CCT4 (chaperonin containing TCP1 subunit 4) - Rat Genome Database

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Gene: CCT4 (chaperonin containing TCP1 subunit 4) Sus scrofa
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Symbol: CCT4
Name: chaperonin containing TCP1 subunit 4
RGD ID: 13884715
Description: ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); ATP-dependent protein folding chaperone (inferred); INVOLVED IN binding of sperm to zona pellucida (ortholog); positive regulation of protein localization to Cajal body (ortholog); positive regulation of telomere maintenance via telomerase (ortholog); ASSOCIATED WITH hereditary sensory neuropathy (ortholog); schizophrenia (ortholog); FOUND IN cell body (inferred); centrosome (inferred); chaperonin-containing T-complex (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: T-complex protein 1 subunit delta
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl379,924,507 - 79,946,207 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1379,924,338 - 79,941,926 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2383,760,065 - 83,777,463 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:15679890   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CCT4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl379,924,507 - 79,946,207 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1379,924,338 - 79,941,926 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2383,760,065 - 83,777,463 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CCT4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38261,868,085 - 61,888,671 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl261,868,085 - 61,888,671 (-)EnsemblGRCh38hg38GRCh38
GRCh37262,095,220 - 62,115,806 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36261,948,766 - 61,969,295 (-)NCBINCBI36Build 36hg18NCBI36
Build 34262,006,913 - 62,027,442NCBI
Celera261,940,173 - 61,960,736 (-)NCBICelera
Cytogenetic Map2p15NCBI
HuRef261,835,217 - 61,855,722 (-)NCBIHuRef
CHM1_1262,025,224 - 62,045,751 (-)NCBICHM1_1
T2T-CHM13v2.0261,874,246 - 61,894,829 (-)NCBIT2T-CHM13v2.0
Cct4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391122,940,593 - 22,953,336 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1122,940,519 - 22,953,780 (+)EnsemblGRCm39 Ensembl
GRCm381122,990,593 - 23,003,336 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1122,990,519 - 23,003,780 (+)EnsemblGRCm38mm10GRCm38
MGSCv371122,890,593 - 22,903,336 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361122,890,593 - 22,903,336 (+)NCBIMGSCv36mm8
Celera1125,126,226 - 25,138,969 (+)NCBICelera
Cytogenetic Map11A3.2NCBI
cM Map1114.25NCBI
Cct4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr814101,193,057 - 101,205,935 (+)NCBIGRCr8
mRatBN7.21496,991,853 - 97,004,732 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1496,991,859 - 97,005,267 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx14101,325,100 - 101,337,974 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.014102,567,399 - 102,580,273 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01499,039,002 - 99,051,876 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.014107,767,392 - 107,780,270 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl14107,767,392 - 107,780,270 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.014107,843,411 - 107,856,260 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.414103,675,110 - 103,687,893 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.114103,694,320 - 103,707,104 (+)NCBI
Celera1495,973,133 - 95,985,983 (+)NCBICelera
Cytogenetic Map14q22NCBI
Cct4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542422,088,949 - 22,108,514 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542422,088,949 - 22,108,514 (+)NCBIChiLan1.0ChiLan1.0
CCT4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21264,495,636 - 64,516,010 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A64,499,652 - 64,519,655 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A61,950,477 - 61,970,783 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A63,084,090 - 63,104,530 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A63,084,090 - 63,105,216 (-)Ensemblpanpan1.1panPan2
CCT4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11061,859,148 - 61,874,030 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1061,859,245 - 61,874,389 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1061,748,927 - 61,763,778 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01062,867,889 - 62,882,584 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1062,867,244 - 62,882,587 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11062,551,782 - 62,566,434 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01062,855,534 - 62,870,428 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01063,151,020 - 63,165,931 (-)NCBIUU_Cfam_GSD_1.0
Cct4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629221,330,016 - 21,346,300 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364917,224,692 - 7,241,358 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364917,224,989 - 7,241,348 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CCT4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11445,086,932 - 45,106,922 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1445,086,920 - 45,111,271 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604566,727,959 - 66,748,110 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cct4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462483346,076 - 62,665 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462483346,071 - 62,665 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CCT4
400 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000009172   ⟹   ENSSSCP00000008941
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl379,924,507 - 79,946,207 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000085196   ⟹   ENSSSCP00000063538
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl379,924,507 - 79,946,207 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000096517   ⟹   ENSSSCP00000076653
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl379,924,507 - 79,946,207 (+)Ensembl
RefSeq Acc Id: XM_003125100   ⟹   XP_003125148
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1379,924,338 - 79,941,926 (+)NCBI
Sequence:
RefSeq Acc Id: XP_003125148   ⟸   XM_003125100
- UniProtKB: F1SQN1 (UniProtKB/TrEMBL),   A0A4X1WBL9 (UniProtKB/TrEMBL),   A0A8D0KG77 (UniProtKB/TrEMBL),   A0A8D0WWU0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000008941   ⟸   ENSSSCT00000009172
Ensembl Acc Id: ENSSSCP00000063538   ⟸   ENSSSCT00000085196
Ensembl Acc Id: ENSSSCP00000076653   ⟸   ENSSSCT00000096517


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000008377 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015030858 UniProtKB/TrEMBL
  ENSSSCG00025056023 UniProtKB/TrEMBL
  ENSSSCG00030042887 UniProtKB/TrEMBL
  ENSSSCG00035073761 UniProtKB/TrEMBL
  ENSSSCG00040024228 UniProtKB/TrEMBL
  ENSSSCG00045032237 UniProtKB/TrEMBL
  ENSSSCG00050028939 UniProtKB/TrEMBL
  ENSSSCG00055029851 UniProtKB/TrEMBL
  ENSSSCG00060022139 UniProtKB/TrEMBL
  ENSSSCG00065010740 UniProtKB/TrEMBL
  ENSSSCG00070030207 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000009172 ENTREZGENE
  ENSSSCT00000009172.5 UniProtKB/TrEMBL
  ENSSSCT00000085196.2 UniProtKB/TrEMBL
  ENSSSCT00000096517.1 UniProtKB/TrEMBL
  ENSSSCT00015040877.1 UniProtKB/TrEMBL
  ENSSSCT00025076653.1 UniProtKB/TrEMBL
  ENSSSCT00030059782.1 UniProtKB/TrEMBL
  ENSSSCT00035100005.1 UniProtKB/TrEMBL
  ENSSSCT00040032421.1 UniProtKB/TrEMBL
  ENSSSCT00045055047.1 UniProtKB/TrEMBL
  ENSSSCT00050038894.1 UniProtKB/TrEMBL
  ENSSSCT00055059339.1 UniProtKB/TrEMBL
  ENSSSCT00060030058.1 UniProtKB/TrEMBL
  ENSSSCT00065014278.1 UniProtKB/TrEMBL
  ENSSSCT00065014285.1 UniProtKB/TrEMBL
  ENSSSCT00070060786.1 UniProtKB/TrEMBL
  ENSSSCT00070060787.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.560.10 UniProtKB/TrEMBL
  3.30.260.10 UniProtKB/TrEMBL
  3.50.7.10 UniProtKB/TrEMBL
InterPro Chap_CCT_delta UniProtKB/TrEMBL
  Chaperone_TCP-1 UniProtKB/TrEMBL
  Chaperonin_TCP-1_CS UniProtKB/TrEMBL
  Cpn60/TCP-1 UniProtKB/TrEMBL
  GroEL-like_apical_dom_sf UniProtKB/TrEMBL
  GROEL-like_equatorial_sf UniProtKB/TrEMBL
  TCP-1-like_intermed_sf UniProtKB/TrEMBL
  TCP-1_chaperonin UniProtKB/TrEMBL
  thermosome_alpha UniProtKB/TrEMBL
KEGG Report ssc:100521551 UniProtKB/TrEMBL
NCBI Gene CCT4 ENTREZGENE
PANTHER PTHR11353 UniProtKB/TrEMBL
Pfam Cpn60_TCP1 UniProtKB/TrEMBL
PRINTS TCOMPLEXTCP1 UniProtKB/TrEMBL
PROSITE TCP1_1 UniProtKB/TrEMBL
  TCP1_2 UniProtKB/TrEMBL
  TCP1_3 UniProtKB/TrEMBL
Superfamily-SCOP SSF48592 UniProtKB/TrEMBL
  SSF52029 UniProtKB/TrEMBL
  SSF54849 UniProtKB/TrEMBL
UniProt A0A4X1WBE6_PIG UniProtKB/TrEMBL
  A0A4X1WBL9 ENTREZGENE, UniProtKB/TrEMBL
  A0A5G2QN54_PIG UniProtKB/TrEMBL
  A0A8D0KG77 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0WWU0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8W4FCS4_PIG UniProtKB/TrEMBL
  F1SQN1 ENTREZGENE
UniProt Secondary F1SQN1 UniProtKB/TrEMBL
VGNC ID VGNC:86382 ENTREZGENE