TFF1 (trefoil factor 1) - Rat Genome Database

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Gene: TFF1 (trefoil factor 1) Sus scrofa
Analyze
Symbol: TFF1
Name: trefoil factor 1
RGD ID: 13853271
Description: INVOLVED IN cell differentiation (ortholog); cell population proliferation (ortholog); maintenance of gastrointestinal epithelium (ortholog); PARTICIPATES IN forkhead class A signaling pathway; ASSOCIATED WITH Achlorhydria (ortholog); Acute Lung Injury (ortholog); Breast Neoplasms (ortholog); FOUND IN extracellular space (ortholog); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13205,687,560 - 205,691,460 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113205,687,558 - 205,691,512 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213216,090,047 - 216,093,946 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:19064270   PMID:19255509   PMID:30032202  


Genomics

Comparative Map Data
TFF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13205,687,560 - 205,691,460 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113205,687,558 - 205,691,512 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213216,090,047 - 216,093,946 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TFF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382142,362,282 - 42,366,535 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2142,362,282 - 42,366,535 (-)EnsemblGRCh38hg38GRCh38
GRCh372143,782,391 - 43,786,644 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362142,655,460 - 42,659,713 (-)NCBINCBI36Build 36hg18NCBI36
Build 342142,655,459 - 42,659,713NCBI
Celera2128,931,367 - 28,935,619 (-)NCBICelera
Cytogenetic Map21q22.3NCBI
HuRef2129,199,645 - 29,203,896 (-)NCBIHuRef
CHM1_12143,342,564 - 43,346,817 (-)NCBICHM1_1
T2T-CHM13v2.02140,751,729 - 40,755,982 (-)NCBIT2T-CHM13v2.0
Tff1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391731,380,369 - 31,384,034 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1731,380,369 - 31,384,251 (-)EnsemblGRCm39 Ensembl
GRCm381731,161,395 - 31,165,060 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1731,161,395 - 31,165,277 (-)EnsemblGRCm38mm10GRCm38
MGSCv371731,298,341 - 31,301,998 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361730,888,408 - 30,892,034 (-)NCBIMGSCv36mm8
Celera1732,078,643 - 32,082,300 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1715.8NCBI
Tff1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8209,237,095 - 9,240,956 (-)NCBIGRCr8
mRatBN7.2209,235,736 - 9,239,597 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl209,235,736 - 9,239,597 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx209,930,565 - 9,934,421 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0209,291,735 - 9,295,591 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0209,766,849 - 9,770,721 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0209,892,124 - 9,895,984 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl209,892,124 - 9,895,984 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02012,071,835 - 12,075,695 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4209,526,674 - 9,530,534 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1209,526,900 - 9,530,761 (-)NCBI
Celera2010,760,042 - 10,763,903 (-)NCBICelera
Cytogenetic Map20p12NCBI
Tff1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540739,363,693 - 39,365,724 (+)NCBIChiLan1.0ChiLan1.0
TFF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22238,417,954 - 38,422,193 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12133,270,372 - 33,274,614 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02128,669,323 - 28,673,556 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12141,988,039 - 41,992,270 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2141,988,039 - 41,992,270 (-)Ensemblpanpan1.1panPan2
TFF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13136,681,478 - 36,684,571 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3136,681,357 - 36,695,665 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3135,832,379 - 35,835,472 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03136,197,946 - 36,201,048 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3136,197,825 - 36,201,061 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13136,090,916 - 36,094,013 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03136,071,100 - 36,074,201 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03136,566,194 - 36,569,306 (-)NCBIUU_Cfam_GSD_1.0
TFF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1286,239,101 - 86,244,491 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl286,239,105 - 86,243,795 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605414,199,648 - 14,204,451 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in TFF1
210 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
mesenchyme
4 1

Sequence


Ensembl Acc Id: ENSSSCT00000057760   ⟹   ENSSSCP00000031403
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl13205,687,560 - 205,691,460 (-)Ensembl
RefSeq Acc Id: XM_003358973   ⟹   XP_003359021
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.113205,687,558 - 205,691,512 (-)NCBI
Sequence:
RefSeq Acc Id: XP_003359021   ⟸   XM_003358973
- UniProtKB: A0A286ZIY1 (UniProtKB/TrEMBL),   A0A4X1TFR4 (UniProtKB/TrEMBL),   A0A8D0SR84 (UniProtKB/TrEMBL),   A0A8D1E8G3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000031403   ⟸   ENSSSCT00000057760
Protein Domains
P-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000034731 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015036329 UniProtKB/TrEMBL
  ENSSSCG00025059990 UniProtKB/TrEMBL
  ENSSSCG00030060473 UniProtKB/TrEMBL
  ENSSSCG00035006146 UniProtKB/TrEMBL
  ENSSSCG00040033513 UniProtKB/TrEMBL
  ENSSSCG00045031070 UniProtKB/TrEMBL
  ENSSSCG00050043089 UniProtKB/TrEMBL
  ENSSSCG00055016855 UniProtKB/TrEMBL
  ENSSSCG00060011322 UniProtKB/TrEMBL
  ENSSSCG00065021117 UniProtKB/TrEMBL
  ENSSSCG00070009078 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000057760 ENTREZGENE
  ENSSSCT00000057760.3 UniProtKB/TrEMBL
  ENSSSCT00015048182.1 UniProtKB/TrEMBL
  ENSSSCT00015048246.1 UniProtKB/TrEMBL
  ENSSSCT00025082086.1 UniProtKB/TrEMBL
  ENSSSCT00030084428.1 UniProtKB/TrEMBL
  ENSSSCT00035007660.1 UniProtKB/TrEMBL
  ENSSSCT00040045100.1 UniProtKB/TrEMBL
  ENSSSCT00045052919.1 UniProtKB/TrEMBL
  ENSSSCT00050058584.1 UniProtKB/TrEMBL
  ENSSSCT00055033210.1 UniProtKB/TrEMBL
  ENSSSCT00060014781.1 UniProtKB/TrEMBL
  ENSSSCT00065028096.1 UniProtKB/TrEMBL
  ENSSSCT00070017606.1 UniProtKB/TrEMBL
Gene3D-CATH 4.10.110.10 UniProtKB/TrEMBL
InterPro P_trefoil_chordata UniProtKB/TrEMBL
  P_trefoil_CS UniProtKB/TrEMBL
  P_trefoil_dom UniProtKB/TrEMBL
  P_trefoil_dom_sf UniProtKB/TrEMBL
KEGG Report ssc:780401 UniProtKB/TrEMBL
NCBI Gene TFF1 ENTREZGENE
PANTHER PTHR13826 UniProtKB/TrEMBL
  TREFOIL FACTOR 1 UniProtKB/TrEMBL
Pfam Trefoil UniProtKB/TrEMBL
PRINTS PTREFOIL UniProtKB/TrEMBL
PROSITE P_TREFOIL_1 UniProtKB/TrEMBL
  P_TREFOIL_2 UniProtKB/TrEMBL
SMART SM00018 UniProtKB/TrEMBL
Superfamily-SCOP SSF57492 UniProtKB/TrEMBL
UniProt A0A286ZIY1 ENTREZGENE
  A0A4X1TFR4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0SR84 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1E8G3 ENTREZGENE, UniProtKB/TrEMBL
  Q0VTR3_PIG UniProtKB/TrEMBL
UniProt Secondary A0A286ZIY1 UniProtKB/TrEMBL
VGNC ID VGNC:93919 ENTREZGENE