KRT34 (keratin 34) - Rat Genome Database

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Gene: KRT34 (keratin 34) Homo sapiens
Analyze
Symbol: KRT34
Name: keratin 34
RGD ID: 1350893
HGNC Page HGNC:6452
Description: Predicted to enable structural molecule activity. Predicted to be involved in epithelial cell differentiation and intermediate filament organization. Located in extracellular space.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: Ha-4; HA4; hair keratin, type I Ha4; hard keratin, type I, 4; hHa4; K34; keratin 34, type I; keratin, hair, acidic, 4; keratin, type I cuticular Ha4; keratin-34; KRTHA4
RGD Orthologs
Mouse
Rat
Bonobo
Dog
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381741,377,669 - 41,383,816 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1741,377,669 - 41,382,306 (-)EnsemblGRCh38hg38GRCh38
GRCh371739,533,921 - 39,538,558 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361736,787,447 - 36,792,162 (-)NCBINCBI36Build 36hg18NCBI36
Build 341736,787,446 - 36,792,162NCBI
Celera1736,187,136 - 36,191,851 (-)NCBICelera
Cytogenetic Map17q21.2NCBI
HuRef1735,297,420 - 35,302,136 (-)NCBIHuRef
CHM1_11739,769,265 - 39,773,980 (-)NCBICHM1_1
T2T-CHM13v2.01742,233,202 - 42,239,349 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:2431943   PMID:7686952   PMID:9756910   PMID:10391933   PMID:12477932   PMID:16286979   PMID:16831889   PMID:17353931   PMID:19380743   PMID:19615732   PMID:21873635   PMID:22790218  
PMID:23376485   PMID:23580065   PMID:23686814   PMID:25324306   PMID:26057535   PMID:27591049   PMID:27609421   PMID:28384107   PMID:28508828   PMID:28515276   PMID:31324722   PMID:31835165  
PMID:32296183   PMID:33961781   PMID:35575683   PMID:35864588   PMID:36949045  


Genomics

Comparative Map Data
KRT34
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381741,377,669 - 41,383,816 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1741,377,669 - 41,382,306 (-)EnsemblGRCh38hg38GRCh38
GRCh371739,533,921 - 39,538,558 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361736,787,447 - 36,792,162 (-)NCBINCBI36Build 36hg18NCBI36
Build 341736,787,446 - 36,792,162NCBI
Celera1736,187,136 - 36,191,851 (-)NCBICelera
Cytogenetic Map17q21.2NCBI
HuRef1735,297,420 - 35,302,136 (-)NCBIHuRef
CHM1_11739,769,265 - 39,773,980 (-)NCBICHM1_1
T2T-CHM13v2.01742,233,202 - 42,239,349 (-)NCBIT2T-CHM13v2.0
Krt34
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391199,928,173 - 99,932,380 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1199,928,173 - 99,932,380 (-)EnsemblGRCm39 Ensembl
GRCm3811100,037,347 - 100,041,554 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11100,037,347 - 100,041,554 (-)EnsemblGRCm38mm10GRCm38
MGSCv371199,898,665 - 99,902,868 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361199,853,441 - 99,857,644 (-)NCBIMGSCv36mm8
Celera11110,653,691 - 110,657,895 (-)NCBICelera
Cytogenetic Map11DNCBI
cM Map1163.38NCBI
Krt34
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81085,470,391 - 85,474,501 (-)NCBIGRCr8
mRatBN7.21084,969,988 - 84,974,098 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1084,970,017 - 84,974,040 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1089,988,629 - 89,992,318 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01089,486,772 - 89,490,461 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01084,878,739 - 84,882,429 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01087,950,364 - 87,954,055 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1087,950,001 - 87,954,055 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01087,736,681 - 87,740,372 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41088,973,452 - 88,977,141 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11088,987,821 - 88,991,511 (-)NCBI
Celera1083,690,160 - 83,693,849 (-)NCBICelera
Cytogenetic Map10q31NCBI
LOC100973499
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21923,597,474 - 23,607,210 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11725,487,449 - 25,497,181 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01715,933,144 - 15,939,170 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11716,150,694 - 16,156,671 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1716,151,966 - 16,156,281 (+)Ensemblpanpan1.1panPan2
KRT34
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1921,377,218 - 21,381,019 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl921,377,264 - 21,380,088 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha920,838,959 - 20,842,756 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0922,098,159 - 22,101,956 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl922,098,153 - 22,101,234 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1920,884,135 - 20,887,932 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0921,150,133 - 21,153,930 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0921,253,934 - 21,257,731 (+)NCBIUU_Cfam_GSD_1.0
KRT34
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11221,222,112 - 21,226,971 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21221,391,716 - 21,396,562 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KRT34
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11664,851,026 - 64,855,918 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1664,851,651 - 64,855,510 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607735,696,270 - 35,700,678 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in KRT34
26 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 17q21.33-24.2(chr17:36449220-68170214)x3 copy number gain See cases [RCV000050957] Chr17:36449220..68170214 [GRCh38]
Chr17:48563237..65936105 [GRCh37]
Chr17:45918236..63677950 [NCBI36]
Chr17:17q21.33-24.2		 pathogenic
GRCh38/hg38 17q23.2-25.3(chr17:36449220-83086677)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052483]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052483]|See cases [RCV000052483] Chr17:36449220..83086677 [GRCh38]
Chr17:58617905..81044553 [GRCh37]
Chr17:55972687..78637842 [NCBI36]
Chr17:17q23.2-25.3		 pathogenic
GRCh38/hg38 17q12-21.31(chr17:39199873-45629579)x3 copy number gain See cases [RCV000052479] Chr17:39199873..45629579 [GRCh38]
Chr17:37356126..43706945 [GRCh37]
Chr17:34609652..41062728 [NCBI36]
Chr17:17q12-21.31		 pathogenic
NM_021013.3(KRT34):c.621C>T (p.Ile207=) single nucleotide variant Malignant melanoma [RCV000071467] Chr17:41381149 [GRCh38]
Chr17:39537401 [GRCh37]
Chr17:36790927 [NCBI36]
Chr17:17q21.2		 not provided
GRCh38/hg38 17q23.1-25.1(chr17:36449220-75053130)x3 copy number gain See cases [RCV000137437] Chr17:36449220..75053130 [GRCh38]
Chr17:57595736..73049225 [GRCh37]
Chr17:54950518..70560820 [NCBI36]
Chr17:17q23.1-25.1		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:526-81041938) copy number gain See cases [RCV000511439] Chr17:526..81041938 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
NM_001386014.1(KRT34):c.986G>A (p.Arg329His) single nucleotide variant not specified [RCV004308737] Chr17:41379067 [GRCh38]
Chr17:39535319 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_001386014.1(KRT34):c.1079T>A (p.Leu360Gln) single nucleotide variant not specified [RCV004282401] Chr17:41378974 [GRCh38]
Chr17:39535226 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_001386014.1(KRT34):c.470C>T (p.Ser157Leu) single nucleotide variant not specified [RCV004281557] Chr17:41381174 [GRCh38]
Chr17:39537426 [GRCh37]
Chr17:17q21.2		 uncertain significance
GRCh37/hg19 17p13.3-q25.3(chr17:526-81041938)x3 copy number gain See cases [RCV000512441] Chr17:526..81041938 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:8547-81060040)x3 copy number gain not provided [RCV000739324] Chr17:8547..81060040 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:7214-81058310)x3 copy number gain not provided [RCV000739320] Chr17:7214..81058310 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:12344-81057996)x3 copy number gain not provided [RCV000739325] Chr17:12344..81057996 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
NM_001386014.1(KRT34):c.1042C>T (p.Arg348Trp) single nucleotide variant not specified [RCV004288102] Chr17:41379011 [GRCh38]
Chr17:39535263 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_001386014.1(KRT34):c.1064C>T (p.Thr355Met) single nucleotide variant not specified [RCV004289635] Chr17:41378989 [GRCh38]
Chr17:39535241 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_001386014.1(KRT34):c.157A>G (p.Asn53Asp) single nucleotide variant not specified [RCV004143208] Chr17:41382090 [GRCh38]
Chr17:39538342 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_001386014.1(KRT34):c.-59A>C single nucleotide variant not specified [RCV004107945] Chr17:41382305 [GRCh38]
Chr17:39538557 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_001386014.1(KRT34):c.367G>C (p.Glu123Gln) single nucleotide variant not specified [RCV004201712] Chr17:41381777 [GRCh38]
Chr17:39538029 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_001386014.1(KRT34):c.985C>T (p.Arg329Cys) single nucleotide variant not specified [RCV004198803] Chr17:41379068 [GRCh38]
Chr17:39535320 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_001386014.1(KRT34):c.488G>A (p.Arg163His) single nucleotide variant not specified [RCV004244006] Chr17:41381156 [GRCh38]
Chr17:39537408 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_001386014.1(KRT34):c.910G>A (p.Glu304Lys) single nucleotide variant not specified [RCV004199677] Chr17:41379143 [GRCh38]
Chr17:39535395 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_001386014.1(KRT34):c.947G>A (p.Ser316Asn) single nucleotide variant not specified [RCV004088187] Chr17:41379106 [GRCh38]
Chr17:39535358 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_001386014.1(KRT34):c.977C>T (p.Ala326Val) single nucleotide variant not specified [RCV004116944] Chr17:41379076 [GRCh38]
Chr17:39535328 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_001386014.1(KRT34):c.945G>C (p.Gln315His) single nucleotide variant not specified [RCV004102761] Chr17:41379108 [GRCh38]
Chr17:39535360 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_001386014.1(KRT34):c.1133G>C (p.Ser378Thr) single nucleotide variant not specified [RCV004196506] Chr17:41378111 [GRCh38]
Chr17:39534363 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_001386014.1(KRT34):c.271C>T (p.Arg91Trp) single nucleotide variant not specified [RCV004080142] Chr17:41381976 [GRCh38]
Chr17:39538228 [GRCh37]
Chr17:17q21.2		 likely benign
NM_001386014.1(KRT34):c.538G>A (p.Val180Met) single nucleotide variant not specified [RCV004098982] Chr17:41381106 [GRCh38]
Chr17:39537358 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_001386014.1(KRT34):c.631G>C (p.Val211Leu) single nucleotide variant not specified [RCV004217402] Chr17:41379689 [GRCh38]
Chr17:39535941 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_001386014.1(KRT34):c.-18A>G single nucleotide variant not specified [RCV004283358] Chr17:41382264 [GRCh38]
Chr17:39538516 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_001386014.1(KRT34):c.487C>T (p.Arg163Cys) single nucleotide variant not specified [RCV004286262] Chr17:41381157 [GRCh38]
Chr17:39537409 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_001386014.1(KRT34):c.757G>C (p.Glu253Gln) single nucleotide variant not specified [RCV004339119] Chr17:41379472 [GRCh38]
Chr17:39535724 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_001386014.1(KRT34):c.728T>G (p.Val243Gly) single nucleotide variant not specified [RCV004361193] Chr17:41379592 [GRCh38]
Chr17:39535844 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_001386014.1(KRT34):c.1116C>G (p.Cys372Trp) single nucleotide variant not specified [RCV004342628] Chr17:41378128 [GRCh38]
Chr17:39534380 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_001386014.1(KRT34):c.758A>T (p.Glu253Val) single nucleotide variant not specified [RCV004339121] Chr17:41379471 [GRCh38]
Chr17:39535723 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_001386014.1(KRT34):c.1116C>T (p.Cys372=) single nucleotide variant not provided [RCV003413227] Chr17:41378128 [GRCh38]
Chr17:39534380 [GRCh37]
Chr17:17q21.2		 likely benign
NM_001386014.1(KRT34):c.1037G>C (p.Arg346Pro) single nucleotide variant not specified [RCV004412335] Chr17:41379016 [GRCh38]
Chr17:39535268 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_001386014.1(KRT34):c.26G>A (p.Ser9Asn) single nucleotide variant not specified [RCV004412336] Chr17:41382221 [GRCh38]
Chr17:39538473 [GRCh37]
Chr17:17q21.2		 likely benign
NM_001386014.1(KRT34):c.53C>T (p.Ser18Phe) single nucleotide variant not specified [RCV004412337] Chr17:41382194 [GRCh38]
Chr17:39538446 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_001386014.1(KRT34):c.371A>G (p.Asn124Ser) single nucleotide variant not specified [RCV004412339] Chr17:41381773 [GRCh38]
Chr17:39538025 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_001386014.1(KRT34):c.577A>C (p.Asn193His) single nucleotide variant not specified [RCV004412340] Chr17:41381067 [GRCh38]
Chr17:39537319 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_001386014.1(KRT34):c.607T>C (p.Ser203Pro) single nucleotide variant not specified [RCV004412341] Chr17:41379713 [GRCh38]
Chr17:39535965 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_001386014.1(KRT34):c.392T>C (p.Ile131Thr) single nucleotide variant not specified [RCV004644501] Chr17:41381752 [GRCh38]
Chr17:39538004 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_001386014.1(KRT34):c.499G>A (p.Asp167Asn) single nucleotide variant not specified [RCV004644499] Chr17:41381145 [GRCh38]
Chr17:39537397 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_001386014.1(KRT34):c.44G>C (p.Ser15Thr) single nucleotide variant not specified [RCV004644500] Chr17:41382203 [GRCh38]
Chr17:39538455 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_001386014.1(KRT34):c.1070G>A (p.Arg357Gln) single nucleotide variant not specified [RCV004644502] Chr17:41378983 [GRCh38]
Chr17:39535235 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_001386014.1(KRT34):c.1142C>A (p.Ser381Tyr) single nucleotide variant not specified [RCV004644503] Chr17:41378102 [GRCh38]
Chr17:39534354 [GRCh37]
Chr17:17q21.2		 uncertain significance
NM_001386014.1(KRT34):c.325A>C (p.Thr109Pro) single nucleotide variant not specified [RCV004644504] Chr17:41381922 [GRCh38]
Chr17:39538174 [GRCh37]
Chr17:17q21.2		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:146
Count of miRNA genes:136
Interacting mature miRNAs:137
Transcripts:ENST00000394001
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
RH99021  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371739,534,216 - 39,534,368UniSTSGRCh37
Build 361736,787,742 - 36,787,894RGDNCBI36
Celera1736,187,431 - 36,187,583RGD
Cytogenetic Map17q21.2UniSTS
HuRef1735,297,715 - 35,297,867UniSTS
GeneMap99-GB4 RH Map17307.04UniSTS
SHGC-57298  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371739,533,961 - 39,534,101UniSTSGRCh37
Build 361736,787,487 - 36,787,627RGDNCBI36
Celera1736,187,176 - 36,187,316RGD
Cytogenetic Map17q21.2UniSTS
HuRef1735,297,460 - 35,297,600UniSTS
TNG Radiation Hybrid Map1718471.0UniSTS
KRTHA4__6359  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371739,533,779 - 39,534,320UniSTSGRCh37
Build 361736,787,305 - 36,787,846RGDNCBI36
Celera1736,186,994 - 36,187,535RGD
HuRef1735,297,278 - 35,297,819UniSTS


Sequence


Ensembl Acc Id: ENST00000394001   ⟹   ENSP00000377570
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1741,377,650 - 41,382,403 (-)Ensembl
RefSeq Acc Id: NM_001386014   ⟹   NP_001372943
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381741,377,669 - 41,382,306 (-)NCBI
T2T-CHM13v2.01742,233,202 - 42,237,839 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011524793   ⟹   XP_011523095
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381741,377,669 - 41,383,816 (-)NCBI
Sequence:
RefSeq Acc Id: XM_054316040   ⟹   XP_054172015
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01742,233,202 - 42,239,349 (-)NCBI
RefSeq Acc Id: XP_011523095   ⟸   XM_011524793
- Peptide Label: isoform X1
- UniProtKB: A0A140TA69 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSP00000377570   ⟸   ENST00000394001
RefSeq Acc Id: NP_001372943   ⟸   NM_001386014
- UniProtKB: Q8N4W2 (UniProtKB/Swiss-Prot),   Q8IUT8 (UniProtKB/Swiss-Prot),   O76011 (UniProtKB/Swiss-Prot),   A0A140TA69 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054172015   ⟸   XM_054316040
- Peptide Label: isoform X1
- UniProtKB: A0A140TA69 (UniProtKB/TrEMBL)
Protein Domains
IF rod

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O76011-F1-model_v2 AlphaFold O76011 1-436 view protein structure

Promoters
RGD ID:7234977
Promoter ID:EPDNEW_H23232
Type:multiple initiation site
Name:KRT34_1
Description:keratin 34
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H23233  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381741,382,306 - 41,382,366EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:6452 AgrOrtholog
COSMIC KRT34 COSMIC
Ensembl Genes ENSG00000131737 Ensembl, ENTREZGENE
  ENSG00000262045 UniProtKB/TrEMBL
Ensembl Transcript ENST00000394001 ENTREZGENE
  ENST00000571312.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.170 UniProtKB/TrEMBL
  Single helix bin UniProtKB/TrEMBL
  Vasodilator-stimulated phosphoprotein UniProtKB/TrEMBL
GTEx ENSG00000131737 GTEx
  ENSG00000262045 GTEx
HGNC ID HGNC:6452 ENTREZGENE
Human Proteome Map KRT34 Human Proteome Map
InterPro IF_conserved UniProtKB/TrEMBL
  IF_rod_dom UniProtKB/TrEMBL
  Keratin_I UniProtKB/TrEMBL
NCBI Gene 3885 ENTREZGENE
OMIM 602763 OMIM
PANTHER IF ROD DOMAIN-CONTAINING PROTEIN-RELATED UniProtKB/TrEMBL
  PTHR23239 UniProtKB/TrEMBL
Pfam Filament UniProtKB/TrEMBL
PharmGKB PA30241 PharmGKB
PRINTS TYPE1KERATIN UniProtKB/TrEMBL
PROSITE IF_ROD_1 UniProtKB/TrEMBL
  IF_ROD_2 UniProtKB/TrEMBL
SMART Filament UniProtKB/TrEMBL
Superfamily-SCOP Intermediate filament protein, coiled coil region UniProtKB/TrEMBL
UniProt A0A140TA69 ENTREZGENE, UniProtKB/TrEMBL
  L0R6J1_HUMAN UniProtKB/TrEMBL
  O76011 ENTREZGENE
  Q8IUT8 ENTREZGENE
  Q8N4W2 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-14 KRT34  keratin 34  KRT34  keratin 34, type I  Symbol and/or name change 5135510 APPROVED
2015-01-27 KRT34  keratin 34, type I  KRT34  keratin 34  Symbol and/or name change 5135510 APPROVED