.3 UniProtKB/TrEMBL
  ENSSSCT00015018739.1 UniProtKB/TrEMBL
  ENSSSCT00025066416.1 UniProtKB/TrEMBL
  ENSSSCT00030028066.1 UniProtKB/TrEMBL
  ENSSSCT00035040771.1 UniProtKB/TrEMBL
  ENSSSCT00040058968.1 UniProtKB/TrEMBL
  ENSSSCT00045010745.1 UniProtKB/TrEMBL
  ENSSSCT00050076139.1 UniProtKB/TrEMBL
  ENSSSCT00055041572.1 UniProtKB/TrEMBL
  ENSSSCT00060101008.1 UniProtKB/TrEMBL
  ENSSSCT00065103451.1 UniProtKB/TrEMBL
  ENSSSCT00070019340.1 UniProtKB/TrEMBL
InterPro Glucagon_GIP_secretin_VIP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VIP/GHRH-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:100499556 UniProtKB/TrEMBL
NCBI Gene GHRH ENTREZGENE
PANTHER PTHR11213 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SOMATOLIBERIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Hormone_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE GLUCAGON UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART GLUCA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A4X1TLW2 ENTREZGENE
  A0A8D0SKU2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0VWP1_PIG UniProtKB/TrEMBL
  A0A8D1EPS5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1N6H0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1RGT3 ENTREZGENE, UniProtKB/TrEMBL
  E0Y439 ENTREZGENE, UniProtKB/TrEMBL
  F1SEL8 ENTREZGENE
  J7IFE7_PIG UniProtKB/TrEMBL
  J7IJ68_PIG UniProtKB/TrEMBL
  J7IN10_PIG UniProtKB/TrEMBL
  P01287 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary A0A4X1TLW2 UniProtKB/TrEMBL
  F1SEL8 UniProtKB/TrEMBL
VGNC ID VGNC:96322 ENTREZGENE