Cdk9 (cyclin-dependent kinase 9) - Rat Genome Database

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Gene: Cdk9 (cyclin-dependent kinase 9) Rattus norvegicus
Analyze
Symbol: Cdk9
Name: cyclin-dependent kinase 9
RGD ID: 1359638
Description: Enables chromatin binding activity. Involved in positive regulation of cardiac muscle hypertrophy and response to xenobiotic stimulus. Predicted to be located in PML body and cytoplasmic ribonucleoprotein granule. Predicted to be part of P-TEFb complex. Predicted to be active in nucleus. Orthologous to human CDK9 (cyclin dependent kinase 9); PARTICIPATES IN RNA polymerase II transcription elongation pathway; RNA polymerase II transcription pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: cell division protein kinase 9; cyclin-dependent kinase 9 (CDC2-related kinase); MGC95175
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8336,394,168 - 36,399,016 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl336,394,169 - 36,399,528 (-)EnsemblGRCr8
mRatBN7.2315,996,467 - 16,001,315 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl315,996,468 - 16,002,410 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx319,065,041 - 19,069,877 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0327,650,044 - 27,654,880 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0325,901,304 - 25,906,154 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0311,742,269 - 11,747,117 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl311,742,266 - 11,747,113 (-)Ensemblrn6Rnor6.0
Rnor_5.0317,081,164 - 17,086,012 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4311,672,861 - 11,677,709 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera310,737,357 - 10,742,205 (-)NCBICelera
RGSC_v3.1311,569,232 - 11,574,081 (-)NCBI
Cytogenetic Map3p11NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP,ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,4-dinitrotoluene  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxynon-2-enal  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
alvocidib  (ISO)
Aroclor 1254  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
berberine  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP)
bisphenol F  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
Cinobufagin  (ISO)
clofibrate  (ISO)
curcumin  (ISO)
cyclosporin A  (ISO)
cypermethrin  (EXP)
D-glucose  (ISO)
decabromodiphenyl ether  (ISO)
deferasirox  (ISO)
dexamethasone  (ISO)
diazinon  (EXP)
dimethylarsinic acid  (EXP)
dinaciclib  (ISO)
disodium selenite  (ISO)
divanadium pentaoxide  (ISO)
doxorubicin  (ISO)
enzyme inhibitor  (ISO)
fenofibrate  (EXP)
fenvalerate  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
glucose  (ISO)
GSK-J4  (ISO)
hydrogen peroxide  (ISO)
indometacin  (ISO)
ivermectin  (ISO)
lipopolysaccharide  (ISO)
lycopene  (ISO)
methamphetamine  (ISO)
nickel dichloride  (EXP)
nitrates  (ISO)
ozone  (ISO)
paracetamol  (ISO)
perfluorooctanoic acid  (ISO)
PhIP  (ISO)
progesterone  (ISO)
quercetin  (ISO)
rucaparib  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sorafenib  (ISO)
streptozocin  (EXP,ISO)
sunitinib  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
urethane  (ISO)
valproic acid  (ISO)
wogonin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Updating the RNA polymerase CTD code: adding gene-specific layers. Egloff S, etal., Trends Genet. 2012 Jul;28(7):333-41. doi: 10.1016/j.tig.2012.03.007. Epub 2012 May 21.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. The writers, readers, and functions of the RNA polymerase II C-terminal domain code. Jeronimo C, etal., Chem Rev. 2013 Nov 13;113(11):8491-522. doi: 10.1021/cr4001397. Epub 2013 Jul 10.
4. Control of transcriptional elongation. Kwak H and Lis JT, Annu Rev Genet. 2013;47:483-508. doi: 10.1146/annurev-genet-110711-155440. Epub 2013 Sep 11.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Activation of cardiac Cdk9 represses PGC-1 and confers a predisposition to heart failure. Sano M, etal., EMBO J 2004 Sep 1;23(17):3559-69. Epub 2004 Aug 5.
9. Activation of MyoD-dependent transcription by cdk9/cyclin T2. Simone C, etal., Oncogene 2002 Jun 13;21(26):4137-48.
10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
11. Cyclin-dependent kinase-9 is a component of the p300/GATA4 complex required for phenylephrine-induced hypertrophy in cardiomyocytes. Sunagawa Y, etal., J Biol Chem. 2010 Mar 26;285(13):9556-68. doi: 10.1074/jbc.M109.070458. Epub 2010 Jan 17.
12. Protective effect of berberine on antioxidant enzymes and positive transcription elongation factor b expression in diabetic rat liver. Zhou JY and Zhou SW, Fitoterapia. 2011 Mar;82(2):184-9. doi: 10.1016/j.fitote.2010.08.019. Epub 2010 Sep 7.
Additional References at PubMed
PMID:9499409   PMID:11713533   PMID:12037672   PMID:12721286   PMID:15489334   PMID:15905409   PMID:16109376   PMID:16245309   PMID:17700062   PMID:17956865   PMID:18250157   PMID:19575011  
PMID:19844166   PMID:19946888   PMID:20493174   PMID:20570862   PMID:20930849   PMID:21245044   PMID:22195968   PMID:22509028   PMID:22547058   PMID:22767893   PMID:23154982   PMID:23752591  
PMID:28426094   PMID:32341082   PMID:38167752  


Genomics

Comparative Map Data
Cdk9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8336,394,168 - 36,399,016 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl336,394,169 - 36,399,528 (-)EnsemblGRCr8
mRatBN7.2315,996,467 - 16,001,315 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl315,996,468 - 16,002,410 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx319,065,041 - 19,069,877 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0327,650,044 - 27,654,880 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0325,901,304 - 25,906,154 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0311,742,269 - 11,747,117 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl311,742,266 - 11,747,113 (-)Ensemblrn6Rnor6.0
Rnor_5.0317,081,164 - 17,086,012 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4311,672,861 - 11,677,709 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera310,737,357 - 10,742,205 (-)NCBICelera
RGSC_v3.1311,569,232 - 11,574,081 (-)NCBI
Cytogenetic Map3p11NCBI
CDK9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389127,786,034 - 127,790,792 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9127,785,679 - 127,790,792 (+)Ensemblhg38GRCh38
GRCh379130,548,313 - 130,553,071 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369129,588,152 - 129,592,184 (+)NCBIBuild 36Build 36hg18NCBI36
Build 349127,627,890 - 127,631,917NCBI
Celera9101,199,168 - 101,203,915 (+)NCBICelera
Cytogenetic Map9q34.11NCBI
HuRef9100,164,574 - 100,169,598 (+)NCBIHuRef
CHM1_19130,699,854 - 130,704,602 (+)NCBICHM1_1
T2T-CHM13v2.09139,993,485 - 139,998,243 (+)NCBIT2T-CHM13v2.0
Cdk9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39232,595,794 - 32,608,098 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl232,595,796 - 32,603,088 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38232,705,782 - 32,712,784 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl232,705,784 - 32,713,076 (-)Ensemblmm10GRCm38
MGSCv37232,561,302 - 32,568,304 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36232,529,447 - 32,534,794 (-)NCBIMGSCv36mm8
Celera232,412,389 - 32,419,391 (-)NCBICelera
Cytogenetic Map2BNCBI
cM Map222.09NCBI
Cdk9
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955419873,289 - 883,160 (-)Ensembl
ChiLan1.0NW_004955419874,959 - 883,160 (-)NCBIChiLan1.0ChiLan1.0
CDK9
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21111,558,761 - 11,569,295 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1911,561,106 - 11,571,580 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0998,905,468 - 98,909,923 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19127,580,862 - 127,584,936 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9127,580,862 - 127,584,935 (+)EnsemblpanPan2panpan1.1
CDK9
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1955,615,271 - 55,619,493 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl955,615,827 - 55,620,236 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha954,808,829 - 54,812,940 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0956,536,951 - 56,541,065 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl956,536,954 - 56,541,348 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1955,296,987 - 55,301,098 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0955,611,719 - 55,615,827 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0955,703,144 - 55,707,256 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cdk9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947195,678,357 - 195,682,223 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648715,446,858 - 15,452,796 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493648715,446,864 - 15,450,750 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDK9
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1268,276,841 - 268,281,052 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11268,277,083 - 268,280,493 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21302,142,973 - 302,146,162 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CDK9
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11210,342,240 - 10,346,792 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1210,342,801 - 10,346,502 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660795,874,123 - 5,879,334 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cdk9
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247607,760,474 - 7,765,711 (-)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Cdk9
18 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:376
Count of miRNA genes:220
Interacting mature miRNAs:258
Transcripts:ENSRNOT00000032893
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358357Srcrtb1Stress Responsive Cort Basal QTL 16.360.002blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)3865816227494778Rat
6893355Bw101Body weight QTL 1010.40.38body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
10401810Kidm53Kidney mass QTL 53kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3822719447233430Rat
1298526Arunc3Aerobic running capacity QTL 32.2exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)3822719433703538Rat
8693641Alc30Alcohol consumption QTL 3020.739drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)31043430624512004Rat
2298542Neuinf11Neuroinflammation QTL 113.9nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)31500542276927699Rat
1558657Cm43Cardiac mass QTL 436.63e-08heart mass (VT:0007028)heart wet weight (CMO:0000069)31077882330356773Rat
631568Bp92Blood pressure QTL 922.20.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3139874793Rat
6893363Bw105Body weight QTL 1052.60.0036body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)pulse pressure (CMO:0000292)3133278763Rat
631831Alc8Alcohol consumption QTL 82.7consumption behavior trait (VT:0002069)calculated ethanol drink intake rate (CMO:0001615)3133230976Rat
1558647Cm46Cardiac mass QTL 465.40.0000055heart mass (VT:0007028)heart wet weight (CMO:0000069)31077882330356773Rat
4889966Bss95Bone structure and strength QTL 954.4tibia area (VT:1000281)tibia-fibula cross-sectional area (CMO:0001718)3136847613Rat
1558654Bw56Body weight QTL 564.50.0000171body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
1558650Cm48Cardiac mass QTL 4840.0001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)31077882330356773Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)31086191289878372Rat
70191BpQTLcluster4Blood pressure QTL cluster 43arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)31077870450302886Rat
631545Bp85Blood pressure QTL 853.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3133278763Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
631679Cm10Cardiac mass QTL 107.340.0001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3131158234Rat
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3191609953Rat
70203Gcr2Gastric cancer resistance QTL 22.6stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)3865816227494778Rat
70202Alc19Alcohol consumption QTL 192.5drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)3127494778Rat
2312664Scl62Serum cholesterol level QTL 620.05blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)3138710544Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat

Markers in Region
RH129246  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2315,996,557 - 15,996,773 (+)MAPPERmRatBN7.2
Rnor_6.0311,742,360 - 11,742,575NCBIRnor6.0
Rnor_5.0317,081,255 - 17,081,470UniSTSRnor5.0
RGSC_v3.4311,672,952 - 11,673,167UniSTSRGSC3.4
Celera310,737,448 - 10,737,663UniSTS
RH 3.4 Map370.3UniSTS
Cytogenetic Map3p11UniSTS
Cdk9  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2315,996,503 - 15,998,178 (+)MAPPERmRatBN7.2
Rnor_6.0311,742,306 - 11,743,980NCBIRnor6.0
Rnor_5.0317,081,201 - 17,082,875UniSTSRnor5.0
RGSC_v3.4311,672,898 - 11,674,572UniSTSRGSC3.4
Celera310,737,394 - 10,739,068UniSTS
Cytogenetic Map3p11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000032893   ⟹   ENSRNOP00000037778
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl336,394,169 - 36,399,528 (-)Ensembl
mRatBN7.2 Ensembl315,996,468 - 16,002,410 (-)Ensembl
Rnor_6.0 Ensembl311,742,266 - 11,747,113 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000151968   ⟹   ENSRNOP00000110396
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl336,394,169 - 36,399,528 (-)Ensembl
RefSeq Acc Id: NM_001007743   ⟹   NP_001007744
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8336,394,168 - 36,399,016 (-)NCBI
mRatBN7.2315,996,467 - 16,001,315 (-)NCBI
Rnor_6.0311,742,269 - 11,747,117 (-)NCBI
Rnor_5.0317,081,164 - 17,086,012 (-)NCBI
RGSC_v3.4311,672,861 - 11,677,709 (-)RGD
Celera310,737,357 - 10,742,205 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001007744 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH82037 (Get FASTA)   NCBI Sequence Viewer  
  EDL93216 (Get FASTA)   NCBI Sequence Viewer  
  EDL93217 (Get FASTA)   NCBI Sequence Viewer  
  EDL93218 (Get FASTA)   NCBI Sequence Viewer  
  Q641Z4 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001007744   ⟸   NM_001007743
- UniProtKB: Q641Z4 (UniProtKB/Swiss-Prot),   A6JU80 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000037778   ⟸   ENSRNOT00000032893
Ensembl Acc Id: ENSRNOP00000110396   ⟸   ENSRNOT00000151968
Protein Domains
Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q641Z4-F1-model_v2 AlphaFold Q641Z4 1-372 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691991
Promoter ID:EPDNEW_R2516
Type:initiation region
Name:Cdk9_1
Description:cyclin-dependent kinase 9
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0311,747,183 - 11,747,243EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359638 AgrOrtholog
BioCyc Gene G2FUF-50126 BioCyc
Ensembl Genes ENSRNOG00000022586 Ensembl
Gene3D-CATH Phosphorylase Kinase, domain 1 UniProtKB/Swiss-Prot
  Transferase(Phosphotransferase) domain 1 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7130973 IMAGE-MGC_LOAD
InterPro CDK UniProtKB/Swiss-Prot
  Kinase-like_dom_sf UniProtKB/Swiss-Prot
  Prot_kinase_dom UniProtKB/Swiss-Prot
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot
  Ser/Thr_kinase_AS UniProtKB/Swiss-Prot
KEGG Report rno:362110 UniProtKB/Swiss-Prot
MGC_CLONE MGC:95175 IMAGE-MGC_LOAD
NCBI Gene 362110 ENTREZGENE
PANTHER CELL DIVISION PROTEIN KINASE UniProtKB/Swiss-Prot
  CYCLIN-DEPENDENT KINASE 9 UniProtKB/Swiss-Prot
Pfam Pkinase UniProtKB/Swiss-Prot
PhenoGen Cdk9 PhenoGen
PROSITE PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot
  PROTEIN_KINASE_ST UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000022586 RatGTEx
SMART S_TKc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF56112 UniProtKB/Swiss-Prot
UniProt A0A8L2QJI9_RAT UniProtKB/TrEMBL
  A6JU79_RAT UniProtKB/TrEMBL
  A6JU80 ENTREZGENE, UniProtKB/TrEMBL
  A6JU81_RAT UniProtKB/TrEMBL
  CDK9_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-09-09 Cdk9  cyclin-dependent kinase 9  Cdk9  cyclin-dependent kinase 9 (CDC2-related kinase)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Cdk9  cyclin-dependent kinase 9 (CDC2-related kinase)    cyclin-dependent kinase 9  Name updated 1299863 APPROVED
2005-07-29 Cdk9  cyclin-dependent kinase 9      Symbol and Name status set to provisional 70820 PROVISIONAL