ATG5 (autophagy related 5) - Rat Genome Database

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Gene: ATG5 (autophagy related 5) Homo sapiens
Analyze
Symbol: ATG5
Name: autophagy related 5
RGD ID: 1353398
HGNC Page HGNC:589
Description: Enables Atg8-family ligase activity. Involved in several processes, including macroautophagy; negative regulation of defense response to virus; and positive regulation of viral translation. Acts upstream of or within negative regulation of autophagic cell death. Located in autophagosome and membrane. Part of Atg12-Atg5-Atg16 complex. Implicated in autosomal recessive spinocerebellar ataxia 25.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: APG5; APG5 (autophagy 5, S. cerevisiae)-like; APG5 autophagy 5-like; apg5 autophagy 5-like (s. cerevisiae); APG5-LIKE; APG5L; apoptosis specific protein; apoptosis-specific protein; ASP; ATG5 autophagy related 5 homolog; ATG5 autophagy related 5-like; autophagy protein 5; hAPG5; SCAR25
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386106,184,476 - 106,325,760 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6106,045,423 - 106,325,791 (-)EnsemblGRCh38hg38GRCh38
GRCh376106,632,351 - 106,773,635 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366106,739,045 - 106,880,388 (-)NCBINCBI36Build 36hg18NCBI36
Build 346106,739,044 - 106,880,359NCBI
Celera6107,253,905 - 107,395,251 (-)NCBICelera
Cytogenetic Map6q21NCBI
HuRef6104,079,375 - 104,220,613 (-)NCBIHuRef
CHM1_16106,894,763 - 107,036,172 (-)NCBICHM1_1
T2T-CHM13v2.06107,360,315 - 107,501,922 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-Tetrandrine  (EXP)
(-)-citrinin  (ISO)
(-)-epigallocatechin 3-gallate  (EXP)
1,2-dimethylhydrazine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one  (EXP)
2-hydroxyethyl methacrylate  (EXP)
2-hydroxypropanoic acid  (EXP)
3,3',5-triiodo-L-thyronine  (ISO)
3-chloropropane-1,2-diol  (ISO)
3-hydroxybutyric acid  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (EXP)
3-methyladenine  (EXP,ISO)
4'-epidoxorubicin  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxynon-2-enal  (EXP)
4-nonylphenol  (ISO)
4-phenylbutyric acid  (ISO)
5-aza-2'-deoxycytidine  (ISO)
acrolein  (EXP)
acrylamide  (EXP,ISO)
Aescin  (EXP,ISO)
aflatoxin B1  (EXP)
AICA ribonucleotide  (EXP)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (EXP)
alpha,alpha-trehalose  (ISO)
alpha-amanitin  (EXP,ISO)
alpha-D-galactose  (ISO)
alpha-pinene  (EXP)
Alpinetin  (EXP,ISO)
amiodarone  (EXP)
antirheumatic drug  (EXP)
aristolochic acid A  (EXP,ISO)
arsenite(3-)  (EXP)
arsenous acid  (EXP,ISO)
artesunate  (EXP)
atorvastatin calcium  (ISO)
atrazine  (ISO)
bafilomycin A1  (EXP,ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bortezomib  (ISO)
buprofezin  (EXP)
butachlor  (ISO)
butyric acid  (EXP)
cadmium acetate  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (EXP)
camptothecin  (EXP)
candesartan  (ISO)
capsaicin  (EXP)
carbamazepine  (ISO)
carbon disulfide  (ISO)
carbon nanotube  (EXP,ISO)
carglumic acid  (ISO)
CGP 52608  (EXP)
chloroquine  (EXP,ISO)
chromium(6+)  (ISO)
cisplatin  (EXP,ISO)
colistin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
cordycepin  (EXP)
crocin-1  (ISO)
curcumin  (EXP,ISO)
Curcumol  (ISO)
cyclophosphamide  (ISO)
cyclosporin A  (EXP)
cypermethrin  (EXP)
D-glucose  (ISO)
dapagliflozin  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (EXP)
dextran sulfate  (ISO)
diarsenic trioxide  (EXP,ISO)
dibutyl phthalate  (ISO)
dicrotophos  (EXP)
dieldrin  (ISO)
diisononyl phthalate  (EXP)
dioxygen  (ISO)
diphenhydramine  (ISO)
diquat  (EXP)
disodium selenite  (EXP)
Doramectin  (EXP,ISO)
doxorubicin  (EXP,ISO)
ellagic acid  (EXP)
embelin  (EXP)
erastin  (ISO)
erlotinib hydrochloride  (EXP)
ethanol  (EXP,ISO)
ferric oxide  (ISO)
ferrostatin-1  (ISO)
fingolimod hydrochloride  (EXP)
flavokawain B  (EXP)
flutamide  (ISO)
folic acid  (ISO)
Fusaric acid  (EXP)
galactose  (ISO)
gefitinib  (EXP)
genistein  (EXP)
geraniol  (EXP)
glucose  (ISO)
glutathione  (ISO)
glycochenodeoxycholic acid  (EXP)
glyphosate  (EXP)
gossypetin  (EXP)
hesperetin  (ISO)
hexadecanoic acid  (EXP,ISO)
HU-308  (ISO)
hyaluronic acid  (ISO)
hydroquinone  (EXP)
indometacin  (EXP)
ivermectin  (EXP)
JTE-013  (ISO)
kainic acid  (ISO)
L-leucine  (ISO)
lead diacetate  (ISO)
lead(0)  (ISO)
levamisole  (ISO)
lipopolysaccharide  (ISO)
luteolin  (EXP,ISO)
LY294002  (ISO)
lycopene  (ISO)
melatonin  (ISO)
menadione  (ISO)
metformin  (ISO)
methamphetamine  (ISO)
methoxychlor  (ISO)
methylisothiazolinone  (EXP)
methylmercury chloride  (EXP,ISO)
methylphenidate  (ISO)
microcystin-LR  (ISO)
mitoxantrone  (EXP)
MJN110  (ISO)
N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide  (ISO)
N-acetyl-L-cysteine  (EXP,ISO)
N-methyl-4-phenylpyridinium  (EXP)
NADP zwitterion  (ISO)
NADP(+)  (ISO)
nickel atom  (EXP,ISO)
nickel dichloride  (ISO)
Nonidet P-40  (EXP)
obeticholic acid  (ISO)
oleanolic acid  (EXP,ISO)
oleic acid  (EXP)
oligopeptide  (EXP)
ozone  (EXP)
p-menthan-3-ol  (EXP)
Paeonol  (ISO)
paracetamol  (ISO)
paraquat  (EXP,ISO)
patulin  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
potassium chromate  (EXP)
potassium dichromate  (ISO)
promethazine  (EXP)
propiconazole  (ISO)
psoralen  (ISO)
pterostilbene  (EXP,ISO)
pyrroloquinoline quinone  (EXP)
quercetin  (EXP,ISO)
rac-lactic acid  (EXP)
raloxifene  (EXP)
reactive oxygen species  (EXP)
resveratrol  (EXP,ISO)
rotenone  (EXP,ISO)
roxadustat  (ISO)
ruthenium red  (ISO)
Sanggenon C  (ISO)
SB 203580  (EXP)
sevoflurane  (EXP)
silicon dioxide  (ISO)
sirolimus  (EXP,ISO)
sodium arsenite  (EXP,ISO)
sodium fluoride  (ISO)
Soman  (ISO)
sorafenib  (EXP)
sphingosine 1-phosphate  (ISO)
stilbenoid  (EXP)
streptozocin  (ISO)
swainsonine  (ISO)
T-2 toxin  (ISO)
temozolomide  (EXP)
tert-butyl hydroperoxide  (EXP)
tetrachloromethane  (ISO)
thiacloprid  (ISO)
thymoquinone  (EXP)
titanium dioxide  (ISO)
trans-piceid  (EXP)
trifluoperazine  (EXP)
Triptolide  (ISO)
trovafloxacin  (EXP)
tunicamycin  (EXP,ISO)
tyloxapol  (ISO)
valproic acid  (EXP)
vitamin E  (ISO)
vorinostat  (EXP)
zearalenone  (ISO)
zinc atom  (EXP)
zinc oxide  (ISO)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
aggrephagy  (IBA,IEA,IMP)
antigen processing and presentation of endogenous antigen  (IEA)
apoptotic process  (IEA)
autophagosome assembly  (IBA,IDA,IEA,ISO,ISS)
autophagy  (IEA,IGI,IMP,ISO,ISS)
axonal transport  (IEA)
blood vessel remodeling  (IEA)
cardiac muscle cell apoptotic process  (IEA)
cellular response to nitrogen starvation  (IBA)
cellular response to nitrosative stress  (IEA)
cellular response to starvation  (IEA)
chaperone-mediated autophagy  (IEA)
chromatin organization  (IEA)
defense response to virus  (IEA)
establishment of localization in cell  (IEA)
heart contraction  (IEA)
immune system process  (IEA)
innate immune response  (IEA)
macroautophagy  (IEA,IMP,ISO)
mitophagy  (IBA)
mucus secretion  (IEA)
negative regulation of apoptotic process  (IEA,ISO)
negative regulation of autophagic cell death  (IMP)
negative regulation of cardiac muscle cell apoptotic process  (IEA)
negative regulation of defense response to virus  (IDA,IEA)
negative regulation of innate immune response  (IEA,ISO)
negative regulation of phagocytosis  (IEA)
negative regulation of protein ubiquitination  (IEA)
negative regulation of type I interferon production  (IEA,ISO)
negative stranded viral RNA replication  (IEA)
negative thymic T cell selection  (IEA)
otolith development  (IEA)
piecemeal microautophagy of the nucleus  (IBA)
positive regulation of autophagy  (IEA,ISO)
positive regulation of mucus secretion  (IEA)
positive regulation of stress granule assembly  (IEA,ISO)
positive regulation of viral translation  (IDA)
post-translational protein modification  (IEA,ISS)
postsynaptic modulation of chemical synaptic transmission  (IEA)
protein lipidation involved in autophagosome assembly  (ISO)
protein ubiquitination  (IEA)
regulation of autophagosome maturation  (IMP)
regulation of cilium assembly  (IEA,ISS)
regulation of cytokine production involved in immune response  (IEA)
regulation of postsynaptic membrane neurotransmitter receptor levels  (IEA)
regulation of reactive oxygen species metabolic process  (IEA)
regulation of release of sequestered calcium ion into cytosol  (IEA)
response to fluoride  (IEA,ISO)
response to fungus  (IEA)
response to iron(II) ion  (IEA,ISO)
response to xenobiotic stimulus  (IEA)
vasodilation  (IEA)
ventricular cardiac muscle cell development  (IEA)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. Trehalose delays the progression of amyotrophic lateral sclerosis by enhancing autophagy in motoneurons. Castillo K, etal., Autophagy. 2013 Sep;9(9):1308-20. doi: 10.4161/auto.25188. Epub 2013 Jun 6.
2. Cold ischemia-induced autophagy in rat lung tissue. Chen X, etal., Mol Med Rep. 2015 Apr;11(4):2513-9. doi: 10.3892/mmr.2014.2999. Epub 2014 Nov 26.
3. Upregulation of miR-96-5p by bone marrow mesenchymal stem cells and their exosomes alleviate non-alcoholic steatohepatitis: Emphasis on caspase-2 signaling inhibition. El-Derany MO and AbdelHamid SG, Biochem Pharmacol. 2021 Aug;190:114624. doi: 10.1016/j.bcp.2021.114624. Epub 2021 May 27.
4. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
5. Changes in autophagy after traumatic brain injury. Liu CL, etal., J Cereb Blood Flow Metab. 2008 Apr;28(4):674-83. Epub 2007 Dec 5.
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Early and sustained activation of autophagy in degenerating axons after spinal cord injury. Ribas VT, etal., Brain Pathol. 2015 Mar;25(2):157-70. doi: 10.1111/bpa.12170. Epub 2014 Sep 12.
10. Aliskiren ameliorates pressure overload-induced heart hypertrophy and fibrosis in mice. Weng LQ, etal., Acta Pharmacol Sin. 2014 Aug;35(8):1005-14. doi: 10.1038/aps.2014.45. Epub 2014 Jul 7.
11. Mammalian autophagy: core molecular machinery and signaling regulation. Yang Z and Klionsky DJ, Curr Opin Cell Biol. 2010 Apr;22(2):124-31. Epub 2009 Dec 23.
Additional References at PubMed
PMID:7796880   PMID:9563500   PMID:9852036   PMID:10702672   PMID:11096062   PMID:11266458   PMID:11349150   PMID:11725643   PMID:11825910   PMID:12207896   PMID:12417306   PMID:12477932  
PMID:12482611   PMID:12665549   PMID:12703993   PMID:14574404   PMID:14702039   PMID:15292400   PMID:15342556   PMID:15489334   PMID:15778222   PMID:16341674   PMID:16998475   PMID:17207965  
PMID:17353931   PMID:17709747   PMID:18296641   PMID:18353420   PMID:18448665   PMID:18787411   PMID:19066443   PMID:19124466   PMID:19148225   PMID:19194464   PMID:19197948   PMID:19273585  
PMID:19322201   PMID:19375507   PMID:19483105   PMID:19666601   PMID:19783847   PMID:19838193   PMID:19881538   PMID:19901552   PMID:20038797   PMID:20190558   PMID:20379614   PMID:20417604  
PMID:20529838   PMID:20562859   PMID:20580051   PMID:20639872   PMID:20697744   PMID:20962850   PMID:21068098   PMID:21241894   PMID:21575909   PMID:21622776   PMID:21655094   PMID:21664058  
PMID:21722286   PMID:21795849   PMID:21873635   PMID:21976705   PMID:21995634   PMID:22040493   PMID:22052905   PMID:22082872   PMID:22170153   PMID:22174682   PMID:22342342   PMID:22536318  
PMID:22658522   PMID:22740627   PMID:22749352   PMID:22847423   PMID:22863883   PMID:22982048   PMID:22993366   PMID:23075929   PMID:23093945   PMID:23202584   PMID:23235332   PMID:23242420  
PMID:23262492   PMID:23273568   PMID:23317196   PMID:23322078   PMID:23384565   PMID:23392225   PMID:23429496   PMID:23486359   PMID:23740937   PMID:23744296   PMID:23831471   PMID:23945651  
PMID:23997112   PMID:24027027   PMID:24186333   PMID:24191030   PMID:24205307   PMID:24269628   PMID:24300435   PMID:24324106   PMID:24390342   PMID:24582693   PMID:24705551   PMID:24727585  
PMID:24739953   PMID:24953774   PMID:24954904   PMID:25032862   PMID:25329677   PMID:25416956   PMID:25439980   PMID:25481044   PMID:25482163   PMID:25484072   PMID:25787994   PMID:25905985  
PMID:26039132   PMID:26083323   PMID:26186194   PMID:26240015   PMID:26282792   PMID:26344197   PMID:26420661   PMID:26491898   PMID:26509176   PMID:26673895   PMID:26701229   PMID:26747760  
PMID:26812546   PMID:26930546   PMID:26975471   PMID:27096233   PMID:27245739   PMID:27304991   PMID:27325703   PMID:27464255   PMID:27514536   PMID:27715410   PMID:27729742   PMID:27879200  
PMID:27960588   PMID:28067309   PMID:28102839   PMID:28231469   PMID:28253979   PMID:28274318   PMID:28294157   PMID:28389568   PMID:28514442   PMID:28594407   PMID:28651493   PMID:28684853  
PMID:28703297   PMID:28839236   PMID:28844669   PMID:28866627   PMID:28887323   PMID:28928221   PMID:28930552   PMID:28978663   PMID:28982601   PMID:28994404   PMID:29037992   PMID:29133525  
PMID:29229996   PMID:29360461   PMID:29367244   PMID:29368980   PMID:29455545   PMID:29467282   PMID:29472524   PMID:29634390   PMID:29759048   PMID:30196744   PMID:30286180   PMID:30303264  
PMID:30340022   PMID:30365113   PMID:30383396   PMID:30704939   PMID:30710750   PMID:30716314   PMID:30894637   PMID:30907204   PMID:30964170   PMID:31006538   PMID:31383875   PMID:31502570  
PMID:31515488   PMID:31558875   PMID:31570703   PMID:31585730   PMID:31612776   PMID:31636955   PMID:31672943   PMID:31729038   PMID:31748850   PMID:31894301   PMID:32098672   PMID:32129924  
PMID:32186433   PMID:32296183   PMID:32376155   PMID:32453962   PMID:32557806   PMID:32686156   PMID:32707918   PMID:32814053   PMID:32853020   PMID:32876514   PMID:32890892   PMID:32994395  
PMID:33024031   PMID:33172148   PMID:33277367   PMID:33487631   PMID:33598715   PMID:33645631   PMID:33752242   PMID:33812933   PMID:33831322   PMID:33921398   PMID:33961781   PMID:34226595  
PMID:34453672   PMID:34499929   PMID:34560101   PMID:34661876   PMID:34755101   PMID:34903064   PMID:35271311   PMID:35377342   PMID:35518570   PMID:35551488   PMID:35831314   PMID:35836404  
PMID:35914814   PMID:36197771   PMID:36223738   PMID:36342387   PMID:36357363   PMID:36473201   PMID:36528756   PMID:36576150   PMID:36629882   PMID:36805797   PMID:36912305   PMID:37054706  
PMID:37083684   PMID:37151889   PMID:37155854   PMID:37460898   PMID:37487784   PMID:37596850   PMID:37858134   PMID:37991129   PMID:38009708   PMID:38037161   PMID:38136993   PMID:38279424  
PMID:38305285   PMID:38477302   PMID:38511768   PMID:38530706   PMID:38747016  


Genomics

Comparative Map Data
ATG5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386106,184,476 - 106,325,760 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6106,045,423 - 106,325,791 (-)EnsemblGRCh38hg38GRCh38
GRCh376106,632,351 - 106,773,635 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366106,739,045 - 106,880,388 (-)NCBINCBI36Build 36hg18NCBI36
Build 346106,739,044 - 106,880,359NCBI
Celera6107,253,905 - 107,395,251 (-)NCBICelera
Cytogenetic Map6q21NCBI
HuRef6104,079,375 - 104,220,613 (-)NCBIHuRef
CHM1_16106,894,763 - 107,036,172 (-)NCBICHM1_1
T2T-CHM13v2.06107,360,315 - 107,501,922 (-)NCBIT2T-CHM13v2.0
Atg5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391044,144,325 - 44,240,295 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1044,144,354 - 44,240,287 (+)EnsemblGRCm39 Ensembl
GRCm381044,268,322 - 44,364,299 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1044,268,358 - 44,364,291 (+)EnsemblGRCm38mm10GRCm38
MGSCv371043,988,164 - 44,084,097 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361043,956,773 - 44,052,706 (+)NCBIMGSCv36mm8
Celera1045,141,131 - 45,237,099 (+)NCBICelera
Cytogenetic Map10B2NCBI
cM Map1023.24NCBI
Atg5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82049,380,835 - 49,471,826 (+)NCBIGRCr8
mRatBN7.22047,798,217 - 47,889,216 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2047,798,290 - 47,889,209 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2049,539,098 - 49,629,485 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02049,188,983 - 49,279,371 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02049,872,609 - 49,962,985 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02049,301,783 - 49,393,147 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2049,318,308 - 49,393,140 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02050,934,688 - 51,026,125 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42048,273,977 - 48,366,743 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12048,302,673 - 48,395,435 (+)NCBI
Celera2052,117,260 - 52,207,732 (-)NCBICelera
Cytogenetic Map20q13NCBI
Atg5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541131,522,420 - 31,646,827 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541131,501,191 - 31,646,407 (-)NCBIChiLan1.0ChiLan1.0
ATG5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25126,183,703 - 126,346,578 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16124,071,501 - 124,233,849 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06103,997,824 - 104,140,931 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16107,871,201 - 108,027,064 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6107,871,208 - 108,013,807 (-)Ensemblpanpan1.1panPan2
ATG5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11263,565,859 - 63,692,383 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1263,567,568 - 63,683,485 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1263,353,188 - 63,480,151 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01264,411,072 - 64,538,081 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1264,410,753 - 64,538,102 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11263,770,621 - 63,897,766 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01263,612,694 - 63,739,640 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01263,886,649 - 64,013,653 (-)NCBIUU_Cfam_GSD_1.0
Atg5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494698,484,245 - 98,610,566 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365642,758,598 - 2,885,420 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365642,759,085 - 2,885,394 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ATG5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl172,270,799 - 72,520,396 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1172,343,950 - 72,520,402 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ATG5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11367,482,538 - 67,619,201 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1367,482,595 - 67,617,902 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604039,817,584 - 39,954,576 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Atg5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478015,987,397 - 16,124,151 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478015,987,483 - 16,124,158 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ATG5
23 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 6q21(chr6:106143607-106716817)x3 copy number gain See cases [RCV000053366] Chr6:106143607..106716817 [GRCh38]
Chr6:106591482..107143252 [GRCh37]
Chr6:106698175..107271385 [NCBI36]
Chr6:6q21
uncertain significance
NM_004849.3(ATG5):c.610C>T (p.Arg204Cys) single nucleotide variant Malignant melanoma [RCV000067058] Chr6:106202053 [GRCh38]
Chr6:106649928 [GRCh37]
Chr6:106756621 [NCBI36]
Chr6:6q21
not provided
GRCh38/hg38 6q16.3-21(chr6:102356502-111049879)x1 copy number loss See cases [RCV000134806] Chr6:102356502..111049879 [GRCh38]
Chr6:102804377..111371082 [GRCh37]
Chr6:102911070..111477775 [NCBI36]
Chr6:6q16.3-21
pathogenic
GRCh38/hg38 6q13-24.1(chr6:74382807-142040500)x3 copy number gain See cases [RCV000139729] Chr6:74382807..142040500 [GRCh38]
Chr6:75092523..142361637 [GRCh37]
Chr6:75149243..142403330 [NCBI36]
Chr6:6q13-24.1
pathogenic
GRCh38/hg38 6q16.1-22.31(chr6:96609994-122161548)x1 copy number loss See cases [RCV000139465] Chr6:96609994..122161548 [GRCh38]
Chr6:97057870..122482694 [GRCh37]
Chr6:97164591..122524393 [NCBI36]
Chr6:6q16.1-22.31
pathogenic
GRCh38/hg38 6q16.3-21(chr6:103279465-113934239)x1 copy number loss See cases [RCV000142287] Chr6:103279465..113934239 [GRCh38]
Chr6:103727340..114255403 [GRCh37]
Chr6:103834033..114362096 [NCBI36]
Chr6:6q16.3-21
pathogenic
GRCh38/hg38 6q21(chr6:105922825-106683920)x3 copy number gain See cases [RCV000143107] Chr6:105922825..106683920 [GRCh38]
Chr6:106370700..107131795 [GRCh37]
Chr6:106477393..107238488 [NCBI36]
Chr6:6q21
uncertain significance
GRCh38/hg38 6q16.3-22.31(chr6:100054889-120488154)x1 copy number loss See cases [RCV000143227] Chr6:100054889..120488154 [GRCh38]
Chr6:100502765..120809300 [GRCh37]
Chr6:100609486..120850999 [NCBI36]
Chr6:6q16.3-22.31
pathogenic
GRCh38/hg38 6q21(chr6:105833853-106582592)x3 copy number gain See cases [RCV000143257] Chr6:105833853..106582592 [GRCh38]
Chr6:106281728..107030467 [GRCh37]
Chr6:106388421..107137160 [NCBI36]
Chr6:6q21
uncertain significance
GRCh37/hg19 6q21(chr6:106281728-107019722)x3 copy number gain See cases [RCV000240329] Chr6:106281728..107019722 [GRCh37]
Chr6:6q21
uncertain significance
NM_004849.4(ATG5):c.679A>G (p.Ile227Val) single nucleotide variant not specified [RCV004320386] Chr6:106201984 [GRCh38]
Chr6:106649859 [GRCh37]
Chr6:6q21
likely benign
GRCh37/hg19 6q21(chr6:105930050-107970442)x1 copy number loss See cases [RCV000446119] Chr6:105930050..107970442 [GRCh37]
Chr6:6q21
uncertain significance
GRCh37/hg19 6q14.3-22.31(chr6:85988428-120548687)x1 copy number loss See cases [RCV000445666] Chr6:85988428..120548687 [GRCh37]
Chr6:6q14.3-22.31
pathogenic
GRCh37/hg19 6q21(chr6:106394584-107635657)x1 copy number loss See cases [RCV000445829] Chr6:106394584..107635657 [GRCh37]
Chr6:6q21
uncertain significance
GRCh37/hg19 6q21(chr6:105550491-107378236)x1 copy number loss See cases [RCV000448307] Chr6:105550491..107378236 [GRCh37]
Chr6:6q21
uncertain significance
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482)x3 copy number gain See cases [RCV000512067] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482) copy number gain See cases [RCV000510595] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6q16.1-21(chr6:97384446-110247755)x1 copy number loss See cases [RCV000510703] Chr6:97384446..110247755 [GRCh37]
Chr6:6q16.1-21
pathogenic
NM_004849.4(ATG5):c.366A>T (p.Glu122Asp) single nucleotide variant Spinocerebellar ataxia, autosomal recessive 25 [RCV000496077] Chr6:106279773 [GRCh38]
Chr6:106727648 [GRCh37]
Chr6:6q21
pathogenic
GRCh37/hg19 6q16.1-21(chr6:94202605-109878834)x1 copy number loss See cases [RCV000512470] Chr6:94202605..109878834 [GRCh37]
Chr6:6q16.1-21
pathogenic
GRCh37/hg19 6q16.1-22.1(chr6:95549951-116684929)x1 copy number loss not provided [RCV000682693] Chr6:95549951..116684929 [GRCh37]
Chr6:6q16.1-22.1
pathogenic
NM_004849.4(ATG5):c.62C>G (p.Thr21Arg) single nucleotide variant not provided [RCV000677279] Chr6:106316147 [GRCh38]
Chr6:106764022 [GRCh37]
Chr6:6q21
uncertain significance
GRCh37/hg19 6p25.3-q27(chr6:108666-170980171)x3 copy number gain not provided [RCV000745403] Chr6:108666..170980171 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:60107-171054786)x3 copy number gain not provided [RCV000745400] Chr6:60107..171054786 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:165632-170919470)x3 copy number gain not provided [RCV000745404] Chr6:165632..170919470 [GRCh37]
Chr6:6p25.3-q27
pathogenic
NM_004849.4(ATG5):c.66A>G (p.Leu22=) single nucleotide variant not provided [RCV000970840] Chr6:106316143 [GRCh38]
Chr6:106764018 [GRCh37]
Chr6:6q21
benign
NM_004849.4(ATG5):c.237-8A>G single nucleotide variant not provided [RCV000971889] Chr6:106293114 [GRCh38]
Chr6:106740989 [GRCh37]
Chr6:6q21
benign
NM_004849.4(ATG5):c.385A>G (p.Met129Val) single nucleotide variant ATG5-related disorder [RCV003923068]|not provided [RCV000905765] Chr6:106279754 [GRCh38]
Chr6:106727629 [GRCh37]
Chr6:6q21
benign
NM_004849.4(ATG5):c.193A>G (p.Ile65Val) single nucleotide variant not provided [RCV000949303] Chr6:106308407 [GRCh38]
Chr6:106756282 [GRCh37]
Chr6:6q21
benign
GRCh37/hg19 6q21(chr6:106427169-106641115)x3 copy number gain not provided [RCV001007554] Chr6:106427169..106641115 [GRCh37]
Chr6:6q21
uncertain significance
GRCh37/hg19 6q21(chr6:106638006-107421916)x3 copy number gain not provided [RCV001007555] Chr6:106638006..107421916 [GRCh37]
Chr6:6q21
uncertain significance
GRCh37/hg19 6q16.3-22.1(chr6:101296547-117004249)x3 copy number gain Microcephaly [RCV001251053] Chr6:101296547..117004249 [GRCh37]
Chr6:6q16.3-22.1
pathogenic
GRCh37/hg19 6q21(chr6:106330947-106730123)x3 copy number gain not provided [RCV001259395] Chr6:106330947..106730123 [GRCh37]
Chr6:6q21
uncertain significance
GRCh37/hg19 6q16.1-21(chr6:98949950-114533905)x1 copy number loss Deletion 6q16 q21 [RCV001263224] Chr6:98949950..114533905 [GRCh37]
Chr6:6q16.1-21
pathogenic
NC_000006.11:g.(?_106756239)_(107365536_?)dup duplication not provided [RCV001301318] Chr6:106756239..107365536 [GRCh37]
Chr6:6q21
uncertain significance
GRCh37/hg19 6q21(chr6:105930050-107970442) copy number loss not specified [RCV002053605] Chr6:105930050..107970442 [GRCh37]
Chr6:6q21
uncertain significance
GRCh37/hg19 6q15-22.2(chr6:92054891-118329651) copy number loss not specified [RCV002053598] Chr6:92054891..118329651 [GRCh37]
Chr6:6q15-22.2
pathogenic
GRCh37/hg19 6q21(chr6:106602280-106903888) copy number gain not specified [RCV002053606] Chr6:106602280..106903888 [GRCh37]
Chr6:6q21
uncertain significance
GRCh37/hg19 6q14.3-22.31(chr6:85988428-120548687) copy number loss not specified [RCV002053595] Chr6:85988428..120548687 [GRCh37]
Chr6:6q14.3-22.31
pathogenic
GRCh37/hg19 6q21(chr6:105550491-107378236) copy number loss not specified [RCV002053604] Chr6:105550491..107378236 [GRCh37]
Chr6:6q21
uncertain significance
NM_004849.4(ATG5):c.559T>A (p.Phe187Ile) single nucleotide variant not specified [RCV004156438] Chr6:106248164 [GRCh38]
Chr6:106696039 [GRCh37]
Chr6:6q21
uncertain significance
NM_004849.4(ATG5):c.361A>G (p.Ile121Val) single nucleotide variant not specified [RCV004261022] Chr6:106279778 [GRCh38]
Chr6:106727653 [GRCh37]
Chr6:6q21
uncertain significance
GRCh37/hg19 6q15-21(chr6:92468126-109410569)x1 copy number loss not provided [RCV003482928] Chr6:92468126..109410569 [GRCh37]
Chr6:6q15-21
pathogenic
NM_004849.4(ATG5):c.107A>G (p.Tyr36Cys) single nucleotide variant not specified [RCV004425396] Chr6:106316102 [GRCh38]
Chr6:106763977 [GRCh37]
Chr6:6q21
uncertain significance
NM_004849.4(ATG5):c.444A>G (p.Lys148=) single nucleotide variant ATG5-related disorder [RCV003976475] Chr6:106279695 [GRCh38]
Chr6:106727570 [GRCh37]
Chr6:6q21
benign
NM_004849.4(ATG5):c.326A>G (p.Glu109Gly) single nucleotide variant not specified [RCV004670466] Chr6:106279813 [GRCh38]
Chr6:106727688 [GRCh37]
Chr6:6q21
uncertain significance
NM_004849.4(ATG5):c.420A>C (p.Gln140His) single nucleotide variant not specified [RCV004870254] Chr6:106279719 [GRCh38]
Chr6:106727594 [GRCh37]
Chr6:6q21
uncertain significance
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:2818
Count of miRNA genes:574
Interacting mature miRNAs:639
Transcripts:ENST00000343245, ENST00000360666, ENST00000369070, ENST00000369076, ENST00000475645, ENST00000476518
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
597019924GWAS1115998_Hlimited scleroderma QTL GWAS1115998 (human)0.0000008limited scleroderma6106207742106207743Human
597229595GWAS1325669_Hasthma QTL GWAS1325669 (human)0.000001asthma6106219660106219661Human
597216602GWAS1312676_Hchildhood onset asthma QTL GWAS1312676 (human)9e-21childhood onset asthma6106219660106219661Human
597046034GWAS1142108_Hatopic asthma QTL GWAS1142108 (human)4e-11atopic asthma6106214866106214867Human
597144786GWAS1240860_Hage of onset of childhood onset asthma QTL GWAS1240860 (human)3e-10age of onset of childhood onset asthma6106198777106198778Human
597057107GWAS1153181_Heosinophil count QTL GWAS1153181 (human)1e-17eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)6106219660106219661Human
597257118GWAS1353192_Hmultiple myeloma QTL GWAS1353192 (human)2e-16multiple myeloma6106189027106189028Human
407249601GWAS898577_Hasthma QTL GWAS898577 (human)7e-10asthma6106219660106219661Human
597281054GWAS1377128_Hrheumatoid arthritis QTL GWAS1377128 (human)2e-08rheumatoid arthritis6106279340106279341Human
597184991GWAS1281065_Hsystemic scleroderma QTL GWAS1281065 (human)2e-08systemic scleroderma6106286165106286166Human
406965513GWAS614489_Hrheumatoid arthritis QTL GWAS614489 (human)4e-08rheumatoid arthritis6106219660106219661Human
406965512GWAS614488_Hrheumatoid arthritis QTL GWAS614488 (human)8e-10rheumatoid arthritis6106219660106219661Human
597594964GWAS1651824_Heosinophil count QTL GWAS1651824 (human)1e-15eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)6106307720106307721Human
597276818GWAS1372892_Hrheumatoid arthritis, anti-citrullinated protein antibody seropositivity, rheumatoid factor seropositivity measurement QTL GWAS1372892 (human)7e-15rheumatoid arthritis, anti-citrullinated protein antibody seropositivity, rheumatoid factor seropositivity measurement6106279340106279341Human
597275282GWAS1371356_Hrheumatoid arthritis, anti-citrullinated protein antibody seropositivity, rheumatoid factor seropositivity measurement QTL GWAS1371356 (human)0.0000008rheumatoid arthritis, anti-citrullinated protein antibody seropositivity, rheumatoid factor seropositivity measurement6106279340106279341Human
597275479GWAS1371553_Hrheumatoid arthritis QTL GWAS1371553 (human)3e-13rheumatoid arthritis6106279340106279341Human
597036935GWAS1133009_Hrheumatoid arthritis QTL GWAS1133009 (human)0.0000001rheumatoid arthritis6106219660106219661Human
597585676GWAS1642536_Heosinophil count QTL GWAS1642536 (human)3e-13eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)6106189027106189028Human
597587978GWAS1644838_Heosinophil count QTL GWAS1644838 (human)2e-15eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)6106189027106189028Human
597270733GWAS1366807_Hrheumatoid arthritis, ACPA-positive rheumatoid arthritis, rheumatoid factor seropositivity measurement QTL GWAS1366807 (human)4e-08rheumatoid arthritis, ACPA-positive rheumatoid arthritis, rheumatoid factor seropositivity measurement6106228595106228596Human
597267468GWAS1363542_Hrheumatoid arthritis QTL GWAS1363542 (human)3e-08rheumatoid arthritis6106228595106228596Human
597205455GWAS1301529_Hrheumatoid arthritis QTL GWAS1301529 (human)4e-09rheumatoid arthritis6106228595106228596Human
597586564GWAS1643424_Heosinophil count QTL GWAS1643424 (human)7e-13eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)6106189027106189028Human
597595073GWAS1651933_Heosinophil count QTL GWAS1651933 (human)5e-26eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)6106189027106189028Human
597118068GWAS1214142_Hsystemic lupus erythematosus QTL GWAS1214142 (human)6e-15systemic lupus erythematosus6106220119106220120Human
597235965GWAS1332039_Hmultiple myeloma QTL GWAS1332039 (human)0.000002multiple myeloma6106219660106219661Human
597596342GWAS1653202_Heosinophil count QTL GWAS1653202 (human)3e-26eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)6106189027106189028Human
1298426BFD3_HBody fluid distribution QTL 3 (human)2.790.01Body fluid distributionimpedance ratio684873647110873647Human
406939434GWAS588410_Heosinophil percentage of leukocytes QTL GWAS588410 (human)2e-14eosinophil quantity (VT:0002602)blood eosinophil count to total leukocyte count ratio (CMO:0000369)6106207543106207544Human
597226675GWAS1322749_Hasthma, age at onset QTL GWAS1322749 (human)0.0000003asthma, age at onset6106219660106219661Human
597579250GWAS1636110_Heosinophil count QTL GWAS1636110 (human)4e-11eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)6106307720106307721Human
597023931GWAS1120005_Hallergic disease QTL GWAS1120005 (human)4e-11allergic disease6106219660106219661Human
597076601GWAS1172675_Hmultiple myeloma QTL GWAS1172675 (human)9e-15multiple myeloma6106219660106219661Human
597052089GWAS1148163_Heosinophil count QTL GWAS1148163 (human)4e-15eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)6106219660106219661Human
597277750GWAS1373824_Hrheumatoid arthritis, anti-citrullinated protein antibody seropositivity, rheumatoid factor seropositivity measurement QTL GWAS1373824 (human)4e-09rheumatoid arthritis, anti-citrullinated protein antibody seropositivity, rheumatoid factor seropositivity measurement6106279340106279341Human
597051556GWAS1147630_Heosinophil count QTL GWAS1147630 (human)1e-14eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)6106207543106207544Human
597047780GWAS1143854_Hchildhood onset asthma QTL GWAS1143854 (human)2e-09childhood onset asthma6106219660106219661Human
407101872GWAS750848_Heosinophil count QTL GWAS750848 (human)2e-11eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)6106279340106279341Human
597101859GWAS1197933_Hsystemic scleroderma QTL GWAS1197933 (human)3e-09systemic scleroderma6106286165106286166Human
597593832GWAS1650692_Heosinophil count QTL GWAS1650692 (human)1e-31eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)6106189027106189028Human
596962339GWAS1081858_Hmultiple myeloma QTL GWAS1081858 (human)2e-16multiple myeloma6106189027106189028Human
597316589GWAS1412663_Hwhite matter lesion progression measurement QTL GWAS1412663 (human)0.0000008central nervous system integrity trait (VT:0010772)6106194217106194218Human
597019618GWAS1115692_Hsystemic scleroderma QTL GWAS1115692 (human)4e-08systemic scleroderma6106207742106207743Human
406975158GWAS624134_Hsystemic scleroderma, systemic lupus erythematosus QTL GWAS624134 (human)0.0000005systemic scleroderma, systemic lupus erythematosus6106237320106237321Human
597305453GWAS1401527_Htotal blood protein measurement QTL GWAS1401527 (human)6e-21total blood protein measurementblood protein measurement (CMO:0000028)6106250177106250178Human
597113065GWAS1209139_Hsystemic lupus erythematosus QTL GWAS1209139 (human)4e-15systemic lupus erythematosus6106207742106207743Human

Markers in Region
WI-20363  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376106,633,898 - 106,634,147UniSTSGRCh37
Build 366106,740,591 - 106,740,840RGDNCBI36
Celera6107,255,451 - 107,255,700RGD
Cytogenetic Map6q21UniSTS
HuRef6104,080,921 - 104,081,170UniSTS
GeneMap99-GB4 RH Map6458.81UniSTS
Whitehead-RH Map6680.6UniSTS
NCBI RH Map61396.9UniSTS
RH93335  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376106,633,635 - 106,633,719UniSTSGRCh37
Build 366106,740,328 - 106,740,412RGDNCBI36
Celera6107,255,188 - 107,255,272RGD
Cytogenetic Map6q21UniSTS
HuRef6104,080,658 - 104,080,742UniSTS
GeneMap99-GB4 RH Map6462.31UniSTS
RH78069  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376106,632,457 - 106,632,604UniSTSGRCh37
Build 366106,739,150 - 106,739,297RGDNCBI36
Celera6107,254,010 - 107,254,157RGD
Cytogenetic Map6q21UniSTS
HuRef6104,079,480 - 104,079,627UniSTS
GeneMap99-GB4 RH Map6462.52UniSTS
STS-N94345  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376106,633,652 - 106,633,730UniSTSGRCh37
Build 366106,740,345 - 106,740,423RGDNCBI36
Celera6107,255,205 - 107,255,283RGD
Cytogenetic Map6q21UniSTS
HuRef6104,080,675 - 104,080,753UniSTS
GeneMap99-GB4 RH Map6458.6UniSTS
EST6B12  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376106,633,863 - 106,634,065UniSTSGRCh37
Build 366106,740,556 - 106,740,758RGDNCBI36
Celera6107,255,416 - 107,255,618RGD
HuRef6104,080,886 - 104,081,088UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2439 2788 2253 4974 1726 2351 6 624 1951 465 2270 7306 6472 53 3734 1 852 1744 1617 175 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001286106 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001286107 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001286108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001286111 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_004849 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_104402 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_104403 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024446590 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047419573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047419574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054356849 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054356850 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054356851 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001743757 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF293841 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK001899 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK299577 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK315800 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL022067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL133509 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL138917 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC002699 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC093011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM831472 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP297166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX537904 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR749386 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU283338 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU283339 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HY168998 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ918353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ918354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ924061 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KT585268 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y11588 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENST00000343245   ⟹   ENSP00000343313
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl6106,184,476 - 106,325,417 (-)Ensembl
Ensembl Acc Id: ENST00000360666   ⟹   ENSP00000353884
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl6106,184,476 - 106,325,657 (-)Ensembl
Ensembl Acc Id: ENST00000369070   ⟹   ENSP00000358066
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl6106,184,476 - 106,325,791 (-)Ensembl
Ensembl Acc Id: ENST00000369076   ⟹   ENSP00000358072
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl6106,184,476 - 106,325,760 (-)Ensembl
Ensembl Acc Id: ENST00000475645
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl6106,184,476 - 106,202,429 (-)Ensembl
Ensembl Acc Id: ENST00000476518
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl6106,201,746 - 106,279,823 (-)Ensembl
Ensembl Acc Id: ENST00000613993   ⟹   ENSP00000483135
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl6106,186,540 - 106,316,208 (-)Ensembl
Ensembl Acc Id: ENST00000635758   ⟹   ENSP00000490493
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl6106,184,476 - 106,325,738 (-)Ensembl
Ensembl Acc Id: ENST00000636335   ⟹   ENSP00000490221
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl6106,046,571 - 106,325,678 (-)Ensembl
Ensembl Acc Id: ENST00000636437   ⟹   ENSP00000490376
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl6106,045,423 - 106,325,762 (-)Ensembl
Ensembl Acc Id: ENST00000646025   ⟹   ENSP00000495958
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl6106,185,942 - 106,325,791 (-)Ensembl
RefSeq Acc Id: NM_001286106   ⟹   NP_001273035
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386106,184,476 - 106,325,437 (-)NCBI
HuRef6104,079,374 - 104,220,613 (-)NCBI
CHM1_16106,894,762 - 107,035,787 (-)NCBI
T2T-CHM13v2.06107,360,315 - 107,501,599 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001286107   ⟹   NP_001273036
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386106,184,476 - 106,325,760 (-)NCBI
HuRef6104,079,374 - 104,220,613 (-)NCBI
CHM1_16106,894,762 - 107,036,172 (-)NCBI
T2T-CHM13v2.06107,360,315 - 107,501,922 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001286108   ⟹   NP_001273037
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386106,184,476 - 106,325,760 (-)NCBI
HuRef6104,079,374 - 104,220,613 (-)NCBI
CHM1_16106,894,762 - 107,036,172 (-)NCBI
T2T-CHM13v2.06107,360,315 - 107,501,922 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001286111   ⟹   NP_001273040
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386106,184,476 - 106,325,760 (-)NCBI
HuRef6104,079,374 - 104,220,613 (-)NCBI
CHM1_16106,894,762 - 107,036,172 (-)NCBI
T2T-CHM13v2.06107,360,315 - 107,501,922 (-)NCBI
Sequence:
RefSeq Acc Id: NM_004849   ⟹   NP_004840
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386106,184,476 - 106,325,760 (-)NCBI
GRCh376106,632,351 - 106,773,695 (-)NCBI
Build 366106,739,045 - 106,880,388 (-)NCBI Archive
HuRef6104,079,374 - 104,220,613 (-)NCBI
CHM1_16106,894,762 - 107,036,172 (-)NCBI
T2T-CHM13v2.06107,360,315 - 107,501,922 (-)NCBI
Sequence:
RefSeq Acc Id: NR_104402
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386106,184,476 - 106,316,266 (-)NCBI
HuRef6104,079,374 - 104,220,613 (-)NCBI
CHM1_16106,894,762 - 107,026,618 (-)NCBI
T2T-CHM13v2.06107,360,315 - 107,492,426 (-)NCBI
Sequence:
RefSeq Acc Id: NR_104403
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386106,184,476 - 106,316,266 (-)NCBI
HuRef6104,079,374 - 104,220,613 (-)NCBI
CHM1_16106,894,762 - 107,026,618 (-)NCBI
T2T-CHM13v2.06107,360,315 - 107,492,426 (-)NCBI
Sequence:
RefSeq Acc Id: XM_024446590   ⟹   XP_024302358
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386106,184,476 - 106,325,437 (-)NCBI
Sequence:
RefSeq Acc Id: XM_047419573   ⟹   XP_047275529
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386106,217,464 - 106,325,760 (-)NCBI
RefSeq Acc Id: XM_047419574   ⟹   XP_047275530
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386106,184,476 - 106,280,837 (-)NCBI
RefSeq Acc Id: XM_054356849   ⟹   XP_054212824
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.06107,393,329 - 107,501,922 (-)NCBI
RefSeq Acc Id: XM_054356850   ⟹   XP_054212825
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.06107,360,315 - 107,501,599 (-)NCBI
RefSeq Acc Id: XM_054356851   ⟹   XP_054212826
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.06107,360,315 - 107,457,004 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001273035 (Get FASTA)   NCBI Sequence Viewer  
  NP_001273036 (Get FASTA)   NCBI Sequence Viewer  
  NP_001273037 (Get FASTA)   NCBI Sequence Viewer  
  NP_001273040 (Get FASTA)   NCBI Sequence Viewer  
  NP_004840 (Get FASTA)   NCBI Sequence Viewer  
  XP_024302358 (Get FASTA)   NCBI Sequence Viewer  
  XP_047275529 (Get FASTA)   NCBI Sequence Viewer  
  XP_047275530 (Get FASTA)   NCBI Sequence Viewer  
  XP_054212824 (Get FASTA)   NCBI Sequence Viewer  
  XP_054212825 (Get FASTA)   NCBI Sequence Viewer  
  XP_054212826 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAG44955 (Get FASTA)   NCBI Sequence Viewer  
  AAH02699 (Get FASTA)   NCBI Sequence Viewer  
  AAH93011 (Get FASTA)   NCBI Sequence Viewer  
  ABX79918 (Get FASTA)   NCBI Sequence Viewer  
  AGC52701 (Get FASTA)   NCBI Sequence Viewer  
  AGC52702 (Get FASTA)   NCBI Sequence Viewer  
  AGC52703 (Get FASTA)   NCBI Sequence Viewer  
  BAG50990 (Get FASTA)   NCBI Sequence Viewer  
  BAH13072 (Get FASTA)   NCBI Sequence Viewer  
  CAA72327 (Get FASTA)   NCBI Sequence Viewer  
  CAD97890 (Get FASTA)   NCBI Sequence Viewer  
  CAH18236 (Get FASTA)   NCBI Sequence Viewer  
  EAW48414 (Get FASTA)   NCBI Sequence Viewer  
  EAW48415 (Get FASTA)   NCBI Sequence Viewer  
  EAW48416 (Get FASTA)   NCBI Sequence Viewer  
  EAW48417 (Get FASTA)   NCBI Sequence Viewer  
  EAW48418 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000343313
  ENSP00000343313.3
  ENSP00000353884
  ENSP00000353884.4
  ENSP00000358066.2
  ENSP00000358072
  ENSP00000358072.3
  ENSP00000483135.1
  ENSP00000490221.1
  ENSP00000490376.1
  ENSP00000490493
  ENSP00000490493.1
  ENSP00000495958
  ENSP00000495958.1
GenBank Protein Q9H1Y0 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_004840   ⟸   NM_004849
- Peptide Label: isoform a
- UniProtKB: Q9H2B8 (UniProtKB/Swiss-Prot),   Q68DI4 (UniProtKB/Swiss-Prot),   Q5JVR2 (UniProtKB/Swiss-Prot),   O60875 (UniProtKB/Swiss-Prot),   Q9HCZ7 (UniProtKB/Swiss-Prot),   Q9H1Y0 (UniProtKB/Swiss-Prot),   A9UGY9 (UniProtKB/TrEMBL),   B3KMH8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001273040   ⟸   NM_001286111
- Peptide Label: isoform d
- UniProtKB: Q7Z3H3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001273036   ⟸   NM_001286107
- Peptide Label: isoform b
- UniProtKB: B7Z5Y6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001273037   ⟸   NM_001286108
- Peptide Label: isoform c
- UniProtKB: Q9H1Y0 (UniProtKB/Swiss-Prot),   Q7Z3H3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001273035   ⟸   NM_001286106
- Peptide Label: isoform a
- UniProtKB: Q9H2B8 (UniProtKB/Swiss-Prot),   Q68DI4 (UniProtKB/Swiss-Prot),   Q5JVR2 (UniProtKB/Swiss-Prot),   O60875 (UniProtKB/Swiss-Prot),   Q9HCZ7 (UniProtKB/Swiss-Prot),   Q9H1Y0 (UniProtKB/Swiss-Prot),   A9UGY9 (UniProtKB/TrEMBL),   B3KMH8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_024302358   ⟸   XM_024446590
- Peptide Label: isoform X2
- UniProtKB: B7Z5Y6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSP00000490493   ⟸   ENST00000635758
Ensembl Acc Id: ENSP00000490376   ⟸   ENST00000636437
Ensembl Acc Id: ENSP00000490221   ⟸   ENST00000636335
Ensembl Acc Id: ENSP00000353884   ⟸   ENST00000360666
Ensembl Acc Id: ENSP00000483135   ⟸   ENST00000613993
Ensembl Acc Id: ENSP00000358072   ⟸   ENST00000369076
Ensembl Acc Id: ENSP00000358066   ⟸   ENST00000369070
Ensembl Acc Id: ENSP00000495958   ⟸   ENST00000646025
Ensembl Acc Id: ENSP00000343313   ⟸   ENST00000343245
RefSeq Acc Id: XP_047275530   ⟸   XM_047419574
- Peptide Label: isoform X3
- UniProtKB: B7Z5Y6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_047275529   ⟸   XM_047419573
- Peptide Label: isoform X1
- UniProtKB: A0A2R8Y718 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054212825   ⟸   XM_054356850
- Peptide Label: isoform X2
- UniProtKB: B7Z5Y6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054212826   ⟸   XM_054356851
- Peptide Label: isoform X3
- UniProtKB: B7Z5Y6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054212824   ⟸   XM_054356849
- Peptide Label: isoform X1
- UniProtKB: A0A2R8Y718 (UniProtKB/TrEMBL)
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9H1Y0-F1-model_v2 AlphaFold Q9H1Y0 1-275 view protein structure

Promoters
RGD ID:7208797
Promoter ID:EPDNEW_H10145
Type:initiation region
Name:ATG5_3
Description:autophagy related 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H10146  EPDNEW_H10147  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh386106,325,423 - 106,325,483EPDNEW
RGD ID:7208801
Promoter ID:EPDNEW_H10146
Type:initiation region
Name:ATG5_1
Description:autophagy related 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H10145  EPDNEW_H10147  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh386106,325,630 - 106,325,690EPDNEW
RGD ID:7208803
Promoter ID:EPDNEW_H10147
Type:initiation region
Name:ATG5_2
Description:autophagy related 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H10145  EPDNEW_H10146  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh386106,325,747 - 106,325,807EPDNEW
RGD ID:6803943
Promoter ID:HG_KWN:54495
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000343245,   OTTHUMT00000043476,   UC003PRG.1,   UC010KDB.1,   UC010KDC.1
Position:
Human AssemblyChrPosition (strand)Source
Build 366106,880,049 - 106,880,549 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:589 AgrOrtholog
COSMIC ATG5 COSMIC
Ensembl Genes ENSG00000057663 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000343245 ENTREZGENE
  ENST00000343245.7 UniProtKB/Swiss-Prot
  ENST00000360666 ENTREZGENE
  ENST00000360666.6 UniProtKB/TrEMBL
  ENST00000369070 ENTREZGENE
  ENST00000369070.5 UniProtKB/TrEMBL
  ENST00000369076 ENTREZGENE
  ENST00000369076.8 UniProtKB/Swiss-Prot
  ENST00000613993.1 UniProtKB/TrEMBL
  ENST00000635758 ENTREZGENE
  ENST00000635758.2 UniProtKB/Swiss-Prot
  ENST00000636335.1 UniProtKB/TrEMBL
  ENST00000636437.1 UniProtKB/TrEMBL
  ENST00000646025 ENTREZGENE
  ENST00000646025.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.246.190 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.10.20.620 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000057663 GTEx
HGNC ID HGNC:589 ENTREZGENE
Human Proteome Map ATG5 Human Proteome Map
InterPro Atg5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATG5_HBR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Atg5_HR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATG5_UblA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Atg5_UblA_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATG5_UblB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:9474 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 9474 ENTREZGENE
OMIM 604261 OMIM
PANTHER AUTOPHAGY PROTEIN 5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR13040 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam APG5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATG5_HBR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATG5_UblA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA24880 PharmGKB
UniProt A0A1B0GUS1_HUMAN UniProtKB/TrEMBL
  A0A1B0GV54_HUMAN UniProtKB/TrEMBL
  A0A2R8Y718 ENTREZGENE, UniProtKB/TrEMBL
  A9UGY9 ENTREZGENE, UniProtKB/TrEMBL
  ATG5_HUMAN UniProtKB/Swiss-Prot
  B3KMH8 ENTREZGENE, UniProtKB/TrEMBL
  B7Z5Y6 ENTREZGENE, UniProtKB/TrEMBL
  L7UMD8_HUMAN UniProtKB/TrEMBL
  L7UQJ2_HUMAN UniProtKB/TrEMBL
  O60875 ENTREZGENE
  Q5JVR2 ENTREZGENE
  Q68DI4 ENTREZGENE
  Q7Z3H3 ENTREZGENE, UniProtKB/TrEMBL
  Q9H1Y0 ENTREZGENE
  Q9H2B8 ENTREZGENE
  Q9HCZ7 ENTREZGENE
UniProt Secondary O60875 UniProtKB/Swiss-Prot
  Q5JVR2 UniProtKB/Swiss-Prot
  Q68DI4 UniProtKB/Swiss-Prot
  Q9H2B8 UniProtKB/Swiss-Prot
  Q9HCZ7 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-06-12 ATG5  autophagy related 5  ATG5  ATG5 autophagy related 5 homolog (S. cerevisiae)  Symbol and/or name change 5135510 APPROVED