Rpl17l2 (ribosomal protein L17-like 2) - Rat Genome Database

Send us a Message

Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Rpl17l2 (ribosomal protein L17-like 2) Rattus norvegicus
No known orthologs.
Symbol: Rpl17l2 (Ensembl: RGD1359290)
Name: ribosomal protein L17-like 2 (Ensembl:Ribosomal_L22 domain containing protein RGD1359290)
RGD ID: 1359290
Description: Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Predicted to be part of cytosolic large ribosomal subunit; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 60S ribosomal protein L17; Ac2-210; LOC360649; RGD1359290; Ribosomal_L22 domain containing protein RGD1359290; similar to Ac2-210
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
mRatBN7.21092,373,735 - 92,374,368 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1092,373,775 - 92,389,465 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01095,634,706 - 95,657,977 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1095,642,640 - 95,657,977 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01095,369,356 - 95,392,627 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41096,796,306 - 96,819,928 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11096,810,675 - 96,834,298 (+)NCBI
Celera1091,030,612 - 91,054,228 (+)NCBICelera
Cytogenetic Map10q32.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function


References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions



Variants in Rpl17l2
7 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:42
Count of miRNA genes:40
Interacting mature miRNAs:42
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3191609953Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
61419Cia11Collagen induced arthritis QTL 115.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)33035677398535386Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)333703347104104347Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)341874578104104347Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)343827364121056321Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
631665Bw8Body weight QTL 85.5body mass (VT:0001259)body weight (CMO:0000012)350437042119183768Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)350437504115638231Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)353184593115665732Rat
731180Bp152Blood pressure QTL 1520.03arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)35378111291609953Rat
731180Bp152Blood pressure QTL 1520.03arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)35378111291609953Rat
731180Bp152Blood pressure QTL 1520.03arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35378111291609953Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)361017749121056321Rat
1582210Bw71Body weight QTL 713.30.0012body mass (VT:0001259)body weight (CMO:0000012)364655305115665732Rat
1582221Kidm30Kidney mass QTL 303.50.0008kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)364655305115665732Rat
12879848Bw181Body weght QTL 1810.015body mass (VT:0001259)body weight (CMO:0000012)370348525121056321Rat
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)370653097121056321Rat
1600376Arunc5Aerobic running capacity QTL 50.21exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)373376539118376539Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)378196190146592722Rat
2302273Gluco35Glucose level QTL 355.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)380800231114297550Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)389772419134772419Rat

Markers in Region
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21092,369,364 - 92,369,470 (+)MAPPERmRatBN7.2
Rnor_6.01095,638,234 - 95,638,337NCBIRnor6.0
Rnor_5.01095,372,884 - 95,372,987UniSTSRnor5.0
RGSC_v3.41096,799,833 - 96,799,937RGDRGSC3.4
RGSC_v3.41096,799,834 - 96,799,937UniSTSRGSC3.4
RGSC_v3.11096,814,203 - 96,814,307RGD
Celera1091,034,140 - 91,034,243UniSTS
RH 3.4 Map101021.3UniSTS
RH 3.4 Map101021.3RGD
RH 2.0 Map101120.3RGD
SHRSP x BN Map1073.41RGD
FHH x ACI Map1076.95RGD
Cytogenetic Map10q32.1UniSTS


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
Medium 3 5 31 19 19 19 1 2 34 14 34 10 1
Low 38 26 22 22 7 9 40 21 7 1 7
Below cutoff


RefSeq Acc Id: ENSRNOT00000029782   ⟹   ENSRNOP00000034767
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1092,373,775 - 92,389,465 (+)Ensembl
Rnor_6.0 Ensembl1095,642,640 - 95,657,977 (+)Ensembl
RefSeq Acc Id: XM_056984719   ⟹   XP_056840699
Rat AssemblyChrPosition (strand)Source
mRatBN7.21092,373,735 - 92,374,368 (+)NCBI
Protein Sequences
Protein RefSeqs XP_056840699 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAP86270 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: ENSRNOP00000034767   ⟸   ENSRNOT00000029782
RefSeq Acc Id: XP_056840699   ⟸   XM_056984719
- UniProtKB: A0A0H2UHQ1 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q7TPJ7-F1-model_v2 AlphaFold Q7TPJ7 1-220 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359290 AgrOrtholog
BioCyc Gene G2FUF-22900 BioCyc
Ensembl Genes ENSRNOG00000018680 UniProtKB/TrEMBL
  ENSRNOG00000027271 Ensembl, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000025217 UniProtKB/TrEMBL
  ENSRNOP00000034767.3 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000025217 UniProtKB/TrEMBL
  ENSRNOT00000029782.4 UniProtKB/TrEMBL
Gene3D-CATH 3.90.470.10 UniProtKB/TrEMBL
InterPro Ribosomal_L22 UniProtKB/TrEMBL
  Ribosomal_L22/L17_CS UniProtKB/TrEMBL
  Ribosomal_L22/L17_euk/arc UniProtKB/TrEMBL
  Ribosomal_L22/L17_sf UniProtKB/TrEMBL
KEGG Report rno:360649 UniProtKB/TrEMBL
  Ribosomal_L22/17 UniProtKB/TrEMBL
Pfam Ribosomal_L22 UniProtKB/TrEMBL
PhenoGen Rpl17l2 PhenoGen
Superfamily-SCOP Ribosomal_L22 UniProtKB/TrEMBL

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Rpl17l2  ribosomal protein L17-like 2  RGD1359290  Ribosomal_L22 domain containing protein RGD1359290  Symbol and Name Changed 1299863 APPROVED
2005-11-17 RGD1359290  Ribosomal_L22 domain containing protein RGD1359290  LOC360649  similar to Ac2-210  Symbol and Name updated 1299863 APPROVED
2005-07-29 LOC360649  similar to Ac2-210      Symbol and Name status set to provisional 70820 PROVISIONAL