HSP90AB1 (heat shock protein 90 alpha family class B member 1) - Rat Genome Database

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Gene: HSP90AB1 (heat shock protein 90 alpha family class B member 1) Sus scrofa
Analyze
Symbol: HSP90AB1
Name: heat shock protein 90 alpha family class B member 1
RGD ID: 13862011
Description: ENCODES a protein that exhibits ATP binding (ortholog); CTP binding (ortholog); dATP binding (ortholog); INVOLVED IN cellular response to interleukin-4 (ortholog); cellular response to organic cyclic compound (ortholog); negative regulation of apoptotic process (ortholog); PARTICIPATES IN aldosterone signaling pathway; androgen signaling pathway; cortisol signaling pathway; ASSOCIATED WITH Female Infertility (ortholog); human immunodeficiency virus infectious disease (ortholog); intrahepatic cholangiocarcinoma (ortholog); FOUND IN apical plasma membrane (ortholog); basolateral plasma membrane (ortholog); brush border membrane (ortholog)
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: heat shock 90kD protein 1, beta; heat shock protein HSP 90-beta; HSPCB
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl739,244,458 - 39,250,481 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1739,237,299 - 39,250,479 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2745,106,779 - 45,119,936 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:17407547   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
HSP90AB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl739,244,458 - 39,250,481 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1739,237,299 - 39,250,479 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2745,106,779 - 45,119,936 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HSP90AB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38644,246,194 - 44,253,883 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl644,246,166 - 44,253,888 (+)EnsemblGRCh38hg38GRCh38
GRCh37644,213,931 - 44,221,620 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36644,322,827 - 44,329,592 (+)NCBINCBI36Build 36hg18NCBI36
Build 34644,322,826 - 44,329,592NCBI
Celera645,767,994 - 45,774,759 (+)NCBICelera
Cytogenetic Map6p21.1NCBI
HuRef643,935,917 - 43,943,640 (+)NCBIHuRef
CHM1_1644,217,626 - 44,225,330 (+)NCBICHM1_1
T2T-CHM13v2.0644,080,360 - 44,088,031 (+)NCBIT2T-CHM13v2.0
Hsp90ab1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391745,878,704 - 45,884,187 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1745,878,701 - 45,884,197 (-)EnsemblGRCm39 Ensembl
GRCm381745,567,778 - 45,573,261 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1745,567,775 - 45,573,271 (-)EnsemblGRCm38mm10GRCm38
MGSCv371745,704,727 - 45,710,210 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361745,031,359 - 45,036,842 (-)NCBIMGSCv36mm8
Celera1749,000,428 - 49,005,921 (-)NCBICelera
Cytogenetic Map17B3NCBI
cM Map1722.59NCBI
Hsp90ab1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8922,930,249 - 22,935,929 (+)NCBIGRCr8
mRatBN7.2915,432,986 - 15,438,358 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl915,433,691 - 15,438,488 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx924,019,488 - 24,024,885 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0929,082,165 - 29,087,562 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0927,382,927 - 27,388,324 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0917,817,791 - 17,823,163 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl917,817,721 - 17,823,243 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0916,706,512 - 16,711,884 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4911,033,496 - 11,038,868 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1911,030,786 - 11,036,319 (+)NCBI
Celera913,176,225 - 13,181,597 (+)NCBICelera
Cytogenetic Map9q12NCBI
Hsp90ab1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554379,873,908 - 9,878,459 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554379,872,649 - 9,878,459 (+)NCBIChiLan1.0ChiLan1.0
HSP90AB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2558,750,514 - 58,757,909 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1654,620,583 - 54,627,983 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0643,842,796 - 43,849,637 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1645,126,060 - 45,132,972 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl645,125,773 - 45,133,872 (+)Ensemblpanpan1.1panPan2
HSP90AB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11212,658,415 - 12,664,945 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1212,660,008 - 12,664,940 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1212,682,075 - 12,689,685 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01213,139,324 - 13,147,144 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1213,140,459 - 13,147,650 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11212,665,005 - 12,672,579 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01212,752,685 - 12,760,264 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01212,846,448 - 12,854,258 (+)NCBIUU_Cfam_GSD_1.0
Hsp90ab1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494648,123,181 - 48,129,743 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647615,830,459 - 15,835,535 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647615,830,459 - 15,836,994 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HSP90AB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11727,914,261 - 27,921,666 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1727,911,013 - 27,921,251 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604444,300,580 - 44,307,963 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hsp90ab1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475415,609,920 - 15,614,263 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475415,609,932 - 15,615,580 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in HSP90AB1
452 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001244433 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005666063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AEMK02000055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF288819 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK349158 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK390439 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK390441 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK392336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK398094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK398713 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK398794 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK399383 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK400498 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM268499 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP170278 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BW961399 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT009542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EW095226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FS645867 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FS677936 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GFLN01090742 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSSSCT00000001901   ⟹   ENSSSCP00000001854
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl739,244,743 - 39,250,206 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000038665   ⟹   ENSSSCP00000040559
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl739,244,743 - 39,254,002 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000044897   ⟹   ENSSSCP00000034120
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl739,244,743 - 39,254,002 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000045361   ⟹   ENSSSCP00000054197
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl739,244,981 - 39,250,481 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000054552   ⟹   ENSSSCP00000032023
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl739,244,458 - 39,250,481 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000061944   ⟹   ENSSSCP00000056745
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl739,244,743 - 39,250,312 (+)Ensembl
RefSeq Acc Id: NM_001244433   ⟹   NP_001231362
RefSeq Status: VALIDATED
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1739,243,774 - 39,250,479 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005666063   ⟹   XP_005666120
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1739,237,299 - 39,250,477 (+)NCBI
Sequence:
RefSeq Acc Id: XP_005666120   ⟸   XM_005666063
- Peptide Label: isoform X1
- UniProtKB: F1RQU2 (UniProtKB/TrEMBL),   A0A4X1V534 (UniProtKB/TrEMBL),   A0A8D0N653 (UniProtKB/TrEMBL),   A0A8D1I190 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001231362   ⟸   NM_001244433
- UniProtKB: F1RQU2 (UniProtKB/TrEMBL),   A0A4X1V534 (UniProtKB/TrEMBL),   A0A8D0N653 (UniProtKB/TrEMBL),   A0A8D1I190 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000032023   ⟸   ENSSSCT00000054552
Ensembl Acc Id: ENSSSCP00000034120   ⟸   ENSSSCT00000044897
Ensembl Acc Id: ENSSSCP00000001854   ⟸   ENSSSCT00000001901
Ensembl Acc Id: ENSSSCP00000054197   ⟸   ENSSSCT00000045361
Ensembl Acc Id: ENSSSCP00000056745   ⟸   ENSSSCT00000061944
Ensembl Acc Id: ENSSSCP00000040559   ⟸   ENSSSCT00000038665
Protein Domains
Histidine kinase/HSP90-like ATPase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000001701 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015025272 UniProtKB/TrEMBL
  ENSSSCG00025042198 UniProtKB/TrEMBL
  ENSSSCG00030067519 UniProtKB/TrEMBL
  ENSSSCG00040062099 UniProtKB/TrEMBL
  ENSSSCG00045021583 UniProtKB/TrEMBL
  ENSSSCG00055028008 UniProtKB/TrEMBL
  ENSSSCG00060023020 UniProtKB/TrEMBL
  ENSSSCG00065070167 UniProtKB/TrEMBL
  ENSSSCG00070021894 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000001901.4 UniProtKB/TrEMBL
  ENSSSCT00000045361 ENTREZGENE
  ENSSSCT00000045361.2 UniProtKB/TrEMBL
  ENSSSCT00000054552.2 UniProtKB/TrEMBL
  ENSSSCT00000061944.3 UniProtKB/TrEMBL
  ENSSSCT00015035023.1 UniProtKB/TrEMBL
  ENSSSCT00025058373.1 UniProtKB/TrEMBL
  ENSSSCT00030094597.1 UniProtKB/TrEMBL
  ENSSSCT00040085417.1 UniProtKB/TrEMBL
  ENSSSCT00045037656.1 UniProtKB/TrEMBL
  ENSSSCT00045037778.1 UniProtKB/TrEMBL
  ENSSSCT00045037875.1 UniProtKB/TrEMBL
  ENSSSCT00045037941.1 UniProtKB/TrEMBL
  ENSSSCT00045038021.1 UniProtKB/TrEMBL
  ENSSSCT00055055454.1 UniProtKB/TrEMBL
  ENSSSCT00055055521.1 UniProtKB/TrEMBL
  ENSSSCT00055055674.1 UniProtKB/TrEMBL
  ENSSSCT00055055721.1 UniProtKB/TrEMBL
  ENSSSCT00055055787.1 UniProtKB/TrEMBL
  ENSSSCT00055055896.1 UniProtKB/TrEMBL
  ENSSSCT00055055953.1 UniProtKB/TrEMBL
  ENSSSCT00055056008.1 UniProtKB/TrEMBL
  ENSSSCT00060031288.1 UniProtKB/TrEMBL
  ENSSSCT00065096415.1 UniProtKB/TrEMBL
  ENSSSCT00070043600.1 UniProtKB/TrEMBL
  ENSSSCT00070043610.1 UniProtKB/TrEMBL
  ENSSSCT00070043615.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.120.790 UniProtKB/TrEMBL
  3.30.230.80 UniProtKB/TrEMBL
  3.30.565.10 UniProtKB/TrEMBL
  3.40.50.11260 UniProtKB/TrEMBL
InterPro HATPase_C UniProtKB/TrEMBL
  HATPase_C_sf UniProtKB/TrEMBL
  Heat_shock_protein_90_CS UniProtKB/TrEMBL
  HSP90_C UniProtKB/TrEMBL
  Hsp90_fam UniProtKB/TrEMBL
  Hsp90_N UniProtKB/TrEMBL
  Ribosomal_S5_D2-typ_fold UniProtKB/TrEMBL
KEGG Report ssc:396742 UniProtKB/TrEMBL
NCBI Gene HSP90AB1 ENTREZGENE
PANTHER HEAT SHOCK PROTEIN HSP 90-BETA UniProtKB/TrEMBL
  PTHR11528 UniProtKB/TrEMBL
Pfam HATPase_c_3 UniProtKB/TrEMBL
  HSP90 UniProtKB/TrEMBL
PIRSF Hsp90 UniProtKB/TrEMBL
PRINTS HEATSHOCK90 UniProtKB/TrEMBL
PROSITE HSP90 UniProtKB/TrEMBL
SMART HATPase_c UniProtKB/TrEMBL
Superfamily-SCOP SSF110942 UniProtKB/TrEMBL
  SSF54211 UniProtKB/TrEMBL
  SSF55874 UniProtKB/TrEMBL
UniProt A0A286ZKC5_PIG UniProtKB/TrEMBL
  A0A287A9T4_PIG UniProtKB/TrEMBL
  A0A4X1V534 ENTREZGENE
  A0A4X1V543_PIG UniProtKB/TrEMBL
  A0A4X1V548_PIG UniProtKB/TrEMBL
  A0A8D0K8U4_PIG UniProtKB/TrEMBL
  A0A8D0N653 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1I190 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1SAM9_PIG UniProtKB/TrEMBL
  A0A8D1SET6_PIG UniProtKB/TrEMBL
  F1RQU2 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A287BDM6 UniProtKB/TrEMBL
  A0A287BK26 UniProtKB/TrEMBL