PCTP (phosphatidylcholine transfer protein) - Rat Genome Database

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Gene: PCTP (phosphatidylcholine transfer protein) Homo sapiens
Analyze
Symbol: PCTP
Name: phosphatidylcholine transfer protein
RGD ID: 1353620
HGNC Page HGNC:8752
Description: Enables phosphatidylcholine binding activity and phosphatidylcholine transporter activity. Involved in phospholipid transport. Predicted to be located in cytosol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: PC-TP; StAR-related lipid transfer (START) domain containing 2; stAR-related lipid transfer protein 2; STARD2; START domain containing 2; START domain-containing protein 2
RGD Orthologs
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381755,751,051 - 55,852,715 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1755,751,051 - 55,842,830 (+)EnsemblGRCh38hg38GRCh38
GRCh371753,828,412 - 53,900,498 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361751,183,355 - 51,209,747 (+)NCBINCBI36Build 36hg18NCBI36
Build 341751,183,448 - 51,209,733NCBI
Celera1750,290,127 - 50,316,517 (+)NCBICelera
Cytogenetic Map17q22NCBI
HuRef1749,187,946 - 49,214,609 (+)NCBIHuRef
CHM1_11753,893,255 - 53,919,657 (+)NCBICHM1_1
T2T-CHM13v2.01756,627,170 - 56,721,145 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(1->4)-beta-D-glucan  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dinitrotoluene  (ISO)
3-chloropropane-1,2-diol  (ISO)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxyphenyl retinamide  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (ISO)
6-propyl-2-thiouracil  (ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (EXP)
amiodarone  (ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
benzbromarone  (ISO)
benzo[a]pyrene  (EXP)
benzo[b]fluoranthene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (ISO)
buspirone  (ISO)
cadmium atom  (EXP)
cadmium dichloride  (EXP)
calcitriol  (EXP)
capsaicin  (EXP)
CGP 52608  (EXP)
choline  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (EXP)
clofibrate  (EXP,ISO)
clofibric acid  (ISO)
copper(II) sulfate  (EXP)
coumestrol  (EXP)
cyclosporin A  (EXP)
dichloroacetic acid  (ISO)
dicrotophos  (EXP)
doxorubicin  (EXP)
fipronil  (ISO)
folic acid  (ISO)
furan  (ISO)
gentamycin  (ISO)
glycine betaine  (ISO)
inulin  (ISO)
iron atom  (ISO)
iron(0)  (ISO)
isotretinoin  (EXP)
ketoconazole  (ISO)
L-ethionine  (ISO)
L-methionine  (ISO)
leflunomide  (ISO)
lithocholic acid  (ISO)
methapyrilene  (ISO)
methimazole  (ISO)
N-nitrosodiethylamine  (ISO)
nefazodone  (ISO)
nickel atom  (EXP)
nickel dichloride  (ISO)
nitrofen  (ISO)
omeprazole  (ISO)
oxaliplatin  (ISO)
paracetamol  (ISO)
pentachlorophenol  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
permethrin  (ISO)
phenobarbital  (EXP,ISO)
pirinixic acid  (ISO)
pravastatin  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
raloxifene  (EXP)
silver atom  (ISO)
silver(0)  (ISO)
sodium dodecyl sulfate  (EXP)
Soman  (ISO)
sulfadimethoxine  (ISO)
tamoxifen  (EXP)
Tesaglitazar  (ISO)
testosterone  (EXP,ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (ISO)
tetracycline  (ISO)
thioacetamide  (ISO)
topotecan  (ISO)
trichloroethene  (ISO)
triphenyl phosphate  (ISO)
trovafloxacin  (ISO)
valproic acid  (EXP,ISO)
zaragozic acid A  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
cytosol  (NAS,TAS)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10500206   PMID:10542325   PMID:11983415   PMID:12055623   PMID:12477932   PMID:15489334   PMID:17266964   PMID:17704541   PMID:18676680   PMID:18976975   PMID:19170196   PMID:19502644  
PMID:19625176   PMID:19692168   PMID:19913121   PMID:21873635   PMID:22021425   PMID:24216752   PMID:25416956   PMID:26585945   PMID:28251237   PMID:28514442   PMID:29955039   PMID:33770537  
PMID:33961781   PMID:35831314  


Genomics

Comparative Map Data
PCTP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381755,751,051 - 55,852,715 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1755,751,051 - 55,842,830 (+)EnsemblGRCh38hg38GRCh38
GRCh371753,828,412 - 53,900,498 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361751,183,355 - 51,209,747 (+)NCBINCBI36Build 36hg18NCBI36
Build 341751,183,448 - 51,209,733NCBI
Celera1750,290,127 - 50,316,517 (+)NCBICelera
Cytogenetic Map17q22NCBI
HuRef1749,187,946 - 49,214,609 (+)NCBIHuRef
CHM1_11753,893,255 - 53,919,657 (+)NCBICHM1_1
T2T-CHM13v2.01756,627,170 - 56,721,145 (+)NCBIT2T-CHM13v2.0
Pctp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391189,873,370 - 89,893,720 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1189,873,491 - 89,893,720 (-)EnsemblGRCm39 Ensembl
GRCm381189,982,544 - 90,002,894 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1189,982,665 - 90,002,894 (-)EnsemblGRCm38mm10GRCm38
MGSCv371189,844,731 - 89,864,208 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361189,800,687 - 89,818,955 (-)NCBIMGSCv36mm8
Celera1199,590,697 - 99,613,489 (-)NCBICelera
Cytogenetic Map11CNCBI
cM Map1154.7NCBI
Pctp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81075,305,999 - 75,351,919 (-)NCBIGRCr8
mRatBN7.21074,808,887 - 74,856,260 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1074,808,887 - 74,849,867 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1079,424,875 - 79,465,710 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01078,929,821 - 78,970,657 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01074,404,137 - 74,444,999 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01077,491,445 - 77,537,268 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1077,491,454 - 77,512,032 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01077,353,593 - 77,394,532 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41078,400,328 - 78,420,774 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11078,414,697 - 78,435,144 (-)NCBI
Celera1073,699,943 - 73,741,523 (-)NCBICelera
RH 3.4 Map10707.0RGD
Cytogenetic Map10q26NCBI
PCTP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21971,930,254 - 72,024,574 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11776,740,464 - 76,834,711 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01749,834,065 - 49,928,134 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11754,696,803 - 54,770,248 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1754,696,803 - 54,770,244 (+)Ensemblpanpan1.1panPan2
PCTP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1930,725,209 - 30,749,891 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl930,724,157 - 30,853,803 (+)EnsemblCanFam3.1canFam3CanFam3.1
Pctp
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560230,146,046 - 30,172,180 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364906,902,957 - 6,929,098 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364906,902,959 - 6,929,051 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PCTP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11232,043,841 - 32,089,977 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
PCTP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11637,558,590 - 37,638,721 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1637,614,222 - 37,638,120 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660778,404,683 - 8,475,624 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pctp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479510,972,933 - 10,998,944 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479510,972,998 - 11,000,163 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PCTP
13 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 17q21.33-24.2(chr17:36449220-68170214)x3 copy number gain See cases [RCV000050957] Chr17:36449220..68170214 [GRCh38]
Chr17:48563237..65936105 [GRCh37]
Chr17:45918236..63677950 [NCBI36]
Chr17:17q21.33-24.2
pathogenic
GRCh38/hg38 17q23.2-25.3(chr17:36449220-83086677)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052483]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052483]|See cases [RCV000052483] Chr17:36449220..83086677 [GRCh38]
Chr17:58617905..81044553 [GRCh37]
Chr17:55972687..78637842 [NCBI36]
Chr17:17q23.2-25.3
pathogenic
GRCh38/hg38 17q21.33-22(chr17:49974533-56807609)x1 copy number loss See cases [RCV000053433] Chr17:49974533..56807609 [GRCh38]
Chr17:48051897..54884970 [GRCh37]
Chr17:45406896..52239969 [NCBI36]
Chr17:17q21.33-22
pathogenic
NM_001102402.2(PCTP):c.-75-7424T>A single nucleotide variant Lung cancer [RCV000100554] Chr17:55759911 [GRCh38]
Chr17:53837272 [GRCh37]
Chr17:17q22
uncertain significance
GRCh38/hg38 17q23.1-25.1(chr17:36449220-75053130)x3 copy number gain See cases [RCV000137437] Chr17:36449220..75053130 [GRCh38]
Chr17:57595736..73049225 [GRCh37]
Chr17:54950518..70560820 [NCBI36]
Chr17:17q23.1-25.1
pathogenic
GRCh37/hg19 17q22(chr17:52189051-57477162)x3 copy number gain See cases [RCV000448801] Chr17:52189051..57477162 [GRCh37]
Chr17:17q22
pathogenic
GRCh37/hg19 17q21.33-23.2(chr17:49076980-58740945)x3 copy number gain See cases [RCV000448805] Chr17:49076980..58740945 [GRCh37]
Chr17:17q21.33-23.2
pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:526-81041938) copy number gain See cases [RCV000511439] Chr17:526..81041938 [GRCh37]
Chr17:17p13.3-q25.3
pathogenic
NM_021213.4(PCTP):c.494G>C (p.Gly165Ala) single nucleotide variant Inborn genetic diseases [RCV003259771] Chr17:55773878 [GRCh38]
Chr17:53851239 [GRCh37]
Chr17:17q22
uncertain significance
GRCh37/hg19 17q21.31-25.3(chr17:42580684-81085615)x3 copy number gain See cases [RCV000447823] Chr17:42580684..81085615 [GRCh37]
Chr17:17q21.31-25.3
pathogenic
NM_021213.4(PCTP):c.452G>A (p.Arg151Gln) single nucleotide variant Inborn genetic diseases [RCV003293753] Chr17:55773836 [GRCh38]
Chr17:53851197 [GRCh37]
Chr17:17q22
uncertain significance
GRCh37/hg19 17p13.3-q25.3(chr17:526-81041938)x3 copy number gain See cases [RCV000512441] Chr17:526..81041938 [GRCh37]
Chr17:17p13.3-q25.3
pathogenic
GRCh37/hg19 17q22(chr17:53309576-54333707)x1 copy number loss not provided [RCV000683943] Chr17:53309576..54333707 [GRCh37]
Chr17:17q22
uncertain significance
GRCh37/hg19 17p13.3-q25.3(chr17:12344-81057996)x3 copy number gain not provided [RCV000739325] Chr17:12344..81057996 [GRCh37]
Chr17:17p13.3-q25.3
pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:8547-81060040)x3 copy number gain not provided [RCV000739324] Chr17:8547..81060040 [GRCh37]
Chr17:17p13.3-q25.3
pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:7214-81058310)x3 copy number gain not provided [RCV000739320] Chr17:7214..81058310 [GRCh37]
Chr17:17p13.3-q25.3
pathogenic
NM_021213.4(PCTP):c.448A>G (p.Ile150Val) single nucleotide variant Inborn genetic diseases [RCV003266903] Chr17:55773832 [GRCh38]
Chr17:53851193 [GRCh37]
Chr17:17q22
uncertain significance
NM_021213.4(PCTP):c.616G>A (p.Ala206Thr) single nucleotide variant Inborn genetic diseases [RCV002859349] Chr17:55776071 [GRCh38]
Chr17:53853432 [GRCh37]
Chr17:17q22
uncertain significance
NM_021213.4(PCTP):c.451C>T (p.Arg151Trp) single nucleotide variant Inborn genetic diseases [RCV002926231] Chr17:55773835 [GRCh38]
Chr17:53851196 [GRCh37]
Chr17:17q22
uncertain significance
NM_021213.4(PCTP):c.388A>T (p.Ile130Phe) single nucleotide variant Inborn genetic diseases [RCV002739492] Chr17:55773772 [GRCh38]
Chr17:53851133 [GRCh37]
Chr17:17q22
uncertain significance
NM_021213.4(PCTP):c.571G>A (p.Ala191Thr) single nucleotide variant Inborn genetic diseases [RCV002955253] Chr17:55774851 [GRCh38]
Chr17:53852212 [GRCh37]
Chr17:17q22
uncertain significance
NM_021213.4(PCTP):c.23T>C (p.Phe8Ser) single nucleotide variant Inborn genetic diseases [RCV002936975] Chr17:55751126 [GRCh38]
Chr17:53828487 [GRCh37]
Chr17:17q22
uncertain significance
NM_021213.4(PCTP):c.215A>G (p.Tyr72Cys) single nucleotide variant Inborn genetic diseases [RCV002769221] Chr17:55767408 [GRCh38]
Chr17:53844769 [GRCh37]
Chr17:17q22
uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:3569
Count of miRNA genes:860
Interacting mature miRNAs:1011
Transcripts:ENST00000268896, ENST00000325214, ENST00000417982, ENST00000571489, ENST00000572536, ENST00000573500, ENST00000576183, ENST00000576221
Prediction methods:Microtar, Miranda, Pita, Pita,Targetscan, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
STS-W57964  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371753,854,407 - 53,854,653UniSTSGRCh37
Build 361751,209,406 - 51,209,652RGDNCBI36
Celera1750,316,176 - 50,316,422RGD
Cytogenetic Map17q21-q24UniSTS
HuRef1749,214,268 - 49,214,514UniSTS
GeneMap99-GB4 RH Map17363.4UniSTS
RH123437  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371753,854,441 - 53,854,711UniSTSGRCh37
Build 361751,209,440 - 51,209,710RGDNCBI36
Celera1750,316,210 - 50,316,480RGD
Cytogenetic Map17q21-q24UniSTS
HuRef1749,214,302 - 49,214,572UniSTS
TNG Radiation Hybrid Map1724813.0UniSTS
D1S3696  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map14q32.12UniSTS
Cytogenetic Map5q21.3UniSTS
Cytogenetic Map17q21-q24UniSTS
Cytogenetic Map5q21-q22UniSTS
Cytogenetic Map4q13.2UniSTS
Cytogenetic Map1q22UniSTS
Cytogenetic Map12q24.33UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 1659 558 954 479 1206 426 1648 662 732 260 981 1131 62 976 814 3
Low 779 2432 772 145 737 39 2708 1535 3002 159 476 466 112 1 228 1974 3 2
Below cutoff 1 4 2 3

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001102402 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001330377 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001330378 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_021213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017024913 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047436499 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047436500 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047436501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047436502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047436503 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047436504 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054316827 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054316828 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054316829 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001752576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001752577 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_008484868 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_008484869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_243677 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC009837 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC090618 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC091155 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF087857 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF114430 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF151638 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH008388 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK024667 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK058120 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK314509 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW298344 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW369326 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC005112 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC012084 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE245218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM153142 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM549250 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM907258 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX648199 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENST00000268896   ⟹   ENSP00000268896
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1755,751,051 - 55,777,374 (+)Ensembl
RefSeq Acc Id: ENST00000325214   ⟹   ENSP00000325181
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1755,751,400 - 55,777,374 (+)Ensembl
RefSeq Acc Id: ENST00000417982   ⟹   ENSP00000415185
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1755,751,105 - 55,777,373 (+)Ensembl
RefSeq Acc Id: ENST00000571489
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1755,768,847 - 55,777,387 (+)Ensembl
RefSeq Acc Id: ENST00000572536   ⟹   ENSP00000461676
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1755,773,736 - 55,823,090 (+)Ensembl
RefSeq Acc Id: ENST00000573500   ⟹   ENSP00000460437
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1755,751,094 - 55,823,090 (+)Ensembl
RefSeq Acc Id: ENST00000576183   ⟹   ENSP00000459793
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1755,751,061 - 55,777,368 (+)Ensembl
RefSeq Acc Id: ENST00000576221
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1755,771,177 - 55,842,830 (+)Ensembl
RefSeq Acc Id: NM_001102402   ⟹   NP_001095872
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381755,751,051 - 55,777,374 (+)NCBI
GRCh371753,828,340 - 53,920,522 (+)NCBI
Build 361751,183,355 - 51,209,747 (+)NCBI Archive
Celera1750,290,127 - 50,316,517 (+)RGD
HuRef1749,187,946 - 49,214,609 (+)ENTREZGENE
CHM1_11753,893,381 - 53,919,657 (+)NCBI
T2T-CHM13v2.01756,627,170 - 56,653,488 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001330377   ⟹   NP_001317306
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381755,751,051 - 55,777,374 (+)NCBI
T2T-CHM13v2.01756,627,170 - 56,653,488 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001330378   ⟹   NP_001317307
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381755,751,051 - 55,823,137 (+)NCBI
T2T-CHM13v2.01756,627,170 - 56,699,281 (+)NCBI
Sequence:
RefSeq Acc Id: NM_021213   ⟹   NP_067036
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381755,751,051 - 55,777,374 (+)NCBI
GRCh371753,828,340 - 53,920,522 (+)NCBI
Build 361751,183,355 - 51,209,747 (+)NCBI Archive
Celera1750,290,127 - 50,316,517 (+)RGD
HuRef1749,187,946 - 49,214,609 (+)ENTREZGENE
CHM1_11753,893,255 - 53,919,657 (+)NCBI
T2T-CHM13v2.01756,627,170 - 56,653,488 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017024913   ⟹   XP_016880402
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381755,751,051 - 55,777,374 (+)NCBI
Sequence:
RefSeq Acc Id: XM_047436499   ⟹   XP_047292455
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381755,751,051 - 55,843,507 (+)NCBI
RefSeq Acc Id: XM_047436500   ⟹   XP_047292456
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381755,751,051 - 55,852,715 (+)NCBI
RefSeq Acc Id: XM_047436501   ⟹   XP_047292457
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381755,751,051 - 55,843,507 (+)NCBI
RefSeq Acc Id: XM_047436502   ⟹   XP_047292458
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381755,751,051 - 55,843,507 (+)NCBI
RefSeq Acc Id: XM_047436503   ⟹   XP_047292459
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381755,751,384 - 55,843,507 (+)NCBI
RefSeq Acc Id: XM_047436504   ⟹   XP_047292460
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381755,751,051 - 55,773,743 (+)NCBI
RefSeq Acc Id: XM_054316827   ⟹   XP_054172802
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01756,627,170 - 56,699,281 (+)NCBI
RefSeq Acc Id: XM_054316828   ⟹   XP_054172803
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01756,627,170 - 56,649,857 (+)NCBI
RefSeq Acc Id: XM_054316829   ⟹   XP_054172804
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01756,627,170 - 56,653,488 (+)NCBI
RefSeq Acc Id: XR_008484868
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01756,627,170 - 56,721,145 (+)NCBI
RefSeq Acc Id: XR_008484869
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01756,627,170 - 56,719,937 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001095872 (Get FASTA)   NCBI Sequence Viewer  
  NP_001317306 (Get FASTA)   NCBI Sequence Viewer  
  NP_001317307 (Get FASTA)   NCBI Sequence Viewer  
  NP_067036 (Get FASTA)   NCBI Sequence Viewer  
  XP_016880402 (Get FASTA)   NCBI Sequence Viewer  
  XP_047292455 (Get FASTA)   NCBI Sequence Viewer  
  XP_047292456 (Get FASTA)   NCBI Sequence Viewer  
  XP_047292457 (Get FASTA)   NCBI Sequence Viewer  
  XP_047292458 (Get FASTA)   NCBI Sequence Viewer  
  XP_047292459 (Get FASTA)   NCBI Sequence Viewer  
  XP_047292460 (Get FASTA)   NCBI Sequence Viewer  
  XP_054172802 (Get FASTA)   NCBI Sequence Viewer  
  XP_054172803 (Get FASTA)   NCBI Sequence Viewer  
  XP_054172804 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAF02536 (Get FASTA)   NCBI Sequence Viewer  
  AAF08345 (Get FASTA)   NCBI Sequence Viewer  
  AAF08347 (Get FASTA)   NCBI Sequence Viewer  
  AAH05112 (Get FASTA)   NCBI Sequence Viewer  
  AAH12084 (Get FASTA)   NCBI Sequence Viewer  
  AAP97167 (Get FASTA)   NCBI Sequence Viewer  
  BAG37109 (Get FASTA)   NCBI Sequence Viewer  
  EAW94533 (Get FASTA)   NCBI Sequence Viewer  
  EAW94534 (Get FASTA)   NCBI Sequence Viewer  
  EAW94535 (Get FASTA)   NCBI Sequence Viewer  
  EAW94536 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000268896
  ENSP00000268896.4
  ENSP00000325181
  ENSP00000325181.5
  ENSP00000415185.2
  ENSP00000459793
  ENSP00000459793.1
  ENSP00000460437
  ENSP00000460437.1
  ENSP00000461676.1
GenBank Protein Q9UKL6 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_067036   ⟸   NM_021213
- Peptide Label: isoform 1
- UniProtKB: Q9UIT3 (UniProtKB/Swiss-Prot),   Q9BSC9 (UniProtKB/Swiss-Prot),   Q9UKW7 (UniProtKB/Swiss-Prot),   Q9UKL6 (UniProtKB/Swiss-Prot),   Q549N3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001095872   ⟸   NM_001102402
- Peptide Label: isoform 2
- UniProtKB: Q9UKL6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_016880402   ⟸   XM_017024913
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: NP_001317307   ⟸   NM_001330378
- Peptide Label: isoform 4
- UniProtKB: I3L3H0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001317306   ⟸   NM_001330377
- Peptide Label: isoform 3
- UniProtKB: I3L2M9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000268896   ⟸   ENST00000268896
RefSeq Acc Id: ENSP00000461676   ⟸   ENST00000572536
RefSeq Acc Id: ENSP00000460437   ⟸   ENST00000573500
RefSeq Acc Id: ENSP00000415185   ⟸   ENST00000417982
RefSeq Acc Id: ENSP00000325181   ⟸   ENST00000325214
RefSeq Acc Id: ENSP00000459793   ⟸   ENST00000576183
RefSeq Acc Id: XP_047292456   ⟸   XM_047436500
- Peptide Label: isoform X1
- UniProtKB: I3L3H0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_047292458   ⟸   XM_047436502
- Peptide Label: isoform X2
RefSeq Acc Id: XP_047292455   ⟸   XM_047436499
- Peptide Label: isoform X1
- UniProtKB: I3L3H0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_047292457   ⟸   XM_047436501
- Peptide Label: isoform X1
- UniProtKB: I3L3H0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_047292460   ⟸   XM_047436504
- Peptide Label: isoform X3
RefSeq Acc Id: XP_047292459   ⟸   XM_047436503
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054172802   ⟸   XM_054316827
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054172804   ⟸   XM_054316829
- Peptide Label: isoform X4
RefSeq Acc Id: XP_054172803   ⟸   XM_054316828
- Peptide Label: isoform X3
Protein Domains
START

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9UKL6-F1-model_v2 AlphaFold Q9UKL6 1-214 view protein structure

Promoters
RGD ID:6794425
Promoter ID:HG_KWN:26639
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   HeLa_S3,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_001102402,   NM_021213,   UC010DCG.1,   UC010DCH.1
Position:
Human AssemblyChrPosition (strand)Source
Build 361751,183,281 - 51,183,781 (+)MPROMDB
RGD ID:7235737
Promoter ID:EPDNEW_H23614
Type:initiation region
Name:PCTP_1
Description:phosphatidylcholine transfer protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H23611  EPDNEW_H23613  EPDNEW_H23610  EPDNEW_H23615  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381755,751,053 - 55,751,113EPDNEW
RGD ID:7235743
Promoter ID:EPDNEW_H23615
Type:initiation region
Name:PCTP_2
Description:phosphatidylcholine transfer protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H23611  EPDNEW_H23613  EPDNEW_H23610  EPDNEW_H23614  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381755,751,386 - 55,751,446EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:8752 AgrOrtholog
COSMIC PCTP COSMIC
Ensembl Genes ENSG00000141179 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000268896 ENTREZGENE
  ENST00000268896.10 UniProtKB/Swiss-Prot
  ENST00000325214 ENTREZGENE
  ENST00000325214.10 UniProtKB/Swiss-Prot
  ENST00000417982.6 UniProtKB/TrEMBL
  ENST00000572536.1 UniProtKB/TrEMBL
  ENST00000573500 ENTREZGENE
  ENST00000573500.5 UniProtKB/TrEMBL
  ENST00000576183 ENTREZGENE
  ENST00000576183.5 UniProtKB/TrEMBL
Gene3D-CATH 3.30.530.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000141179 GTEx
HGNC ID HGNC:8752 ENTREZGENE
Human Proteome Map PCTP Human Proteome Map
InterPro STARD2_START UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  START-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  START_lipid-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:58488 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 58488 ENTREZGENE
OMIM 606055 OMIM
PANTHER PHOSPHATIDYLCHOLINE TRANSFER PROTEIN UniProtKB/Swiss-Prot
  PHOSPHATIDYLCHOLINE TRANSFER PROTEIN UniProtKB/Swiss-Prot
  PHOSPHATIDYLCHOLINE TRANSFER PROTEIN UniProtKB/TrEMBL
  PHOSPHATIDYLCHOLINE TRANSFER PROTEIN UniProtKB/TrEMBL
Pfam START UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA33098 PharmGKB
PRINTS F138DOMAIN UniProtKB/TrEMBL
PROSITE START UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART START UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Bet v1-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt I3L2M9 ENTREZGENE, UniProtKB/TrEMBL
  I3L3H0 ENTREZGENE, UniProtKB/TrEMBL
  I3L4Z8_HUMAN UniProtKB/TrEMBL
  J3QT99_HUMAN UniProtKB/TrEMBL
  L8EA98_HUMAN UniProtKB/TrEMBL
  PPCT_HUMAN UniProtKB/Swiss-Prot
  Q549N3 ENTREZGENE, UniProtKB/TrEMBL
  Q9BSC9 ENTREZGENE
  Q9UIT3 ENTREZGENE
  Q9UKL6 ENTREZGENE
  Q9UKW7 ENTREZGENE
UniProt Secondary Q9BSC9 UniProtKB/Swiss-Prot
  Q9UIT3 UniProtKB/Swiss-Prot
  Q9UKW7 UniProtKB/Swiss-Prot