Gene: CCL11 (C-C motif chemokine ligand 11) Homo sapiens
Symbol: CCL11
Name: C-C motif chemokine ligand 11
Description: This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil-specific chemokine is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. [provided by RefSeq, Sep 2014]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C-C motif chemokine 11; chemokine (C-C motif) ligand 11; eosinophil chemotactic protein; eotaxin; eotaxin-1; MGC22554; OTTHUMP00000163793; SCYA11; small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin); small-inducible cytokine A11
Mus musculus (house mouse) : Ccl11 (chemokine (C-C motif) ligand 11)  MGI  AGR
Rattus norvegicus (Norway rat) : Ccl11 (C-C motif chemokine ligand 11)  AGR
Pan paniscus (bonobo/pygmy chimpanzee) : CCL11 (C-C motif chemokine ligand 11)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ccl11 (C-C motif chemokine ligand 11)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381734,285,668 - 34,288,180 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371732,612,687 - 32,615,199 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361729,636,800 - 29,639,312 (+)NCBINCBI36hg18NCBI36
Build 341729,636,799 - 29,639,312NCBI
Celera1729,522,500 - 29,525,011 (+)NCBI
Cytogenetic Map17q12NCBI
HuRef1728,797,991 - 28,800,502 (+)NCBIHuRef
CHM1_11732,676,549 - 32,679,061 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on CCL11
AGR Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1351854
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2017-11-17
Status: ACTIVE