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Gene: Mink1 (misshapen-like kinase 1) Rattus norvegicus
Symbol: Mink1
Name: misshapen-like kinase 1
Description: Predicted to have ATP binding activity and protein serine/threonine kinase activity. Involved in several processes, including dendrite morphogenesis; neuron cellular homeostasis; and regulation of AMPA receptor activity. Predicted to localize to Golgi apparatus. Orthologous to human MINK1 (misshapen like kinase 1); INTERACTS WITH bisphenol A; diuron; 1,2-dimethylhydrazine (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: GCK family kinase MiNK; LOC303259; MAPK/ERK kinase kinase kinase 6; MEK kinase kinase 6; MEKKK 6; misshapen-like kinase 1 (zebrafish); misshapen/NIK-related kinase; mitogen-activated protein kinase kinase kinase kinase 6; similar to Map4k6-pending protein
Homo sapiens (human) : MINK1 (misshapen like kinase 1)  HGNC  Alliance
Mus musculus (house mouse) : Mink1 (misshapen-like kinase 1 (zebrafish))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mink1 (misshapen like kinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MINK1 (misshapen like kinase 1)
Canis lupus familiaris (dog) : MINK1 (misshapen like kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mink1 (misshapen like kinase 1)
Sus scrofa (pig) : MINK1 (misshapen like kinase 1)
Chlorocebus sabaeus (African green monkey) : MINK1 (misshapen like kinase 1)
Heterocephalus glaber (naked mole-rat) : Mink1 (misshapen like kinase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01057,185,310 - 57,238,531 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1057,185,347 - 57,238,531 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01056,930,810 - 56,984,074 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41057,443,253 - 57,496,763 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11057,507,528 - 57,510,382 (+)NCBI
Celera1054,424,066 - 54,476,447 (+)NCBICelera
Cytogenetic Map10q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Mink1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1359135
Created: 2005-07-29
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.