Pms1 (PMS1 homolog 1, mismatch repair system component) - Rat Genome Database

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Gene: Pms1 (PMS1 homolog 1, mismatch repair system component) Rattus norvegicus
Analyze
Symbol: Pms1
Name: PMS1 homolog 1, mismatch repair system component
RGD ID: 1359511
Description: Predicted to enable ATP hydrolysis activity and enzyme binding activity. Involved in response to xenobiotic stimulus. Predicted to be located in nucleus. Predicted to be part of MutLalpha complex. Human ortholog(s) of this gene implicated in Lynch syndrome; dermatomyositis; pancreatic ductal carcinoma; and polymyositis. Orthologous to human PMS1 (PMS1 homolog 1, mismatch repair system component); PARTICIPATES IN altered mismatch repair pathway; colorectal cancer pathway; mismatch repair pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4-hydroperoxycyclophosphamide; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC100911809; MGC72584; PMS1 postmeiotic segregation increased 1; PMS1 postmeiotic segregation increased 1 (S. cerevisiae); PMS1 protein homolog 1; postmeiotic segregation increased 1; postmeiotic segregation increased 1 (S. cerevisiae); similar to postmeiotic segregation increased 1; uncharacterized LOC100911809
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8955,721,393 - 55,832,225 (+)NCBIGRCr8
mRatBN7.2948,229,403 - 48,340,237 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl948,253,410 - 48,340,237 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx956,789,682 - 56,875,049 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0961,912,501 - 61,997,868 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0960,208,491 - 60,293,858 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0953,120,656 - 53,206,520 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl953,120,656 - 53,206,516 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0952,784,772 - 52,871,014 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4945,203,344 - 45,292,624 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1945,204,757 - 45,294,034 (+)NCBI
Celera945,919,538 - 46,005,758 (+)NCBICelera
Cytogenetic Map9q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4-hydroperoxycyclophosphamide  (EXP)
acrolein  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
asbestos  (ISO)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cadmium dichloride  (EXP,ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
CU-O LINKAGE  (ISO)
cyclophosphamide  (EXP)
cyclosporin A  (ISO)
cypermethrin  (ISO)
dexamethasone  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
elemental selenium  (ISO)
ethyl methanesulfonate  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
furan  (EXP)
gentamycin  (EXP)
indole-3-methanol  (EXP)
indometacin  (ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
methotrexate  (ISO)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
O-methyleugenol  (EXP)
ochratoxin A  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
resveratrol  (EXP,ISO)
SB 431542  (ISO)
selenium atom  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
succimer  (ISO)
temozolomide  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
trovafloxacin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vincristine  (ISO)
vitamin E  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. DNA mismatch repair defects: role in colorectal carcinogenesis. Jacob S and Praz F, Biochimie. 2002 Jan;84(1):27-47.
3. Mechanisms and functions of DNA mismatch repair. Li GM Cell Res. 2008 Jan;18(1):85-98.
4. Mutations of two PMS homologues in hereditary nonpolyposis colon cancer. Nicolaides NC, etal., Nature. 1994 Sep 1;371(6492):75-80.
5. Immune responses to DNA mismatch repair enzymes hMSH2 and hPMS1 in patients with pancreatic cancer, dermatomyositis and polymyositis. Okada T, etal., Int J Cancer. 2005 Oct 10;116(6):925-33.
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
11. Expression of base excision, mismatch, and recombination repair genes in the organogenesis-stage rat conceptus and effects of exposure to a genotoxic teratogen, 4-hydroperoxycyclophosphamide. Vinson RK and Hales BF, Teratology. 2001 Dec;64(6):283-91.
Additional References at PubMed
PMID:9500552   PMID:26300262  


Genomics

Comparative Map Data
Pms1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8955,721,393 - 55,832,225 (+)NCBIGRCr8
mRatBN7.2948,229,403 - 48,340,237 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl948,253,410 - 48,340,237 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx956,789,682 - 56,875,049 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0961,912,501 - 61,997,868 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0960,208,491 - 60,293,858 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0953,120,656 - 53,206,520 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl953,120,656 - 53,206,516 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0952,784,772 - 52,871,014 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4945,203,344 - 45,292,624 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1945,204,757 - 45,294,034 (+)NCBI
Celera945,919,538 - 46,005,758 (+)NCBICelera
Cytogenetic Map9q22NCBI
PMS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382189,784,450 - 189,877,629 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2189,784,085 - 189,877,629 (+)EnsemblGRCh38hg38GRCh38
GRCh372190,649,176 - 190,742,355 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362190,357,355 - 190,450,600 (+)NCBINCBI36Build 36hg18NCBI36
Build 342190,474,615 - 190,567,860NCBI
Celera2184,243,739 - 184,337,288 (+)NCBICelera
Cytogenetic Map2q32.2NCBI
HuRef2182,508,462 - 182,602,272 (+)NCBIHuRef
CHM1_12190,654,694 - 190,748,309 (+)NCBICHM1_1
T2T-CHM13v2.02190,273,733 - 190,366,996 (+)NCBIT2T-CHM13v2.0
Pms1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39153,225,794 - 53,336,190 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl153,228,346 - 53,336,177 (-)EnsemblGRCm39 Ensembl
GRCm38153,189,187 - 53,297,031 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl153,189,187 - 53,297,018 (-)EnsemblGRCm38mm10GRCm38
MGSCv37153,246,031 - 53,353,840 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36153,133,732 - 53,241,541 (-)NCBIMGSCv36mm8
Celera153,728,483 - 53,836,401 (-)NCBICelera
Cytogenetic Map1C1.1NCBI
cM Map126.99NCBI
Pms1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554039,022,078 - 9,100,442 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554039,021,488 - 9,100,442 (-)NCBIChiLan1.0ChiLan1.0
PMS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21392,475,954 - 92,566,780 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B92,490,937 - 92,581,763 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B77,090,215 - 77,180,724 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B195,010,233 - 195,100,492 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B195,010,233 - 195,100,492 (+)Ensemblpanpan1.1panPan2
PMS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.137502,752 - 609,640 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl37502,747 - 790,904 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha371,475,758 - 1,583,050 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.037395,761 - 503,686 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl37395,722 - 503,685 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.137406,588 - 513,890 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.037375,065 - 482,126 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.037403,027 - 510,344 (+)NCBIUU_Cfam_GSD_1.0
Pms1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303148,621,339 - 148,718,585 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365068,119,494 - 8,197,768 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365068,118,816 - 8,197,040 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PMS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1594,351,630 - 94,476,506 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11594,351,603 - 94,476,505 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215105,412,685 - 105,513,299 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PMS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11075,305,129 - 75,392,193 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1075,311,887 - 75,392,590 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040124,084,971 - 124,175,531 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Pms1
821 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:85
Count of miRNA genes:76
Interacting mature miRNAs:80
Transcripts:ENSRNOT00000043714
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7411571Bw138Body weight QTL 13814.30.001body mass (VT:0001259)body weight gain (CMO:0000420)93253550577535505Rat
1300180Bw14Body weight QTL 143.776body mass (VT:0001259)body weight (CMO:0000012)92375402461381613Rat
11353957Bmd92Bone mineral density QTL 920.01tibia mineral mass (VT:1000283)volumetric bone mineral density (CMO:0001553)94611419991114199Rat
631680Cm11Cardiac mass QTL 113.10.00089heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)92043051965430519Rat
70218Cm28Cardiac mass QTL 288.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)92526804479271759Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)925268044114175309Rat
7207805Bmd88Bone mineral density QTL 884femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)92375402458157242Rat
631643Bp120Blood pressure QTL 12030.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)92207120067071200Rat
12879506Pur33Proteinuria QTL 33urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)94464992189649921Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)925661188100929786Rat
10058949Gmadr5Adrenal mass QTL 520.014adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)94279151387976209Rat
9589133Insul26Insulin level QTL 2617.960.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)9895256053952560Rat
631211Bw4Body weight QTL45.31retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)9510982650109826Rat
61352Bp34Blood pressure QTL 345arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94249534379271511Rat
6903937Bp356Blood pressure QTL 3560.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94790220852283252Rat
7411609Foco16Food consumption QTL 1625.60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9895256053952560Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)93696235992058970Rat
1598834Memor11Memory QTL 112.5exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)93696235977814038Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92207116986369743Rat
7207814Bmd91Bone mineral density QTL 913.5femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)92375414483851531Rat
6903941Pur31Proteinuria QTL 310.036urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)94019418885194188Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)93696235995410867Rat
11353949Bp393Blood pressure QTL 393arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94019418885194188Rat
11353951Bp394Blood pressure QTL 394arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94464992189649921Rat
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
11353947Bp392Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)9728325252283252Rat
1331757Cdexp1CD45RC expression in CD8 T cells QTL 14.3CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)9102453767509080Rat
7411656Foco26Food consumption QTL 269.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)93253550577535505Rat
1641894Alcrsp12Alcohol response QTL 12response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)92746863972468639Rat
1598823Memor16Memory QTL 161.9exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)92213332249968732Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000043714   ⟹   ENSRNOP00000047584
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl948,253,410 - 48,340,237 (+)Ensembl
Rnor_6.0 Ensembl953,120,656 - 53,206,516 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000096508   ⟹   ENSRNOP00000092976
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl948,253,410 - 48,340,237 (+)Ensembl
RefSeq Acc Id: NM_001009535   ⟹   NP_001009535
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8955,745,388 - 55,832,225 (+)NCBI
mRatBN7.2948,253,398 - 48,340,237 (+)NCBI
Rnor_6.0953,120,656 - 53,206,520 (+)NCBI
Rnor_5.0952,784,772 - 52,871,014 (+)NCBI
RGSC_v3.4945,203,344 - 45,292,624 (+)RGD
Celera945,919,538 - 46,005,758 (+)RGD
Sequence:
RefSeq Acc Id: XM_039084041   ⟹   XP_038939969
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8955,721,393 - 55,832,225 (+)NCBI
mRatBN7.2948,229,403 - 48,340,237 (+)NCBI
RefSeq Acc Id: XM_039084042   ⟹   XP_038939970
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8955,745,355 - 55,832,225 (+)NCBI
mRatBN7.2948,253,338 - 48,340,237 (+)NCBI
RefSeq Acc Id: XM_039084043   ⟹   XP_038939971
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8955,745,344 - 55,832,225 (+)NCBI
mRatBN7.2948,253,338 - 48,340,237 (+)NCBI
RefSeq Acc Id: XM_039084044   ⟹   XP_038939972
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8955,745,304 - 55,832,225 (+)NCBI
mRatBN7.2948,253,310 - 48,340,237 (+)NCBI
RefSeq Acc Id: XM_039084045   ⟹   XP_038939973
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8955,751,299 - 55,832,225 (+)NCBI
mRatBN7.2948,259,307 - 48,340,237 (+)NCBI
RefSeq Acc Id: XM_039084046   ⟹   XP_038939974
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8955,804,479 - 55,832,225 (+)NCBI
mRatBN7.2948,312,490 - 48,340,237 (+)NCBI
RefSeq Acc Id: XR_010054623
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8955,745,309 - 55,807,462 (+)NCBI
RefSeq Acc Id: NP_001009535   ⟸   NM_001009535
- UniProtKB: Q6P7D0 (UniProtKB/TrEMBL),   A0A8I6AGZ9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000047584   ⟸   ENSRNOT00000043714
RefSeq Acc Id: XP_038939969   ⟸   XM_039084041
- Peptide Label: isoform X1
- UniProtKB: D4A651 (UniProtKB/TrEMBL),   A0A8I6AGZ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939972   ⟸   XM_039084044
- Peptide Label: isoform X1
- UniProtKB: D4A651 (UniProtKB/TrEMBL),   A0A8I6AGZ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939970   ⟸   XM_039084042
- Peptide Label: isoform X1
- UniProtKB: D4A651 (UniProtKB/TrEMBL),   A0A8I6AGZ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939971   ⟸   XM_039084043
- Peptide Label: isoform X1
- UniProtKB: D4A651 (UniProtKB/TrEMBL),   A0A8I6AGZ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939973   ⟸   XM_039084045
- Peptide Label: isoform X1
- UniProtKB: D4A651 (UniProtKB/TrEMBL),   A0A8I6AGZ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939974   ⟸   XM_039084046
- Peptide Label: isoform X2
- UniProtKB: A6INU7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000092976   ⟸   ENSRNOT00000096508
Protein Domains
HMG box

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696651
Promoter ID:EPDNEW_R7175
Type:initiation region
Name:Pms1_1
Description:PMS1 homolog 1, mismatch repair system component
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0953,120,646 - 53,120,706EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359511 AgrOrtholog
BioCyc Gene G2FUF-27628 BioCyc
Ensembl Genes ENSRNOG00000004076 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000043714.5 UniProtKB/TrEMBL
  ENSRNOT00000096508.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.30.10 UniProtKB/TrEMBL
  3.30.230.10 UniProtKB/TrEMBL
  3.30.565.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:5598508 IMAGE-MGC_LOAD
InterPro DNA_mismatch_repair UniProtKB/TrEMBL
  DNA_mismatch_repair_C UniProtKB/TrEMBL
  DNA_mismatch_repair_CS UniProtKB/TrEMBL
  HATPase_C_sf UniProtKB/TrEMBL
  HMG_box_dom_sf UniProtKB/TrEMBL
  HMG_superfamily UniProtKB/TrEMBL
  MutL/Mlh/Pms UniProtKB/TrEMBL
  Ribosomal_S5_D2-typ_fold UniProtKB/TrEMBL
  Ribosomal_S5_D2-typ_fold_subgr UniProtKB/TrEMBL
KEGG Report rno:494322 UniProtKB/TrEMBL
MGC_CLONE MGC:72584 IMAGE-MGC_LOAD
NCBI Gene 494322 ENTREZGENE
PANTHER PMS1 PROTEIN HOMOLOG 1 UniProtKB/TrEMBL
  PTHR10073 UniProtKB/TrEMBL
Pfam DNA_mis_repair UniProtKB/TrEMBL
  HATPase_c_3 UniProtKB/TrEMBL
  HMG_box UniProtKB/TrEMBL
PhenoGen Pms1 PhenoGen
PROSITE DNA_MISMATCH_REPAIR_1 UniProtKB/TrEMBL
  HMG_BOX_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004076 RatGTEx
SMART DNA_mis_repair UniProtKB/TrEMBL
  HMG UniProtKB/TrEMBL
Superfamily-SCOP ATP_bd_ATPase UniProtKB/TrEMBL
  HMG-box UniProtKB/TrEMBL
  Ribosomal_S5_D2-typ_fold UniProtKB/TrEMBL
UniProt A0A8I6AGZ9 ENTREZGENE, UniProtKB/TrEMBL
  A6INU7 ENTREZGENE, UniProtKB/TrEMBL
  D4A651 ENTREZGENE, UniProtKB/TrEMBL
  Q6P7D0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Pms1  PMS1 homolog 1, mismatch repair system component  LOC100911809  uncharacterized LOC100911809  Data merged from RGD:6490463 737654 PROVISIONAL
2016-03-16 Pms1  PMS1 homolog 1, mismatch repair system component  Pms1  postmeiotic segregation increased 1 (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-05 LOC100911809  uncharacterized LOC100911809      Symbol and Name status set to provisional 70820 PROVISIONAL
2010-05-13 Pms1  postmeiotic segregation increased 1 (S. cerevisiae)  Pms1  PMS1 postmeiotic segregation increased 1 (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-09 Pms1  PMS1 postmeiotic segregation increased 1 (S. cerevisiae)  Pms1  postmeiotic segregation increased 1 (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-06 Pms1  postmeiotic segregation increased 1 (S. cerevisiae)  MGC72584  similar to postmeiotic segregation increased 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-29 MGC72584  similar to postmeiotic segregation increased 1      Symbol and Name status set to provisional 70820 PROVISIONAL