OVGP1 (oviductal glycoprotein 1) - Rat Genome Database

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Gene: OVGP1 (oviductal glycoprotein 1) Homo sapiens
Analyze
Symbol: OVGP1
Name: oviductal glycoprotein 1
RGD ID: 1349339
HGNC Page HGNC:8524
Description: Predicted to enable chitin binding activity and chitinase activity. Predicted to be involved in chitin catabolic process. Predicted to act upstream of or within negative regulation of binding activity of sperm to zona pellucida. Located in intracellular membrane-bounded organelle and microtubule cytoskeleton.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: CHIT5; EGP; estrogen-dependent oviduct protein; MUC9; mucin 9; mucin-9; OGP; oviduct glycoprotein; oviduct-specific glycoprotein; oviductal glycoprotein 1, 120kDa; oviductin
RGD Orthologs
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381111,414,319 - 111,427,735 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1111,414,319 - 111,427,735 (-)EnsemblGRCh38hg38GRCh38
GRCh371111,956,941 - 111,970,357 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361111,758,460 - 111,771,922 (-)NCBINCBI36Build 36hg18NCBI36
Build 341111,668,979 - 111,682,441NCBI
Celera1110,203,892 - 110,217,354 (-)NCBICelera
Cytogenetic Map1p13.2NCBI
HuRef1109,828,378 - 109,841,840 (-)NCBIHuRef
CHM1_11112,071,958 - 112,085,420 (-)NCBICHM1_1
T2T-CHM13v2.01111,429,011 - 111,442,427 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:3278893   PMID:7819450   PMID:9109822   PMID:9341614   PMID:10728974   PMID:11818519   PMID:12477932   PMID:12503889   PMID:14641477   PMID:15489334   PMID:15585630   PMID:16169070  
PMID:16209999   PMID:16567366   PMID:16710414   PMID:18834073   PMID:20130498   PMID:20800603   PMID:21873635   PMID:21988832   PMID:22028245   PMID:29968069   PMID:31254143   PMID:32393512  
PMID:33961781   PMID:34857952   PMID:36724073  


Genomics

Comparative Map Data
OVGP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381111,414,319 - 111,427,735 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1111,414,319 - 111,427,735 (-)EnsemblGRCh38hg38GRCh38
GRCh371111,956,941 - 111,970,357 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361111,758,460 - 111,771,922 (-)NCBINCBI36Build 36hg18NCBI36
Build 341111,668,979 - 111,682,441NCBI
Celera1110,203,892 - 110,217,354 (-)NCBICelera
Cytogenetic Map1p13.2NCBI
HuRef1109,828,378 - 109,841,840 (-)NCBIHuRef
CHM1_11112,071,958 - 112,085,420 (-)NCBICHM1_1
T2T-CHM13v2.01111,429,011 - 111,442,427 (-)NCBIT2T-CHM13v2.0
Ovgp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393105,881,118 - 105,894,739 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3105,881,027 - 105,894,739 (+)EnsemblGRCm39 Ensembl
GRCm383105,973,802 - 105,987,423 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3105,973,711 - 105,987,423 (+)EnsemblGRCm38mm10GRCm38
MGSCv373105,776,720 - 105,790,341 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363106,101,858 - 106,115,479 (+)NCBIMGSCv36mm8
Celera3108,164,222 - 108,177,644 (+)NCBICelera
Cytogenetic Map3F2.2NCBI
cM Map346.46NCBI
Ovgp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543514,915,537 - 14,928,679 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543514,915,168 - 14,929,171 (-)NCBIChiLan1.0ChiLan1.0
OVGP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21115,588,749 - 115,613,483 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11114,745,767 - 114,763,308 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01114,075,675 - 114,094,893 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11126,256,994 - 126,271,353 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1126,257,983 - 126,271,204 (+)Ensemblpanpan1.1panPan2
OVGP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11763,955,766 - 63,985,878 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1763,957,251 - 63,983,421 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1763,487,521 - 63,499,130 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01765,127,426 - 65,156,345 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1765,128,910 - 65,155,412 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11763,861,995 - 63,891,566 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01763,921,188 - 63,950,657 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01764,719,349 - 64,748,293 (+)NCBIUU_Cfam_GSD_1.0
Ovgp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505817,369,341 - 17,381,951 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493669096,091 - 105,613 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493669095,985 - 108,390 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OVGP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4108,929,357 - 108,941,038 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14108,929,034 - 108,941,040 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24119,103,779 - 119,124,275 (+)NCBISscrofa10.2Sscrofa10.2susScr3
OVGP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12022,183,429 - 22,197,636 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2022,184,849 - 22,197,684 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603836,281,610 - 36,294,471 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in OVGP1
56 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 1p13.3-12(chr1:109756630-118650204)x3 copy number gain See cases [RCV000051827] Chr1:109756630..118650204 [GRCh38]
Chr1:110299252..119192827 [GRCh37]
Chr1:110100775..118994350 [NCBI36]
Chr1:1p13.3-12
pathogenic
GRCh38/hg38 1p21.2-13.2(chr1:101618097-111703028)x1 copy number loss See cases [RCV000053879] Chr1:101618097..111703028 [GRCh38]
Chr1:102083653..112245650 [GRCh37]
Chr1:101856241..112047173 [NCBI36]
Chr1:1p21.2-13.2
pathogenic
NM_002557.3(OVGP1):c.378C>T (p.Ser126=) single nucleotide variant Malignant melanoma [RCV000064018] Chr1:111423648 [GRCh38]
Chr1:111966270 [GRCh37]
Chr1:111767793 [NCBI36]
Chr1:1p13.2
not provided
GRCh38/hg38 1p21.1-12(chr1:104325484-119977655)x3 copy number gain See cases [RCV000142953] Chr1:104325484..119977655 [GRCh38]
Chr1:104868106..120471049 [GRCh37]
Chr1:104669629..120321801 [NCBI36]
Chr1:1p21.1-12
pathogenic
GRCh38/hg38 1p21.1-13.2(chr1:105468292-112190626)x1 copy number loss See cases [RCV000142760] Chr1:105468292..112190626 [GRCh38]
Chr1:106010914..112733248 [GRCh37]
Chr1:105812437..112534771 [NCBI36]
Chr1:1p21.1-13.2
pathogenic
GRCh37/hg19 1p36.12-12(chr1:20608823-120546301)x3 copy number loss not provided [RCV000762767] Chr1:20608823..120546301 [GRCh37]
Chr1:1p36.12-12
likely benign
NM_002557.4(OVGP1):c.1599_1600insACTGGACAGAAGACCCTGACC (p.Thr533_Pro534insThrGlyGlnLysThrLeuThr) insertion not specified [RCV000239349] Chr1:111414901..111414902 [GRCh38]
Chr1:111957523..111957524 [GRCh37]
Chr1:1p13.2
benign
GRCh37/hg19 1p36.33-q44(chr1:849467-249224684)x3 copy number gain See cases [RCV000510383] Chr1:849467..249224684 [GRCh37]
Chr1:1p36.33-q44
pathogenic
GRCh37/hg19 1p36.33-q44(chr1:849467-249224684) copy number gain See cases [RCV000510926] Chr1:849467..249224684 [GRCh37]
Chr1:1p36.33-q44
pathogenic
NM_002557.4(OVGP1):c.377C>A (p.Ser126Tyr) single nucleotide variant not specified [RCV004323545] Chr1:111423649 [GRCh38]
Chr1:111966271 [GRCh37]
Chr1:1p13.2
uncertain significance
NM_002557.4(OVGP1):c.1711C>T (p.Arg571Cys) single nucleotide variant not specified [RCV004332086] Chr1:111414790 [GRCh38]
Chr1:111957412 [GRCh37]
Chr1:1p13.2
uncertain significance
NM_002557.4(OVGP1):c.116C>T (p.Ala39Val) single nucleotide variant not specified [RCV004319559] Chr1:111426581 [GRCh38]
Chr1:111969203 [GRCh37]
Chr1:1p13.2
uncertain significance
GRCh37/hg19 1p22.1-11.2(chr1:93837992-121343783)x3 copy number gain See cases [RCV000512354] Chr1:93837992..121343783 [GRCh37]
Chr1:1p22.1-11.2
pathogenic
GRCh37/hg19 1p36.33-q44(chr1:47851-249228449)x3 copy number gain not provided [RCV000736295] Chr1:47851..249228449 [GRCh37]
Chr1:1p36.33-q44
pathogenic
GRCh37/hg19 1p36.33-q44(chr1:82154-249218992)x3 copy number gain not provided [RCV000736305] Chr1:82154..249218992 [GRCh37]
Chr1:1p36.33-q44
pathogenic
NM_002557.4(OVGP1):c.215A>G (p.Gln72Arg) single nucleotide variant not specified [RCV004296484] Chr1:111426482 [GRCh38]
Chr1:111969104 [GRCh37]
Chr1:1p13.2
uncertain significance
NM_002557.4(OVGP1):c.1402G>A (p.Gly468Arg) single nucleotide variant not provided [RCV000965557] Chr1:111415099 [GRCh38]
Chr1:111957721 [GRCh37]
Chr1:1p13.2
benign
NM_002557.4(OVGP1):c.541C>T (p.Leu181=) single nucleotide variant not provided [RCV000901065] Chr1:111422994 [GRCh38]
Chr1:111965616 [GRCh37]
Chr1:1p13.2
benign
NM_002557.4(OVGP1):c.1531_1575del (p.Ser511_Thr525del) deletion not provided [RCV000946482] Chr1:111414926..111414970 [GRCh38]
Chr1:111957548..111957592 [GRCh37]
Chr1:1p13.2
benign
NM_002557.4(OVGP1):c.1244C>T (p.Thr415Met) single nucleotide variant not provided [RCV000923527] Chr1:111415257 [GRCh38]
Chr1:111957879 [GRCh37]
Chr1:1p13.2
likely benign
NM_002557.4(OVGP1):c.1598_1621del (p.Thr533_Val540del) deletion not provided [RCV000946481] Chr1:111414880..111414903 [GRCh38]
Chr1:111957502..111957525 [GRCh37]
Chr1:1p13.2
benign
NM_002557.4(OVGP1):c.1606A>G (p.Ser536Gly) single nucleotide variant not provided [RCV000972063] Chr1:111414895 [GRCh38]
Chr1:111957517 [GRCh37]
Chr1:1p13.2
benign
GRCh37/hg19 1p13.3-13.2(chr1:110994179-112360446)x1 copy number loss not provided [RCV000849607] Chr1:110994179..112360446 [GRCh37]
Chr1:1p13.3-13.2
pathogenic
NM_002557.4(OVGP1):c.881A>G (p.Glu294Gly) single nucleotide variant not specified [RCV004321306] Chr1:111421298 [GRCh38]
Chr1:111963920 [GRCh37]
Chr1:1p13.2
uncertain significance
NM_002557.4(OVGP1):c.1598C>G (p.Thr533Ser) single nucleotide variant not provided [RCV000888619] Chr1:111414903 [GRCh38]
Chr1:111957525 [GRCh37]
Chr1:1p13.2
benign
NM_002557.4(OVGP1):c.1753C>G (p.Pro585Ala) single nucleotide variant not provided [RCV000955746] Chr1:111414748 [GRCh38]
Chr1:111957370 [GRCh37]
Chr1:1p13.2
benign
GRCh37/hg19 1p21.2-12(chr1:102021465-119737478) copy number loss Seizure [RCV001352640] Chr1:102021465..119737478 [GRCh37]
Chr1:1p21.2-12
pathogenic
GRCh37/hg19 1p13.3-11.2(chr1:111647582-121343783) copy number gain not specified [RCV002053602] Chr1:111647582..121343783 [GRCh37]
Chr1:1p13.3-11.2
pathogenic
GRCh37/hg19 1p21.3-13.2(chr1:95046805-114714931) copy number loss not specified [RCV002053503] Chr1:95046805..114714931 [GRCh37]
Chr1:1p21.3-13.2
pathogenic
NC_000001.10:g.(?_111145905)_(114454813_?)del deletion not provided [RCV003113195] Chr1:111145905..114454813 [GRCh37]
Chr1:1p13.3-13.2
pathogenic
NM_002557.4(OVGP1):c.115G>T (p.Ala39Ser) single nucleotide variant not specified [RCV004319558] Chr1:111426582 [GRCh38]
Chr1:111969204 [GRCh37]
Chr1:1p13.2
uncertain significance
NM_002557.4(OVGP1):c.425A>G (p.Tyr142Cys) single nucleotide variant not specified [RCV004099159] Chr1:111423601 [GRCh38]
Chr1:111966223 [GRCh37]
Chr1:1p13.2
uncertain significance
NM_002557.4(OVGP1):c.329T>C (p.Met110Thr) single nucleotide variant not specified [RCV004097982] Chr1:111423697 [GRCh38]
Chr1:111966319 [GRCh37]
Chr1:1p13.2
uncertain significance
NM_002557.4(OVGP1):c.89A>G (p.Asn30Ser) single nucleotide variant not specified [RCV004164225] Chr1:111426608 [GRCh38]
Chr1:111969230 [GRCh37]
Chr1:1p13.2
uncertain significance
NM_002557.4(OVGP1):c.374T>C (p.Ile125Thr) single nucleotide variant not specified [RCV004195184] Chr1:111423652 [GRCh38]
Chr1:111966274 [GRCh37]
Chr1:1p13.2
uncertain significance
NM_002557.4(OVGP1):c.1760G>A (p.Gly587Glu) single nucleotide variant not specified [RCV004139611] Chr1:111414741 [GRCh38]
Chr1:111957363 [GRCh37]
Chr1:1p13.2
uncertain significance
NM_002557.4(OVGP1):c.292G>A (p.Gly98Ser) single nucleotide variant not specified [RCV004214705] Chr1:111425408 [GRCh38]
Chr1:111968030 [GRCh37]
Chr1:1p13.2
uncertain significance
NM_002557.4(OVGP1):c.1378C>T (p.Leu460Phe) single nucleotide variant not specified [RCV004170220] Chr1:111415123 [GRCh38]
Chr1:111957745 [GRCh37]
Chr1:1p13.2
likely benign
NM_002557.4(OVGP1):c.1448G>A (p.Gly483Asp) single nucleotide variant not specified [RCV004163211] Chr1:111415053 [GRCh38]
Chr1:111957675 [GRCh37]
Chr1:1p13.2
uncertain significance
NM_002557.4(OVGP1):c.458G>A (p.Arg153Gln) single nucleotide variant not specified [RCV004140175] Chr1:111423568 [GRCh38]
Chr1:111966190 [GRCh37]
Chr1:1p13.2
uncertain significance
NM_002557.4(OVGP1):c.1526T>C (p.Leu509Pro) single nucleotide variant not specified [RCV004083799] Chr1:111414975 [GRCh38]
Chr1:111957597 [GRCh37]
Chr1:1p13.2
uncertain significance
NM_002557.4(OVGP1):c.802C>T (p.Arg268Cys) single nucleotide variant not specified [RCV004074725] Chr1:111421377 [GRCh38]
Chr1:111963999 [GRCh37]
Chr1:1p13.2
uncertain significance
NM_002557.4(OVGP1):c.1858A>T (p.Met620Leu) single nucleotide variant not specified [RCV004210006] Chr1:111414643 [GRCh38]
Chr1:111957265 [GRCh37]
Chr1:1p13.2
uncertain significance
NM_002557.4(OVGP1):c.1220A>G (p.Asp407Gly) single nucleotide variant not specified [RCV004095283] Chr1:111415281 [GRCh38]
Chr1:111957903 [GRCh37]
Chr1:1p13.2
likely benign
NM_002557.4(OVGP1):c.1999G>A (p.Glu667Lys) single nucleotide variant not specified [RCV004101199] Chr1:111414502 [GRCh38]
Chr1:111957124 [GRCh37]
Chr1:1p13.2
uncertain significance
NM_002557.4(OVGP1):c.1945C>T (p.His649Tyr) single nucleotide variant not specified [RCV004116054] Chr1:111414556 [GRCh38]
Chr1:111957178 [GRCh37]
Chr1:1p13.2
uncertain significance
NM_002557.4(OVGP1):c.1037G>A (p.Arg346Gln) single nucleotide variant not specified [RCV004084264] Chr1:111416442 [GRCh38]
Chr1:111959064 [GRCh37]
Chr1:1p13.2
uncertain significance
NM_002557.4(OVGP1):c.224A>G (p.Lys75Arg) single nucleotide variant not specified [RCV004080453] Chr1:111426473 [GRCh38]
Chr1:111969095 [GRCh37]
Chr1:1p13.2
uncertain significance
NM_002557.4(OVGP1):c.1951T>G (p.Ser651Ala) single nucleotide variant not specified [RCV004226289] Chr1:111414550 [GRCh38]
Chr1:111957172 [GRCh37]
Chr1:1p13.2
uncertain significance
NM_002557.4(OVGP1):c.1208C>G (p.Ser403Cys) single nucleotide variant not specified [RCV004292174] Chr1:111415293 [GRCh38]
Chr1:111957915 [GRCh37]
Chr1:1p13.2
uncertain significance
NM_002557.4(OVGP1):c.112C>T (p.Pro38Ser) single nucleotide variant not specified [RCV004280001] Chr1:111426585 [GRCh38]
Chr1:111969207 [GRCh37]
Chr1:1p13.2
uncertain significance
NM_002557.4(OVGP1):c.1444G>A (p.Val482Met) single nucleotide variant not specified [RCV004273629] Chr1:111415057 [GRCh38]
Chr1:111957679 [GRCh37]
Chr1:1p13.2
uncertain significance
NM_002557.4(OVGP1):c.1309G>A (p.Gly437Arg) single nucleotide variant not specified [RCV004251027] Chr1:111415192 [GRCh38]
Chr1:111957814 [GRCh37]
Chr1:1p13.2
likely benign
NM_002557.4(OVGP1):c.1785G>C (p.Glu595Asp) single nucleotide variant not specified [RCV004319497] Chr1:111414716 [GRCh38]
Chr1:111957338 [GRCh37]
Chr1:1p13.2
uncertain significance
NM_002557.4(OVGP1):c.53A>T (p.Asp18Val) single nucleotide variant not specified [RCV004363158] Chr1:111427064 [GRCh38]
Chr1:111969686 [GRCh37]
Chr1:1p13.2
uncertain significance
NM_002557.4(OVGP1):c.1049G>T (p.Gly350Val) single nucleotide variant not specified [RCV004335192] Chr1:111416430 [GRCh38]
Chr1:111959052 [GRCh37]
Chr1:1p13.2
uncertain significance
GRCh37/hg19 1p13.3-13.1(chr1:110066946-116672408)x1 copy number loss not provided [RCV003483294] Chr1:110066946..116672408 [GRCh37]
Chr1:1p13.3-13.1
pathogenic
GRCh37/hg19 1p13.3-13.2(chr1:109483388-112293512)x1 copy number loss not provided [RCV003483272] Chr1:109483388..112293512 [GRCh37]
Chr1:1p13.3-13.2
pathogenic
GRCh37/hg19 1p13.3-13.2(chr1:109700156-112176616)x1 copy number loss not specified [RCV003987183] Chr1:109700156..112176616 [GRCh37]
Chr1:1p13.3-13.2
uncertain significance
NM_002557.4(OVGP1):c.1294G>C (p.Val432Leu) single nucleotide variant not specified [RCV004504853] Chr1:111415207 [GRCh38]
Chr1:111957829 [GRCh37]
Chr1:1p13.2
uncertain significance
NM_002557.4(OVGP1):c.595C>T (p.Arg199Cys) single nucleotide variant not specified [RCV004504861] Chr1:111422940 [GRCh38]
Chr1:111965562 [GRCh37]
Chr1:1p13.2
uncertain significance
NM_002557.4(OVGP1):c.1783G>C (p.Glu595Gln) single nucleotide variant not specified [RCV004504856] Chr1:111414718 [GRCh38]
Chr1:111957340 [GRCh37]
Chr1:1p13.2
uncertain significance
NM_002557.4(OVGP1):c.526C>T (p.Arg176Cys) single nucleotide variant not specified [RCV004504860] Chr1:111423009 [GRCh38]
Chr1:111965631 [GRCh37]
Chr1:1p13.2
uncertain significance
NM_002557.4(OVGP1):c.978A>C (p.Lys326Asn) single nucleotide variant not specified [RCV004504863] Chr1:111419652 [GRCh38]
Chr1:111962274 [GRCh37]
Chr1:1p13.2
uncertain significance
NM_002557.4(OVGP1):c.1394T>C (p.Val465Ala) single nucleotide variant not specified [RCV004504854] Chr1:111415107 [GRCh38]
Chr1:111957729 [GRCh37]
Chr1:1p13.2
uncertain significance
NM_002557.4(OVGP1):c.1552A>G (p.Thr518Ala) single nucleotide variant not specified [RCV004504855] Chr1:111414949 [GRCh38]
Chr1:111957571 [GRCh37]
Chr1:1p13.2
uncertain significance
NM_002557.4(OVGP1):c.1282G>A (p.Gly428Arg) single nucleotide variant not specified [RCV004504852] Chr1:111415219 [GRCh38]
Chr1:111957841 [GRCh37]
Chr1:1p13.2
uncertain significance
NM_002557.4(OVGP1):c.349C>T (p.Arg117Cys) single nucleotide variant not specified [RCV004504859] Chr1:111423677 [GRCh38]
Chr1:111966299 [GRCh37]
Chr1:1p13.2
uncertain significance
NM_002557.4(OVGP1):c.1958A>G (p.Asn653Ser) single nucleotide variant not specified [RCV004504857] Chr1:111414543 [GRCh38]
Chr1:111957165 [GRCh37]
Chr1:1p13.2
uncertain significance
NM_002557.4(OVGP1):c.251T>A (p.Leu84Gln) single nucleotide variant not specified [RCV004504858] Chr1:111426446 [GRCh38]
Chr1:111969068 [GRCh37]
Chr1:1p13.2
uncertain significance
NM_002557.4(OVGP1):c.70C>T (p.Leu24Phe) single nucleotide variant not specified [RCV004504862] Chr1:111426627 [GRCh38]
Chr1:111969249 [GRCh37]
Chr1:1p13.2
uncertain significance
NM_002557.4(OVGP1):c.1185T>G (p.Phe395Leu) single nucleotide variant not specified [RCV004661946] Chr1:111415316 [GRCh38]
Chr1:111957938 [GRCh37]
Chr1:1p13.2
uncertain significance
NM_002557.4(OVGP1):c.130C>T (p.His44Tyr) single nucleotide variant not specified [RCV004650595] Chr1:111426567 [GRCh38]
Chr1:111969189 [GRCh37]
Chr1:1p13.2
uncertain significance
NM_002557.4(OVGP1):c.1639A>G (p.Met547Val) single nucleotide variant not specified [RCV004650593] Chr1:111414862 [GRCh38]
Chr1:111957484 [GRCh37]
Chr1:1p13.2
uncertain significance
NM_002557.4(OVGP1):c.1285G>C (p.Glu429Gln) single nucleotide variant not specified [RCV004650594] Chr1:111415216 [GRCh38]
Chr1:111957838 [GRCh37]
Chr1:1p13.2
uncertain significance
NM_002557.4(OVGP1):c.56G>A (p.Gly19Asp) single nucleotide variant not specified [RCV004661945] Chr1:111426641 [GRCh38]
Chr1:111969263 [GRCh37]
Chr1:1p13.2
uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:683
Count of miRNA genes:461
Interacting mature miRNAs:518
Transcripts:ENST00000369732, ENST00000481495, ENST00000494622, ENST00000540696
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300021BP45_HBlood pressure QTL 45 (human)1.770.00218Blood pressuresystolic1103389009129389009Human
597066426GWAS1162500_Ht-tau:beta-amyloid 1-42 ratio measurement QTL GWAS1162500 (human)3e-08cerebral cortex integrity trait (VT:0010923)1111419634111419635Human

Markers in Region
D1S3210  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371111,956,983 - 111,957,096UniSTSGRCh37
Build 361111,758,506 - 111,758,619RGDNCBI36
Celera1110,203,938 - 110,204,051RGD
Cytogenetic Map1p13UniSTS
HuRef1109,828,424 - 109,828,537UniSTS
TNG Radiation Hybrid Map160304.0UniSTS
Stanford-G3 RH Map15205.0UniSTS
GeneMap99-GB4 RH Map1356.47UniSTS
NCBI RH Map1815.2UniSTS
GeneMap99-G3 RH Map15161.0UniSTS
RH70550  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371111,957,077 - 111,957,303UniSTSGRCh37
Build 361111,758,600 - 111,758,826RGDNCBI36
Celera1110,204,032 - 110,204,258RGD
Cytogenetic Map1p13UniSTS
HuRef1109,828,518 - 109,828,744UniSTS
GeneMap99-GB4 RH Map1355.37UniSTS
OVGP1_1686  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371111,956,939 - 111,957,794UniSTSGRCh37
Build 361111,758,462 - 111,759,317RGDNCBI36
Celera1110,203,894 - 110,204,749RGD
HuRef1109,828,380 - 109,829,235UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
1204 2432 2788 2245 4943 1723 2349 5 622 1945 465 2267 7286 6457 52 3710 852 1739 1614 171

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_052675 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_002557 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA909093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB208783 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF189710 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH003613 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK295207 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK298757 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK301726 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK314074 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL390195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY189737 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC126177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC136406 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471122 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U09550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENST00000369732   ⟹   ENSP00000358747
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1111,414,319 - 111,427,735 (-)Ensembl
Ensembl Acc Id: ENST00000481495
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1111,419,610 - 111,423,051 (-)Ensembl
Ensembl Acc Id: ENST00000494622
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1111,415,220 - 111,416,679 (-)Ensembl
RefSeq Acc Id: NM_002557   ⟹   NP_002548
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381111,414,319 - 111,427,735 (-)NCBI
GRCh371111,956,937 - 111,970,399 (-)ENTREZGENE
Build 361111,758,460 - 111,771,922 (-)NCBI Archive
HuRef1109,828,378 - 109,841,840 (-)ENTREZGENE
CHM1_11112,071,958 - 112,085,420 (-)NCBI
T2T-CHM13v2.01111,429,011 - 111,442,427 (-)NCBI
Sequence:
RefSeq Acc Id: NP_002548   ⟸   NM_002557
- Peptide Label: precursor
- UniProtKB: Q12889 (UniProtKB/Swiss-Prot),   B9EGE1 (UniProtKB/Swiss-Prot),   A0AV19 (UniProtKB/Swiss-Prot),   Q15841 (UniProtKB/Swiss-Prot),   Q86YN0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSP00000358747   ⟸   ENST00000369732
Protein Domains
GH18

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q12889-F1-model_v2 AlphaFold Q12889 1-678 view protein structure

Promoters
RGD ID:6856592
Promoter ID:EPDNEW_H1461
Type:multiple initiation site
Name:OVGP1_1
Description:oviductal glycoprotein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H1462  EPDNEW_H1463  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381111,427,735 - 111,427,795EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:8524 AgrOrtholog
COSMIC OVGP1 COSMIC
Ensembl Genes ENSG00000085465 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000369732 ENTREZGENE
  ENST00000369732.4 UniProtKB/Swiss-Prot
Gene3D-CATH 3.10.50.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glycosidases UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000085465 GTEx
HGNC ID HGNC:8524 ENTREZGENE
Human Proteome Map OVGP1 Human Proteome Map
InterPro Chitinase_II UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Chitinase_insertion_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glyco_hydro18_cat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glycoside_hydrolase_SF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glycosyl_Hydrlase_18 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:5016 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 5016 ENTREZGENE
OMIM 603578 OMIM
PANTHER CHITINASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  OVIDUCT-SPECIFIC GLYCOPROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Glyco_hydro_18 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA32852 PharmGKB
PROSITE GH18_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART Glyco_18 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF51445 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF54556 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0AV19 ENTREZGENE
  B9EGE1 ENTREZGENE
  OVGP1_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
  Q15841 ENTREZGENE
  Q86YN0 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0AV19 UniProtKB/Swiss-Prot
  B9EGE1 UniProtKB/Swiss-Prot
  Q15841 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-17 OVGP1  oviductal glycoprotein 1  OVGP1  oviductal glycoprotein 1, 120kDa  Symbol and/or name change 5135510 APPROVED