BPI (bactericidal permeability increasing protein) - Rat Genome Database

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Gene: BPI (bactericidal permeability increasing protein) Homo sapiens
Analyze
Symbol: BPI
Name: bactericidal permeability increasing protein
RGD ID: 1352137
HGNC Page HGNC:1095
Description: Enables lipopolysaccharide binding activity. Involved in negative regulation of cytokine production and negative regulation of macrophage activation. Located in cytoplasmic stress granule. Implicated in Crohn's disease. Biomarker of severe acute respiratory syndrome.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: bactericidal permeability-increasing protein; BPI fold containing family D, member 1; BPIFD1; CAP 57; rBPI; recombinant BPI holoprotein, rBPI
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382038,304,156 - 38,337,505 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2038,260,141 - 38,337,505 (+)EnsemblGRCh38hg38GRCh38
GRCh372036,932,558 - 36,965,907 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362036,365,966 - 36,399,319 (+)NCBINCBI36Build 36hg18NCBI36
Build 342036,365,998 - 36,399,319NCBI
Celera2033,641,353 - 33,674,701 (+)NCBICelera
Cytogenetic Map20q11.23NCBI
HuRef2033,669,787 - 33,677,356 (+)NCBIHuRef
HuRef2033,682,342 - 33,700,820 (+)NCBIHuRef
CHM1_12036,836,236 - 36,869,681 (+)NCBICHM1_1
T2T-CHM13v2.02040,030,315 - 40,063,822 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. A polymorphism of the bactericidal/permeability increasing protein (BPI) gene is associated with Crohn's disease. Klein W, etal., J Clin Gastroenterol. 2005 Apr;39(4):282-3.
3. Elucidating the molecular physiopathology of acute respiratory distress syndrome in severe acute respiratory syndrome patients. Kong SL, etal., Virus Res. 2009 Nov;145(2):260-9. Epub 2009 Jul 25.
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1937776   PMID:2501794   PMID:2722846   PMID:3667613   PMID:7517398   PMID:8330906   PMID:8409400   PMID:8432532   PMID:9188532   PMID:9240454   PMID:9616176   PMID:11373419  
PMID:11420435   PMID:11780052   PMID:11891303   PMID:12477932   PMID:12521224   PMID:12710851   PMID:12738651   PMID:12784398   PMID:12913926   PMID:14623259   PMID:15009116   PMID:15342556  
PMID:15590754   PMID:16282362   PMID:16380496   PMID:16861658   PMID:16893388   PMID:17012258   PMID:17239348   PMID:17483073   PMID:17488601   PMID:17675509   PMID:17678885   PMID:17898994  
PMID:19056867   PMID:19275920   PMID:19423540   PMID:19692168   PMID:19702878   PMID:19913121   PMID:20174761   PMID:20237496   PMID:20406964   PMID:20412700   PMID:20438785   PMID:20463618  
PMID:20541026   PMID:20628086   PMID:20889312   PMID:21272798   PMID:21463973   PMID:21787345   PMID:21873635   PMID:22409502   PMID:23346184   PMID:23376485   PMID:23626859   PMID:26107902  
PMID:26228368   PMID:28035462   PMID:30581431   PMID:31106488   PMID:31586073   PMID:32705592   PMID:33961781   PMID:34815797   PMID:35256949   PMID:35271311   PMID:36672756  


Genomics

Comparative Map Data
BPI
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382038,304,156 - 38,337,505 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2038,260,141 - 38,337,505 (+)EnsemblGRCh38hg38GRCh38
GRCh372036,932,558 - 36,965,907 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362036,365,966 - 36,399,319 (+)NCBINCBI36Build 36hg18NCBI36
Build 342036,365,998 - 36,399,319NCBI
Celera2033,641,353 - 33,674,701 (+)NCBICelera
Cytogenetic Map20q11.23NCBI
HuRef2033,669,787 - 33,677,356 (+)NCBIHuRef
HuRef2033,682,342 - 33,700,820 (+)NCBIHuRef
CHM1_12036,836,236 - 36,869,681 (+)NCBICHM1_1
T2T-CHM13v2.02040,030,315 - 40,063,822 (+)NCBIT2T-CHM13v2.0
Bpi
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392158,099,983 - 158,126,453 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2158,100,014 - 158,126,451 (+)EnsemblGRCm39 Ensembl
GRCm382158,258,063 - 158,284,533 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2158,258,094 - 158,284,531 (+)EnsemblGRCm38mm10GRCm38
MGSCv372158,083,977 - 158,110,267 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362157,949,682 - 157,975,972 (+)NCBIMGSCv36mm8
Celera2164,202,890 - 164,229,087 (+)NCBICelera
Cytogenetic Map2H1NCBI
cM Map278.72NCBI
Bpi
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83167,329,513 - 167,356,217 (+)NCBIGRCr8
mRatBN7.23146,909,626 - 146,936,487 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3146,909,629 - 146,936,221 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3150,734,952 - 150,761,530 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03159,234,289 - 159,260,817 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03156,975,825 - 157,002,320 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03154,741,627 - 154,768,584 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3154,741,631 - 154,768,640 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03160,837,585 - 160,864,610 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43148,970,965 - 148,998,795 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13148,876,873 - 148,904,703 (+)NCBI
Celera3145,610,965 - 145,637,569 (+)NCBICelera
Cytogenetic Map3q42NCBI
Bpi
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544518,391,215 - 18,427,980 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544518,393,854 - 18,433,948 (-)NCBIChiLan1.0ChiLan1.0
BPI
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22144,029,197 - 44,061,897 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12044,022,295 - 44,054,995 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02034,633,243 - 34,661,171 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12035,739,700 - 35,771,910 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2035,739,700 - 35,771,910 (+)Ensemblpanpan1.1panPan2
BPI
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12426,772,410 - 26,800,763 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2426,767,746 - 26,800,762 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2426,418,210 - 26,446,528 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02427,468,496 - 27,496,799 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2427,470,021 - 27,496,805 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12426,742,847 - 26,771,163 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02426,850,759 - 26,879,003 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02427,339,168 - 27,367,492 (+)NCBIUU_Cfam_GSD_1.0
Bpi
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640175,679,861 - 175,706,205 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365613,043,578 - 3,069,689 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365613,043,520 - 3,069,680 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BPI
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1741,344,939 - 41,392,100 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11741,344,878 - 41,392,103 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21746,783,441 - 46,831,210 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BPI
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1225,416,154 - 25,450,474 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl225,416,463 - 25,449,958 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605074,256,072 - 74,290,275 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bpi
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248421,339,603 - 1,360,097 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248421,339,309 - 1,363,265 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in BPI
60 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 20q11.22-12(chr20:34541747-39663219)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052766]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052766]|See cases [RCV000052766] Chr20:34541747..39663219 [GRCh38]
Chr20:33129551..38291861 [GRCh37]
Chr20:32593212..37725275 [NCBI36]
Chr20:20q11.22-12		 pathogenic
GRCh38/hg38 20q11.22-13.11(chr20:34249453-43359749)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053002]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053002]|See cases [RCV000053002] Chr20:34249453..43359749 [GRCh38]
Chr20:32837259..41988389 [GRCh37]
Chr20:32300920..41421803 [NCBI36]
Chr20:20q11.22-13.11		 pathogenic
GRCh38/hg38 20p12.2-q12(chr20:9811433-39316956)x3 copy number gain See cases [RCV000052999] Chr20:9811433..39316956 [GRCh38]
Chr20:9792081..37945599 [GRCh37]
Chr20:9740081..37379013 [NCBI36]
Chr20:20p12.2-q12		 pathogenic
NM_001725.2(BPI):c.769-327G>A single nucleotide variant Lung cancer [RCV000101552] Chr20:38323543 [GRCh38]
Chr20:36951945 [GRCh37]
Chr20:20q11.23		 uncertain significance
GRCh38/hg38 20p13-q13.33(chr20:99557-64277321)x3 copy number gain See cases [RCV000135859] Chr20:99557..64277321 [GRCh38]
Chr20:80198..62908674 [GRCh37]
Chr20:28198..62379118 [NCBI36]
Chr20:20p13-q13.33		 pathogenic
GRCh38/hg38 20q11.22-13.12(chr20:35237946-47631818)x1 copy number loss See cases [RCV000140816] Chr20:35237946..47631818 [GRCh38]
Chr20:33825749..46260562 [GRCh37]
Chr20:33289165..45693969 [NCBI36]
Chr20:20q11.22-13.12		 pathogenic
GRCh38/hg38 20q11.23(chr20:38280050-38320156)x1 copy number loss See cases [RCV000141030] Chr20:38280050..38320156 [GRCh38]
Chr20:36908452..36948558 [GRCh37]
Chr20:36341866..36381972 [NCBI36]
Chr20:20q11.23		 benign
NM_001725.3(BPI):c.933+6G>A single nucleotide variant not specified [RCV000203068] Chr20:38324052 [GRCh38]
Chr20:36952454 [GRCh37]
Chr20:20q11.23		 uncertain significance
GRCh37/hg19 20q11.23(chr20:36905828-36972896) copy number loss Abnormal esophagus morphology [RCV000416732] Chr20:36905828..36972896 [GRCh37]
Chr20:20q11.23		 benign
NM_001725.3(BPI):c.534G>C (p.Val178=) single nucleotide variant not provided [RCV004717597]|not specified [RCV000454634] Chr20:38310650 [GRCh38]
Chr20:36939052 [GRCh37]
Chr20:20q11.23		 benign
NM_001725.3(BPI):c.575C>T (p.Ala192Val) single nucleotide variant not provided [RCV004717598]|not specified [RCV000455289] Chr20:38311912 [GRCh38]
Chr20:36940314 [GRCh37]
Chr20:20q11.23		 benign
NM_001725.3(BPI):c.35C>T (p.Ala12Val) single nucleotide variant not provided [RCV004717595]|not specified [RCV000455313] Chr20:38304258 [GRCh38]
Chr20:36932660 [GRCh37]
Chr20:20q11.23		 benign
NM_001725.3(BPI):c.51G>C (p.Leu17=) single nucleotide variant not provided [RCV004717596]|not specified [RCV000456086] Chr20:38304274 [GRCh38]
Chr20:36932676 [GRCh37]
Chr20:20q11.23		 benign
NM_001725.3(BPI):c.634G>A (p.Glu212Lys) single nucleotide variant not provided [RCV004717599]|not specified [RCV000456105] Chr20:38318446 [GRCh38]
Chr20:36946848 [GRCh37]
Chr20:20q11.23		 benign
GRCh37/hg19 20p13-q13.33(chr20:61569-62915555)x3 copy number gain See cases [RCV000510832] Chr20:61569..62915555 [GRCh37]
Chr20:20p13-q13.33		 pathogenic
NM_001725.3(BPI):c.410G>C (p.Gly137Ala) single nucleotide variant not specified [RCV004332589] Chr20:38310526 [GRCh38]
Chr20:36938928 [GRCh37]
Chr20:20q11.23		 uncertain significance
GRCh37/hg19 20p13-q13.33(chr20:61569-62915555) copy number gain See cases [RCV000512450] Chr20:61569..62915555 [GRCh37]
Chr20:20p13-q13.33		 pathogenic
GRCh37/hg19 20q11.23(chr20:36960905-37061017)x1 copy number loss not provided [RCV000684101] Chr20:36960905..37061017 [GRCh37]
Chr20:20q11.23		 likely benign
GRCh37/hg19 20p13-q13.33(chr20:63244-62961294)x3 copy number gain not provided [RCV000741059] Chr20:63244..62961294 [GRCh37]
Chr20:20p13-q13.33		 pathogenic
GRCh37/hg19 20q11.23(chr20:36911367-36971709)x1 copy number loss not provided [RCV000741191] Chr20:36911367..36971709 [GRCh37]
Chr20:20q11.23		 benign
GRCh37/hg19 20p13-q13.33(chr20:63244-62912463)x3 copy number gain not provided [RCV000741057] Chr20:63244..62912463 [GRCh37]
Chr20:20p13-q13.33		 pathogenic
GRCh37/hg19 20p13-q13.33(chr20:63244-62948788)x3 copy number gain not provided [RCV000741058] Chr20:63244..62948788 [GRCh37]
Chr20:20p13-q13.33		 pathogenic
NM_001725.3(BPI):c.453G>A (p.Thr151=) single nucleotide variant not provided [RCV000943300] Chr20:38310569 [GRCh38]
Chr20:36938971 [GRCh37]
Chr20:20q11.23		 likely benign
NM_001725.3(BPI):c.406G>C (p.Glu136Gln) single nucleotide variant not provided [RCV000968406] Chr20:38310522 [GRCh38]
Chr20:36938924 [GRCh37]
Chr20:20q11.23		 benign
NM_001725.3(BPI):c.22G>A (p.Ala8Thr) single nucleotide variant not provided [RCV000967800] Chr20:38304245 [GRCh38]
Chr20:36932647 [GRCh37]
Chr20:20q11.23		 benign
NM_001725.3(BPI):c.23C>T (p.Ala8Val) single nucleotide variant not provided [RCV000970370] Chr20:38304246 [GRCh38]
Chr20:36932648 [GRCh37]
Chr20:20q11.23		 benign
NM_001725.3(BPI):c.664+7G>T single nucleotide variant not provided [RCV000882274] Chr20:38318483 [GRCh38]
Chr20:36946885 [GRCh37]
Chr20:20q11.23		 benign
NM_001725.3(BPI):c.1339A>G (p.Lys447Glu) single nucleotide variant not provided [RCV000901831] Chr20:38335600 [GRCh38]
Chr20:36964002 [GRCh37]
Chr20:20q11.23		 likely benign
NM_001725.3(BPI):c.997G>A (p.Ala333Thr) single nucleotide variant not provided [RCV000879221] Chr20:38326268 [GRCh38]
Chr20:36954670 [GRCh37]
Chr20:20q11.23		 likely benign
NM_001725.3(BPI):c.812T>C (p.Met271Thr) single nucleotide variant not specified [RCV004291195] Chr20:38323925 [GRCh38]
Chr20:36952327 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_001725.3(BPI):c.345C>T (p.Ser115=) single nucleotide variant not provided [RCV000954783] Chr20:38309029 [GRCh38]
Chr20:36937431 [GRCh37]
Chr20:20q11.23		 benign
NM_001725.3(BPI):c.1074C>T (p.Thr358=) single nucleotide variant not provided [RCV000943301] Chr20:38326345 [GRCh38]
Chr20:36954747 [GRCh37]
Chr20:20q11.23		 likely benign
NM_001725.3(BPI):c.256C>T (p.Arg86Cys) single nucleotide variant not provided [RCV000958037] Chr20:38308940 [GRCh38]
Chr20:36937342 [GRCh37]
Chr20:20q11.23		 benign
Single allele deletion Focal-onset seizure [RCV001004039] Chr20:34980430..46806549 [GRCh37]
Chr20:20q11.23-13.13		 likely pathogenic
NM_001725.3(BPI):c.385G>A (p.Gly129Ser) single nucleotide variant not specified [RCV004292192] Chr20:38310501 [GRCh38]
Chr20:36938903 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_001725.3(BPI):c.-6G>A single nucleotide variant not specified [RCV004195218] Chr20:38304218 [GRCh38]
Chr20:36932620 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_001725.3(BPI):c.834C>G (p.Asp278Glu) single nucleotide variant not specified [RCV004177077] Chr20:38323947 [GRCh38]
Chr20:36952349 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_001725.3(BPI):c.113A>G (p.Gln38Arg) single nucleotide variant not specified [RCV004075955] Chr20:38304336 [GRCh38]
Chr20:36932738 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_001725.3(BPI):c.545T>C (p.Ile182Thr) single nucleotide variant not specified [RCV004119486] Chr20:38311882 [GRCh38]
Chr20:36940284 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_001725.3(BPI):c.327C>G (p.Asn109Lys) single nucleotide variant not specified [RCV004096001] Chr20:38309011 [GRCh38]
Chr20:36937413 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_001725.3(BPI):c.661C>A (p.Pro221Thr) single nucleotide variant not specified [RCV004185085] Chr20:38318473 [GRCh38]
Chr20:36946875 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_001725.3(BPI):c.1147T>G (p.Phe383Val) single nucleotide variant not specified [RCV004148624] Chr20:38326418 [GRCh38]
Chr20:36954820 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_001725.3(BPI):c.923G>C (p.Arg308Thr) single nucleotide variant not specified [RCV004179560] Chr20:38324036 [GRCh38]
Chr20:36952438 [GRCh37]
Chr20:20q11.23		 likely benign
NM_001725.3(BPI):c.962C>A (p.Thr321Lys) single nucleotide variant not specified [RCV004209271] Chr20:38324802 [GRCh38]
Chr20:36953204 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_001725.3(BPI):c.77C>T (p.Ala26Val) single nucleotide variant not specified [RCV004078769] Chr20:38304300 [GRCh38]
Chr20:36932702 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_001725.3(BPI):c.898G>T (p.Ala300Ser) single nucleotide variant not specified [RCV004074711] Chr20:38324011 [GRCh38]
Chr20:36952413 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_001725.3(BPI):c.1075G>A (p.Gly359Ser) single nucleotide variant not specified [RCV004216852] Chr20:38326346 [GRCh38]
Chr20:36954748 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_001725.3(BPI):c.1393G>A (p.Val465Ile) single nucleotide variant not specified [RCV004253193] Chr20:38335654 [GRCh38]
Chr20:36964056 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_001725.3(BPI):c.623C>T (p.Ser208Phe) single nucleotide variant not specified [RCV004256264] Chr20:38318435 [GRCh38]
Chr20:36946837 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_001725.3(BPI):c.61G>A (p.Gly21Ser) single nucleotide variant not specified [RCV004315616] Chr20:38304284 [GRCh38]
Chr20:36932686 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_001725.3(BPI):c.299A>G (p.Asn100Ser) single nucleotide variant not specified [RCV004300708] Chr20:38308983 [GRCh38]
Chr20:36937385 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_001725.3(BPI):c.1001A>G (p.Lys334Arg) single nucleotide variant not specified [RCV004340874] Chr20:38326272 [GRCh38]
Chr20:36954674 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_001725.3(BPI):c.67G>A (p.Ala23Thr) single nucleotide variant not specified [RCV004350306] Chr20:38304290 [GRCh38]
Chr20:36932692 [GRCh37]
Chr20:20q11.23		 likely benign
NM_001725.3(BPI):c.52G>A (p.Val18Ile) single nucleotide variant not specified [RCV004365517] Chr20:38304275 [GRCh38]
Chr20:36932677 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_001725.3(BPI):c.688G>C (p.Ala230Pro) single nucleotide variant not specified [RCV004358602] Chr20:38320206 [GRCh38]
Chr20:36948608 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_001725.3(BPI):c.5C>A (p.Ala2Asp) single nucleotide variant not specified [RCV004346450] Chr20:38304228 [GRCh38]
Chr20:36932630 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_001725.3(BPI):c.450C>T (p.Pro150=) single nucleotide variant not provided [RCV003440397] Chr20:38310566 [GRCh38]
Chr20:36938968 [GRCh37]
Chr20:20q11.23		 likely benign
NM_001725.3(BPI):c.607G>A (p.Glu203Lys) single nucleotide variant not specified [RCV004434137] Chr20:38318419 [GRCh38]
Chr20:36946821 [GRCh37]
Chr20:20q11.23		 likely benign
NM_001725.3(BPI):c.1417T>A (p.Phe473Ile) single nucleotide variant not specified [RCV004434135] Chr20:38337149 [GRCh38]
Chr20:36965551 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_001725.3(BPI):c.823G>A (p.Ala275Thr) single nucleotide variant not specified [RCV004434139] Chr20:38323936 [GRCh38]
Chr20:36952338 [GRCh37]
Chr20:20q11.23		 likely benign
NM_001725.3(BPI):c.1269C>G (p.Phe423Leu) single nucleotide variant not specified [RCV004434134] Chr20:38331087 [GRCh38]
Chr20:36959489 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_001725.3(BPI):c.395A>C (p.Asp132Ala) single nucleotide variant not specified [RCV004434136] Chr20:38310511 [GRCh38]
Chr20:36938913 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_001725.3(BPI):c.722C>T (p.Ala241Val) single nucleotide variant not specified [RCV004434138] Chr20:38320240 [GRCh38]
Chr20:36948642 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_001725.3(BPI):c.840G>T (p.Met280Ile) single nucleotide variant not specified [RCV004434140] Chr20:38323953 [GRCh38]
Chr20:36952355 [GRCh37]
Chr20:20q11.23		 uncertain significance
NM_001725.3(BPI):c.1438G>A (p.Val480Ile) single nucleotide variant not specified [RCV004602143] Chr20:38337170 [GRCh38]
Chr20:36965572 [GRCh37]
Chr20:20q11.23		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2555
Count of miRNA genes:1067
Interacting mature miRNAs:1304
Transcripts:ENST00000262865, ENST00000417318, ENST00000418004, ENST00000451435, ENST00000479646, ENST00000489039, ENST00000489102, ENST00000490381
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
406951296GWAS600272_Hbactericidal permeability-increasing protein measurement QTL GWAS600272 (human)5e-231neutrophil phagocytosis trait (VT:0002467)203832214838322149Human
407230532GWAS879508_Hresponse to carboplatin QTL GWAS879508 (human)0.000009response to carboplatin203832394038323941Human
407175719GWAS824695_Htumor necrosis factor measurement QTL GWAS824695 (human)8e-15blood tumor necrosis factor amount (VT:0008552)inflammatory exudate tumor necrosis factor level (CMO:0001435)203833268238332683Human
407178752GWAS827728_Hreaction time measurement QTL GWAS827728 (human)0.000009reaction time measurement203830486538304866Human
407231776GWAS880752_Hblood protein measurement QTL GWAS880752 (human)4e-143blood protein measurementblood protein measurement (CMO:0000028)203831118538311186Human
407244078GWAS893054_Hvaline measurement QTL GWAS893054 (human)0.000005valine measurementblood amino acid measurement (CMO:0003730)203831078538310786Human
407290892GWAS939868_Hbactericidal permeability-increasing protein measurement QTL GWAS939868 (human)2e-16neutrophil phagocytosis trait (VT:0002467)203830971938309720Human
406894668GWAS543644_Hbactericidal permeability-increasing protein measurement QTL GWAS543644 (human)7e-64neutrophil phagocytosis trait (VT:0002467)203832053238320533Human
407290890GWAS939866_Hbactericidal permeability-increasing protein measurement QTL GWAS939866 (human)5e-33neutrophil phagocytosis trait (VT:0002467)203832971338329714Human
407290891GWAS939867_Hbactericidal permeability-increasing protein measurement QTL GWAS939867 (human)5e-28neutrophil phagocytosis trait (VT:0002467)203832214838322149Human
407022573GWAS671549_Hmental or behavioural disorder QTL GWAS671549 (human)0.000001mental or behavioural disorder203832943538329436Human
1300007BP29_HBlood pressure QTL 29 (human)Blood pressurehypertension susceptibility203653600562536005Human
407258867GWAS907843_Hbactericidal permeability-increasing protein measurement QTL GWAS907843 (human)1e-31neutrophil phagocytosis trait (VT:0002467)203831191238311913Human
407200146GWAS849122_Hmonocyte count QTL GWAS849122 (human)1e-10monocyte quantity (VT:0000223)blood monocyte count (CMO:0000032)203831887338318874Human
407297278GWAS946254_Hlipopolysaccharide-binding protein measurement QTL GWAS946254 (human)9e-18lipopolysaccharide-binding protein measurement203832527938325280Human
407231774GWAS880750_Hblood protein measurement QTL GWAS880750 (human)4e-13blood protein measurementblood protein measurement (CMO:0000028)203830439638304397Human
407202136GWAS851112_Hblood protein measurement QTL GWAS851112 (human)5e-46blood protein measurementblood protein measurement (CMO:0000028)203831529338315294Human
407323322GWAS972298_Hprotein measurement QTL GWAS972298 (human)1e-08protein measurement203832509338325094Human
407196314GWAS845290_Hmonocyte percentage of leukocytes QTL GWAS845290 (human)7e-15monocyte percentage of leukocytesblood monocyte count to total leukocyte count ratio (CMO:0000374)203832053238320533Human

Markers in Region
stbA2202H1A  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372036,940,363 - 36,940,493UniSTSGRCh37
Build 362036,373,777 - 36,373,907RGDNCBI36
Celera2033,649,164 - 33,649,294RGD
Cytogenetic Map20q11.23UniSTS
HuRef2033,677,378 - 33,677,508UniSTS
D20S1064  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372036,936,441 - 36,936,649UniSTSGRCh37
Build 362036,369,855 - 36,370,063RGDNCBI36
Celera2033,645,242 - 33,645,450RGD
Cytogenetic Map20q11.23UniSTS
HuRef2033,673,676 - 33,673,884UniSTS
Whitehead-RH Map20227.7UniSTS
Whitehead-YAC Contig Map20 UniSTS
SGC32792  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372036,954,699 - 36,954,848UniSTSGRCh37
Build 362036,388,113 - 36,388,262RGDNCBI36
Celera2033,663,495 - 33,663,644RGD
Cytogenetic Map20q11.23UniSTS
GeneMap99-GB4 RH Map20212.87UniSTS
GeneMap99-GB4 RH Map20211.79UniSTS
Whitehead-RH Map20227.7UniSTS
SHGC-12397  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372036,965,617 - 36,965,872UniSTSGRCh37
Build 362036,399,031 - 36,399,286RGDNCBI36
Celera2033,674,413 - 33,674,668RGD
Cytogenetic Map20q11.23UniSTS
HuRef2033,700,532 - 33,700,787UniSTS
Stanford-G3 RH Map202007.0UniSTS
GeneMap99-GB4 RH Map20212.77UniSTS
GeneMap99-GB4 RH Map20212.87UniSTS
Whitehead-RH Map20231.0UniSTS
Whitehead-YAC Contig Map20 UniSTS
NCBI RH Map20345.4UniSTS
GeneMap99-G3 RH Map202040.0UniSTS
BPI_2849  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372036,965,464 - 36,965,968UniSTSGRCh37
Build 362036,398,878 - 36,399,382RGDNCBI36
Celera2033,674,260 - 33,674,764RGD
HuRef2033,700,379 - 33,700,883UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
1181 2240 2481 2191 4299 1590 1987 1 547 1364 392 1710 6190 5776 10 3599 711 1570 1330 157

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_047016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001725 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024451972 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047440393 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047440394 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047440395 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054323896 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054323897 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054323898 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF322588 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI436120 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK296568 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK315328 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL359555 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL391095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL499625 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL583962 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AX713278 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AX746123 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AX752831 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC032230 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC040955 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP306215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471077 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068258 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CQ800679 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ414688 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  J04739 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y14215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y14216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y14217 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y14218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y14219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y14220 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y14221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y14222 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y14223 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y14224 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y14225 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y14226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y14227 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y14228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y14229 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENST00000262865   ⟹   ENSP00000262865
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2038,260,141 - 38,337,413 (+)Ensembl
Ensembl Acc Id: ENST00000417318   ⟹   ENSP00000409833
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2038,317,649 - 38,337,325 (+)Ensembl
Ensembl Acc Id: ENST00000418004   ⟹   ENSP00000520599
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2038,260,149 - 38,337,365 (+)Ensembl
Ensembl Acc Id: ENST00000451435
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2038,260,175 - 38,293,892 (+)Ensembl
Ensembl Acc Id: ENST00000489039
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2038,319,786 - 38,321,808 (+)Ensembl
Ensembl Acc Id: ENST00000489102   ⟹   ENSP00000486976
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2038,317,672 - 38,335,641 (+)Ensembl
Ensembl Acc Id: ENST00000490381
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2038,335,473 - 38,337,261 (+)Ensembl
Ensembl Acc Id: ENST00000642449   ⟹   ENSP00000494528
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2038,304,156 - 38,337,505 (+)Ensembl
Ensembl Acc Id: ENST00000716802   ⟹   ENSP00000520600
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2038,260,289 - 38,337,459 (+)Ensembl
RefSeq Acc Id: NM_001725   ⟹   NP_001716
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382038,304,156 - 38,337,505 (+)NCBI
GRCh372036,932,552 - 36,965,907 (+)NCBI
Build 362036,365,966 - 36,399,319 (+)NCBI Archive
HuRef2033,682,342 - 33,700,820 (+)ENTREZGENE
HuRef2033,669,787 - 33,677,356 (+)NCBI
CHM1_12036,836,236 - 36,869,681 (+)NCBI
T2T-CHM13v2.02040,030,315 - 40,063,822 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024451972   ⟹   XP_024307740
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382038,317,912 - 38,337,505 (+)NCBI
Sequence:
RefSeq Acc Id: XM_047440393   ⟹   XP_047296349
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382038,304,156 - 38,337,505 (+)NCBI
RefSeq Acc Id: XM_047440394   ⟹   XP_047296350
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382038,304,156 - 38,334,493 (+)NCBI
RefSeq Acc Id: XM_047440395   ⟹   XP_047296351
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382038,317,912 - 38,337,505 (+)NCBI
RefSeq Acc Id: XM_054323896   ⟹   XP_054179871
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.02040,030,315 - 40,063,822 (+)NCBI
RefSeq Acc Id: XM_054323897   ⟹   XP_054179872
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.02040,030,315 - 40,060,810 (+)NCBI
RefSeq Acc Id: XM_054323898   ⟹   XP_054179873
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.02040,044,077 - 40,063,822 (+)NCBI
RefSeq Acc Id: NP_001716   ⟸   NM_001725
- Peptide Label: precursor
- UniProtKB: Q9UD65 (UniProtKB/Swiss-Prot),   Q9UCT4 (UniProtKB/Swiss-Prot),   Q9H203 (UniProtKB/Swiss-Prot),   Q9H1M8 (UniProtKB/Swiss-Prot),   Q9H1L2 (UniProtKB/Swiss-Prot),   Q9BYZ9 (UniProtKB/Swiss-Prot),   Q8IW58 (UniProtKB/Swiss-Prot),   Q5JRW0 (UniProtKB/Swiss-Prot),   Q1ZZU8 (UniProtKB/Swiss-Prot),   P17213 (UniProtKB/Swiss-Prot),   B2RCY2 (UniProtKB/Swiss-Prot),   A0A2R8YDF1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_024307740   ⟸   XM_024451972
- Peptide Label: isoform X4
- UniProtKB: H0Y738 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSP00000409833   ⟸   ENST00000417318
Ensembl Acc Id: ENSP00000494528   ⟸   ENST00000642449
Ensembl Acc Id: ENSP00000262865   ⟸   ENST00000262865
Ensembl Acc Id: ENSP00000486976   ⟸   ENST00000489102
RefSeq Acc Id: XP_047296349   ⟸   XM_047440393
- Peptide Label: isoform X1
RefSeq Acc Id: XP_047296350   ⟸   XM_047440394
- Peptide Label: isoform X2
RefSeq Acc Id: XP_047296351   ⟸   XM_047440395
- Peptide Label: isoform X3
RefSeq Acc Id: XP_054179871   ⟸   XM_054323896
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054179872   ⟸   XM_054323897
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054179873   ⟸   XM_054323898
- Peptide Label: isoform X4
Ensembl Acc Id: ENSP00000520600   ⟸   ENST00000716802
Ensembl Acc Id: ENSP00000520599   ⟸   ENST00000418004
Protein Domains
Lipid-binding serum glycoprotein C-terminal   Lipid-binding serum glycoprotein N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P17213-F1-model_v2 AlphaFold P17213 1-487 view protein structure

Promoters
RGD ID:13206911
Promoter ID:EPDNEW_H27036
Type:single initiation site
Name:BPI_3
Description:bactericidal/permeability-increasing protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H27035  EPDNEW_H27037  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh382038,300,200 - 38,300,260EPDNEW
RGD ID:13206913
Promoter ID:EPDNEW_H27037
Type:initiation region
Name:BPI_2
Description:bactericidal/permeability-increasing protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H27035  EPDNEW_H27036  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh382038,304,156 - 38,304,216EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:1095 AgrOrtholog
COSMIC BPI COSMIC
Ensembl Genes ENSG00000101425 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000262865.9 UniProtKB/Swiss-Prot
  ENST00000417318 ENTREZGENE
  ENST00000417318.3 UniProtKB/TrEMBL
  ENST00000418004 ENTREZGENE
  ENST00000489102.2 UniProtKB/TrEMBL
  ENST00000642449 ENTREZGENE
  ENST00000642449.2 UniProtKB/TrEMBL
GTEx ENSG00000101425 GTEx
HGNC ID HGNC:1095 ENTREZGENE
Human Proteome Map BPI Human Proteome Map
InterPro Bactericidal_perm-incr_a/b_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BPI/LBP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BPI/LBP/Plunc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Lipid-bd_serum_glycop_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Lipid-bd_serum_glycop_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Lipid-bd_serum_glycop_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:671 UniProtKB/Swiss-Prot
NCBI Gene 671 ENTREZGENE
OMIM 109195 OMIM
PANTHER PTHR10504 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10504:SF84 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam LBP_BPI_CETP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LBP_BPI_CETP_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA25403 PharmGKB
PIRSF Lipid_binding_protein UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE LBP_BPI_CETP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART BPI1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BPI2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF55394 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0D9SFX6_HUMAN UniProtKB/TrEMBL
  A0A2R8YDF1 ENTREZGENE, UniProtKB/TrEMBL
  B2RCY2 ENTREZGENE
  BPI_HUMAN UniProtKB/Swiss-Prot
  H0Y738 ENTREZGENE, UniProtKB/TrEMBL
  P17213 ENTREZGENE
  Q1ZZU8 ENTREZGENE
  Q5JRW0 ENTREZGENE
  Q8IW58 ENTREZGENE
  Q9BYZ9 ENTREZGENE
  Q9H1L2 ENTREZGENE
  Q9H1M8 ENTREZGENE
  Q9H203 ENTREZGENE
  Q9UCT4 ENTREZGENE
  Q9UD65 ENTREZGENE
UniProt Secondary B2RCY2 UniProtKB/Swiss-Prot
  Q1ZZU8 UniProtKB/Swiss-Prot
  Q5JRW0 UniProtKB/Swiss-Prot
  Q8IW58 UniProtKB/Swiss-Prot
  Q9BYZ9 UniProtKB/Swiss-Prot
  Q9H1L2 UniProtKB/Swiss-Prot
  Q9H1M8 UniProtKB/Swiss-Prot
  Q9H203 UniProtKB/Swiss-Prot
  Q9UCT4 UniProtKB/Swiss-Prot
  Q9UD65 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-02-13 BPI  bactericidal permeability increasing protein  BPI  bactericidal/permeability-increasing protein  Symbol and/or name change 5135510 APPROVED