LHB (luteinizing hormone subunit beta) - Rat Genome Database

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Gene: LHB (luteinizing hormone subunit beta) Sus scrofa
Analyze
Symbol: LHB (Ensembl: SAXO3)
Name: luteinizing hormone subunit beta
RGD ID: 13874726
Description: ENCODES a protein that exhibits hormone activity (inferred); INVOLVED IN luteinizing hormone signaling pathway involved in ovarian follicle development (ortholog); PARTICIPATES IN luteinizing hormone signaling pathway; ASSOCIATED WITH alcohol use disorder (ortholog); Bradycardia (ortholog); Cocaine-Related Disorders (ortholog); FOUND IN cytoplasm (ortholog); INTERACTS WITH 17beta-estradiol; androst-4-ene-3,17-dione; cobalt atom
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LH-B; LH-beta subunit; LSH-B; LSH-beta; luteinizing hormone beta polypeptide; luteinizing hormone beta subunit; lutropin beta chain; lutropin subunit beta
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl654,263,576 - 54,271,086 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1654,263,574 - 54,269,286 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2650,063,469 - 50,065,072 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap6q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:1701088   PMID:2744222   PMID:4770795   PMID:7789177   PMID:19212008   PMID:22301074   PMID:30032202   PMID:31905166  


Genomics

Comparative Map Data
LHB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl654,263,576 - 54,271,086 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1654,263,574 - 54,269,286 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2650,063,469 - 50,065,072 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap6q21NCBI
LHB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381949,015,980 - 49,019,498 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1949,015,980 - 49,017,091 (-)EnsemblGRCh38hg38GRCh38
GRCh371949,519,237 - 49,520,348 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361954,211,049 - 54,212,159 (-)NCBINCBI36Build 36hg18NCBI36
Build 341954,211,048 - 54,212,159NCBI
Celera1946,386,444 - 46,387,554 (-)NCBICelera
Cytogenetic Map19q13.33NCBI
HuRef1945,895,957 - 45,897,067 (-)NCBIHuRef
CHM1_11949,521,461 - 49,522,571 (-)NCBICHM1_1
T2T-CHM13v2.01952,010,754 - 52,014,273 (-)NCBIT2T-CHM13v2.0
Lhb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39745,070,370 - 45,071,278 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl745,070,244 - 45,071,321 (+)EnsemblGRCm39 Ensembl
GRCm38745,417,608 - 45,421,855 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl745,418,353 - 45,421,854 (+)EnsemblGRCm38mm10GRCm38
GRCm38.p6 Ensembl745,420,820 - 45,421,897 (+)EnsemblGRCm38mm10GRCm38
MGSCv37752,676,316 - 52,677,224 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36745,288,988 - 45,289,896 (+)NCBIMGSCv36mm8
Celera740,876,980 - 40,877,888 (+)NCBICelera
Cytogenetic Map7B3NCBI
cM Map729.3NCBI
Lhb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81105,037,457 - 105,038,446 (+)NCBIGRCr8
mRatBN7.2195,898,269 - 95,901,973 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl195,898,267 - 95,901,963 (+)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl195,900,984 - 95,901,972 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1101,286,408 - 101,287,397 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01109,759,086 - 109,760,075 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01103,049,485 - 103,050,474 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01101,409,992 - 101,413,725 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1101,410,019 - 101,413,724 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01102,489,421 - 102,493,135 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4195,892,999 - 95,893,988 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1195,971,118 - 95,972,098 (+)NCBI
Celera190,156,575 - 90,157,564 (+)NCBICelera
Cytogenetic Map1q22NCBI
Lhb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555591,656,106 - 1,657,192 (+)NCBIChiLan1.0ChiLan1.0
LOC100992969
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22055,150,366 - 55,159,280 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11957,069,851 - 57,078,655 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01946,053,779 - 46,055,250 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11954,738,139 - 54,739,424 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1954,738,139 - 54,739,424 (+)Ensemblpanpan1.1panPan2
LHB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11107,382,855 - 107,384,029 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
ROS_Cfam_1.01107,907,413 - 107,908,590 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11107,575,256 - 107,576,428 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01107,221,425 - 107,222,599 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01108,057,035 - 108,058,209 (+)NCBIUU_Cfam_GSD_1.0
LHB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1642,247,254 - 42,248,822 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607322,134,416 - 22,135,718 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in LHB
53 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
6 2 21 3 4 6 7 21 1 5 1

Sequence


Ensembl Acc Id: ENSSSCT00000061205   ⟹   ENSSSCP00000035033
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl654,263,576 - 54,271,086 (-)Ensembl
RefSeq Acc Id: NM_214080   ⟹   NP_999245
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1654,263,643 - 54,264,684 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021093514   ⟹   XP_020949173
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1654,263,574 - 54,269,285 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021093516   ⟹   XP_020949175
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1654,264,950 - 54,269,286 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021093517   ⟹   XP_020949176
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1654,263,574 - 54,268,687 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021093518   ⟹   XP_020949177
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1654,263,574 - 54,268,248 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021093519   ⟹   XP_020949178
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1654,263,574 - 54,267,104 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021093520   ⟹   XP_020949179
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1654,264,950 - 54,267,329 (-)NCBI
Sequence:
RefSeq Acc Id: XP_020949173   ⟸   XM_021093514
- Peptide Label: isoform X1
- UniProtKB: A0A5S6H6L9 (UniProtKB/TrEMBL),   A0A4X1VZ56 (UniProtKB/TrEMBL),   A0A8D0I921 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020949176   ⟸   XM_021093517
- Peptide Label: isoform X3
- UniProtKB: P01232 (UniProtKB/Swiss-Prot),   Q7YRL0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_020949177   ⟸   XM_021093518
- Peptide Label: isoform X3
- UniProtKB: P01232 (UniProtKB/Swiss-Prot),   Q7YRL0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_020949178   ⟸   XM_021093519
- Peptide Label: isoform X3
- UniProtKB: P01232 (UniProtKB/Swiss-Prot),   Q7YRL0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_999245   ⟸   NM_214080
- Peptide Label: precursor
- UniProtKB: P01232 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_020949175   ⟸   XM_021093516
- Peptide Label: isoform X2
- UniProtKB: A0A8D1H7K4 (UniProtKB/TrEMBL),   A0A8D0HWK4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020949179   ⟸   XM_021093520
- Peptide Label: isoform X4
- Sequence:
Ensembl Acc Id: ENSSSCP00000035033   ⟸   ENSSSCT00000061205

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000044760 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015016010 UniProtKB/TrEMBL
  ENSSSCG00015016126 UniProtKB/Swiss-Prot
  ENSSSCG00025020194 UniProtKB/TrEMBL
  ENSSSCG00030065076 UniProtKB/TrEMBL
  ENSSSCG00035039384 UniProtKB/TrEMBL
  ENSSSCG00040014499 UniProtKB/TrEMBL
  ENSSSCG00040014539 UniProtKB/Swiss-Prot
  ENSSSCG00045012733 UniProtKB/TrEMBL
  ENSSSCG00045012778 UniProtKB/Swiss-Prot
  ENSSSCG00055006858 UniProtKB/TrEMBL
  ENSSSCG00055006892 UniProtKB/Swiss-Prot
  ENSSSCG00060078070 UniProtKB/TrEMBL
  ENSSSCG00060078080 UniProtKB/Swiss-Prot
  ENSSSCG00065054153 UniProtKB/TrEMBL
  ENSSSCG00065054246 UniProtKB/Swiss-Prot
  ENSSSCG00070027711 UniProtKB/TrEMBL
  ENSSSCG00070027728 UniProtKB/Swiss-Prot
Ensembl Transcript ENSSSCT00000061205 ENTREZGENE
  ENSSSCT00000061205.3 UniProtKB/TrEMBL
  ENSSSCT00015021216.1 UniProtKB/TrEMBL
  ENSSSCT00015021278.1 UniProtKB/TrEMBL
  ENSSSCT00015021328.1 UniProtKB/TrEMBL
  ENSSSCT00015021366.1 UniProtKB/Swiss-Prot
  ENSSSCT00025027412.1 UniProtKB/TrEMBL
  ENSSSCT00025027425.1 UniProtKB/TrEMBL
  ENSSSCT00030090937.1 UniProtKB/TrEMBL
  ENSSSCT00030090952.1 UniProtKB/TrEMBL
  ENSSSCT00035052318.1 UniProtKB/TrEMBL
  ENSSSCT00035052320.1 UniProtKB/TrEMBL
  ENSSSCT00040019398.1 UniProtKB/TrEMBL
  ENSSSCT00040019439.1 UniProtKB/TrEMBL
  ENSSSCT00040019465.1 UniProtKB/Swiss-Prot
  ENSSSCT00045021680.1 UniProtKB/TrEMBL
  ENSSSCT00045021710.1 UniProtKB/TrEMBL
  ENSSSCT00045021755.1 UniProtKB/Swiss-Prot
  ENSSSCT00055013269.1 UniProtKB/TrEMBL
  ENSSSCT00055013292.1 UniProtKB/TrEMBL
  ENSSSCT00055013332.1 UniProtKB/Swiss-Prot
  ENSSSCT00060107650.1 UniProtKB/TrEMBL
  ENSSSCT00060107662.1 UniProtKB/TrEMBL
  ENSSSCT00060107671.1 UniProtKB/Swiss-Prot
  ENSSSCT00065074188.1 UniProtKB/TrEMBL
  ENSSSCT00065074197.1 UniProtKB/TrEMBL
  ENSSSCT00065074311.1 UniProtKB/Swiss-Prot
  ENSSSCT00070055580.1 UniProtKB/TrEMBL
  ENSSSCT00070055582.1 UniProtKB/TrEMBL
  ENSSSCT00070055627.1 UniProtKB/Swiss-Prot
Gene3D-CATH 2.10.90.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Axonemal_MT_stabilizer UniProtKB/TrEMBL
  Cystine-knot_cytokine UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glyco_hormone_CN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Gonadotropin_bsu UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Gonadotropin_bsu_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:397153 UniProtKB/Swiss-Prot
NCBI Gene LHB ENTREZGENE
PANTHER HCG1796489 UniProtKB/TrEMBL
  HCG1796489 UniProtKB/TrEMBL
  LUTROPIN SUBUNIT BETA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11515 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Cys_knot UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE GLYCO_HORMONE_BETA_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GLYCO_HORMONE_BETA_2 UniProtKB/Swiss-Prot
SMART GHB UniProtKB/Swiss-Prot
Superfamily-SCOP SSF57501 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A4X1VU24_PIG UniProtKB/TrEMBL
  A0A4X1VZ56 ENTREZGENE, UniProtKB/TrEMBL
  A0A5S6H6L9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0HWK4 ENTREZGENE
  A0A8D0I921 ENTREZGENE
  A0A8D1H7K4 ENTREZGENE, UniProtKB/TrEMBL
  LSHB_PIG UniProtKB/Swiss-Prot, ENTREZGENE
  Q6LC93_PIG UniProtKB/TrEMBL
  Q7YRL0 ENTREZGENE
UniProt Secondary Q7YRL0 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-07-30 LHB  luteinizing hormone subunit beta  LHB  luteinizing hormone beta polypeptide  Symbol and/or name change 5135510 APPROVED