SST (somatostatin) - Rat Genome Database

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Gene: SST (somatostatin) Sus scrofa
Analyze
Symbol: SST
Name: somatostatin
RGD ID: 13843268
Description: ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN hyperosmotic response (ortholog); regulation of cell migration (ortholog); response to acidic pH (ortholog); PARTICIPATES IN cimetidine pharmacodynamics pathway; esomeprazole pharmacodynamics pathway; famotidine pharmacodynamics pathway; ASSOCIATED WITH Barrett's esophagus (ortholog); disease of cellular proliferation (ortholog); endometriosis (ortholog); FOUND IN cytosol (ortholog); extracellular space (ortholog); GABA-ergic synapse (ortholog); INTERACTS WITH copper(II) sulfate
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: SRIF
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13125,337,418 - 125,338,850 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113125,337,560 - 125,338,742 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213134,621,119 - 134,622,301 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:1252409   PMID:2567292   PMID:2865169   PMID:6107906   PMID:7353633   PMID:12646058   PMID:14681463   PMID:15679890   PMID:17145712   PMID:18753129   PMID:22301074   PMID:30032202  
PMID:34314850  


Genomics

Comparative Map Data
SST
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13125,337,418 - 125,338,850 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113125,337,560 - 125,338,742 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213134,621,119 - 134,622,301 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SST
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383187,668,912 - 187,670,394 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3187,668,912 - 187,670,394 (-)EnsemblGRCh38hg38GRCh38
GRCh373187,386,700 - 187,388,182 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363188,869,388 - 188,870,895 (-)NCBINCBI36Build 36hg18NCBI36
Build 343188,869,406 - 188,870,808NCBI
Celera3185,817,667 - 185,819,174 (-)NCBICelera
Cytogenetic Map3q27.3NCBI
HuRef3184,791,007 - 184,792,514 (-)NCBIHuRef
CHM1_13187,349,954 - 187,351,461 (-)NCBICHM1_1
T2T-CHM13v2.03190,486,363 - 190,487,845 (-)NCBIT2T-CHM13v2.0
Sst
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391623,708,327 - 23,710,041 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1623,708,323 - 23,709,708 (-)EnsemblGRCm39 Ensembl
GRCm381623,889,573 - 23,891,342 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1623,889,573 - 23,890,958 (-)EnsemblGRCm38mm10GRCm38
MGSCv371623,889,667 - 23,890,930 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361623,804,930 - 23,806,193 (-)NCBIMGSCv36mm8
Celera1624,439,585 - 24,440,848 (-)NCBICelera
Cytogenetic Map16B1NCBI
cM Map1615.0NCBI
Sst
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81190,461,546 - 90,462,823 (+)NCBIGRCr8
mRatBN7.21176,956,896 - 76,958,173 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1176,956,896 - 76,958,173 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1185,714,888 - 85,716,167 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01178,350,097 - 78,351,376 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01177,429,193 - 77,430,472 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01180,358,172 - 80,359,449 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1180,358,211 - 80,359,444 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01180,374,262 - 80,375,447 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41179,125,031 - 79,126,216 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11179,182,619 - 79,183,805 (+)NCBI
Celera1175,836,256 - 75,837,533 (+)NCBICelera
RH 3.4 Map11640.6RGD
Cytogenetic Map11q23NCBI
SST
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22185,539,811 - 185,541,321 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13185,544,525 - 185,546,059 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03184,695,561 - 184,697,091 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13193,156,526 - 193,158,020 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3193,155,363 - 193,158,337 (-)Ensemblpanpan1.1panPan2
SST
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13420,063,091 - 20,064,520 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3420,063,090 - 20,064,557 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3424,155,973 - 24,157,402 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03419,983,105 - 19,984,534 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3419,983,111 - 19,984,571 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13420,011,742 - 20,013,171 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03420,005,493 - 20,006,922 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03420,245,365 - 20,246,794 (-)NCBIUU_Cfam_GSD_1.0
Sst
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602116,372,454 - 116,373,819 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365782,464,212 - 2,465,701 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365782,464,310 - 2,465,673 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SST
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11581,946,287 - 81,947,775 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1581,946,206 - 81,947,790 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604155,444,092 - 55,445,581 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sst
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473069,213,781 - 69,215,477 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473069,213,917 - 69,215,296 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SST
17 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
8 1 21 2 1 7 5 21 2

Sequence


Ensembl Acc Id: ENSSSCT00000046992   ⟹   ENSSSCP00000051543
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl13125,337,418 - 125,338,850 (-)Ensembl
RefSeq Acc Id: NM_001009583   ⟹   NP_001009583
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.113125,337,560 - 125,338,742 (-)NCBI
Sequence:
RefSeq Acc Id: NP_001009583   ⟸   NM_001009583
- Peptide Label: precursor
- UniProtKB: Q6PLR2 (UniProtKB/Swiss-Prot),   P01168 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSSSCP00000051543   ⟸   ENSSSCT00000046992


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000033815 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSSSCG00005039932 UniProtKB/Swiss-Prot
  ENSSSCG00015014739 UniProtKB/Swiss-Prot
  ENSSSCG00025002914 UniProtKB/Swiss-Prot
  ENSSSCG00030011101 UniProtKB/Swiss-Prot
  ENSSSCG00035080964 UniProtKB/Swiss-Prot
  ENSSSCG00040070574 UniProtKB/Swiss-Prot
  ENSSSCG00045001202 UniProtKB/Swiss-Prot
  ENSSSCG00050056257 UniProtKB/Swiss-Prot
  ENSSSCG00055019804 UniProtKB/Swiss-Prot
  ENSSSCG00060051531 UniProtKB/Swiss-Prot
  ENSSSCG00065015354 UniProtKB/Swiss-Prot
  ENSSSCG00070016293 UniProtKB/Swiss-Prot
Ensembl Transcript ENSSSCT00000046992 ENTREZGENE
  ENSSSCT00000046992.3 UniProtKB/Swiss-Prot
  ENSSSCT00005063877 UniProtKB/Swiss-Prot
  ENSSSCT00015019504.1 UniProtKB/Swiss-Prot
  ENSSSCT00025003825.1 UniProtKB/Swiss-Prot
  ENSSSCT00030015223.1 UniProtKB/Swiss-Prot
  ENSSSCT00035111155.1 UniProtKB/Swiss-Prot
  ENSSSCT00040096870.1 UniProtKB/Swiss-Prot
  ENSSSCT00045001853.1 UniProtKB/Swiss-Prot
  ENSSSCT00050076731.1 UniProtKB/Swiss-Prot
  ENSSSCT00055038776.1 UniProtKB/Swiss-Prot
  ENSSSCT00060070140.1 UniProtKB/Swiss-Prot
  ENSSSCT00065020382.1 UniProtKB/Swiss-Prot
  ENSSSCT00070032031.1 UniProtKB/Swiss-Prot
InterPro Somatostatin UniProtKB/Swiss-Prot
  Somatostatin/Cortistatin_C UniProtKB/Swiss-Prot
KEGG Report ssc:494469 UniProtKB/Swiss-Prot
NCBI Gene SST ENTREZGENE
PANTHER PTHR10558 UniProtKB/Swiss-Prot
  SOMATOSTATIN UniProtKB/Swiss-Prot
Pfam Somatostatin UniProtKB/Swiss-Prot
PIRSF Somatostatin UniProtKB/Swiss-Prot
UniProt P01168 ENTREZGENE
  Q6PLR2 ENTREZGENE
  SMS_PIG UniProtKB/Swiss-Prot
UniProt Secondary Q6PLR2 UniProtKB/Swiss-Prot
VGNC ID VGNC:93495 ENTREZGENE