Fblim1 (filamin binding LIM protein 1) - Rat Genome Database

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Gene: Fblim1 (filamin binding LIM protein 1) Rattus norvegicus
Analyze
Symbol: Fblim1
Name: filamin binding LIM protein 1
RGD ID: 1359551
Description: Predicted to enable filamin binding activity; pre-mRNA intronic binding activity; and transcription cis-regulatory region binding activity. Predicted to be involved in cell-cell adhesion; regulation of RNA metabolic process; and regulation of integrin activation. Predicted to be located in several cellular components, including chromatin; nuclear lumen; and ribonucleoprotein granule. Predicted to be part of ribonucleoprotein complex. Predicted to be active in focal adhesion and stress fiber. Orthologous to human FBLIM1 (filamin binding LIM protein 1); PARTICIPATES IN integrin mediated signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Cal; CSX-associated LIM; filamin-binding LIM protein 1; heterogeneous nuclear ribonucleoprotein L; hnRNP L; Hnrnpl; MGC105665
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85159,167,004 - 159,198,578 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5159,167,004 - 159,196,853 (-)EnsemblGRCr8
mRatBN7.25153,883,945 - 153,915,524 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5153,883,960 - 153,913,757 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5156,568,849 - 156,598,883 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05158,342,136 - 158,372,165 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05158,331,314 - 158,361,338 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05160,122,466 - 160,158,921 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5160,122,425 - 160,158,386 (-)Ensemblrn6Rnor6.0
Rnor_5.05163,841,377 - 163,867,441 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45160,468,558 - 160,495,015 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5152,241,216 - 152,267,207 (-)NCBICelera
RGSC_v3.15160,478,745 - 160,505,203 (-)NCBI
Cytogenetic Map5q36NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,6-dimethoxyphenol  (ISO)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxyphenyl retinamide  (ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (EXP)
alpha-Zearalanol  (EXP)
amphetamine  (EXP)
aristolochic acid A  (ISO)
benzo[a]pyrene  (ISO)
beta-naphthoflavone  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP)
bisphenol F  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloroprene  (ISO)
cisplatin  (EXP)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
decabromodiphenyl ether  (EXP)
dextran sulfate  (ISO)
dibutyl phthalate  (EXP)
dorsomorphin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
Evodiamine  (ISO)
ferric oxide  (ISO)
folic acid  (ISO)
furan  (EXP)
furfural  (ISO)
gentamycin  (EXP)
inulin  (ISO)
isoprenaline  (ISO)
ivermectin  (ISO)
ketamine  (EXP)
lead diacetate  (ISO)
lipopolysaccharide  (ISO)
mercury dibromide  (ISO)
methamphetamine  (EXP)
methylmercury chloride  (ISO)
morphine  (EXP)
N-nitrosodiethylamine  (EXP,ISO)
N-Nitrosopyrrolidine  (ISO)
nitrofen  (EXP)
O-methyleugenol  (ISO)
oxaliplatin  (EXP)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
phenylmercury acetate  (ISO)
potassium chromate  (ISO)
potassium dichromate  (ISO)
propanal  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
sodium fluoride  (ISO)
Soman  (EXP)
sunitinib  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thiram  (ISO)
topotecan  (EXP)
trimellitic anhydride  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Talins and kindlins: partners in integrin-mediated adhesion. Calderwood DA, etal., Nat Rev Mol Cell Biol. 2013 Aug;14(8):503-17. doi: 10.1038/nrm3624. Epub 2013 Jul 17.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
8. A new member of the LIM protein family binds to filamin B and localizes at stress fibers. Takafuta T, etal., J Biol Chem 2003 Apr 4;278(14):12175-81. Epub 2002 Dec 20.
Additional References at PubMed
PMID:18829455   PMID:19074766   PMID:21423176  


Genomics

Comparative Map Data
Fblim1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85159,167,004 - 159,198,578 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5159,167,004 - 159,196,853 (-)EnsemblGRCr8
mRatBN7.25153,883,945 - 153,915,524 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5153,883,960 - 153,913,757 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5156,568,849 - 156,598,883 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05158,342,136 - 158,372,165 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05158,331,314 - 158,361,338 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05160,122,466 - 160,158,921 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5160,122,425 - 160,158,386 (-)Ensemblrn6Rnor6.0
Rnor_5.05163,841,377 - 163,867,441 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45160,468,558 - 160,495,015 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5152,241,216 - 152,267,207 (-)NCBICelera
RGSC_v3.15160,478,745 - 160,505,203 (-)NCBI
Cytogenetic Map5q36NCBI
FBLIM1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38115,756,638 - 15,786,589 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl115,756,607 - 15,786,594 (+)Ensemblhg38GRCh38
GRCh37116,083,133 - 16,113,084 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36115,957,842 - 15,985,671 (+)NCBIBuild 36Build 36hg18NCBI36
Celera114,568,272 - 14,596,101 (+)NCBICelera
Cytogenetic Map1p36.21NCBI
HuRef114,604,147 - 14,633,154 (+)NCBIHuRef
CHM1_1115,883,844 - 15,911,675 (+)NCBICHM1_1
T2T-CHM13v2.0115,201,378 - 15,231,333 (+)NCBIT2T-CHM13v2.0
Fblim1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394141,303,373 - 141,333,351 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4141,303,373 - 141,333,407 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm384141,576,062 - 141,606,052 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4141,576,062 - 141,606,096 (-)Ensemblmm10GRCm38
MGSCv374141,131,977 - 141,161,967 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv364140,849,005 - 140,868,028 (-)NCBIMGSCv36mm8
Celera4143,398,852 - 143,428,836 (-)NCBICelera
Cytogenetic Map4D3NCBI
cM Map474.64NCBI
Fblim1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555272,400,218 - 2,415,051 (-)Ensembl
ChiLan1.0NW_0049555272,399,804 - 2,418,160 (-)NCBIChiLan1.0ChiLan1.0
FBLIM1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21211,129,565 - 211,159,464 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11210,378,150 - 210,408,064 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0114,898,987 - 14,928,887 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1115,890,592 - 15,921,557 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl115,890,600 - 15,921,558 (+)EnsemblpanPan2panpan1.1
FBLIM1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1281,820,129 - 81,837,617 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl281,821,291 - 81,838,306 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha278,358,519 - 78,382,681 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0282,468,984 - 82,493,387 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl282,468,997 - 82,491,099 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1279,222,455 - 79,246,609 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0280,240,491 - 80,264,810 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0281,306,542 - 81,330,706 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Fblim1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505837,559,213 - 37,575,078 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364743,384,043 - 3,398,907 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364743,386,279 - 3,398,880 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FBLIM1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl674,929,932 - 74,966,942 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1674,929,830 - 74,964,166 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2669,342,884 - 69,375,270 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FBLIM1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120116,518,768 - 116,545,907 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20116,518,679 - 116,546,280 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605420,052,373 - 20,081,897 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Fblim1
211 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:44
Count of miRNA genes:38
Interacting mature miRNAs:44
Transcripts:ENSRNOT00000045237
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5111416838156416838Rat
2302369Scl60Serum cholesterol level QTL 603.13blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)5143608201161165651Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5135927956166875058Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5135929696166875058Rat
1300119Bp180Blood pressure QTL 1803.82arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5144358090157869054Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5131345754166875058Rat
1354631Swd2Spike wave discharge measurement QTL 23.640.0002brain electrophysiology trait (VT:0010557)brain total spike-and-wave discharge duration (CMO:0001740)5151113452164465185Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5127798274166875058Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
631263Cm24Cardiac mass QTL 243.5heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)5143799107158428037Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5132717196165560427Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5121846814166846814Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5128506074166875058Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5143069996166846814Rat
8657050Bw146Body weight QTL 14619.840.001body mass (VT:0001259)body weight gain (CMO:0000420)5108938288153938288Rat
631272Lanf1Left ventricular atrial natriuretic factor QTL 112heart left ventricle natriuretic peptide A amount (VT:0010596)heart left ventricle natriuretic peptide A level (CMO:0002165)5151113452166875058Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
634349Bp139Blood pressure QTL 1390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5128924607166875058Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5126424772166875058Rat
738018Anxrr4Anxiety related response QTL 45.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)5130130159166875058Rat
2313096Bmd78Bone mineral density QTL 783.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)5144377876161317411Rat
8694441Bw169Body weight QTL 16917.610.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)5111416838156416838Rat
8694389Bw160Body weight QTL 1606.170.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)5111416838156416838Rat
8694198Abfw3Abdominal fat weight QTL 316.130.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)5111416838156416838Rat
1298090Bp155Blood pressure QTL 1553.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)5151006154161165494Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5127798274166875058Rat

Markers in Region
BE116703  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25153,887,111 - 153,887,281 (+)MAPPERmRatBN7.2
Rnor_6.05160,125,629 - 160,125,798NCBIRnor6.0
Rnor_5.05163,844,539 - 163,844,708UniSTSRnor5.0
RGSC_v3.45160,471,721 - 160,471,890UniSTSRGSC3.4
Celera5152,244,425 - 152,244,594UniSTS
RH 3.4 Map51051.8UniSTS
Cytogenetic Map5q36UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
22 12 82 171 91 90 59 74 59 6 397 194 17 149 114 123 31 23 23

Sequence


Ensembl Acc Id: ENSRNOT00000045237   ⟹   ENSRNOP00000040868
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5159,167,004 - 159,196,853 (-)Ensembl
mRatBN7.2 Ensembl5153,883,960 - 153,910,213 (-)Ensembl
Rnor_6.0 Ensembl5160,122,467 - 160,156,209 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000089345   ⟹   ENSRNOP00000074912
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5159,167,004 - 159,196,816 (-)Ensembl
mRatBN7.2 Ensembl5153,883,960 - 153,913,757 (-)Ensembl
Rnor_6.0 Ensembl5160,122,425 - 160,158,386 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000133282   ⟹   ENSRNOP00000099565
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5159,167,004 - 159,196,686 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000148404   ⟹   ENSRNOP00000102131
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5159,167,004 - 159,195,698 (-)Ensembl
RefSeq Acc Id: NM_001007554   ⟹   NP_001007555
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85159,167,004 - 159,196,816 (-)NCBI
mRatBN7.25153,883,945 - 153,913,766 (-)NCBI
Rnor_6.05160,122,467 - 160,156,209 (-)NCBI
Rnor_5.05163,841,377 - 163,867,441 (-)NCBI
RGSC_v3.45160,468,558 - 160,495,015 (-)RGD
Celera5152,241,216 - 152,267,207 (-)RGD
Sequence:
RefSeq Acc Id: NM_001399241   ⟹   NP_001386170
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85159,167,004 - 159,196,816 (-)NCBI
mRatBN7.25153,883,945 - 153,913,766 (-)NCBI
RefSeq Acc Id: NM_001399242   ⟹   NP_001386171
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85159,167,007 - 159,196,816 (-)NCBI
mRatBN7.25153,883,948 - 153,913,766 (-)NCBI
RefSeq Acc Id: XM_008764273   ⟹   XP_008762495
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85159,167,007 - 159,195,612 (-)NCBI
mRatBN7.25153,883,946 - 153,912,558 (-)NCBI
Rnor_6.05160,122,466 - 160,155,015 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008764274   ⟹   XP_008762496
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85159,167,007 - 159,196,827 (-)NCBI
mRatBN7.25153,883,948 - 153,913,775 (-)NCBI
Rnor_6.05160,122,466 - 160,156,190 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008764276   ⟹   XP_008762498
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85159,167,007 - 159,198,578 (-)NCBI
mRatBN7.25153,883,946 - 153,915,512 (-)NCBI
Rnor_6.05160,122,466 - 160,158,921 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039110428   ⟹   XP_038966356
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85159,167,007 - 159,196,602 (-)NCBI
mRatBN7.25153,883,946 - 153,913,616 (-)NCBI
RefSeq Acc Id: XM_039110429   ⟹   XP_038966357
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85159,167,007 - 159,196,936 (-)NCBI
mRatBN7.25153,883,946 - 153,913,886 (-)NCBI
RefSeq Acc Id: XM_039110430   ⟹   XP_038966358
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85159,167,007 - 159,198,573 (-)NCBI
mRatBN7.25153,883,948 - 153,915,524 (-)NCBI
RefSeq Acc Id: NP_001007555   ⟸   NM_001007554
- Peptide Label: isoform 2
- UniProtKB: Q5U1Y3 (UniProtKB/TrEMBL),   F7FP13 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008762498   ⟸   XM_008764276
- Peptide Label: isoform X4
- UniProtKB: A0A0G2K995 (UniProtKB/TrEMBL),   A6ITU3 (UniProtKB/TrEMBL),   F7FP13 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008762496   ⟸   XM_008764274
- Peptide Label: isoform X3
- UniProtKB: F7FP13 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008762495   ⟸   XM_008764273
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000040868   ⟸   ENSRNOT00000045237
Ensembl Acc Id: ENSRNOP00000074912   ⟸   ENSRNOT00000089345
RefSeq Acc Id: XP_038966357   ⟸   XM_039110429
- Peptide Label: isoform X4
- UniProtKB: A0A0G2K995 (UniProtKB/TrEMBL),   A6ITU3 (UniProtKB/TrEMBL),   F7FP13 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038966356   ⟸   XM_039110428
- Peptide Label: isoform X2
- UniProtKB: F7FP13 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038966358   ⟸   XM_039110430
- Peptide Label: isoform X4
- UniProtKB: A0A0G2K995 (UniProtKB/TrEMBL),   A6ITU3 (UniProtKB/TrEMBL),   F7FP13 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001386170   ⟸   NM_001399241
- Peptide Label: isoform 1
- UniProtKB: A0A0G2K995 (UniProtKB/TrEMBL),   A6ITU3 (UniProtKB/TrEMBL),   F7FP13 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001386171   ⟸   NM_001399242
- Peptide Label: isoform 1
- UniProtKB: A0A0G2K995 (UniProtKB/TrEMBL),   A6ITU3 (UniProtKB/TrEMBL),   F7FP13 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000102131   ⟸   ENSRNOT00000148404
Ensembl Acc Id: ENSRNOP00000099565   ⟸   ENSRNOT00000133282
Protein Domains
LIM zinc-binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K995-F1-model_v2 AlphaFold A0A0G2K995 1-376 view protein structure
AF-F1LQ48-F1-model_v2 AlphaFold F1LQ48 1-623 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694228
Promoter ID:EPDNEW_R4752
Type:multiple initiation site
Name:Fblim1_1
Description:filamin binding LIM protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R4753  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05160,156,202 - 160,156,262EPDNEW
RGD ID:13694239
Promoter ID:EPDNEW_R4753
Type:initiation region
Name:Fblim1_2
Description:filamin binding LIM protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R4752  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05160,158,396 - 160,158,456EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359551 AgrOrtholog
BioCyc Gene G2FUF-39338 BioCyc
Ensembl Genes ENSRNOG00000011774 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000045237 ENTREZGENE
  ENSRNOT00000045237.4 UniProtKB/TrEMBL
  ENSRNOT00000089345 ENTREZGENE
  ENSRNOT00000089345.2 UniProtKB/TrEMBL
  ENSRNOT00000133282 ENTREZGENE
  ENSRNOT00000148404 ENTREZGENE
Gene3D-CATH Cysteine Rich Protein UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7303205 IMAGE-MGC_LOAD
InterPro Znf_LIM UniProtKB/TrEMBL
KEGG Report rno:362650 UniProtKB/TrEMBL
MGC_CLONE MGC:105665 IMAGE-MGC_LOAD
NCBI Gene 362650 ENTREZGENE
PANTHER FILAMIN-BINDING LIM PROTEIN 1 UniProtKB/TrEMBL
  ZYX102 PROTEIN UniProtKB/TrEMBL
Pfam LIM UniProtKB/TrEMBL
PhenoGen Fblim1 PhenoGen
PROSITE LIM_DOMAIN_1 UniProtKB/TrEMBL
  LIM_DOMAIN_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000011774 RatGTEx
SMART LIM UniProtKB/TrEMBL
Superfamily-SCOP Glucocorticoid receptor-like (DNA-binding domain) UniProtKB/TrEMBL
UniProt A0A0G2K995 ENTREZGENE, UniProtKB/TrEMBL
  A6ITU3 ENTREZGENE, UniProtKB/TrEMBL
  F1LQ48 ENTREZGENE
  F7FP13 ENTREZGENE, UniProtKB/TrEMBL
  Q5U1Y3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Fblim1  filamin binding LIM protein 1  Cal  CSX-associated LIM  Symbol and Name updated 1299863 APPROVED
2005-07-29 Cal  CSX-associated LIM      Symbol and Name status set to provisional 70820 PROVISIONAL