TAS2R7 (taste 2 receptor member 7) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: TAS2R7 (taste 2 receptor member 7) Homo sapiens
Analyze
Symbol: TAS2R7
Name: taste 2 receptor member 7
RGD ID: 1347137
HGNC Page HGNC:14913
Description: Enables bitter taste receptor activity. Involved in detection of chemical stimulus involved in sensory perception of bitter taste. Predicted to be located in plasma membrane. Predicted to be active in membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: MGC142121; T2R7; taste receptor family B member 4; taste receptor type 2 member 7; taste receptor, family B, member 4; taste receptor, type 2, member 7; TRB4
RGD Orthologs
Mouse
Rat
Bonobo
Dog
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Related Pseudogenes: AC006518.1   AC244131.1   TAS2R18P   TAS2R2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381210,801,532 - 10,802,627 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1210,801,532 - 10,802,627 (-)EnsemblGRCh38hg38GRCh38
GRCh371210,954,131 - 10,955,226 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361210,845,398 - 10,846,493 (-)NCBINCBI36Build 36hg18NCBI36
Build 341210,845,479 - 10,846,436NCBI
Celera1216,102,458 - 16,103,553 (-)NCBICelera
Cytogenetic Map12p13.2NCBI
HuRef1210,682,929 - 10,684,024 (-)NCBIHuRef
CHM1_11210,923,509 - 10,924,604 (-)NCBICHM1_1
T2T-CHM13v2.01210,674,613 - 10,675,708 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (IBA,IC,IEA)
plasma membrane  (IEA,TAS)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. A novel family of mammalian taste receptors. Adler E, etal., Cell 2000 Mar 17;100(6):693-702.
2. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10761935   PMID:10766242   PMID:10774719   PMID:11696554   PMID:12139982   PMID:12477932   PMID:12581520   PMID:15489334   PMID:15496549   PMID:15744053   PMID:20022913   PMID:21873635  
PMID:26186194   PMID:28514442   PMID:29355483   PMID:30928101   PMID:31066447   PMID:31781630   PMID:33961781  


Genomics

Comparative Map Data
TAS2R7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381210,801,532 - 10,802,627 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1210,801,532 - 10,802,627 (-)EnsemblGRCh38hg38GRCh38
GRCh371210,954,131 - 10,955,226 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361210,845,398 - 10,846,493 (-)NCBINCBI36Build 36hg18NCBI36
Build 341210,845,479 - 10,846,436NCBI
Celera1216,102,458 - 16,103,553 (-)NCBICelera
Cytogenetic Map12p13.2NCBI
HuRef1210,682,929 - 10,684,024 (-)NCBIHuRef
CHM1_11210,923,509 - 10,924,604 (-)NCBICHM1_1
T2T-CHM13v2.01210,674,613 - 10,675,708 (-)NCBIT2T-CHM13v2.0
Tas2r130
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396131,606,855 - 131,607,793 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6131,606,786 - 131,607,875 (-)EnsemblGRCm39 Ensembl
GRCm386131,629,892 - 131,630,830 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6131,629,823 - 131,630,912 (-)EnsemblGRCm38mm10GRCm38
MGSCv376131,579,910 - 131,580,848 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366131,595,585 - 131,596,523 (-)NCBIMGSCv36mm8
Celera6134,191,677 - 134,192,615 (+)NCBICelera
Cytogenetic Map6F3NCBI
cM Map663.44NCBI
Tas2r130
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84167,004,245 - 167,005,183 (-)NCBIGRCr8
mRatBN7.24165,272,827 - 165,273,765 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4165,272,827 - 165,273,765 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4171,557,611 - 171,558,549 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04167,340,632 - 167,341,570 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04165,974,678 - 165,975,616 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04165,746,263 - 165,747,201 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4165,746,263 - 165,747,201 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04228,309,823 - 228,310,761 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44169,227,316 - 169,228,254 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera4153,873,610 - 153,874,548 (-)NCBICelera
Cytogenetic Map4q42NCBI
TAS2R7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21016,273,046 - 16,274,149 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11216,269,802 - 16,270,905 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01210,830,201 - 10,831,292 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11211,095,949 - 11,097,408 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1211,096,369 - 11,097,346 (-)Ensemblpanpan1.1panPan2
TAS2R7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12734,898,964 - 34,899,902 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2734,898,964 - 34,899,902 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2711,548,545 - 11,549,483 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02735,207,136 - 35,208,074 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2735,207,136 - 35,208,074 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12735,097,081 - 35,098,019 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02735,046,941 - 35,047,879 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02711,276,771 - 11,277,709 (-)NCBIUU_Cfam_GSD_1.0
TAS2R7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl561,262,331 - 61,263,269 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1561,262,331 - 61,263,269 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2563,985,142 - 63,986,080 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TAS2R7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11110,620,380 - 10,623,225 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1110,621,391 - 10,622,347 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660892,698,819 - 2,699,903 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in TAS2R7
26 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 12p13.33-11.22(chr12:121055-28415184)x1 copy number loss See cases [RCV000052776] Chr12:121055..28415184 [GRCh38]
Chr12:282465..28568117 [GRCh37]
Chr12:100482..28459384 [NCBI36]
Chr12:12p13.33-11.22
pathogenic
GRCh38/hg38 12p13.33-11.1(chr12:77187-34380176)x3 copy number gain See cases [RCV000053660] Chr12:77187..34380176 [GRCh38]
Chr12:282465..34533111 [GRCh37]
Chr12:56614..34424378 [NCBI36]
Chr12:12p13.33-11.1
pathogenic
GRCh38/hg38 12p13.33-12.1(chr12:80412-25470329)x3 copy number gain See cases [RCV000053662] Chr12:80412..25470329 [GRCh38]
Chr12:282465..25623263 [GRCh37]
Chr12:59839..25514530 [NCBI36]
Chr12:12p13.33-12.1
pathogenic
GRCh38/hg38 12p13.33-11.1(chr12:212976-33926913)x4 copy number gain See cases [RCV000053666] Chr12:212976..33926913 [GRCh38]
Chr12:322142..34079848 [GRCh37]
Chr12:192403..33971115 [NCBI36]
Chr12:12p13.33-11.1
pathogenic
NM_023919.2(TAS2R7):c.914C>G (p.Ser305Cys) single nucleotide variant Malignant melanoma [RCV000069804] Chr12:10801657 [GRCh38]
Chr12:10954256 [GRCh37]
Chr12:10845523 [NCBI36]
Chr12:12p13.2
not provided
NM_023919.2(TAS2R7):c.144C>T (p.Leu48=) single nucleotide variant Malignant melanoma [RCV000069805] Chr12:10802427 [GRCh38]
Chr12:10955026 [GRCh37]
Chr12:10846293 [NCBI36]
Chr12:12p13.2
not provided
NM_023919.2(TAS2R7):c.78C>T (p.Phe26=) single nucleotide variant Malignant melanoma [RCV000062391] Chr12:10802493 [GRCh38]
Chr12:10955092 [GRCh37]
Chr12:10846359 [NCBI36]
Chr12:12p13.2
not provided
GRCh38/hg38 12p13.33-11.1(chr12:121255-34603274)x3 copy number gain See cases [RCV000136611] Chr12:121255..34603274 [GRCh38]
Chr12:282465..34756209 [GRCh37]
Chr12:100682..34647476 [NCBI36]
Chr12:12p13.33-11.1
pathogenic
GRCh38/hg38 12p13.33-12.3(chr12:2871741-14987348)x3 copy number gain See cases [RCV000137694] Chr12:2871741..14987348 [GRCh38]
Chr12:2980907..15140282 [GRCh37]
Chr12:2851168..15031549 [NCBI36]
Chr12:12p13.33-12.3
pathogenic
GRCh38/hg38 12p13.33-11.1(chr12:121271-34603261)x3 copy number gain See cases [RCV000139052] Chr12:121271..34603261 [GRCh38]
Chr12:282465..34756196 [GRCh37]
Chr12:100698..34647463 [NCBI36]
Chr12:12p13.33-11.1
pathogenic
GRCh38/hg38 12p13.33-11.1(chr12:54427-34608071)x4 copy number gain See cases [RCV000139787] Chr12:54427..34608071 [GRCh38]
Chr12:282465..34761006 [GRCh37]
Chr12:33854..34652273 [NCBI36]
Chr12:12p13.33-11.1
pathogenic
GRCh38/hg38 12p13.33-q24.33(chr12:121271-133196807)x3 copy number gain See cases [RCV000139555] Chr12:121271..133196807 [GRCh38]
Chr12:282465..133773393 [GRCh37]
Chr12:100698..132283466 [NCBI36]
Chr12:12p13.33-q24.33
pathogenic
GRCh38/hg38 12p13.33-12.2(chr12:1258274-20657577)x3 copy number gain See cases [RCV000141905] Chr12:1258274..20657577 [GRCh38]
Chr12:1367440..20810511 [GRCh37]
Chr12:1237701..20701778 [NCBI36]
Chr12:12p13.33-12.2
pathogenic
GRCh38/hg38 12p13.33-11.1(chr12:64620-34682902)x4 copy number gain See cases [RCV000142149] Chr12:64620..34682902 [GRCh38]
Chr12:173786..34835837 [GRCh37]
Chr12:44047..34727104 [NCBI36]
Chr12:12p13.33-11.1
pathogenic
GRCh37/hg19 12p13.33-11.1(chr12:148034-34178799)x4 copy number gain See cases [RCV000240164] Chr12:148034..34178799 [GRCh37]
Chr12:12p13.33-11.1
pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:1-133851895)x3 copy number gain See cases [RCV000258805] Chr12:1..133851895 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic|likely pathogenic
chr12:10074776-18800953 complex variant complex Breast ductal adenocarcinoma [RCV000207105] Chr12:10074776..18800953 [GRCh37]
Chr12:12p13.31-12.3
uncertain significance
GRCh37/hg19 12p13.33-11.1(chr12:89061-34178799)x3 copy number gain See cases [RCV000240487] Chr12:89061..34178799 [GRCh37]
Chr12:12p13.33-11.1
pathogenic
GRCh37/hg19 12p13.33-q11(chr12:173786-37869301)x3 copy number gain See cases [RCV000449191] Chr12:173786..37869301 [GRCh37]
Chr12:12p13.33-q11
pathogenic
GRCh37/hg19 12p13.33-12.1(chr12:173786-25286865)x3 copy number gain See cases [RCV000449287] Chr12:173786..25286865 [GRCh37]
Chr12:12p13.33-12.1
pathogenic
GRCh37/hg19 12p13.33-11.1(chr12:173786-34835837)x3 copy number gain See cases [RCV000447551] Chr12:173786..34835837 [GRCh37]
Chr12:12p13.33-11.1
pathogenic
GRCh37/hg19 12p13.33-12.2(chr12:173786-20026080)x3 copy number gain See cases [RCV000446050] Chr12:173786..20026080 [GRCh37]
Chr12:12p13.33-12.2
pathogenic
GRCh37/hg19 12p13.33-11.1(chr12:189578-34756150) copy number gain See cases [RCV000446017] Chr12:189578..34756150 [GRCh37]
Chr12:12p13.33-11.1
pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:173787-133777902)x3 copy number gain See cases [RCV000510482] Chr12:173787..133777902 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:173787-133777902) copy number gain See cases [RCV000511643] Chr12:173787..133777902 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic
GRCh37/hg19 12p13.33-11.1(chr12:565369-34835837)x3 copy number gain See cases [RCV000511580] Chr12:565369..34835837 [GRCh37]
Chr12:12p13.33-11.1
likely pathogenic
GRCh37/hg19 12p13.33-13.2(chr12:173786-11677456)x3 copy number gain See cases [RCV000510853] Chr12:173786..11677456 [GRCh37]
Chr12:12p13.33-13.2
pathogenic
GRCh37/hg19 12p13.33-11.22(chr12:173786-28219229)x3 copy number gain See cases [RCV000510961] Chr12:173786..28219229 [GRCh37]
Chr12:12p13.33-11.22
pathogenic
NM_023919.2(TAS2R7):c.625C>T (p.Arg209Trp) single nucleotide variant not specified [RCV004288968] Chr12:10801946 [GRCh38]
Chr12:10954545 [GRCh37]
Chr12:12p13.2
likely benign
GRCh37/hg19 12p13.33-11.1(chr12:173786-34835837)x3 copy number gain not provided [RCV000683479] Chr12:173786..34835837 [GRCh37]
Chr12:12p13.33-11.1
pathogenic
GRCh37/hg19 12p13.33-q11(chr12:173786-37869107)x3 copy number gain not provided [RCV000683480] Chr12:173786..37869107 [GRCh37]
Chr12:12p13.33-q11
pathogenic
GRCh37/hg19 12p13.33-11.1(chr12:173786-34835837)x2,3 copy number gain not provided [RCV000683478] Chr12:173786..34835837 [GRCh37]
Chr12:12p13.33-11.1
pathogenic
GRCh37/hg19 12p13.2-13.1(chr12:10717428-14032860)x1 copy number loss not provided [RCV000683470] Chr12:10717428..14032860 [GRCh37]
Chr12:12p13.2-13.1
pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:191619-133777645)x3 copy number gain not provided [RCV000750246] Chr12:191619..133777645 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:621220-133779118)x3 copy number gain not provided [RCV000750253] Chr12:621220..133779118 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic
GRCh37/hg19 12p13.33-11.21(chr12:191619-31733044)x3 copy number gain not provided [RCV000750245] Chr12:191619..31733044 [GRCh37]
Chr12:12p13.33-11.21
pathogenic
NM_023919.2(TAS2R7):c.640C>T (p.Arg214Ter) single nucleotide variant not provided [RCV000948881] Chr12:10801931 [GRCh38]
Chr12:10954530 [GRCh37]
Chr12:12p13.2
benign
GRCh37/hg19 12p13.33-12.3(chr12:189216-15001420) copy number gain not provided [RCV000767817] Chr12:189216..15001420 [GRCh37]
Chr12:12p13.33-12.3
pathogenic
GRCh37/hg19 12p13.2-13.1(chr12:10336209-13535349) copy number loss Multiple endocrine neoplasia type 4 [RCV000767604] Chr12:10336209..13535349 [GRCh37]
Chr12:12p13.2-13.1
pathogenic
NM_023919.2(TAS2R7):c.599C>A (p.Ser200Tyr) single nucleotide variant not specified [RCV004285989] Chr12:10801972 [GRCh38]
Chr12:10954571 [GRCh37]
Chr12:12p13.2
uncertain significance
GRCh37/hg19 12p13.33-11.1(chr12:173786-34496628)x3 copy number gain not provided [RCV000847209] Chr12:173786..34496628 [GRCh37]
Chr12:12p13.33-11.1
pathogenic
GRCh37/hg19 12p13.33-q11(chr12:274676-37869301)x4 copy number gain not provided [RCV001006470] Chr12:274676..37869301 [GRCh37]
Chr12:12p13.33-q11
pathogenic
GRCh37/hg19 12p13.33-11.1(chr12:173786-34835837) copy number gain not specified [RCV002052957] Chr12:173786..34835837 [GRCh37]
Chr12:12p13.33-11.1
pathogenic
GRCh37/hg19 12p13.33-12.1(chr12:173786-25286865) copy number gain not specified [RCV002052955] Chr12:173786..25286865 [GRCh37]
Chr12:12p13.33-12.1
pathogenic
GRCh37/hg19 12p13.33-q11(chr12:173786-37869301) copy number gain not specified [RCV002052958] Chr12:173786..37869301 [GRCh37]
Chr12:12p13.33-q11
pathogenic
GRCh37/hg19 12p13.2-12.1(chr12:10853887-24103810)x1 copy number loss not provided [RCV002292878] Chr12:10853887..24103810 [GRCh37]
Chr12:12p13.2-12.1
pathogenic
NM_023919.2(TAS2R7):c.99G>A (p.Met33Ile) single nucleotide variant not specified [RCV004119257] Chr12:10802472 [GRCh38]
Chr12:10955071 [GRCh37]
Chr12:12p13.2
uncertain significance
NM_023919.2(TAS2R7):c.608T>C (p.Leu203Pro) single nucleotide variant not specified [RCV004137345] Chr12:10801963 [GRCh38]
Chr12:10954562 [GRCh37]
Chr12:12p13.2
uncertain significance
NM_023919.2(TAS2R7):c.262T>C (p.Phe88Leu) single nucleotide variant not specified [RCV004188788] Chr12:10802309 [GRCh38]
Chr12:10954908 [GRCh37]
Chr12:12p13.2
uncertain significance
NM_023919.2(TAS2R7):c.780G>T (p.Met260Ile) single nucleotide variant not specified [RCV004130035] Chr12:10801791 [GRCh38]
Chr12:10954390 [GRCh37]
Chr12:12p13.2
likely benign
NM_023919.2(TAS2R7):c.401T>A (p.Leu134Gln) single nucleotide variant not specified [RCV004159526] Chr12:10802170 [GRCh38]
Chr12:10954769 [GRCh37]
Chr12:12p13.2
uncertain significance
NM_023919.2(TAS2R7):c.302C>T (p.Thr101Ile) single nucleotide variant not specified [RCV004239706] Chr12:10802269 [GRCh38]
Chr12:10954868 [GRCh37]
Chr12:12p13.2
uncertain significance
NM_023919.2(TAS2R7):c.680C>T (p.Thr227Ile) single nucleotide variant not provided [RCV004695544]|not specified [RCV004167943] Chr12:10801891 [GRCh38]
Chr12:10954490 [GRCh37]
Chr12:12p13.2
uncertain significance
NM_023919.2(TAS2R7):c.491G>A (p.Arg164Lys) single nucleotide variant not specified [RCV004124893] Chr12:10802080 [GRCh38]
Chr12:10954679 [GRCh37]
Chr12:12p13.2
uncertain significance
NM_023919.2(TAS2R7):c.19A>C (p.Thr7Pro) single nucleotide variant not specified [RCV004237753] Chr12:10802552 [GRCh38]
Chr12:10955151 [GRCh37]
Chr12:12p13.2
uncertain significance
GRCh37/hg19 12p13.33-11.1(chr12:176047-34179852)x4 copy number gain Pallister-Killian syndrome [RCV003154827] Chr12:176047..34179852 [GRCh37]
Chr12:12p13.33-11.1
pathogenic
NM_023919.2(TAS2R7):c.246G>T (p.Met82Ile) single nucleotide variant not specified [RCV004262473] Chr12:10802325 [GRCh38]
Chr12:10954924 [GRCh37]
Chr12:12p13.2
uncertain significance
NM_023919.2(TAS2R7):c.504A>C (p.Leu168Phe) single nucleotide variant not specified [RCV004255030] Chr12:10802067 [GRCh38]
Chr12:10954666 [GRCh37]
Chr12:12p13.2
uncertain significance
NM_023919.2(TAS2R7):c.758T>C (p.Ile253Thr) single nucleotide variant not specified [RCV004364100] Chr12:10801813 [GRCh38]
Chr12:10954412 [GRCh37]
Chr12:12p13.2
uncertain significance
GRCh37/hg19 12p13.2(chr12:10588512-11788901)x3 copy number gain not provided [RCV003484864] Chr12:10588512..11788901 [GRCh37]
Chr12:12p13.2
uncertain significance
Single allele duplication not provided [RCV003448692] Chr12:188053..34856694 [GRCh37]
Chr12:12p13.33-11.1
pathogenic
GRCh37/hg19 12p13.33-11.1(chr12:173786-34835641)x3 copy number gain not specified [RCV003986979] Chr12:173786..34835641 [GRCh37]
Chr12:12p13.33-11.1
pathogenic
NM_023919.2(TAS2R7):c.409T>A (p.Cys137Ser) single nucleotide variant not specified [RCV004471501] Chr12:10802162 [GRCh38]
Chr12:10954761 [GRCh37]
Chr12:12p13.2
uncertain significance
NM_023919.2(TAS2R7):c.670G>A (p.Asp224Asn) single nucleotide variant not specified [RCV004471502] Chr12:10801901 [GRCh38]
Chr12:10954500 [GRCh37]
Chr12:12p13.2
uncertain significance
NM_023919.2(TAS2R7):c.924A>C (p.Lys308Asn) single nucleotide variant not specified [RCV004471503] Chr12:10801647 [GRCh38]
Chr12:10954246 [GRCh37]
Chr12:12p13.2
uncertain significance
NM_023919.2(TAS2R7):c.435C>A (p.Ser145Arg) single nucleotide variant not specified [RCV004681972] Chr12:10802136 [GRCh38]
Chr12:10954735 [GRCh37]
Chr12:12p13.2
uncertain significance
NM_023919.2(TAS2R7):c.868A>C (p.Asn290His) single nucleotide variant not specified [RCV004673282] Chr12:10801703 [GRCh38]
Chr12:10954302 [GRCh37]
Chr12:12p13.2
uncertain significance
NM_023919.2(TAS2R7):c.407G>A (p.Gly136Glu) single nucleotide variant not specified [RCV004673284] Chr12:10802164 [GRCh38]
Chr12:10954763 [GRCh37]
Chr12:12p13.2
uncertain significance
NM_023919.2(TAS2R7):c.478G>A (p.Val160Met) single nucleotide variant not specified [RCV004673285] Chr12:10802093 [GRCh38]
Chr12:10954692 [GRCh37]
Chr12:12p13.2
uncertain significance
NM_023919.2(TAS2R7):c.459C>A (p.Asn153Lys) single nucleotide variant not specified [RCV004673286] Chr12:10802112 [GRCh38]
Chr12:10954711 [GRCh37]
Chr12:12p13.2
uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:28
Count of miRNA genes:28
Interacting mature miRNAs:28
Transcripts:ENST00000240687
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
TAS2R7__5213  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371210,954,042 - 10,954,862UniSTSGRCh37
Build 361210,845,309 - 10,846,129RGDNCBI36
Celera1216,102,369 - 16,103,189RGD
HuRef1210,682,840 - 10,683,660UniSTS
UniSTS:485587  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371210,954,131 - 10,955,226UniSTSGRCh37
Celera1216,102,458 - 16,103,553UniSTS
HuRef1210,682,929 - 10,684,024UniSTS
UniSTS:480718  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371210,954,213 - 10,955,169UniSTSGRCh37
Celera1216,102,540 - 16,103,496UniSTS
HuRef1210,683,011 - 10,683,967UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
59 140 210 148 703 158 167 32 112 19 115 499 423 10 630 48 167 128 13

Sequence


Ensembl Acc Id: ENST00000240687   ⟹   ENSP00000240687
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1210,801,532 - 10,802,627 (-)Ensembl
RefSeq Acc Id: NM_023919   ⟹   NP_076408
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381210,801,532 - 10,802,627 (-)NCBI
GRCh371210,954,131 - 10,955,226 (-)RGD
Build 361210,845,398 - 10,846,493 (-)NCBI Archive
Celera1216,102,458 - 16,103,553 (-)RGD
HuRef1210,682,929 - 10,684,024 (-)RGD
CHM1_11210,923,509 - 10,924,604 (-)NCBI
T2T-CHM13v2.01210,674,613 - 10,675,708 (-)NCBI
Sequence:
RefSeq Acc Id: NP_076408   ⟸   NM_023919
- UniProtKB: Q9NYW3 (UniProtKB/Swiss-Prot),   Q645Y1 (UniProtKB/Swiss-Prot),   Q50KV5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSP00000240687   ⟸   ENST00000240687
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9NYW3-F1-model_v2 AlphaFold Q9NYW3 1-318 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:14913 AgrOrtholog
COSMIC TAS2R7 COSMIC
Ensembl Genes ENSG00000121377 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSG00000273326 UniProtKB/Swiss-Prot
  ENSG00000274327 UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000240687 ENTREZGENE
  ENST00000240687.2 UniProtKB/Swiss-Prot
  ENST00000574656.1 UniProtKB/Swiss-Prot
  ENST00000613239.1 UniProtKB/Swiss-Prot
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000121377 GTEx
  ENSG00000273326 GTEx
  ENSG00000274327 GTEx
HGNC ID HGNC:14913 ENTREZGENE
Human Proteome Map TAS2R7 Human Proteome Map
InterPro GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  T2R UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:50837 UniProtKB/Swiss-Prot
NCBI Gene 50837 ENTREZGENE
OMIM 604793 OMIM
PANTHER PTHR11394:SF58 UniProtKB/Swiss-Prot
  TASTE RECEPTOR TYPE 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TASTE RECEPTOR TYPE 2 MEMBER 7 UniProtKB/TrEMBL
Pfam TAS2R UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA37925 PharmGKB
PROSITE G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt Q50KV5 ENTREZGENE, UniProtKB/TrEMBL
  Q645Y1 ENTREZGENE
  Q9NYW3 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q645Y1 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-22 TAS2R7  taste 2 receptor member 7    taste receptor, type 2, member 7  Symbol and/or name change 5135510 APPROVED