Fh<sup>em1</sup> (fumarate hydratase; TALEN induced mutant 1) - Rat Genome Database

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Gene: Fhem1 (fumarate hydratase; TALEN induced mutant 1) Rattus norvegicus
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Symbol: Fhem1
Name: fumarate hydratase; TALEN induced mutant 1
RGD ID: 13792797
Description: A pair of TALENs targeting exon 1 of the Fh gene was injected into SD embryos to create Fh knock out mutants. The resulting mutation was an 11-bp deletion (acacctttggt) on exon 1 that caused premature stop of FH protein.
ASSOCIATED WITH abnormal kidney morphology; abnormal lymphocyte morphology; decreased blood uric acid level
Type: allele  of Fh  
Is Marker For: Strains:   SD-Fhem1+/-  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position: No map positions available.


References

References - curated
1. Yu D, etal., Oncotarget. 2016 Sep 20;7(38):61656-61669. doi: 10.18632/oncotarget.11429.

Genomics


Related Rat Strains
The following Strains have been annotated to Fhem1


Expression


Sequence

Nucleotide Sequences


Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-09-28 Fhem1  fumarate hydratase; TALEN induced mutant 1  Fhem1    Name changed 629549 APPROVED